Core Viewpoint - Three pharmaceutical companies, Xianju Pharmaceutical, Tianjin Pharmaceutical, and Lianhuan Pharmaceutical, have been penalized for monopolistic practices related to the raw material dexamethasone sodium phosphate, with total fines amounting to approximately 325 million yuan [1][2][3]. Group 1: Penalties and Financial Impact - Xianju Pharmaceutical was fined a total of approximately 195 million yuan, which includes the confiscation of illegal gains of 23.74 million yuan and a fine of about 172 million yuan based on 8% of its 2023 sales [2][5]. - Tianjin Pharmaceutical faced penalties totaling approximately 69.19 million yuan, including the confiscation of illegal gains of 42.76 million yuan and a reduced fine of about 13.2 million yuan after an 80% reduction [3][5]. - Lianhuan Pharmaceutical was fined approximately 61.04 million yuan, which includes the confiscation of illegal gains of 17.89 million yuan and a reduced fine of about 61.63 million yuan after a 30% reduction [3][5]. Group 2: Profitability Impact - The fines significantly impact the profitability of the companies, with Tianjin Pharmaceutical's penalties representing 2.15% of its recent audited revenue and 51.85% of its net profit attributable to shareholders [5]. - For Xianju Pharmaceutical, the total fine of 195 million yuan accounts for 4.87% of its projected 2024 revenue of 4 billion yuan and 49.17% of its net profit of 397 million yuan [5]. - Lianhuan Pharmaceutical's proposed fines represent 72.53% of its net profit of 84 million yuan for the previous year [5]. Group 3: Recurrence of Violations - Tianjin Pharmaceutical has been penalized for monopolistic behavior for the fourth time in four years, with cumulative fines exceeding 170 million yuan [6][7].

Core Viewpoint - Four companies engaged in a price-fixing conspiracy for dexamethasone phosphate raw materials, leading to significant price increases and resulting in administrative penalties exceeding 350 million yuan [1][5][15] Group 1: Companies Involved - The companies involved in the price-fixing conspiracy are Tianjin Pharmaceutical Industry Co., Ltd. (津药药业), Xianju Pharmaceutical Co., Ltd. (仙琚制药), Lianhuan Pharmaceutical Co., Ltd. (联环药业), and Xi'an Guokang Ruijin Pharmaceutical Co., Ltd. (西安国康瑞金) [1][5][14] - The main organizer of the conspiracy was identified as an individual named Guo, who facilitated communication and coordination among the companies [5][6] Group 2: Price Changes - The price of dexamethasone phosphate raw materials increased from several thousand yuan per kilogram to over ten thousand yuan, with some companies raising prices as high as 38,000 yuan per kilogram [1][10][14] - Specific price increases included Tianjin Pharmaceutical raising prices from a maximum of 9,000 yuan to 13,800 yuan per kilogram, and Xi'an Guokang Ruijin increasing prices from 7,900 yuan to between 10,000 and 38,000 yuan per kilogram [10][14] Group 3: Administrative Penalties - The total penalties imposed on the companies amounted to over 350 million yuan, with Tianjin Pharmaceutical fined 69.19 million yuan, Xianju Pharmaceutical fined 195.3 million yuan, and Xi'an Guokang Ruijin fined 28.78 million yuan [1][12][13] - Lianhuan Pharmaceutical is expected to face a fine of 61.04 million yuan, with a proposed reduction of 30% due to its cooperation during the investigation [1][11] Group 4: Cooperation and Leniency - Tianjin Pharmaceutical was the first to submit a leniency application, providing crucial evidence and reporting the details of the price-fixing agreement, which led to an 80% reduction in its fine [2][11] - In contrast, Xianju Pharmaceutical and Xi'an Guokang Ruijin did not submit leniency applications, resulting in no reductions in their fines [2][12][14]

文/梧桐兄弟 值得注意的是，因同一事项一并受罚的还有 津药药业（600488.SH）和联环药业（600513.SH） ，分别被罚 没6,919.24万元、6,103.82万元。 天津市市场监督管理委员会决定责令公司停止违法行为，对公司作出行政处罚如下：（一）没收违法所得人 民币23,746,680.00元。 （二）并处2023年销售额8%的罚款 171,550,232.22 元，以上罚没款合计人民币 195,296,912.22元。 近期，仙琚制药（002332）披露公告，公司收到天津市市场监督管理委员会下发的《行政处罚决定书》， 公司与具有竞争关系的其他经营者，以垄断协议形式变更、固定地塞米松磷酸钠原料药价格，排除限制了地 塞米松磷酸钠原料药销售领域的竞争， 违反了《中华人民共和国反垄断法》第十七条第(一)项的规定， 属 于达成并实施"固定或者变更商品价格"垄断协议的行为， 应当依据《反垄断法》第五十六条的规定依法追 究法律责任。 ...

Group 1 - China National Pharmaceutical plans to acquire 100% equity of Jinsui Technology for 302 million yuan to enhance marketing and supply chain management capabilities [1] - The acquisition aims to strengthen the company's e-commerce platform, product pipeline, and marketing strategies, potentially boosting investor confidence and stock performance [1] Group 2 - Tianjin Pharmaceutical responded to an inquiry regarding its 2024 annual report, highlighting strategic R&D collaborations and significant reductions in sales expenses due to policy changes and marketing upgrades [2] - The reduction in sales expenses indicates improved cost control and operational efficiency, which may positively impact investor confidence and stock valuation [2] Group 3 - President Trump announced plans to sign an executive order aimed at reducing prescription drug prices by 30% to 80%, aligning U.S. drug prices with the lowest global prices [3] - A significant drop in U.S. drug prices could pressure domestic pharmaceutical companies' export businesses, but innovative domestic firms may leverage unique advantages to mitigate risks [3] Group 4 - Fosun Pharma's FCN-159 tablet has been included in the breakthrough therapy designation program, indicating strong R&D capabilities and market potential for treating rare diseases and tumors [4] - The breakthrough designation may accelerate the drug's development and approval process, enhancing investor confidence and potentially increasing the company's market competitiveness [4] Group 5 - Rongchang Biopharma's ADC drug, RC48, has successfully met primary endpoints in a Phase III clinical trial for treating advanced or metastatic urothelial carcinoma [5] - The successful trial results may expand the drug's indications and significantly enhance its market competitiveness and commercial value, attracting investor interest [6]

证券代码：600488 证券简称：津药药业 编号：2025-032 | | 月 | | 年 | | | 年 | 09 月 | | | | 9 月申报受 | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 理，正在技术审评中。 | | | | | | | | | | | | | 富马酸福莫特 期研发与生产验证，已通过技术 | | 2019 年 | 2 5-7 | | | | 2019 年 | 03 月-2021 | | | 经过前 | | 罗 | | 月 | 年 | | | | 年 02 月 | | | | 审评， | | 2025 年 | 1 月已转无形资产。 | | | | | | | | | | | | | 月 | | 年 | | | | | | | | 证。 | | | 月 | | 年 | | | | 年 01 月 | 0 | | | 户提出需求 | | 时配合进行生产验证。 | | | | | | | | | | | | | | | | | | | | | | | | 经过前期研发工 | | 艺路线 ...

贵所《关于津药药业股份有限公司 2024 年年度报告的事后审核问询函》 （上证公函【2025】0389 号）（以下简称"事后审核问询函"）已收悉。 根据贵所事后审核问询函的要求，中审华会计师事务所（特殊普通合伙） （以下简称"年审会计师"）作为津药药业股份有限公司（以下简称"公 司"）本次年度报告的审计机构，会同公司对事后审核问询函中所提问题 进行了讨论，对相关事项进行了审慎核查并发表意见，现汇报如下： 一、关于研发项目款。年报及公告显示，公司与天津药业研究院股份 有限公司、北京华众恩康医药技术有限公司、津药永光（河北）制药有限 公司、天津市医药集团技术发展有限公司等控股股东附属企业存在大额预 付研发款，2024 年累计发生预付约 0.2 亿元，大股东及其附属企业 2024 年 累计偿还约 0.7 亿元，期末余额约 1.6 亿元。 请公司补充披露： （1）公司委托控股股东及其附属企业研发的主要内容及必要性，列示 各研发项目的启动时间、研发周期、预算总额、预付金额及预付时间、合 同约定的支付进度、实际研发开支，以及目前进展及状态，并说明大额预 付研发预付款且长期挂账的合理性，公司与控股股东及其附属企业相关往 来 ...

证券代码：600488 证券简称：津药药业 编号：2025-032 津药药业股份有限公司 关于 2024 年年度报告的事后审核问询函的回复公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连带责任。 近日，津药药业股份有限公司（以下简称"公司"）收到上海证券交 易所上市公司管理一部下发的《关于津药药业股份有限公司 2024 年年度报 告的事后审核问询函》（上证公函【2025】0389 号），根据上海证券交易 所的要求，公司积极组织相关各方核实有关情况，现回复如下： 一、关于研发项目款。年报及公告显示，公司与天津药业研究院股份 有限公司、北京华众恩康医药技术有限公司、津药永光（河北）制药有限 公司、天津市医药集团技术发展有限公司等控股股东附属企业存在大额预 付研发款，2024 年累计发生预付约 0.2 亿元，大股东及其附属企业 2024 年 累计偿还约 0.7 亿元，期末余额约 1.6 亿元。 请公司补充披露： （1）公司委托控股股东及其附属企业研发的主要内容及必要性，列示 各研发项目的启动时间、研发周期、预算总额、预付金额及预付 ...

Core Viewpoint - A significant antitrust fine exceeding 350 million yuan has been imposed on four pharmaceutical companies for colluding to raise the price of dexamethasone phosphate sodium raw materials, with the fines totaling approximately 354 million yuan [1][6][11]. Group 1: Companies Involved - The companies involved in the antitrust case include Zhejiang Xianju Pharmaceutical Co., Ltd., Tianjin Pharmaceutical Co., Ltd., Jiangsu Lianhuan Pharmaceutical Co., Ltd., and Xi'an Guokang Ruijin Pharmaceutical Co., Ltd. [1][4][6] - Zhejiang Xianju Pharmaceutical received the highest penalty of approximately 195 million yuan, which includes the confiscation of illegal gains and a fine based on 8% of its 2023 sales [3][4]. - Tianjin Pharmaceutical was fined approximately 69.19 million yuan, while Jiangsu Lianhuan was fined around 61.04 million yuan [1][4]. Group 2: Details of the Antitrust Violations - The antitrust violations occurred over a period of two years and four months, during which the companies engaged in price-fixing and supply manipulation of dexamethasone phosphate sodium, a critical medication during the COVID-19 pandemic [5][7][9]. - The companies collectively agreed to raise prices and implemented a supply cut, leading to increased costs for downstream formulations [9][11]. - The price of dexamethasone phosphate sodium was raised significantly, with Xianju Pharmaceutical increasing its price from 8,200 yuan to 10,000 yuan per kilogram, and other companies following suit with similar price hikes [8][11]. Group 3: Individual Accountability - The antitrust enforcement agency has also pursued individual accountability, imposing fines on three company executives of 600,000 yuan each, and an additional 500,000 yuan fine on the individual who organized the collusion, Guo Xiangguo [10][12]. - This case marks a continuation of the trend towards holding individuals accountable for corporate antitrust violations, reinforcing the importance of compliance within the industry [12][13].

Core Viewpoint - The company plans to hold an investor briefing on May 16, 2025, to discuss its 2024 annual performance and financial results, allowing for interactive communication with investors [2][3]. Group 1: Meeting Details - The investor briefing is scheduled for May 16, 2025, from 13:00 to 14:45 [4]. - The meeting will take place at the Shanghai Stock Exchange Roadshow Center and will be conducted via video live streaming and online interaction [4]. - Investors can participate by logging into the Roadshow Center during the specified time [4]. Group 2: Participation and Interaction - Investors can submit questions from May 9, 2025, to May 15, 2025, through the Roadshow Center's website or via the company's email [5]. - The company will address commonly asked questions during the briefing [5]. - Contact information for inquiries includes a designated contact person and email address [5]. Group 3: Attendees - Key attendees of the briefing will include the Chairman, General Manager, Independent Directors, Chief Financial Officer, and Board Secretary [4].

证券代码：600488 证券简称：津药药业 编号：2025-031 津药药业股份有限公司 关于召开 2024 年度业绩说明会的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连带责任。 重要内容提示： 投资者可于2025年05月09日（星期五）至05月15日（星期四） 16:00期间登录上证路演中心网站首页点击"提问预征集"栏目 或通过公司邮箱（tjpc600488@vip.sina.com）进行提问。公司将 在说明会上对投资者普遍关注的问题进行回答。 津药药业股份有限公司（以下简称"公司"）已于2025年3 月27日发布公司2024年年度报告，为便于广大投资者更全面深入 地了解公司2024年度经营成果、财务状况，公司计划于2025年5 月16日（星期五）13:00-14:45举行2024年度业绩说明会，就投资 者关心的问题进行交流。 一、说明会类型 本次投资者说明会以视频结合网络互动的形式召开，公司将 针对2024年度的经营成果及财务指标的具体情况与投资者进行 互动交流和沟通，在信息披露允许的范围内就投资者普遍关注的 问题进 ...