Summary of WuXi AppTec Conference Call Company Overview - **Company**: WuXi AppTec - **Year**: 2024 - **Industry**: Pharmaceutical and Biotechnology Services Key Financial Performance - **2024 Revenue**: 39.24 billion RMB, a 5.2% increase year-over-year after excluding COVID-19 commercialization projects [3][4] - **Fourth Quarter Revenue**: 11.54 billion RMB, a 6.9% year-over-year increase [3] - **Adjusted Non-IFRS Net Profit**: 10.58 billion RMB, a 2.5% decrease year-over-year, but net profit margin increased to 27%, a historical high [4][12] - **Total Orders**: 49.31 billion RMB, a 47% increase year-over-year, indicating strong future revenue potential [4][5] Client and Market Dynamics - **Active Clients**: Approximately 6,000, with 5,500 in ongoing operations, a decrease of 500 due to the termination of certain ATU and medical testing businesses [5] - **Top 20 Global Pharmaceutical Clients**: Revenue increased by 24.1%, with U.S. and European revenues growing by 7.7% and 14.4%, respectively; however, revenues in China and Japan/Korea declined [6] Capacity Expansion and Investment - **Capacity Expansion**: By the end of 2025, small molecule API reactor volume is expected to exceed 4 million liters, and peptide solid-phase synthesis reactor volume is projected to exceed 100,000 liters [4][7] - **Capital Expenditure**: Expected to be between 7 billion to 8 billion RMB in 2025, with a focus on expanding domestic and international DNA capacity [18][38] Business Segments Performance - **Wuxi Chemical Services**: Revenue of 29.05 billion RMB, an 11.2% increase year-over-year after excluding COVID-19 projects, with an adjusted IFS gross margin of 46.4% [4][9] - **Testing Services**: Revenue decreased by 34.8% to 5.67 billion RMB, with a gross margin decline to 33.3% [10] - **CRO and SMO**: Continued to lead in clinical trials, with significant contributions to new drug approvals [11] Strategic Initiatives - **Sustainability Achievements**: Recognition from global institutions, including a 3A MSCI rating and inclusion in the Dow Jones Sustainability Index [8] - **AI and Digitalization**: Ongoing integration of AI and digital technologies to enhance operational efficiency and insights [25] Future Outlook - **2025 Revenue Guidance**: Expected growth of 10% to 15%, with overall revenue projected to reach between 41.5 billion to 43 billion RMB [4][14] - **Dividend Policy**: The board has decided to maintain a 30% annual dividend payout ratio and issue a one-time special cash dividend of 1 billion RMB [4][14] Risks and Challenges - **Market Fluctuations**: Revenue from China and Japan/Korea markets has seen declines, with recovery expected to take time [40][41] - **Impact of Tariffs**: Uncertainty regarding the impact of tariffs on business and profit margins, with ongoing monitoring of legislative developments [22][36] Conclusion WuXi AppTec demonstrated solid financial performance in 2024, with significant growth in orders and a strong outlook for 2025. The company is actively expanding its capacity and investing in sustainable practices while navigating challenges in certain markets.

药明康德2024年实现收入392亿元 多肽药物爆火带动业绩增长 3月17日晚间，药明康德（603259）(603259.SH，股价69.68元，市值2012亿元)发布了2024年年报。公司2024年实现营业收入392.41亿元，剔除新冠商业 化项目后同比增长5.2%；实现归母净利润94.5亿元。 从具体业务看，TIDES(寡核苷酸和多肽)业务保持高速增长，成为业绩驱动引擎。公司管理层在电话会上表示，目前公司平台上有超过20个GLP-1项目 管线，占整个市场份额20%以上，这些管线将产生更多的GLP-1产品，也会对产能有需求。因此，公司有信心产能将来能够被充分利用。 另外，针对投资者关注的AI(人工智能)技术在医药行业的应用，药明康德方面表示，在药物行业，尤其是研发阶段，公司正在探索如何应用AI加速创新 药物研发，但这还在比较早期的阶段。 营收剔除新冠商业化项目后增长5.2%美国地区客户贡献主要收入 3月17日晚间，药明康德发布了2024年年报。2024年，公司完成年初所设定的经营目标，营业收入为392.41亿元，剔除新冠商业化项目后同比增长 5.2%；实现归母净利润94.5亿元。 从具体业务看，TIDES业务 ...

Investment Rating - The investment rating for WuXi AppTec is maintained as "Buy" for both A and H shares [6][7]. Core Views - The company reported a revenue of 39.24 billion RMB for 2024, a decrease of 2.7% year-on-year, but a growth of 5.2% year-on-year when excluding COVID-19 impacts, which aligns with expectations [1]. - The net profit attributable to shareholders for 2024 was 9.45 billion RMB, down 1.6% year-on-year, while the adjusted non-IFRS net profit was 10.58 billion RMB, a decrease of 2.5% year-on-year [1]. - The company has seen a significant increase in its order backlog, with expectations for accelerated growth in 2025-2026, leading to a positive outlook [1][2]. Summary by Sections Financial Performance - In Q4 2024, revenue increased by 6.9% year-on-year, and net profit attributable to shareholders surged by 90.6% year-on-year, driven by improved operational efficiency and favorable exchange rate fluctuations [1]. - The company’s gross margin improved to 43.5% in Q4 2024 from 40.9% in Q4 2023 [1]. Order Backlog and Growth Prospects - As of the end of 2024, the order backlog reached 49.31 billion RMB, reflecting a year-on-year growth of 47.0% [2]. - The TIDES segment showed remarkable growth, with order backlog increasing by 104% year-on-year [2]. Segment Performance - WuXi Chemistry reported a revenue of 29.05 billion RMB in 2024, a slight decrease of 0.4% year-on-year, but a growth of 11.2% year-on-year when excluding COVID-19 impacts [3]. - The CDMO segment generated 17.87 billion RMB, with a year-on-year growth of 6.4% when excluding COVID-19 impacts [3]. Profitability Forecast - The forecast for net profit attributable to shareholders for 2025-2027 is 11.79 billion RMB, 13.56 billion RMB, and 16.74 billion RMB, representing year-on-year growth rates of 24.8%, 14.95%, and 23.5% respectively [5]. - The company’s target prices are set at 89.42 RMB for A shares and 100.99 HKD for H shares, based on a sum-of-the-parts valuation [5][6]. Valuation - The company is valued at 258.24 billion RMB for A shares and 291.66 billion HKD for H shares, reflecting adjustments due to changes in the DDSU segment [11].

证券研究报告 公司研究 [Table_ReportType] 公司点评报告 [Table_StockAndRank] 药明康德(603259) [Table_Author] 唐爱金 医药首席分析师 执业编号：S1500523080002 邮 箱：tangaijin@cindasc.com 贺鑫 医药行业分析师 执业编号：S1500524120003 邮 箱：hexin1@cindasc.com 相关研究 [Table_OtherReport] 维持全年指引不变，TIDES 业务逆势增 长 药明康德(603259)：高基数下稳定增 长，盈利能力持续提升 药明康德(603259)：业绩符合预期， 多业务协同稳健发展 信达证券股份有限公司 CINDA SECURITIES CO.,LTD 北京市西城区宣武门西大街甲127号金隅大厦B [Table_Title] 业绩边际改善趋势明确，2025 年有望实现双 位数增长 [Table_ReportDate] 2025 年 03 月 18 日 [Table_S 事件：2025 ummar年y]3 月 17 日，公司发布《2024 年年度报告》。2024 年公司实 现营业收 ...

Investment Rating - The report maintains a positive outlook for WuXi AppTec, indicating a potential for double-digit growth in 2025 [2][3]. Core Insights - The company achieved a revenue of 39.24 billion yuan in 2024, a decrease of 2.7% year-on-year, but a 5.2% increase when excluding COVID-19 commercialization projects. The net profit attributable to shareholders was 9.45 billion yuan, down 1.6% year-on-year, while the adjusted net profit increased by 2.5% to 9.99 billion yuan [1][2]. - The revenue for Q4 2024 was 11.54 billion yuan, reflecting a quarter-on-quarter growth of 10.3% and a year-on-year growth of 6.9%. The adjusted net profit for Q4 was 3.24 billion yuan, up 20.4% year-on-year [2][3]. - The company expects revenue from continuing operations to return to double-digit growth in 2025, with a projected revenue of 41.5 to 43 billion yuan, representing a growth of 10% to 15% [2][3]. Summary by Sections Financial Performance - In 2024, the company reported quarterly revenues of 7.98 billion yuan, 9.26 billion yuan, 10.46 billion yuan, and 11.54 billion yuan, with adjusted net profits of 1.91 billion yuan, 2.46 billion yuan, 2.97 billion yuan, and 3.24 billion yuan respectively [2]. - The total revenue for 2024 was 39.24 billion yuan, with a year-on-year growth rate of -2.7%. The adjusted net profit was 10.58 billion yuan, down 2.5% year-on-year [1][2]. Business Segments - The chemical business generated 29.05 billion yuan in 2024, a slight decline of 0.4%, but a growth of 11.2% when excluding specific commercialization projects. The TIDES business saw a significant revenue increase of 70.1% to 5.8 billion yuan [3][4]. - The testing business reported a revenue of 5.67 billion yuan, down 4.8% year-on-year, primarily due to a decline in order prices [4][5]. - The biological business achieved a revenue of 2.54 billion yuan, with a 29.9% growth in non-tumor-related areas [5][6]. Future Outlook - The company plans to increase capital expenditures to 7 to 8 billion yuan in 2025, focusing on expanding global D&M capacity [7]. - Revenue projections for 2025 to 2027 are 42.32 billion yuan, 47.08 billion yuan, and 52.24 billion yuan respectively, with net profits expected to reach 11.02 billion yuan, 12.50 billion yuan, and 14.09 billion yuan [8][9].

28.35亿元+10亿元，药明康德大手笔分红！ 3月17日晚间，无锡药明康德新药开发股份有限公司（以下简称"药明康德"，股票代码：603259） 发布2024年年度报告称，公司2024年实现营业收入392.41亿元，剔除新冠商业化项目同比增长5.2%；实 现归属于上市公司股东的净利润94.50亿元，2024年全年已完成年初所设定的经营目标。单季度来看， 第四季度收入创下单季度历史新高。此外，公司全年自由现金流达到历史新高79.8亿元。 值得一提的是，为持续激励保留人才，药明康德发布了2025年H股奖励信托计划（草案），在2025 年营业收入完成420亿元时，将授予15亿港元H股，并在达到430亿元及以上时，将额外授予10亿港元H 股。（记者 李亚男） 免责声明：以上内容为本网站转自其它媒体，相关信息仅为传递更多信息之目的，不代表本网观 点，亦不代表本网站赞同其观点或证实其内容的真实性。如稿件版权单位或个人不想在本网发布，可与 本网联系，本网视情况可立即将其撤除。 供稿：吕怡蕾 编辑：康书源 审核：吴娜 根据2024年度分红预案，公司拟向全体股东每10股派发现金红利9.8169元（含税），以目前公司总 股本测算 ...

港股创新药ETF（159567）紧密跟踪港股通创新药指数（987018），该指数反映港股通生物科技产 业上市公司的运行特征。 消息面上，药明康德公告，公司2024年第四季度收入与经调整non-IFRS归母净利润均创历史新高。 同时，公司还公布了10亿元回购计划，将用于注销并减少公司注册资本，回购价格不超过92.05元/股。 3月18日，港股市场集体高开。截至发稿，恒生科技指数涨幅扩大至3%，恒生指数涨超2.1%。其 中，医疗保健行业涨幅明显。 相关ETF方面，港股创新药ETF（159567）盘中涨逾4%，换手率超20%。成分股方面，药明康德一 度涨超15%，现涨13.3%，药明合联、药明生物涨幅随后，康诺亚-B、乐普生物-B等多股涨超5%。 资金流入情况方面，3月17日港股创新药ETF（159567）"吸金"346万元。wind金融终端数据显示， 该ETF最新流通规模为5.34亿元，最新流通份额为4.64亿份，均续创历史新高。 港股创新药ETF（159567）盘中涨逾4%，药明康德 涨超13%，机构：继续关注港股Biotech方向 民生证券指出，继续关注港股Biotech方向，医药板块整体进入基本面复苏、优质 ...

与此同时，公司也进行了扩产，2024年底，多肽固相合成反应釜总体积增加至4.1万升，预计2025年底 将进一步提升至超10万升。 药明康德的TIDES业务承接着上游制剂企业GLP-1药物委托生产。近年来，GLP-1药物在减肥领域的开 发成功，给提前布局的企业，如礼来、诺和诺德等带来了可观回报，同时吸引了众多药企布局开发。 GLP-1药物一度供不应求。 药明康德股价大涨：减肥药企业扩产 美国关税政策 对公司影响如何？ 药明康德（603259.SH、02359.HK）在最新发布的业绩报中预计，今年收入将重回增长，整体收入将达 到415亿至430亿元，将突破2023年在新冠商业化需求驱动下所形成的营收峰值。 3月18日上午，药明康德A股以及港股股价均高开，A股股价盘中涨停，港股股价盘中涨幅一度超过 13%。 摆在公司面前的是，上游减肥药企业扩产，美国关税政策、美国生物法案，这些对公司潜在影响如何？ 在3月18日上午的业绩电话会上，药明康德针对这些问题进行了回应。 近年来，药明康德TIDES（寡核苷酸和多肽）业务取代新冠项目，成为公司新的收入增长引擎之一，该 业务囊括了GLP-1等多肽药物生产。 根据药明康德发布的2 ...

来自美国客户收入250.2亿元，剔除新冠商业化项目同比增长7.7%；来自欧洲客户收入52.3亿元，同比增长14.4%；来自中国客户收入70.7亿元，同比下降3.5%；来自其他地区客户收入19. 公司预计2025年持续经营业务收入重回双位数增长，同比增长10%–15%，公司整体收入达到415–430亿元。公司将持续聚焦CRDMO核心业务，在新产能逐步投放的情况下，不断提高生产经营效 责任编辑：卢昱君 药明康德发布年度业绩母公司持有者应占溢利93.53亿元每股基本盈利3.24元 药明康德（02359）发布截至2024年12月31日止年度全年业绩，该集团期内取得收入392.41亿元（人民币，下同）；毛利160.16亿元；母公司持有者应占溢利93.53亿元；每股基本盈利3.2 公告称，公司为全球医药及生命科学行业提供一体化、端到端的新药研发和生产服务，在亚洲、欧洲、北美等地均设有运营基地。公司通过独特的"CRDMO"业务模式，不断降低研发门槛，助力客 2024年末，公司整体活跃客户约6000家。其中，持续经营业务截至年末活跃客户约5500家，持续经营业务全年新增客户约1000家，全球各地客户对公司服务的需求持续增长。 ...