证券代码：688136 证券简称：科兴制药 公告编号：2025-020 科兴生物制药股份有限公司 股票交易异常波动公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 科兴生物制药股份有限公司（以下简称"公司"）股票连续三个交易日 内（2025 年 4 月 10 日、4 月 11 日、4 月 14 日）收盘价格涨幅偏离值累计超过 30%，属于股票交易异常波动。 经公司自查，并向公司控股股东、实际控制人进行书面询证，截至本公 告披露日，确认不存在关于公司的应披露而未披露的重大事项，公司日常经营情 况正常，未发生重大变化，所处的行业政策未发生重大调整。 公司股价短期波动幅度较大，公司特别提醒广大投资者，注意投资风险、 理性决策、审慎投资。 一、股票交易异常波动的具体情况 公司股票连续三个交易日内（2025 年 4 月 10 日、4 月 11 日、4 月 14 日） 收盘价格涨幅偏离值累计超过 30%，根据《上海证券交易所科创板股票异常交易 实时监控细则》的有关规定，属于股票交易异常波动的情形。 二、公司关注并核实的 ...

特此回函! 关于《科兴生物制药股份有限公司股票交易异常波动询证函》的回函 8 实际控制人: 1225 科兴生物制药股份有限公司: 贵公司发出的《科兴生物制药股份有限公司股票交易异常波动询证函》已收 悉，经过认真自查，现就有关情况回复如下： 截至本函签署日,本人作为贵公司的实际控制人,不存在影响贵公司股票交 易异常波动的重大事项,不存在其他应披露而未披露的重大信息,包括但不限于 筹划并购重组、股份发行、债务重组、业务重组、资产剥离和资产注入等对贵公 司股票交易价格产生较大影响的重大事项。本人在贵公司本次股票交易异常波动 期间未买卖贵公司股票。 2025 年 4 月 14 日 ...

关于《科兴生物制药股份有限公司股票交易异常波动询证函》的回函 科兴生物制药股份有限公司: 贵公司发出的《科兴生物制药股份有限公司股票交易异常波动询证函》已收 悉,经过认真自查,现就有关情况回复如下: 深圳科益医药 202 一、截至目前,本企业不存在除在指定媒体上已公开披露的信息以外影响贵 公司股票交易价格异常波动的重大事宜; 二、截至目前,本企业不存在处于筹划阶段的涉及贵公司的重大事项,包括 但不限于重大资产重组、股份发行、上市公司收购、债务重组、业务重组、资产 剥离、资产注入等重大事项; 三、在本次股票交易异常波动期间,本企业不存在买卖贵公司股票的情形。 特此回函! ...

本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 会议召开时间：2025 年 04 月 23 日 （星期三） 15:00-17:00 会 议 召 开 地 点 ： 上 海 证 券 交 易 所 上 证 路 演 中 心 （ 网 址 ： https://roadshow.sseinfo.com/） 证券代码：688136 证券简称：科兴制药 公告编号：2025-021 科兴生物制药股份有限公司 关于参加 2024 年度科创板生物制品及 CXO 行业 集体业绩说明会的公告 会议召开方式：上证路演中心网络互动 投资者可于 2025 年 04 月 16 日（星期三）至 04 月 22 日（星期二）16:00 前登录上证路演中心网站首页点击"提问预征集"栏目或通过公司邮箱 ir@kexing.com 进行提问。公司将在说明会上对投资者普遍关注的问题进行回答。 科兴生物制药股份有限公司（以下简称"公司"）已于 2025 年 4 月 11 日发布 公司 2024 年度报告，为便于广大投资者更全面深入地了解公司 2024 年度经营成 ...

截至2025年4月14日 14:12，上证科创板综合指数(000680)上涨0.61%，成分股悦康药业(688658)上涨 19.91%，科兴制药(688136)上涨16.90%，华丰科技(688629)上涨11.72%，路德环境(688156)上涨8.36%， 南亚新材(688519)上涨8.04%。 数据显示，截至2025年3月31日，上证科创板综合指数(000680)前十大权重股分别为海光信息(688041)、 寒武纪(688256)、中芯国际(688981)、金山办公(688111)、中微公司(688012)、传音控股(688036)、联影 医疗(688271)、百利天恒(688506)、澜起科技(688008)、晶科能源(688223)，前十大权重股合计占比 22.34%。 科创综指ETF鹏华(589680)，场外联接A：023757；联接C：023758。 以上内容与数据，与界面有连云频道立场无关，不构成投资建议。据此操作，风险自担。 申万宏源证券指出，AI产业链持续突破——国产算力突围×物理智能革命×机器人量产元年，市场每次 回调都是筹码再沉淀。后续AI产业链催化节点或集中在5-6月，届时阿里、 ...

Core Viewpoint - The article discusses the recent performance of the STAR Market Composite Index and highlights the impact of U.S.-China trade policies on the pharmaceutical sector, suggesting potential investment opportunities in innovation, overseas markets, equipment upgrades, and consumer recovery [3][4]. Group 1: Market Performance - As of April 14, 2025, the STAR Market Composite Index rose by 1.13%, with notable increases in stocks such as Yuyuan Pharmaceutical (up 19.99%) and Kexing Pharmaceutical (up 17.23%) [3]. - The STAR Market ETF (Hua Xia) also saw a rise of 1.19%, marking its fifth consecutive increase, with a latest price of 0.94 yuan [3]. - The trading volume for the STAR Market ETF was active, with a turnover rate of 23.24% and a transaction value of 197 million yuan [3]. Group 2: Trade Policy Impact - Following the U.S. government's announcement of a 34% tariff on Chinese goods on April 2, 2025, both countries adjusted their bilateral trade tariffs to 125% as of April 11, 2025 [3]. - The frequent adjustments in tariff policies are expected to disrupt U.S.-China pharmaceutical trade, but companies primarily exporting to markets outside the U.S. may be less affected [3]. - The increased tariffs on U.S. goods could accelerate the import substitution process for high-market-share biopharmaceutical products in China [3]. Group 3: Investment Themes - The report suggests focusing on "innovation," "overseas expansion," "equipment upgrades," and "consumer recovery" as key investment themes [4]. - The "innovation" theme emphasizes investing in globally competitive innovative drugs and promising categories with significant market potential [4]. - The "overseas expansion" theme indicates that there are long-term opportunities in overseas markets [4]. - The "equipment upgrades" theme anticipates increased support for medical equipment updates from central and local government financing [4]. - The "consumer recovery" theme highlights potential rebounds in sectors like ophthalmology, dentistry, and medical aesthetics due to consumer stimulus policies [4]. Group 4: ETF Performance and Metrics - The STAR Market ETF (Hua Xia) has reached a new high in scale at 839 million yuan and a new high in shares at 908 million [4]. - Recent net inflows into the ETF totaled approximately 22.08 million yuan, with a total of 57.84 million yuan net inflow over the past five trading days [4]. - The ETF's management fee is 0.15%, and the custody fee is 0.05%, which are among the lowest in comparable funds [5]. - The tracking error for the ETF over the past month is 0.010%, indicating high tracking precision compared to similar funds [5]. Group 5: Valuation Insights - The latest price-to-earnings ratio (PE-TTM) for the STAR Market Composite Index is 129.12, which is at a historical low, being in the 19.67th percentile over the past year [6]. - The top ten weighted stocks in the STAR Market Composite Index account for 22.34% of the index, with companies like Haiguang Information and Cambricon Technologies among the leaders [6].

Investment Rating - The report maintains a "Recommendation" rating for Kexing Pharmaceutical (688136.SH) [3][10] Core Viewpoints - Kexing Pharmaceutical achieved a revenue of 1.407 billion yuan in 2024, representing an increase of 11.75%, and turned a profit with a net profit of 31 million yuan [4][7] - The company plans to distribute a cash dividend of 0.8 yuan per 10 shares to all shareholders [4] - The overseas sales revenue is expected to grow significantly, with a projected increase of 62% in 2024 [7] - The company is focusing on new emerging markets and has submitted over 120 registration applications for its products in more than 60 countries [7] - Kexing's innovative drug pipeline is progressing, with multiple projects in clinical trials, including two in Phase III [8] Summary by Sections Financial Performance - In 2024, Kexing Pharmaceutical reported a revenue of 1.407 billion yuan, up 11.75% from the previous year, and a net profit of 31 million yuan [4][7] - The company’s operating expenses showed a decrease in sales expense ratio by 12.33 percentage points to 42.42% [7] - The R&D expense ratio decreased by 15.45 percentage points to 11.94% due to reduced clinical and trial costs [7] Market Expansion - The company’s flagship product, albumin paclitaxel, received EU approval in July 2024, with increasing sales orders [7] - Kexing is targeting emerging markets, achieving over 15% sales growth in these regions during the reporting period [7] Innovation Pipeline - Kexing is advancing several projects in clinical trials, including GDF15 monoclonal antibody and dual-specific antibodies targeting VEGF/ANG-2 and IL-4R/IL-31 [8] - The GDF15 project is aimed at treating cancer cachexia and has received IND application acceptance from the Chinese regulatory authority [8] Future Projections - Revenue forecasts for 2025-2027 have been adjusted to 1.935 billion, 2.288 billion, and 2.807 billion yuan respectively [8] - Net profit projections for the same period are revised to 123 million, 243 million, and 357 million yuan respectively [8]

Key Points Summary of the Conference Call for Kexing Pharmaceutical Company Overview - Kexing Pharmaceutical reported a robust performance in 2024, achieving total revenue of 1.85 billion yuan, a year-on-year increase of 60% [4][3] - The company turned a profit with a net profit of 35 million yuan, and EBITDA of 204 million yuan, reflecting over 200% growth [4][3] Financial Performance - Total revenue for 2024 reached 1.4 billion yuan, with a 12% year-on-year growth [3] - Q4 revenue was 317 million yuan, up 27% year-on-year [3] - Overseas sales revenue was 220 million yuan, marking a 60% increase [3][4] - Operating cash flow turned positive, reaching 100 million yuan [4][3] Domestic Market Performance - Domestic sales revenue was 1.18 billion yuan, showing stable growth despite the impact of centralized procurement [5][4] - The company maintained a solid domestic market presence, indicating a stable foundation [5][4] Overseas Market Performance - Kexing's overseas sales grew by 60% in 2024, primarily driven by the sales of interleukin in the EU [6][4] - The company has introduced 16 new products and established branches in multiple regions to enhance marketing capabilities [6][4] Research and Development - R&D expenses remained high at approximately 1 billion yuan, with significant investment in Phase III clinical trials [7][4] - The company is focusing on innovative products based on antibody and protein technology platforms, including the GB05 project for RSV treatment, which has entered Phase III trials [7][4] Future Development Strategy - Kexing aims to focus on protein antibodies and delivery technology innovations over the next five years, planning to establish subsidiaries for collagen, trillion replacements, and anti-tumor products [10][4] - The company targets achieving 6 NDAs and 15 INDs within five years, aspiring to become a high-quality drug export platform covering over 70 countries [10][4] Equity Incentive Plan - Kexing launched a second equity incentive plan in 2024, targeting a sales growth of 200%-400% for 2025, with a minimum sales goal of 60 million USD [9][4] Commercialization and Product Pipeline - The company has formed a trend of "introducing, launching, and scaling" its products, with expectations of reaching a minimum overseas sales peak of 1.5 billion yuan by 2026 or 2027 [12][4] - Kexing is focusing on antibody and protein drug development in oncology and autoimmune fields, emphasizing the Kexing body platform [17][4] Regulatory and Market Expansion - Kexing has established a German subsidiary to enhance its presence in the EU market, with plans to introduce 10 to 20 products focusing on oncology, autoimmune, and metabolic diseases [31][4] - The company is actively researching market demands and competition in Europe to quickly collaborate with domestic partners for product launches [31][4] Conclusion - Kexing Pharmaceutical is committed to innovation and internationalization, with clear strategic goals for the coming years, aiming to enhance its quality and market position [33][4]

医药 2025 年 04 月 14 日 科兴制药(688136.SH) 24年利润端实现扭亏，关注新品海外放量节奏 推荐（维持） 股价：30.00 元 主要数据 | 行业 | 医药 | | --- | --- | | 公司网址 | www.kexing.com | | 大股东/持股 | 深圳科益医药控股有限公司/66.01% | | 实际控制人 | 邓学勤 | | 总股本(百万股) | 200 | | 流通 A 股(百万股) | 200 | | 流通 B/H 股(百万股) | | | 总市值（亿元） | 60 | | 流通 A 股市值(亿元) | 60 | | 每股净资产(元) | 8.19 | | 资产负债率(%) | 48.2 | | 行情走势图 | | 相关研究报告 【平安证券】科兴制药（688136.SH ）*公司动态跟踪 报告*出海业务有望保持高增长，创新药平台价值静待 重估*推荐20250402 证券分析师 | 叶寅 | 投资咨询资格编号 | | --- | --- | | | S1060514100001 | | | BOT335 | | | YEYIN757@pingan.com.cn | | ...

Core Viewpoint - The report highlights the significant growth and strategic advancements of Sinovac Biotech in 2024, emphasizing its dual strategy of "innovation + internationalization" amidst increasing competition in the global pharmaceutical industry [1][5]. Financial Performance - In 2024, Sinovac Biotech achieved a revenue of 1.407 billion yuan, representing a year-on-year growth of 11.75% [1]. - The net profit attributable to shareholders was 31.48 million yuan, with a net profit of 35.25 million yuan after excluding non-recurring gains and losses [1]. R&D Innovation - Sinovac Biotech has transitioned to innovative drug development, with 14 projects in the pipeline, including 4 in clinical stages, focusing on antiviral, oncology, and autoimmune diseases [2]. - The GB18 project, targeting GDF-15 for cancer cachexia treatment, has completed international patent registration and shows promising preclinical data [2]. - The company is leveraging AI and computer-aided drug design (CADD) to enhance antibody molecule design and optimize drug efficacy [2][3]. International Expansion - Overseas revenue surpassed 200 million yuan in 2024, increasing its share of total revenue from 11% in 2023 to 16% [5]. - Sinovac Biotech has shifted from simple product exports to platform-based international collaborations, achieving over 15% sales growth in emerging markets [5]. - The approval of albumin-bound paclitaxel in the EU marks a significant milestone for the company, being the first domestic product to gain such approval [5]. Strategic Advantages - The company emphasizes speed in its international collaboration process, with the ability to submit product registration documents within a month of signing agreements [6]. - Sinovac Biotech provides comprehensive services in market insights, marketing, and risk management to empower its partners [6][7].