Summary of Hualan Biological's Conference Call Company Overview - **Company**: Hualan Biological - **Industry**: Biological Products, Blood Products, Vaccines Key Financial Performance - **2024 Total Revenue**: 2.09 billion CNY, down 18.79% YoY - **2024 Net Profit**: 1.088 billion CNY, down 26.57% YoY - **Q1 2025 Revenue**: 868 million CNY, up 10.2% YoY - **Q1 2025 Net Profit**: 313 million CNY, up 19.62% YoY, indicating signs of recovery [1][2][27] Revenue Breakdown - **Blood Products Revenue (2024)**: 3.25 billion CNY, up 10.9 million CNY YoY - **Vaccine Revenue (2024)**: 1.128 billion CNY, down 53.21% YoY - **Q1 2025 Blood Products Revenue**: 813 million CNY, up 11.98% YoY - **Q1 2025 Vaccine Revenue**: 24 million CNY, down 29.05% YoY [2][8] Plasma Collection and Industry Position - **2024 Plasma Collection**: 1,586 tons, up 18.18% YoY, exceeding industry average growth of 10% - **New Plasma Stations**: Expansion through existing and new stations, with plans for more in traditional regions like Henan and Chongqing [1][5][22] Product Pricing and Inventory - **Price Trends**: Human albumin prices decreased from 420 CNY to 360-380 CNY; immunoglobulin prices dropped from 700 CNY to 550-560 CNY - **Inventory Levels**: Company maintains reasonable inventory levels, with a smaller increase compared to industry peers [6][7][23] New Product Developments - **Biosimilar Sales**: Expected to exceed 100 million CNY in 2025, with a dedicated sales team established - **Upcoming Products**: Bevacizumab launched, with Rituximab application submitted; 1-3 new products expected in the next three years [1][9][10] Market Outlook - **Vaccination Rates**: Optimistic about flu vaccine uptake, anticipating significant growth in sales and profits [1][27] - **Future Growth**: Anticipated annual plasma collection growth of 10%, driven by aging population and demand [20] Strategic Initiatives - **New Factory**: Expected to start production in 2026, with minimal financial pressure from depreciation [3][17] - **Sales Strategy**: Focus on maintaining stable pricing and leveraging brand quality to sustain market position [19][23] Conclusion - **Overall Growth Expectation**: Hualan Biological is positioned for recovery and growth across blood products, vaccines, and monoclonal antibodies, with a collaborative approach to enhance overall performance [28]

Core Viewpoint - The blood products industry is experiencing a significant divergence in performance among companies, with some reporting growth while others face declines in revenue and profit [1][2]. Group 1: Company Performance in 2024 - Shanghai Laisai (002252) and Tiantan Biological (600161) reported revenue growth of 2.67% and 16.44% respectively, with net profits increasing by 23.25% and 39.58% [1]. - Hualan Biological (002007), Boya Biological (300294), and Bohui Innovation (300318) experienced revenue declines of 18.02%, 34.58%, and 18.53% respectively, while Hualan's net profit fell by 26.57% [1]. - Bohui Innovation managed to turn a profit with a net profit of 0.09 billion yuan, compared to a loss in the previous year [1]. Group 2: Q1 2025 Performance - In Q1 2025, Tiantan Biological, Hualan Biological, and Boya Biological continued to show revenue growth, while Shanghai Laisai, Tiantan Biological, and Paillin Biological saw revenue declines of 2.45%, 0.57%, and 14% respectively [1]. - Hualan Biological's net profit increased by 19.62%, while Shanghai Laisai and Tiantan Biological reported net profit declines of 25.2% and 22.9% respectively [1]. - The decline in profits for Tiantan Biological was attributed to a decrease in product prices that outweighed the benefits of increased sales volume [1]. Group 3: Market Dynamics - The blood products market is expected to maintain stable growth in 2024, with significant competition in the human albumin market due to increased imports [2][3]. - The cancellation of certain medical insurance restrictions is expected to release market demand for coagulation factor products, contributing to their growth [2]. - The overall price trend for blood products is declining, influenced by increased competition and supply exceeding demand for certain products [3]. Group 4: Industry Consolidation - The blood products industry is characterized by high entry barriers, with fewer than 30 companies currently operating due to strict regulations on blood product production [6][7]. - Recent mergers and acquisitions are expected to enhance industry concentration, with leading companies gaining competitive advantages through resource acquisition [6][7]. - Companies like Tiantan Biological and Shanghai Laisai have made significant acquisitions to expand their production capabilities and market presence [7]. Group 5: Market Size and Growth Projections - The blood products market in China reached a scale of 600 billion yuan in 2024, with projections to grow to 780 billion yuan by 2027, reflecting a compound annual growth rate of 11.6% from 2022 to 2027 [8].

Core Viewpoint - The company, Hualan Biological Engineering Inc., has released its first quarter report for 2025, ensuring the accuracy and completeness of the financial information disclosed, with no significant omissions or misleading statements [1][2]. Financial Data Summary - The first quarter report has not been audited [3][7]. - The company does not require retrospective adjustments or restatements of previous accounting data [3]. - Non-recurring gains and losses include a refund of handling fees [3]. - The company confirms that there are no instances of classifying non-recurring gains and losses as recurring [3]. Shareholder Information - As of the reporting period, the total number of ordinary shareholders is not disclosed, but the company holds 6,027,467 shares in a repurchase account, representing 1.00% of total shares, ranking fifth among the top ten shareholders [5].

Group 1: Company Performance - In Q1, Hualan Biological achieved revenue of 868 million yuan, a year-on-year increase of 10.2% [1] - The net profit attributable to shareholders was 313 million yuan, up 19.62% year-on-year, while the net profit excluding non-recurring gains and losses was 300 million yuan, increasing by 35.35% [1] - The blood products segment generated revenue of 843 million yuan, with a year-on-year growth of 11.98% and a net profit of 291 million yuan, reflecting a 23.47% increase [1] Group 2: Vaccine Business - Hualan Vaccine reported Q1 revenue of 24.28 million yuan, a decline of 29.05% year-on-year, with a net profit of 32.78 million yuan, down 15.06% [2] - The net profit excluding non-recurring gains and losses was 15.42 million yuan, showing an increase of 8.89% [2] - The company anticipates that vaccine sales will improve in Q2 as product approvals and sales efforts ramp up [2] Group 3: Industry Trends - The plasma collection volume for Hualan Biological reached a record high of 1586.37 tons in 2024, marking an 18.18% increase [3] - The blood products industry is experiencing increased merger and acquisition activities, with plasma stations becoming a strategic focus for companies [3] - Notable acquisitions include Boya Biological's purchase of 100% of Green Cross China for 1.82 billion yuan, adding 4 plasma stations, and Tian Tan Biological's acquisition of 5 plasma stations from CSL Asia Pacific [3]

Core Viewpoint - Hualan Biological's Q1 2025 financial report shows strong growth driven by its "blood products + vaccines + recombinant protein drugs" strategy, with significant increases in revenue and net profit compared to the previous year [1][2]. Financial Performance - The company achieved a revenue of 868 million yuan, a year-on-year increase of 10.2% [1]. - The net profit attributable to shareholders was 313 million yuan, reflecting a growth of 19.62% year-on-year [1]. - The non-recurring net profit reached 300 million yuan, up 35.35% from the same period last year [1]. - Blood products business generated revenue of 843 million yuan, a growth of 11.98% year-on-year, with a net profit of 291 million yuan, increasing by 23.47% [1]. Product Performance - Hualan Biological maintains a leading market share in domestic blood products, with core product batch approvals remaining among the top in the industry [2]. - The vaccine segment is expected to see growth in Q2 as flu vaccine sales ramp up following seasonal factors [2]. - The new product Bevacizumab began sales in Q1 2025, with expectations for increased sales in Q2, potentially creating a new growth driver [2]. Research and Development - The company invested 66.46 million yuan in R&D, accounting for 7.66% of its revenue, indicating a commitment to biopharmaceutical innovation [2]. - Hualan Biological's plasma collection efforts have led to a record high collection volume of 1586.37 tons in 2024, an increase of 18.18% year-on-year [2]. Strategic Outlook - The Q1 performance validates the effectiveness of the company's three-pronged strategy and demonstrates resilience and robust growth in core business areas [2]. - Future growth is anticipated as domestic vaccine demand recovers and the blood products industry consolidates, with Bevacizumab expected to capture a larger market share in a market projected to reach hundreds of billions [2].

本公司及董事会全体成员保证信息披露的内容真实、准确和完整，没有虚假记载、误导性陈述或重大遗 漏。 特别提示： 1.本次股东大会未出现否决议案的情形。 登录新浪财经APP 搜索【信披】查看更多考评等级 2.本次股东大会不涉及变更以往股东大会已通过的决议。 一、会议召开和出席情况 1、本次股东大会的召开时间： 现场会议召开时间为：2025年4月25日下午13:00 网络投票时间：2025年4月25日。其中通过深圳证券交易所交易系统进行网络投票的具体时间为2025年4 月25日上午9:15一9:25,9:30一11:30和下午13:00一15:00；通过深圳证券交易所互联网投票的具体时间为 2025年4月25日9:15至15:00期间的任意时间。 2、会议召开地点：华兰生物疫苗股份有限公司（以下简称"公司"）办公楼会议室 3、召集人：公司董事会 4、会议方式：现场投票、网络投票相结合的方式 5、现场会议主持人：董事长安康先生 6、本次股东大会的会议召集、召开程序符合有关法律、法规、规范性文件及《公司章程》的有关规 定。 7、会议出席情况： 公司有表决权股份总数为595,000,033股。 股东出席的总体情况： 通过 ...

Financial Performance - The company's revenue for Q1 2025 reached ¥867,612,696.57, representing a 10.20% increase compared to ¥787,309,418.97 in the same period last year[5] - Net profit attributable to shareholders was ¥313,135,984.76, up 19.62% from ¥261,773,937.60 year-on-year[5] - The net profit excluding non-recurring gains and losses increased by 35.35%, amounting to ¥299,741,568.52 compared to ¥221,458,779.28 in the previous year[5] - Total operating profit increased to ¥397,453,634.36, up from ¥331,130,131.08, representing a growth of approximately 19.98% year-over-year[19] - Net profit attributable to the parent company reached ¥313,135,984.76, compared to ¥261,773,937.60 in the previous period, marking an increase of about 19.58%[20] - Basic earnings per share rose to ¥0.1715 from ¥0.1431, reflecting a growth of approximately 19.88%[20] - The company’s total profit amounted to ¥384,573,318.12, compared to ¥328,375,091.95 in the previous period, showing an increase of approximately 17.14%[19] Cash Flow - The net cash flow from operating activities decreased significantly by 71.75%, totaling ¥14,178,581.71, down from ¥50,186,473.40 in the same period last year[5] - Cash flow from operating activities generated a net cash inflow of ¥14,178,581.71, down from ¥50,186,473.40, indicating a decline of about 71.73%[22] - Cash flow from investing activities resulted in a net outflow of ¥356,667,079.56, compared to a smaller outflow of ¥64,142,690.50 in the previous period[22] Assets and Liabilities - Total assets at the end of the reporting period were ¥16,638,920,951.35, reflecting a 2.02% increase from ¥16,309,951,355.29 at the end of the previous year[5] - Current assets totaled ¥10,549,823,747.89, up from ¥9,616,191,068.19 at the beginning of the period, reflecting a growth of about 9.7%[15] - Total liabilities amounted to ¥2,466,351,246.39, slightly up from ¥2,463,225,371.87, showing a marginal increase[16] - Total assets reached ¥16,638,920,951.35, compared to ¥16,309,951,355.29 at the beginning of the period, reflecting an increase of about 2.0%[16] - The equity attributable to the parent company increased to ¥12,172,136,621.05 from ¥11,858,784,465.45, a growth of approximately 2.6%[16] Shareholder Information - The number of ordinary shareholders at the end of the reporting period was 146,328[11] - The largest shareholder, Ankang, holds 17.92% of the shares, amounting to 327,787,406 shares[11] - The company has not reported any significant changes in the top 10 shareholders or their participation in margin trading activities[12] Expenses - The company reported a significant increase in financial expenses by 112.69%, primarily due to a decrease in interest income[9] - Total operating costs increased to ¥553,612,323.28 from ¥544,582,536.78, reflecting a rise of about 1.89%[19] - Research and development expenses were ¥66,459,646.88, down from ¥72,713,577.15, indicating a decrease of approximately 8.66%[19] - The company reported investment income of ¥38,443,296.73, an increase from ¥34,260,128.01, representing a growth of about 6.38%[19] Cash and Receivables - Cash and cash equivalents decreased to ¥1,102,190,831.95 from ¥1,366,659,508.49, a decline of approximately 19.4%[14] - Trade receivables increased to ¥1,870,813,379.20 from ¥1,798,428,848.41, representing a growth of about 4.0%[15] - Inventory rose to ¥2,231,831,545.80 from ¥2,028,565,707.69, indicating an increase of approximately 10.0%[15] - Cash and cash equivalents at the end of the period decreased to ¥1,096,939,137.47 from ¥1,168,607,650.23, a decline of approximately 6.13%[23]

证券代码：002007 证券简称：华兰生物 公告编号：2025-015 华兰生物工程股份有限公司 2024年度股东大会决议公告 本公司及董事会全体成员保证信息披露的内容真实、准确和完整，没有虚假 记载、误导性陈述或重大遗漏。 特别提示： 1、本次股东大会未出现否决议案的情形； 2、本次股东大会不涉及变更前次股东大会决议的情形。 一、会议召开和出席情况 1、本次股东大会的召开时间： 现场会议召开时间为：2025年4月25日下午14:30 网络投票时间：2025年4月25日。其中通过深圳证券交易所交易系统进行网络 投票的具体时间为2025年4月25日上午9:15—9:25,9:30—11:30和下午13:00— 15:00；通过深圳证券交易所互联网投票的具体时间为2025年4月25日09:15至15:00 期间的任意时间。 2、会议召开地点：公司办公楼会议室 3、会议方式：现场投票、网络投票相结合的方式 4、召集人：公司董事会 5、现场会议主持人：董事长安康先生 6、本次股东大会的会议召集、召开程序符合有关法律、法规、规范性文件及《公 司章程》的有关规定。 7、会议出席情况： （1）出席会议总体情况 出席本次股东 ...

安徽承义律师事务所 关于 华兰生物工程股份有限公司 召开 2024 年度股东大会的 法律意见书 安徽承义律师事务所 中国.合肥市政务区怀宁路 200 号栢悦中心 5 楼 邮编: 230022 电话（Tel）: （86-551）65609815 传真（Fax）: （86-551）65608051 网址（Website）: www.chengyi-law.com 电子信箱（E-mail）：chengyilawyer@163.com 安徽承义律师事务所 关于华兰生物工程股份有限公司 召开 2024 年度股东大会的法律意见书 （2025）承义法字第 00071 号 致：华兰生物工程股份有限公司 根据《中华人民共和国公司法》《中华人民共和国证券法》《上市公司股东 会规则》等法律法规和其他规范性文件的要求，安徽承义律师事务所接受华兰生 物工程股份有限公司（以下简称"公司"）的委托，指派束晓俊、万晓宇律师（以 下简称"本律师"）就公司召开 2024 年度股东大会（以下简称"本次股东大会"） 出具法律意见书。 一、本次股东大会召集人资格和召集、召开的程序 经核查，本次股东大会是由公司第八届董事会召集，公司已于 2025 年 ...

登录新浪财经APP 搜索【信披】查看更多考评等级 证券代码：301207 证券简称：华兰疫苗公告编号：2025-022 华兰生物疫苗股份有限公司 关于召开2024年度股东大会的提示性公告 本公司及董事会全体成员保证信息披露的内容真实、准确和完整，没有虚假记载、误导性陈述或重大遗 漏。 华兰生物疫苗股份有限公司（以下简称"公司"）已于2025年3月29日在《证券时报》、《中国证券 报》、《上海证券报》及巨潮资讯网（www.cninfo.com.cn）披露了《关于召开2024年度股东大会的通 知》（公告编号：2025-020）。本次股东大会采取现场投票和网络投票相结合的表决方式召开，根据有 关规定，现将股东大会的相关事项再次提示如下： 一、召开会议的基本情况 1、股东大会届次：2024年度股东大会； 2、股东大会召集人：公司董事会； 3、会议召开的合法、合规性：本次股东大会会议的召开符合有关法律、行政法规、部门规章、规范性 文件和公司章程的规定。 4、会议召开方式：现场投票+网络投票 （1）现场投票：股东本人出席现场会议或者通过授权委托书（附件二）委托他人出席现场会议； （2）网络投票：本次股东大会通过深圳证券交 ...