Guardant Health (NASDAQ:GH) has received approval from the U.S. FDA for its Guardant360 CDx, which serves as a companion diagnostic tool. The Guardant360 CDx is specifically approved for use alongside Inluriyo, developed by Eli Lilly (LLY), in treating adults ...

After a multi-year run, sentiment around Eli Lilly (NYSE: LLY ) and the broader sector has deteriorated. This has resulted in steep underperformance relative to the market, driven by the market waiting for more clarityI am currently studying economics and accounting at UCSB, and interning at a UBS wealth management office. I am seeking a career in equity research, and I became passionate about equities through managing a stock portfolio of companies that I track closely.Analyst’s Disclosure:I/we have a bene ...

After a multi-year run, sentiment around Eli Lilly (NYSE: LLY ) and the broader sector has deteriorated. This has resulted in steep underperformance relative to the market, driven by the market waiting for more clarityI am currently studying economics and accounting at UCSB, and interning at a UBS wealth management office. I am seeking a career in equity research, and I became passionate about equities through managing a stock portfolio of companies that I track closely.Analyst’s Disclosure:I/we have a bene ...

Group 1 - Investors are showing a bullish stance on Eli Lilly (NYSE: LLY), with significant options trades indicating potential insider knowledge of upcoming events [1][2] - The overall sentiment among large investors is split, with 34% bullish and 34% bearish, highlighting mixed expectations [2] - Notable options activity includes 15 call options totaling $1,103,597 and 8 put options totaling $646,055, suggesting a cautious approach among traders [2] Group 2 - Whales have targeted a price range for Eli Lilly between $640.0 and $850.0 over the last three months, indicating a focused investment strategy [3] - The mean open interest for Eli Lilly options trades is 754.85, with a total volume of 802.00, reflecting active trading interest [4] Group 3 - Eli Lilly's key products span various therapeutic areas, including neuroscience, cardiometabolic, cancer, and immunology, with notable drugs like Verzenio and Mounjaro [11] - Recent analyst opinions show a range of price targets, with an average target of $940.0, while one analyst lowered their rating to Hold with a target of $830, and another maintained an Overweight rating with a target of $1050 [12][13] Group 4 - The current stock price of Eli Lilly is $718.34, down 0.86%, with upcoming earnings expected in 30 days [15]

HOUSTON, TEXAS - SEPTEMBER 23: Eli Lilly CEO David A. Ricks speaks at a press conference at Generation Park in Houston, Monday, Sept. 23, 2025. (Raquel Natalicchio/Houston Chronicle via Getty Images)Houston Chronicle via Getty ImagesEli Lilly stock (NYSE: LLY) should be on your radar. Here’s why – it is presently trading within the support range ($688 – $761), price points from which it has previously bounced significantly. Over the past 10 years, the stock has attracted buying interest at this level 5 time ...

Core Insights - The article discusses the performance of value stocks, particularly those that pay dividends, highlighting their historical outperformance compared to growth stocks [2][4]. Value Stocks Performance - Value stocks, defined by low price-to-book ratios, have outperformed growth stocks by an average of 2.5% annually since 1926 [2]. - The trend of value stocks outperforming growth stocks was disrupted during the global financial crisis from 2007 to 2020, but value stocks regained some traction in 2020 before losing ground again in late 2022 [2]. Investment Strategy - Joseph H. Davis from Vanguard emphasizes the importance of broad diversification and focusing on undervalued stocks to mitigate risks associated with market transformations, such as those driven by artificial intelligence [3]. Methodology for Stock Selection - The article utilizes Insider Monkey's Q2 2025 database to identify dividend stocks with forward P/E ratios below 25 as of September 26, ranking them based on hedge fund interest [6]. Company Highlights - **Eli Lilly and Company (NYSE: LLY)** - Forward P/E as of September 26: 23.70 - Major revenue drivers include Mounjaro, Zepbound, and Verzenio, which contributed to 65% of Q2 revenue of $15.6 billion, with growth rates between 12% and 172% [9]. - R&D expenses increased by 23% year-over-year to $3.3 billion, representing over 21% of revenue [10]. - The company has raised dividends for 11 consecutive years, currently offering $1.50 per share with a yield of 0.83% [11]. - **Abbott Laboratories (NYSE: ABT)** - Forward P/E as of September 26: 23.42 - Declared a quarterly dividend of $0.59 per share, maintaining a 53-year streak of dividend increases, with a yield of 1.77% [13]. - The FreeStyle Libre glucose monitoring system has become a significant growth driver despite a decline in COVID-19 test sales [14]. - **Illinois Tool Works Inc. (NYSE: ITW)** - Forward P/E as of September 26: 22.47 - Focuses on efficiency and customer-driven innovation, with a strategy that emphasizes operational improvements and disciplined portfolio management [15][16]. - Announced a 7.3% increase in its quarterly dividend to $1.61 per share, extending its dividend growth streak to 53 years, with a yield of 2.47% [17].

The blockbuster medications could open a new frontier for the pharma giants. ...

ab 23 September 2025 Global Research Global Pharmaceuticals Framing Global GLP-1 forecasts to 2030 UBS forecast $130bn GLP-1 sales in 2030 Over the last 12 months, the outlook for the GLP-1 market for both obesity and type-2 diabetes (T2D) has weakened driven by the disruption from compounded product in the US market and from weaker than expected data from next generation assets (CagriSema and orforglipron). This has seen UBS 2030 global forecasts cut from > $150bn to $130bn, which assumes c.$80bn sales for ...

Core Insights - Eli Lilly has shown strong performance in the GLP-1 market, with significant commercial success from its products, particularly tirzepatide [1][10] - The company is on the verge of launching an oral GLP-1 medication, orforglipron, which has demonstrated superior efficacy in clinical trials compared to existing treatments [7][8] - Financial results indicate robust growth, with a 38% year-over-year revenue increase in Q2, reaching $15.6 billion, and a 61% rise in adjusted net earnings per share to $6.31 [10] Group 1: Product Development - Eli Lilly's tirzepatide, marketed as Mounjaro and Zepbound, is generating billions in sales but is administered via injection, which has drawbacks compared to oral medications [3][4] - The company is developing orforglipron, which has shown a 1.9% average blood-sugar reduction and 8.2% weight loss in trials, outperforming Novo Nordisk's Rybelsus [7][8] - If orforglipron receives regulatory approval by year-end, it could significantly boost Eli Lilly's stock value [8][9] Group 2: Financial Performance - Eli Lilly's revenue and earnings growth outpace industry averages, with a forward P/E ratio of 24.7 compared to the healthcare industry's 16.5 [10][11] - Analysts project orforglipron could generate $12.7 billion in revenue by 2030, while tirzepatide is expected to reach nearly $62 billion in revenue by the same year [12][13] - The company has additional products in the pipeline, such as Kisunla for Alzheimer's and Ebglyss for eczema, which could also contribute to future growth [14] Group 3: Market Outlook - Eli Lilly's strong clinical data and market position suggest continued growth in the GLP-1 sector, with expectations for market-beating returns over the next five years [15]

Core Viewpoint - Eli Lilly has terminated a Phase 2b obesity trial for bimagrumab, which was intended to evaluate its efficacy both as a monotherapy and in combination with its main GLP-1/GIP drug, tirzepatide, before any participants were recruited [4][6]. Summary by Sections Trial Termination - The trial was initially planned to recruit 180 adults with obesity or overweight and type 2 diabetes, but was halted due to strategic business reasons [4]. - The status of the trial changed from "not yet recruiting" to "withdrawn," indicating a significant shift in the company's research strategy [6]. Ongoing Research - Despite the termination of the trial, bimagrumab is still being studied in another ongoing Phase 2 trial, which evaluates its efficacy alone or in combination with tirzepatide in the obese population, with results expected in 2026 [6]. Comparative Study Results - A related Phase 2 study presented at the American Diabetes Association meeting showed that patients receiving a combination of bimagrumab and semaglutide (Novo Nordisk's GLP-1 drug) had a significantly higher percentage of fat loss compared to those on semaglutide alone, with over 90% of weight loss in the combination group coming from fat [6].