智通财经4月29日电，辉瑞公司重申2025年全年财务指引的所有组成部分，包括610亿美元至640亿美元 的收入和2.80美元至3.00美元的调整后摊薄后每股收益。 ...

Group 1 - Pfizer Inc. is set to release its Q1 earnings results on April 29, with expected earnings of 68 cents per share, a decrease from 82 cents per share in the same period last year [1] - The projected quarterly revenue for Pfizer is $14.09 billion, down from $14.88 billion a year earlier [1] - Guardant Health announced a strategic collaboration with Pfizer to enhance the development and commercialization of Pfizer's oncology portfolio using the Guardant Infinity smart liquid biopsy platform [2] Group 2 - UBS analyst Trung Huynh maintained a Neutral rating on Pfizer and reduced the price target from $28 to $24 [7] - Goldman Sachs analyst Asad Haider downgraded Pfizer from Buy to Neutral, cutting the price target from $32 to $25 [7] - Guggenheim analyst Vamil Divan reiterated a Buy rating for Pfizer, indicating a positive outlook [7]

Industry Overview - The first-quarter earnings season for the drug and biotech sector is underway, with major companies like Pfizer, Eli Lilly, Amgen, Biogen, and Regeneron set to announce results [1] - Johnson & Johnson and Merck have reported results, both exceeding first-quarter estimates for earnings and sales, while Sanofi had mixed results, beating earnings estimates but missing sales [1] Earnings Trends - As of April 23, 15% of companies in the Medical sector, representing 33.8% of the sector's market capitalization, reported quarterly earnings, with 77.8% surpassing estimates for both earnings and revenues [3] - Year-over-year earnings increased by 4.7%, and revenues rose by 9.4% [3] - Overall, first-quarter earnings for the Medical sector are expected to increase by 35%, while sales are projected to rise by 7.8% compared to the previous year [3] Company Performance Pfizer (PFE) - Pfizer has consistently exceeded earnings expectations in the last four quarters, with an average earnings surprise of 44.16% [5] - The Zacks Consensus Estimate for first-quarter sales and earnings is $13.88 billion and 64 cents per share, respectively [6] - Non-COVID operational revenues are driving growth, supported by products like Vyndaqel, Padcev, and Eliquis, despite a decline in sales of COVID products [7] Eli Lilly (LLY) - Eli Lilly has had mixed performance, exceeding earnings expectations in three of the last four quarters, with an average earnings surprise of 8.47% [8] - The Zacks Consensus Estimate for sales and earnings is $12.62 billion and $3.52 per share, respectively [8] - Growth is expected to be driven by demand for FDA-approved tirzepatide medicines, although sales of Mounjaro and Zepbound were below expectations [9][10] Amgen (AMGN) - Amgen has shown strong performance, beating earnings estimates in each of the last four quarters, with an average earnings surprise of 5.23% [11] - The Zacks Consensus Estimate for first-quarter sales and earnings is $7.96 billion and $4.15 per share, respectively [11] - Product sales are expected to be driven by strong volume growth, although prices may decline due to higher rebates [12] Biogen (BIIB) - Biogen has consistently beaten earnings estimates in the last four quarters, with an average earnings surprise of 11.80% [13] - The Zacks Consensus Estimate for sales and earnings is $2.23 billion and $3.52 per share, respectively [13] - Lower sales of multiple sclerosis drugs are likely to be offset by revenues from new drugs [14] Regeneron (REGN) - Regeneron has had mixed results, surpassing earnings expectations in three of the last four quarters, with an average earnings surprise of 3.23% [16] - The Zacks Consensus Estimate for first-quarter sales and earnings is $3.28 billion and $8.43 per share, respectively [17] - Sales of Eylea are expected to have declined due to competition, but sales of Eylea HD and Dupixent are likely to have surged [18][19]

Market Overview - US stock index futures are all down before the market opens, with Dow futures down 0.06%, S&P 500 futures down 0.12%, and Nasdaq futures down 0.07% [1] - Major European indices show positive performance, with Germany's DAX up 0.52%, UK's FTSE 100 up 0.11%, France's CAC40 up 0.72%, and the Euro Stoxx 50 up 0.50% [2][3] - WTI crude oil is down 0.33% at $62.81 per barrel, while Brent crude oil is down 0.36% at $65.56 per barrel [3][4] Economic Data and Corporate Earnings - The upcoming week is significant for economic data and corporate earnings, with the April non-farm payroll report and Q1 inflation data being key focuses [5] - 180 S&P 500 companies are set to report quarterly earnings, with major companies like Apple, Amazon, Coca-Cola, Eli Lilly, Meta, Microsoft, and Chevron in the spotlight [5] Corporate Actions - Spirit AeroSystems has reached an agreement with Airbus for the acquisition of certain assets, with Boeing repurchasing its previously divested business for $4.7 billion in stock [8] - Merck has announced a $3.9 billion acquisition of SpringWorks Therapeutics to enhance its oncology drug portfolio, with the deal valued at approximately $3.4 billion in enterprise value [9] - Amazon has seen prices of nearly 1,000 products rise by an average of 30% due to the impact of tariffs, affecting various categories from electronics to clothing [10] Earnings Forecast - Upcoming earnings reports include companies such as NXP Semiconductors, AstraZeneca, BP, Novartis, Deutsche Bank, HSBC, Coca-Cola, Pfizer, UPS, General Motors, Daqo New Energy, and JinkoSolar [11]

Regulatory Developments - The National Health Commission and other departments have released the 2025 National Random Supervision and Inspection Plan, which includes new regulatory areas such as internet diagnosis and treatment, and mental health, while explicitly targeting online medical fraud [1] - The regulatory focus on combating online medical fraud represents a significant upgrade in medical supervision, aiming to purify the medical online space [1] Pharmaceutical Approvals - Innovent Biologics announced that its third-generation EGFR TKI drug, Olitinib (Leratinib), has received approval from the National Medical Products Administration (NMPA) for first-line treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with specific EGFR mutations [2] - Olitinib is the only approved third-generation EGFR TKI based on a naphthalene structure, expanding treatment options for EGFR mutation-positive NSCLC patients [2] Market Regulation and Antitrust Issues - Xianju Pharmaceutical is facing a potential fine of approximately 195 million yuan for alleged monopolistic practices related to the pricing of dexamethasone phosphate raw materials, with the case still under review by the Tianjin Market Supervision Administration [3] - This incident highlights the regulatory authorities' emphasis on antitrust measures within the pharmaceutical industry, which could disrupt normal market operations [3] Combination Therapy Approvals - Pfizer announced that its oral targeted drug, Axi-cabtagene ciloleucel (Axitinib), has been approved for first-line treatment in combination with Toripalimab for high-risk, unresectable, or metastatic renal cell carcinoma (RCC) patients [4] - This approval marks the first and only approved first-line targeted and immune combination therapy for advanced kidney cancer in China, indicating a shift towards combination therapies in the treatment landscape [4]

见闻历 . 每天多看我一眼，投资赚的多一点。 | 见闻财经日历 | | | ▼ 华尔街见闻 | | --- | --- | --- | --- | | WSCN Economic Calendar | | | | | 时间 | 地区 | 内容 | 预期 前値 | | 4月28日 周一 | | | | | 事件 | 国内 | 待定 十四届全国人大常委会第十五次会议4月27日至 30日在北京举行 | | | 酒外 | | 待定 加拿大大选正式投票日 | | | 国内 | | 海天味业、昆仑万维、传音控股、药明康德、青岛啤酒 京东方A、上海电气、迈瑞医疗、恒立液压、保利发展 | | | | | 中国石化、张小泉、中国建筑、顺丰控股、宁沪高速 | | | 财报 | | 老板电器、百济神州-U、华帝股份 | | | 滝外 | | 达美乐披萨、恩智浦 | | | 4月29日 周二 | | | | | 事件 | 酒外 | 待定 日本股市因昭和日休市一日 | | | 滝 | | Meta首届开源Al大会 | | | 财报 | 国内 | 光明乳业、工商银行、海尔智家、贵州茅台 万科A、长江电力、通威股份、伊利股份、金龙鱼 韦尔 ...

Group 1 - Pfizer is expected to release its Q1 earnings soon, presenting a potential investment opportunity with a 7.55% dividend yield [1] - The dividend is considered highly likely to be safe due to Pfizer's stabilizing revenue trajectory [1] Group 2 - The article emphasizes the importance of thorough research and a long-term investment perspective in navigating market cycles [1]

Investors interested in Large Cap Pharmaceuticals stocks are likely familiar with Pfizer (PFE) and Eli Lilly (LLY) . But which of these two stocks is more attractive to value investors? We'll need to take a closer look to find out.Everyone has their own methods for finding great value opportunities, but our model includes pairing an impressive grade in the Value category of our Style Scores system with a strong Zacks Rank. The Zacks Rank is a proven strategy that targets companies with positive earnings est ...

Core Viewpoint - Pfizer is expected to report quarterly earnings of $0.64 per share, reflecting a 22% decline year-over-year, with revenues projected at $13.88 billion, a decrease of 6.7% compared to the previous year [1]. Earnings Estimates - Analysts have not revised the consensus EPS estimate for the quarter in the past 30 days, indicating a stable outlook among analysts [1]. - Changes in earnings estimates are crucial for predicting investor reactions to the stock [2]. Revenue Projections - Analysts estimate 'Revenues- Oncology- Ibrance- Worldwide' at $898.97 million, down 14.7% from the prior year [4]. - 'Revenue- Specialty Care- Cibinqo' is projected to reach $71.20 million, an increase of 69.5% year-over-year [4]. - 'Revenues- Specialty Care- Xeljanz- Worldwide' is expected to be $141.92 million, down 26.9% from the previous year [5]. - 'Revenues- Oncology- Inlyta- Worldwide' is estimated at $207.30 million, indicating a 12.5% decline year-over-year [5]. Regional Revenue Insights - 'Revenues- Oncology- Ibrance- United States' is projected at $565.50 million, down 16.7% from the year-ago quarter [6]. - 'Revenues- Specialty Care- Xeljanz- Total International' is expected to be $101.82 million, reflecting a 15.2% decrease [6]. - 'Revenues- Oncology- Ibrance- Total International' is estimated at $333.47 million, down 11.1% year-over-year [7]. - 'Revenues- Specialty Care- Xeljanz- United States' is projected to be $40.10 million, indicating a significant decline of 45.8% [7]. Additional Revenue Metrics - 'Revenues- Oncology- Inlyta- Total International' is expected to reach $91.42 million, down 4.8% year-over-year [8]. - 'Revenues- Oncology- Inlyta- United States' is projected at $115.88 million, reflecting a 17.8% decline [8]. - 'Revenue- Primary Care- Prevnar family- United States' is estimated at $1.14 billion, a slight decrease of 0.4% from the prior year [9]. - 'Revenue- Primary Care- Prevnar family- Total International' is projected to be $550.39 million, indicating a year-over-year increase of 1.6% [9]. Stock Performance - Over the past month, Pfizer shares have returned -11.2%, compared to the Zacks S&P 500 composite's -5.1% [9]. - Pfizer currently holds a Zacks Rank 2 (Buy), suggesting potential outperformance in the near future [10].

Core Viewpoint - Investing in stocks priced under $30 can yield significant returns, with Pfizer and Adyen identified as two promising options for investors [2]. Group 1: Pfizer - Pfizer's stock has declined from approximately $60 per share in late 2021 to just under $22, primarily due to reduced sales from its COVID-19 portfolio and upcoming patent cliffs, including Eliquis [3][4]. - Despite recent challenges, Pfizer has developed a robust pipeline, particularly in oncology, which is expected to yield significant clinical and regulatory successes in the near future [4]. - The company has shown resilience in its financial performance, with ongoing contributions from its coronavirus products and a strong dividend yield of 7.8%, appealing to income-focused investors [7][8]. Group 2: Adyen - Adyen, a Netherlands-based fintech, offers integrated payment solutions that are essential for multinational companies, boasting clients like Microsoft, Uber, and Spotify [9]. - The company's stock has experienced volatility due to economic challenges affecting transaction volumes and its decision to maintain spending, which impacted margins [10]. - Adyen's strong customer retention due to switching costs and the ongoing shift to e-commerce present significant growth opportunities, making its shares, priced under $16, an attractive investment [11].