Investment Rating - The report maintains a "Recommendation" rating for Kexing Pharmaceutical (688136.SH) [3][10] Core Viewpoints - Kexing Pharmaceutical achieved a revenue of 1.407 billion yuan in 2024, representing an increase of 11.75%, and turned a profit with a net profit of 31 million yuan [4][7] - The company plans to distribute a cash dividend of 0.8 yuan per 10 shares to all shareholders [4] - The overseas sales revenue is expected to grow significantly, with a projected increase of 62% in 2024 [7] - The company is focusing on new emerging markets and has submitted over 120 registration applications for its products in more than 60 countries [7] - Kexing's innovative drug pipeline is progressing, with multiple projects in clinical trials, including two in Phase III [8] Summary by Sections Financial Performance - In 2024, Kexing Pharmaceutical reported a revenue of 1.407 billion yuan, up 11.75% from the previous year, and a net profit of 31 million yuan [4][7] - The company’s operating expenses showed a decrease in sales expense ratio by 12.33 percentage points to 42.42% [7] - The R&D expense ratio decreased by 15.45 percentage points to 11.94% due to reduced clinical and trial costs [7] Market Expansion - The company’s flagship product, albumin paclitaxel, received EU approval in July 2024, with increasing sales orders [7] - Kexing is targeting emerging markets, achieving over 15% sales growth in these regions during the reporting period [7] Innovation Pipeline - Kexing is advancing several projects in clinical trials, including GDF15 monoclonal antibody and dual-specific antibodies targeting VEGF/ANG-2 and IL-4R/IL-31 [8] - The GDF15 project is aimed at treating cancer cachexia and has received IND application acceptance from the Chinese regulatory authority [8] Future Projections - Revenue forecasts for 2025-2027 have been adjusted to 1.935 billion, 2.288 billion, and 2.807 billion yuan respectively [8] - Net profit projections for the same period are revised to 123 million, 243 million, and 357 million yuan respectively [8]

Key Points Summary of the Conference Call for Kexing Pharmaceutical Company Overview - Kexing Pharmaceutical reported a robust performance in 2024, achieving total revenue of 1.85 billion yuan, a year-on-year increase of 60% [4][3] - The company turned a profit with a net profit of 35 million yuan, and EBITDA of 204 million yuan, reflecting over 200% growth [4][3] Financial Performance - Total revenue for 2024 reached 1.4 billion yuan, with a 12% year-on-year growth [3] - Q4 revenue was 317 million yuan, up 27% year-on-year [3] - Overseas sales revenue was 220 million yuan, marking a 60% increase [3][4] - Operating cash flow turned positive, reaching 100 million yuan [4][3] Domestic Market Performance - Domestic sales revenue was 1.18 billion yuan, showing stable growth despite the impact of centralized procurement [5][4] - The company maintained a solid domestic market presence, indicating a stable foundation [5][4] Overseas Market Performance - Kexing's overseas sales grew by 60% in 2024, primarily driven by the sales of interleukin in the EU [6][4] - The company has introduced 16 new products and established branches in multiple regions to enhance marketing capabilities [6][4] Research and Development - R&D expenses remained high at approximately 1 billion yuan, with significant investment in Phase III clinical trials [7][4] - The company is focusing on innovative products based on antibody and protein technology platforms, including the GB05 project for RSV treatment, which has entered Phase III trials [7][4] Future Development Strategy - Kexing aims to focus on protein antibodies and delivery technology innovations over the next five years, planning to establish subsidiaries for collagen, trillion replacements, and anti-tumor products [10][4] - The company targets achieving 6 NDAs and 15 INDs within five years, aspiring to become a high-quality drug export platform covering over 70 countries [10][4] Equity Incentive Plan - Kexing launched a second equity incentive plan in 2024, targeting a sales growth of 200%-400% for 2025, with a minimum sales goal of 60 million USD [9][4] Commercialization and Product Pipeline - The company has formed a trend of "introducing, launching, and scaling" its products, with expectations of reaching a minimum overseas sales peak of 1.5 billion yuan by 2026 or 2027 [12][4] - Kexing is focusing on antibody and protein drug development in oncology and autoimmune fields, emphasizing the Kexing body platform [17][4] Regulatory and Market Expansion - Kexing has established a German subsidiary to enhance its presence in the EU market, with plans to introduce 10 to 20 products focusing on oncology, autoimmune, and metabolic diseases [31][4] - The company is actively researching market demands and competition in Europe to quickly collaborate with domestic partners for product launches [31][4] Conclusion - Kexing Pharmaceutical is committed to innovation and internationalization, with clear strategic goals for the coming years, aiming to enhance its quality and market position [33][4]

医药 2025 年 04 月 14 日 科兴制药(688136.SH) 24年利润端实现扭亏，关注新品海外放量节奏 推荐（维持） 股价：30.00 元 主要数据 | 行业 | 医药 | | --- | --- | | 公司网址 | www.kexing.com | | 大股东/持股 | 深圳科益医药控股有限公司/66.01% | | 实际控制人 | 邓学勤 | | 总股本(百万股) | 200 | | 流通 A 股(百万股) | 200 | | 流通 B/H 股(百万股) | | | 总市值（亿元） | 60 | | 流通 A 股市值(亿元) | 60 | | 每股净资产(元) | 8.19 | | 资产负债率(%) | 48.2 | | 行情走势图 | | 相关研究报告 【平安证券】科兴制药（688136.SH ）*公司动态跟踪 报告*出海业务有望保持高增长，创新药平台价值静待 重估*推荐20250402 证券分析师 | 叶寅 | 投资咨询资格编号 | | --- | --- | | | S1060514100001 | | | BOT335 | | | YEYIN757@pingan.com.cn | | ...

Investment Rating - The industry investment rating is "Outperform the Market" [52] Core Viewpoints - The ongoing US-China tariff policies are causing disruptions, suggesting a focus on non-US market expansion and import substitution opportunities in the biopharmaceutical sector [4][9] - The report highlights that the adjustment of tariffs is expected to impact the trade of pharmaceutical products between China and the US, with companies primarily exporting to markets outside the US being less affected [4][9] - The report emphasizes the potential for domestic products to gain market share in the biopharmaceutical sector due to increased tariffs on US imports [9][10] Summary by Sections Tariff Policy Overview - As of April 11, 2025, the tariff rates for bilateral trade between China and the US have been adjusted to 125%, with China indicating it will not respond to further tariff increases from the US [4][5] Biopharmaceutical Sector Insights - The blood products sector is expected to stabilize prices and increase the market share of domestic products due to tariff impacts on imports, particularly for albumin [9] - The medical device sector is anticipated to accelerate domestic substitution due to reliance on North American production, with specific focus on electrophysiology and imaging products [10] - The report suggests monitoring companies such as Palin Bio, Tian Tan Bio, and Huashan Bio for potential growth opportunities in the blood products market [9][10] Investment Strategies - The report recommends focusing on "innovation," "overseas expansion," "equipment upgrades," and "consumer recovery" as key investment themes [12] - Specific companies highlighted for innovation include BeiGene, Dongcheng Pharmaceutical, and others with strong global competitiveness [12] - Companies like Mindray Medical and United Imaging are noted for their potential in overseas markets [12] Key Companies to Watch - Notable companies include: - **Nocera Biopharma**: Expected to achieve significant revenue growth with its core product, showing a 49% year-on-year increase in sales [13] - **Sino Biopharmaceutical**: Rapid revenue growth with a focus on innovative products [18] - **Kexing Biopharma**: Stable domestic business with promising overseas expansion [18] - The report also highlights the potential of companies like East China Pharmaceutical and others in the nuclear medicine sector [17] Market Performance - The biopharmaceutical sector has seen a decline of 5.61% recently, with specific sub-sectors experiencing varying levels of impact [31][44]

证券研究报告 | 医药生物 | 2025年4月12日 www.hczq.com 华创医药投资观点&研究专题周周谈·第121期 海外CXO 2024财报总结 本周周专题联系人：万梦蝶 | 华创医药团队： | | | --- | --- | | 首席分析师 郑辰 | 执业编号：S0360520110002 邮箱：zhengchen@hcyjs.com | | 联席首席分析师 刘浩 | 执业编号: S0360520120002 邮箱: liuhao@hcyjs.com | | 医疗器械组组长 李婵娟 | 执业编号：S0360520110004 邮箱：lichanjuan@hcyjs.com | | 中药和流通组组长 高初蕾 | 执业编号：S0360524070002 邮箱：gaochulei@hcyjs.com | | 分析师 万梦蝶 | 执业编号: S0360523080008 邮箱: wanmengdie@hcyjs.com | | 分析师 王宏雨 | 执业编号：S0360523080006 邮箱：wanghongyu@hcyjs.com | | 分析师 朱珂琛 | 执业编号：S0360524070007 邮箱 ...

Core Viewpoint - The report highlights the significant growth and strategic advancements of Sinovac Biotech in 2024, emphasizing its dual strategy of "innovation + internationalization" amidst increasing competition in the global pharmaceutical industry [1][5]. Financial Performance - In 2024, Sinovac Biotech achieved a revenue of 1.407 billion yuan, representing a year-on-year growth of 11.75% [1]. - The net profit attributable to shareholders was 31.48 million yuan, with a net profit of 35.25 million yuan after excluding non-recurring gains and losses [1]. R&D Innovation - Sinovac Biotech has transitioned to innovative drug development, with 14 projects in the pipeline, including 4 in clinical stages, focusing on antiviral, oncology, and autoimmune diseases [2]. - The GB18 project, targeting GDF-15 for cancer cachexia treatment, has completed international patent registration and shows promising preclinical data [2]. - The company is leveraging AI and computer-aided drug design (CADD) to enhance antibody molecule design and optimize drug efficacy [2][3]. International Expansion - Overseas revenue surpassed 200 million yuan in 2024, increasing its share of total revenue from 11% in 2023 to 16% [5]. - Sinovac Biotech has shifted from simple product exports to platform-based international collaborations, achieving over 15% sales growth in emerging markets [5]. - The approval of albumin-bound paclitaxel in the EU marks a significant milestone for the company, being the first domestic product to gain such approval [5]. Strategic Advantages - The company emphasizes speed in its international collaboration process, with the ability to submit product registration documents within a month of signing agreements [6]. - Sinovac Biotech provides comprehensive services in market insights, marketing, and risk management to empower its partners [6][7].

Core Viewpoint - The company has shown significant improvement in overall operational quality and steady growth in its main business, with a reported revenue of 1.4 billion yuan, representing a year-on-year increase of 11.75% [1] Group 1: Financial Performance - The net profit attributable to shareholders, excluding non-recurring gains and losses, was 35.25 million yuan [1] - The overseas business revenue reached 224 million yuan, marking a year-on-year growth of approximately 61.96% [1][2] - The proportion of overseas business revenue in total revenue increased from 11% in 2023 to 16% in 2024 [2] Group 2: Research and Development - The company has transformed its R&D focus towards innovative drug development, particularly in the fields of antiviral, oncology, and autoimmune diseases, with 14 projects under research, 4 of which are in clinical stages [1] - The innovative drug GB18, targeting GDF-15 for treating cancer cachexia, has completed international patent layout and shows promising preclinical results [1] - The company is leveraging AI and computer-aided drug design (CADD) for antibody molecule design, achieving breakthroughs such as the GB12 bispecific antibody [2] Group 3: Market Expansion - The company has strategically targeted emerging markets with a population exceeding one billion and rapid economic growth, establishing subsidiaries in countries like Brazil, Mexico, Singapore, Vietnam, and Egypt [3] - Sales in emerging markets grew by over 15% year-on-year during the reporting period [3] - The company's product, EPO injection, has become a leading brand in countries such as Brazil, the Philippines, Egypt, and Peru [3]

创新药概念震荡拉升 海思科涨停创历史新高 智通财经4月11日电，午后海思科封涨停，创出历史新高，一品红涨超10%，科兴制药、阳光诺和、百 奥泰、百济神州、翰宇药业等多股涨超5%。消息面上，兴业证券认为，近期，创新药领域催化剂不 断，包括海外授权、国内政策和临床数据进展等。预计和去年相比今年国产创新药重要数据将较多，有 望为创新药板块带来正面催化。 ...

创新药概念震荡拉升，海南海药（000566）涨停，一品红（300723）、泓博医药（301230）、科兴制 药、海正药业（600267）、中源协和（600645）等跟涨。 暗盘资金正涌入这些股票，点击速看>>> ...

一、主要会计数据和财务指标 | 报告期指标 | 2024年年报 | 2023年年报 | 本年比上年增减(%) | 2022年年报 | | --- | --- | --- | --- | --- | | 基本每股收益（元） | 0.1600 | -0.9600 | 116.67 | -0.4500 | | 每股净资产（元） | 8.19 | 8.16 | 0.37 | 9.1 | | 每股公积金(元) | 6.45 | 6.43 | 0.31 | 6.41 | | 每股未分配利润(元) | 0.76 | 0.63 | 20.63 | 1.59 | | 每股经营现金流(元) | - | - | - | - | | 营业收入(亿元) | 14.07 | 12.59 | 11.76 | 13.16 | | 净利润(亿元) | 0.31 | -1.9 | 116.32 | -0.9 | | 净资产收益率(%) | 1.94 | -11.11 | 117.46 | -4.87 | 数据四舍五入，查看更多财务数据>> 前十大流通股东累计持有： 14480.63万股，累计占流通股比： 72.54%，较上期变化： -170.6 ...