文｜周涛 科兴制药的创新药研发近期取得重要进展。9月24日，科兴制药披露公司管线人干扰素α1b吸入溶液被 国家药品监督管理局药品审评中心纳入突破性治疗品种名单。 作为儿童呼吸道合胞病毒（RSV）专用药，该药有望成为全球首款干扰素吸入制剂，为全球儿童呼吸道 感染提供新的解决方案。呼吸道合胞病毒（RSV）是引起婴幼儿急性呼吸道感染最常见的病毒病原， WHO关于儿童急性呼吸道感染的病因学研究表明，RSV感染占儿童呼吸道疾病的60%以上。 科兴制药（688136.SH）在9月底宣布筹划发行H股赴港上市，成为当月25家公告拟赴港上市的A股公司 之一。在这波"A+H"股热潮中，截至10月2日，还有76家A股公司已向港交所递表排队等待聆讯。 纵观此次赴港上市潮，不仅包括立讯精密、牧原股份等知名企业，医药企业更是表现突出。科兴制药在 公告中表示，赴港上市目的是为了深化公司"创新+国际化"的战略布局，加快海外业务发展，拓宽多元 融资渠道。 今年以来，资本市场上的"A+H"模式愈发受到国内上市公司的青睐。仅9月份就有25家A股上市公司先 后公告筹划赴港上市，其中包括领益智造、博瑞医药、海澜之家、科大智能等各行业龙头企业。 从行业 ...

科兴制药（688136.SH）在9月底宣布筹划发行H股赴港上市，成为当月25家公告拟赴港上市的A股公司之一。在这波"A+H"股热潮中，截至10月2日，还有76家A股公司已向港交所递表排队等待 纵观此次赴港上市潮，不仅包括立讯精密、牧原股份等知名企业，医药企业更是表现突出。科兴制药在公告中表示，赴港上市目的是为了深化公司"创新+国际化"的战略布局，加快海外业务发展 今年以来，资本市场上的"A+H"模式愈发受到国内上市公司的青睐。仅9月份就有25家A股上市公司先后公告筹划赴港上市，其中包括领益智造、博瑞医药、海澜之家、科大智能等各行业龙头企 从行业分布来看，覆盖了医药生物、通信、食品饮料、汽车、机械设备等多个行业。其中，"A+H"上市模式表现尤为突出，上半年相关企业集资额占同期总融资额的七成。 根据科兴制药2025年半年度报告，公司上半年实现营业收入7.0亿元，同比下降7.82%；但归母净利润达到8034.45万元，同比大幅上升576.45%。 公司表示，受集采等因素影响，国内销售收入有所下降，但随着白蛋白紫杉醇在欧洲市场放量增长，海外收入同比大幅增长，公司上半年总体收入同比仅小幅下降。 值得注意的是，科兴制药经 ...

Group 1 - The forum "Emerging Market Development Forum for China's Pharmaceutical Industry" was successfully held during the 2025 CPHI & PMEC Pharmaceutical Industry Exhibition in Shenzhen, focusing on opportunities and challenges in emerging markets [1] - The Shenzhen Pharmaceutical and Medical Device Industry Outbound Union aims to create a collaborative ecosystem for companies to expand internationally, involving major enterprises and professional service institutions [1] - The forum featured industry leaders discussing the evolution of the global pharmaceutical landscape and innovative practices for internationalization, highlighting the growing interest in emerging markets [1] Group 2 - IQVIA's analysis indicates that the global biopharmaceutical market is undergoing significant restructuring, with China accounting for one-third of global innovation in drug development [2] - The report emphasizes that Chinese pharmaceutical companies are entering a new era of internationalization, with opportunities arising from technological advancements and innovative business models [2] - The "API+ANDA," "NewCo," and "JV" outbound models were discussed, outlining their characteristics and advantages [2] Group 3 - The MENA and South Asia regions are identified as key markets, with a pharmaceutical market size of approximately $35 billion and an annual growth rate of 6.3%, projected to increase by 35% to 55% over the next five years [3] - Kexing Pharmaceutical's localized marketing strategies in Algeria, Egypt, and Saudi Arabia demonstrate the potential for Chinese pharmaceutical companies in the MENA region [3] - In South America, regulatory compliance and local partnerships are crucial for market entry, with Brazil being the largest contributor to growth in the region [3] Group 4 - The roundtable discussion highlighted the role of new productive forces in the pharmaceutical sector, focusing on biotechnological innovation, digital R&D, and intelligent management [4] - Chinese pharmaceutical companies are encouraged to collaborate with trustworthy partners to enhance their international competitiveness through innovation and ecological synergy [4] - The successful forum aims to provide strategic guidance for Chinese pharmaceutical companies looking to enter emerging markets, with Kexing Pharmaceutical committed to building high-level international exchange platforms [4]

Investment Rating - The report maintains a "Buy" rating for the company [10] Core Views - The company reported a revenue of 700 million yuan in the first half of 2025, reflecting a year-on-year decrease of 7.82%, while the net profit attributable to the parent company was 80 million yuan, showing a significant increase of 576.45% [6][10] - The growth in net profit outpaced revenue growth, attributed to improved operational quality and rapid growth in overseas sales, with export revenue reaching 188 million yuan, doubling year-on-year [7][10] - The company is advancing its "global selection and coverage" strategy, with 19 products having obtained overseas commercialization rights and approximately 150 registration applications submitted in over 70 countries/regions [8] - The company has laid out multiple innovative drug pipelines, with 10 innovative drugs disclosed, most of which are global firsts, potentially providing a second growth engine [8] Financial Summary - Total revenue for 2025 is projected at 1.615 billion yuan, with a year-on-year growth rate of 14.8% [5] - The net profit attributable to the parent company is expected to be 108 million yuan in 2025, with a significant year-on-year growth of 244.2% [5] - The company’s gross margin is projected to be 65.3% in 2025, with a return on equity (ROE) of 6.1% [5]

Group 1 - Since August, nearly 20 A-share listed companies have announced plans to list in Hong Kong, with companies like Luxshare Precision and Victory Technology formally submitting H-share listing applications [1][6] - The main motivations for these companies to pursue a Hong Kong listing include expanding international strategies, optimizing overseas business layouts, enhancing brand recognition, and improving overseas financing capabilities [1][5] Group 2 - The recent A-share companies planning to list in Hong Kong span various industries, including electronics, machinery, pharmaceuticals, food and beverage, chemicals, and media, with the electronics sector being the most concentrated [5][6] - Notable companies in the electronics sector include Huajin Technology, Chipsea Technologies, and Luxshare Precision, while the pharmaceutical sector features companies like Sinovac Biotech and Kefu Medical [5][6] Group 3 - Industry analysts suggest that sectors with strong global attributes, such as resource energy, equipment manufacturing, and pharmaceutical innovation, are more likely to benefit from the "A+H" listing strategy [5][7] - For instance, Sinovac Biotech aims to deepen its "innovation + internationalization" strategy through its Hong Kong listing, which will accelerate overseas business development and enhance its international brand image [5][6] Group 4 - Companies in the electronics industry, such as Jinghe Integration and Huajin Technology, believe that listing in Hong Kong will help them expand overseas customer bases and optimize investment layouts [6][7] - Leading companies like Luxshare Precision, with a market value exceeding 300 billion, plan to use the funds raised from their IPO for capacity expansion and technological research [6][7] Group 5 - Market analysts indicate that large state-owned enterprises and industry leaders prefer the "A+H" model to support long-term international financing needs, while mid-sized growth companies can enhance international investor recognition through this model [7] - The new regulations effective from August 4 at the Hong Kong Stock Exchange have improved the pricing and public market rules for initial public offerings, which is expected to further encourage A-share companies to list in Hong Kong [7]

Core Insights - The company reported a significant increase in revenue and net profit for the first half of the year, with revenue reaching 700.46 million yuan and net profit at 80.34 million yuan, marking a year-on-year growth of 576.45% [1] - The company is positioning itself as an innovative multinational pharmaceutical enterprise through its focus on research and development and international expansion [1] Innovation and R&D - The company has established a robust innovation pipeline based on its recombinant protein drug technology platform, focusing on high-value clinical pipelines and antibody drug development technology [2] - The company is developing several new drugs, including GB05 for respiratory syncytial virus (RSV) and GB18 for cancer cachexia, with promising clinical trial results [2][3] - The GB12 project targets specific dermatitis with a dual-blocking mechanism, showing significant advantages over existing treatments, indicating a favorable competitive landscape [3] - The company is also advancing the GB24 project, which addresses intestinal fibrosis in inflammatory bowel disease (IBD) patients, enhancing its competitive edge in gastrointestinal diseases [4] International Expansion - The company has made significant strides in its international commercialization strategy, establishing a marketing network covering over 70 countries and regions [5][6] - The company has successfully registered 18 products for overseas commercialization and received approvals in multiple countries, including the EU [6] - The introduction of high-end complex formulations, such as albumin paclitaxel, marks a transition to a new phase of international expansion, broadening the product portfolio [6] Strategic Positioning - The company is recognized for its innovative capabilities and has been actively participating in international academic events, enhancing its image as an innovative multinational biopharmaceutical enterprise [4][7] - The strategic focus on both innovation and internationalization is expected to drive sustainable growth and establish a positive image for Chinese enterprises in the global market [5][7]

Core Viewpoint - The company reported significant growth in revenue and net profit for the first half of 2025, indicating strong performance and successful market expansion efforts [1][2]. Financial Performance - The company achieved a revenue of 700 million yuan and a net profit of 80.34 million yuan, representing a year-on-year increase of 576.45% [1]. Research and Development - The company has made notable advancements in R&D, receiving clinical trial approvals for multiple products, including GB18 injection and interferon α1b inhalation solution [1]. - Ongoing clinical trials include Phase I for long-acting growth hormone and Phase III for polyethylene glycol-conjugated granulocyte colony-stimulating factor injection and interferon α1b inhalation solution [1]. Market Expansion - The company is accelerating its overseas market expansion, with its albumin-bound paclitaxel showing a 35.84% quarter-on-quarter revenue increase in the EU market [1]. - Approximately 60 registration applications have been accepted in about 40 countries, with approvals in emerging markets like Indonesia and Peru [1]. Product Portfolio - The company has introduced significant products such as trastuzumab and abicipar injection solution, totaling 19 products with overseas commercialization rights [2]. - The strategy includes extending from emerging markets to regulated markets and upgrading from biosimilars to innovative drugs [2]. Domestic Market Strategy - The company is enhancing regional management and expanding e-commerce channels, with a 90% year-on-year increase in e-commerce revenue [2]. - The production capacity is also ramping up with the launch of the pre-filled production line [2]. Industry Outlook - The pharmaceutical industry is transitioning towards innovation-driven growth, supported by policy and technological advancements [2]. - The company aims to strengthen its core business while focusing on market expansion and management improvement to enhance profitability [2].

Core Viewpoint - Kexing Pharmaceutical (688136.SH) plans to sell its wholly-owned subsidiary, Shenzhen Tong'an Pharmaceutical Co., Ltd., for 15 million yuan to reduce management costs and improve asset operation efficiency [1][13]. Group 1: Company Performance - Kexing Pharmaceutical's stock price has doubled since the beginning of the year, with a significant increase of 156.50% from 21.86 yuan per share at the end of 2024 to 56.07 yuan on June 4 [6][10]. - The company reported a revenue of 14.07 billion yuan in 2024, an increase of 11.75% year-on-year, and achieved a net profit of 31 million yuan, marking a turnaround from previous losses [10][11]. - Despite the revenue growth, the company's R&D expenses significantly decreased to 168 million yuan in 2024, down 51.30% from the previous year [11][13]. Group 2: Shareholder Actions - The controlling shareholder, Shenzhen Keyi Pharmaceutical Holdings Co., Ltd., plans to reduce its stake by up to 3%, potentially cashing out over 336 million yuan based on the stock price at the time of the announcement [4][5]. - This is the first time since Kexing Pharmaceutical's IPO that the major shareholder has announced a reduction in holdings, raising market concerns about the intention behind the move [3][5]. Group 3: Market Reactions - Following the announcement of the major shareholder's reduction plan, Kexing Pharmaceutical's stock price fell to 50.95 yuan per share by June 12 [8]. - Market skepticism arose due to the significant stock price increase prior to the reduction announcement, with some investors questioning the motives behind the shareholder's decision [5][6].

Core Viewpoint - The company has established a clear strategy of "innovation + overseas commercialization" and has achieved significant results through five years of careful planning [1] Group 1: Overseas Commercialization Strategy - The company's overseas commercialization strategy focuses on high-quality Chinese pharmaceuticals entering global markets, emphasizing "global selection and global coverage" [2] - The 2.0 strategy includes expanding from emerging markets to the EU, transitioning from biosimilars to high-end complex injectable formulations, and localizing operations [2] - The company aims to enhance its international competitiveness by upgrading product structures and establishing a strong localized operational network in key global markets such as Brazil, Mexico, and Germany [2] Group 2: Innovation and Clinical Development - The company is committed to completing a certain number of innovative drug clinical applications in the US and China each year to accelerate the internationalization of its product pipeline [2] - The company is strengthening its business development capabilities by forming specialized teams in China and Europe and actively seeking deep collaborations with leading global pharmaceutical companies [2] - Several innovative drug projects are currently in the negotiation stage, and the company is increasing its academic exchanges to enhance its international influence in innovative drug research [2] Group 3: Future Growth and Market Expansion - The company has laid a solid foundation for its overseas commercialization strategy since its establishment in 2021, with good sales performance of its albumin paclitaxel product in the EU market [3] - The company plans to introduce new products and drive sales through its established overseas commercialization platform, aiming for long-term business growth [3] - The company targets a 200%-400% increase in export revenue by 2025 compared to 2023, as outlined in its 2024 equity incentive plan [3]

Core Viewpoint - The company is actively adjusting its supply chain in response to the 20% tariff challenge and is focusing on high-barrier, high-margin products to maintain its competitive edge in the pharmaceutical industry [2][4]. Company Overview - The company, Jianyou Co., Ltd., is a pharmaceutical enterprise engaged in drug research, production, and sales, with a diverse product pipeline including cardiovascular, neurological, anesthetics, anti-tumor preparations, and high-value sterile injectables [4]. Financial Performance - In Q1 2025, the company reported a main revenue of 885 million yuan, a year-on-year decrease of 11.85% - The net profit attributable to shareholders was 84.71 million yuan, down 52.19% year-on-year - The net profit after deducting non-recurring gains and losses was 75.32 million yuan, a decline of 56.05% - The debt ratio stood at 26.38%, with investment income of 11.13 million yuan and financial expenses of 21.80 million yuan - The gross profit margin was 34.41% [4]. Product Development - The company’s biosimilar drugs are entering a harvest period, with liraglutide expected to receive FDA approval in April 2024, making the company the third globally to enter the market - Sales of adalimumab (Yusimry) have already surpassed 70 million yuan - Collaborations with Tonghua Dongbao and Double Star Pharmaceutical are progressing well, with a focus on insulin and paclitaxel products [4]. Market Strategy - The company views the U.S. market as a significant revenue source and plans to expand into Europe, the Middle East, and Central and South America by 2030, aiming to become a global enterprise [2][4]. Analyst Ratings - In the last 90 days, 9 institutions have given buy ratings for the stock, with an average target price of 19.21 yuan [5]. Profit Forecast - Detailed profit forecasts indicate expected net profits for 2025 ranging from 10.25 billion yuan to 12.18 billion yuan, with projections for 2026 and 2027 also showing growth [7]. Financing Activity - In the past three months, the stock has seen a net inflow of 52.81 million yuan in financing, with an increase in financing balance, while the net inflow of short selling was 953,600 yuan [7].