中国的发酵产能占全世界70%以上。 2025年政府工作报告明确提出，建立未来产业投入增长机制，培育生物制造等未来产业。 聚焦生物制造热点领域和重要课题，工业和信息化部近日遴选发布了16项人工智能在生物制造领域应用典型案例，组织开展了生物制造标志性产品、生物制 造中试平台遴选发布，生物反应器揭榜挂帅等工作。 清华大学副校长王宏伟在论坛上表示，生物制造是科技创新和产业创新融合发展的重要领域，具备引领第四次工业革命的潜力，将会带来重构传统制造业的 生产模式，替代传统天然产物的获取方式，颠覆传统农业的种养殖模式等一系列重大变革。 王宏伟谈到，据预测，2050年生物制造有望创造30万亿美元的经济价值，占全球制造业的1/3。当前，我国生物制造领域已经进入技术突破和产业化加速的 关键阶段，还需要各方共同努力，加强核心技术攻关，提升要素配置水平，构建友好应用环境。 常德作为湖南生物制造产业的重要基地，发展势头强劲。2024年，常德市合成生物制造企业35家实现产值125亿元，今年1-8月产值增长24.01%，利尔生物、 鸿健生物、引航生物等重点企业产值分别增长103.9%、101.1%、48.3%，跑出了产业发展"加速度"。 ...

Core Viewpoint - The launch of D-allulose by COFCO Group marks a significant advancement in China's high-end functional sugar market and breaks international technological monopolies in the field of biological manufacturing [1][2]. Group 1: Product Launch and Market Impact - COFCO Group, through its subsidiaries, has introduced the first domestically produced D-allulose product, filling a gap in the high-end functional sugar market in China [1]. - D-allulose is recognized as a promising sugar substitute, with a sweetness level approximately 70% that of sucrose but only 10% of its calories, making it suitable for various food applications [1]. - The global D-allulose market is projected to reach $14.77 million in 2024, with a compound annual growth rate (CAGR) exceeding 14% from 2025 to 2034 [1]. Group 2: Industry and Health Implications - The introduction of D-allulose aligns with national public health initiatives, such as the "Weight Management Year," providing essential support for the Healthy China strategy [2]. - The product opens new innovation opportunities in low-sugar tea and baking industries, allowing consumers to enjoy healthier sweetness without compromising taste [2]. Group 3: Technological Advancements and Research - COFCO Group has invested significantly in research and development, successfully developing high-performance D-allulose-3-epimerase after extensive trials and genetic modifications [2]. - The company has established a comprehensive patent portfolio related to the biological synthesis of D-allulose, covering production strains, enzyme preparations, and separation processes, with 10 core patents already authorized [2][3]. - COFCO Group's commitment to technological innovation is reflected in its strategic initiatives, including policies that incentivize research and development as a core part of its business strategy [3].

Group 1 - Henan has established itself as a crucial grain production area, focusing on food security and enhancing crop yields through technology and management [1][3] - The province has developed a diversified food supply system, with significant production in oilseeds, edible fungi, and livestock, leading to the establishment of 18 industrial chains [3][25] - Henan's food industry has evolved from being a grain storage hub to a significant player in the global food market, producing a variety of products including traditional and emerging snacks [5][10] Group 2 - The production of spicy strips in Henan has reached over 10 billion packages annually, supported by 75,000 tons of high-quality wheat flour [10][12] - The establishment of wheat industrial alliances has ensured stable raw material supply for food companies, enhancing their market confidence [12][14] - The province is transitioning from primary processing to deep processing in the food industry, with government support for technological advancements [16][19] Group 3 - The Central Plains Food Laboratory has become a key driver of innovation, collaborating with enterprises to develop healthier food processing techniques [19][22] - Henan produces a significant portion of various food products in China, including half of the country's ham sausages and three-fifths of dumplings [25] - The province is enhancing its meat processing capabilities and implementing modern cold chain logistics for meat products [29][31] Group 4 - New food products like spicy strips and tea beverages are gaining popularity, with some brands expanding internationally [33][35] - The government is facilitating brand promotion and consumer engagement through various activities and logistics improvements [35][38] - The number of large-scale agricultural processing enterprises in Henan has reached 6,103, with plans for further technological integration in the food sector [38]

Industry Insights - The launch of D-alloheptulose, the first domestic product of its kind, fills a gap in the high-end functional sugar market in China and signifies a breakthrough in biomanufacturing technology [1] - D-alloheptulose is recognized for its low energy content and non-glycemic properties, making it a potential substitute for traditional food sweeteners, with safety approvals from multiple countries [1] - The global market for D-alloheptulose is projected to reach $147 million by 2024, with an expected compound annual growth rate (CAGR) of 14% from 2025 to 2034 [1] Company Developments - Bailong Chuangyuan is noted as the first company in China to achieve industrial-scale production of D-alloheptulose [3] - Baolingbao is one of the earliest companies to invest in D-alloheptulose projects, currently operating over 5,000 tons of production capacity, with plans to expand to 30,000 tons by 2026 [3] Market Dynamics - Currently, all D-alloheptulose products from China are exported, but domestic applications are expected to accelerate following its official approval [2]

Core Insights - The launch of D-allulose by COFCO Group marks a significant breakthrough in China's high-end functional sugar sector, filling a gap in the domestic market and supporting the health transformation of the food industry [1][2] - D-allulose, a low-calorie sugar alternative, is expected to see substantial market growth, with a projected global market size of $14.77 million in 2024 and a compound annual growth rate exceeding 14% from 2025 to 2034 [1][2] Company Developments - COFCO Group has established a comprehensive patent portfolio in the biosynthesis of D-allulose, with 17 patents covering production strains, enzyme preparations, separation processes, and overall production technology, of which 10 core patents have been authorized [2] - The company has developed a one-stop application solution and differentiated supply capabilities across various sectors, including beverages, baking, dairy, and confectionery, to accelerate the domestic application of D-allulose [2] Industry Impact - The introduction of D-allulose aligns with national public health initiatives, such as the "Weight Management Year," providing significant industrial support for the Healthy China strategy [2] - COFCO Group's commitment to innovation is reflected in its establishment of a dedicated technology innovation department and policies aimed at enhancing R&D investment and sharing benefits with researchers, fostering a collaborative ecosystem for the health food industry [3]

9月23日，由中粮集团旗下中粮生物科技、中粮营养健康研究院联合研发生产的国内首个D-阿洛酮糖产 品在北京正式发布。 作为中国最大的农粮食品企业，中粮集团敏锐洞察消费者趋势，开展战新产业（300832）布局。2017年 起，中粮集团旗下中粮生物科技、中粮营养健康研究院启动专项攻关，从498个基因库中筛选改造，历 经上千次突变体试验，最终突破性开发出高性能D-阿洛酮糖-3-差向异构酶，并于2023年获批国内首款 该酶类食品加工用酶制剂，打破了技术壁垒对D-阿洛酮糖产能的制约。 "经过8年科研攻关与系统性布局，这款健康代糖的甜蜜滋味终于可以抵达国人的舌尖。"中粮营养健康 研究院生物技术中心主任王小艳表示，"我们将加速推进生物制造技术在食品领域的深度开发，让国民 健康红利持续释放。" 截至目前，中粮集团已在生物法合成阿洛酮糖方面完成系统的专利布局，涵盖生产菌种、酶制剂、分离 工艺及整体生产工艺等17项专利，其中10项核心专利已获授权，并形成了产业化的成套技术与装备体 系，构建起覆盖饮料、烘焙、乳品、糖果等多元场景的"一站式应用解决方案"与"差异化供应能力"，为 D-阿洛酮糖在国内的加速应用提供了有力支撑。 这颗小小的 ...

Core Viewpoint - The bio-manufacturing industry is entering a new phase of accelerated development characterized by clear policies, specific support, and close integration with the real economy [7]. Policy Developments - The National Development and Reform Commission (NDRC) has emphasized the importance of bio-manufacturing as a key part of light industry upgrades, particularly in sectors such as plastic products, textiles, food and beverages, household chemicals, cosmetics, leather, and paper industries [6]. - The recent announcement from the Ministry of Industry and Information Technology highlights support for bio-based, biodegradable materials, and bio-manufacturing industries as part of the "Light Industry Growth Stabilization Work Plan (2025-2026)" [6]. Industry Transformation - Bio-technology is driving a systematic transformation of the light industry from a "resource-consuming" and "cost-competitive" model to a new paradigm focused on green, intelligent, and high-end development through raw material revolution, process innovation, functional upgrades, and supply chain security [6]. Economic Integration - The government is guiding localities to develop new growth engines such as artificial intelligence and bio-manufacturing, focusing on the integration of these technologies into traditional industries to enhance productivity and innovation [4].

Core Insights - The event "Biomanufacturing Leading the Future" was successfully held in Hefei as part of the 2025 World Manufacturing Conference, attracting over 230 participants from various sectors [1][3] - The focus was on the biomanufacturing industry, discussing key common links and development hotspots, and aiming to create a comprehensive biomanufacturing ecosystem [3][4] Industry Development - Anhui Province has established a comprehensive biomanufacturing industry system covering six sectors: biopharmaceuticals, bio-food, bio-energy, biomaterials, biochemistry, and enzyme preparations [3] - The province has developed three billion-level industry clusters in biopharmaceuticals, bio-food, and bio-energy, with leading companies like Huaheng Bio and Fengyuan Group [3][4] - A 3 billion yuan biomanufacturing industry fund has been established through cooperation between central and local governments [3] Strategic Initiatives - Hefei is integrating biomanufacturing into its new industrial cluster system, forming a dedicated task force and implementing supportive policies [4] - The establishment of the Synthetic Biology Innovation Research Institute and the Hefei (Changfeng) Synthetic Biomanufacturing Industrial Park aims to create a nationally influential biomanufacturing hub [4] Collaborative Efforts - Key projects and funds were signed during the event, including the Synthetic Biology Multiscale Incubation Center and AI-driven biomanufacturing platforms [4] - The establishment of the Anhui Biomanufacturing Industry Alliance will facilitate the gathering of innovative resources and promote the commercialization of research outcomes [7] Future Outlook - Anhui plans to optimize its industrial layout and enhance collaboration among government, industry, academia, research, finance, and services to foster a "four-chain integration" industrial ecosystem [8]

Core Insights - The event "Biomanufacturing Leading Future Industrial Pattern" held in Changfeng, Hefei, is part of the 2025 World Manufacturing Conference, focusing on biomanufacturing as a key industry [1][3] - The Hefei Biomanufacturing Provincial Future Industry Pilot Zone is the only pilot zone in Anhui Province dedicated to life sciences [1][3] Group 1: Event Overview - The event emphasized the importance of biomanufacturing, discussing key common links and hot subfields, and aimed to promote industrial integration and cluster development [3] - The Hefei Biomanufacturing Provincial Future Industry Pilot Zone was officially approved in October 2024, with plans for the Hefei Synthetic Biomanufacturing Industrial Park [3] Group 2: Industry Development - The pilot zone has made significant progress in its first year, with major projects like the AI-driven biomanufacturing R&D base and microbial agent technology application base set to be completed soon [3] - The pilot zone currently hosts two listed biomanufacturing companies, with one more planning to go public next year, and five key enterprises are expected to achieve a combined output value of 4 billion yuan in 2024 [3][4] Group 3: Regional Focus - Anhui Province has established a comprehensive biomanufacturing industry system covering six sectors, with biopharmaceuticals, bio-foods, and bio-energy clusters each exceeding 10 billion yuan in scale [4] - Changfeng County aims to reach a biomanufacturing output value of 15 billion yuan by 2027 and over 30 billion yuan by 2030, with plans to establish four provincial-level innovation platforms and cultivate ten leading enterprises [5][7]

Core Viewpoint - The article discusses the "Light Industry Stabilization and Growth Work Plan (2025-2026)" issued by the Ministry of Industry and Information Technology, the Ministry of Commerce, and the State Administration for Market Regulation, which aims to enhance the quality and reasonable growth of the light industry, with a focus on supporting emerging fields such as bio-based and biodegradable materials, as well as bio-manufacturing [2][3][5]. Group 1: Policy Support for Bio-based and Biodegradable Materials - The plan explicitly supports technological innovation in bio-based and biodegradable materials, encouraging companies to replace traditional high-pollution materials, particularly in packaging and daily chemical products [5][6]. - The government will promote the development of bio-based and biodegradable materials through funding for green manufacturing and technology transformation projects [5]. - A green standard system will be established to facilitate the certification and international alignment of green products [5]. Group 2: Bio-manufacturing as a Growth Engine - Bio-manufacturing is highlighted as a key growth point, mentioned six times in the plan, alongside sectors like smart home products and the silver economy [6][9]. - The plan includes measures to accelerate product innovation in bio-manufacturing and related fields through initiatives like "chain leader system" and "ranking system" [7]. - The government aims to cultivate over 20 pilot platforms for bio-manufacturing by 2027 to support large-scale industrialization [10][13]. Group 3: Industry Collaboration and Development - The plan emphasizes the importance of industry chain collaboration, encouraging partnerships between bio-based material companies and downstream industries such as home appliances and packaging [5][8]. - It promotes the establishment of cross-industry and cross-disciplinary communication mechanisms to enhance collaborative innovation efficiency [8]. - The government will support the transfer of industries to central and western regions, fostering the growth of bio-manufacturing and related sectors [9].