内容概要：牙探针是在口腔治疗时，对口腔内窝洞的深浅和大小、根管状态及牙龈状态等进行诊查的一 种口腔科医疗器械，根据《医疗器械分类目录》的分类，属于一类医疗器械。在临床上，牙探针可以用 于测定牙周袋的深度，是否探诊出血、角化龈宽度、牙龈厚度、牙间隙宽度、牙齿松动度、病损大小 等。从牙探针产业链来看，上游为制造所需原材料，包括不锈钢、钴基合金、塑料等，中游为牙探针制 造厂商，下游为牙探针应用，应用场景包括口腔医院、口腔诊所、综合性医院等。其中口腔医院在2024 年占市场份额最大，贡献了约45%，其次是口腔诊所，占比为30%。综合性医院占比约15%，其他应用 占10%。在口腔保健意识增强、牙科疾病发病率上升等因素推动下，全球牙科服务需求不断上涨。牙探 针作为检查和诊断牙科疾病的重要工具，也迎来需求增长。数据显示，2024年全球牙探针市场规模约为 12亿美元，预计到2033年市场规模将达21亿美元。从地区分布来看，牙探针市场发展情况与当地经济水 平具有一定的关联性，经济越发达的地区，对牙齿健康的重视程度越高，因此北美、欧洲、亚太为牙科 探主要市场。其中北美占据了牙探针市场的主导地位，2024年占比约40%。欧洲占比3 ...

Core Insights - Approximately 3.5 billion people are affected by oral health issues, which pose a significant public health challenge, particularly in underdeveloped regions [2] - Poor oral health is increasingly linked to a higher risk of esophageal cancer (EC), which includes two main pathological subtypes: esophageal adenocarcinoma (EAC) and esophageal squamous cell carcinoma (ESCC), leading to around 445,000 deaths annually [2] - The oral microbiome plays a crucial role in the pathogenesis of esophageal cancer, yet its exact mechanisms remain to be fully understood [2] Research Findings - A study published in Cell Reports Medicine by researchers from Fudan University mapped the oral microbiome landscape and its interplay with poor oral health in the risk of esophageal squamous cell carcinoma [3][4] - The research analyzed metagenomic sequencing data from 390 pairs of ESCC case-control samples and 206 pairs of newly diagnosed EC case-control samples [6] - The study identified changes in 50 bacterial species in ESCC, such as an increase in Porphyromonas catoniae and a decrease in Campylobacter rectus, along with disruptions in 54 biochemical pathways [6] - The association between poor oral health and ESCC risk was more pronounced in populations with lower levels of Streptococcus mitis, indicating a potential link to thiamine recycling and energy metabolism pathways [6][8] Implications - The findings underscore the potential for targeted interventions on the oral microbiome to improve oral health and prevent or treat esophageal squamous cell carcinoma [10]

Core Points - The article emphasizes the importance of brushing teeth at least twice a day to maintain oral health and prevent dental issues such as cavities and periodontal disease [4][6]. Group 1: Importance of Brushing Twice Daily - Oral health is threatened by two main enemies: cavities and periodontal disease, caused by bacteria that accumulate on teeth [4]. - Bacterial plaque formation occurs in stages, with significant maturation happening within 24 hours, making it crucial to brush at least twice daily to prevent plaque from becoming difficult to remove [5][6]. Group 2: Importance of Nighttime Brushing - Nighttime brushing is particularly important as it helps control the bacterial load on teeth, especially since saliva production decreases during sleep, reducing natural cleaning [9]. - Brushing at night effectively removes food residues accumulated throughout the day, which can feed bacteria and lead to tooth decay [10]. - Nighttime brushing helps eliminate dental plaque, reducing the risk of cavities and periodontal disease [11]. - It also mitigates oral odor caused by bacteria breaking down food residues, which can be more pronounced if brushing is skipped [12].

Core Viewpoint - The article emphasizes the importance of brushing teeth at least twice a day to maintain oral health and prevent dental issues such as cavities and periodontal disease. Summary by Sections Importance of Brushing Twice Daily - Brushing twice a day is essential to combat the two main enemies of oral health: cavities and periodontal disease, which are caused by bacteria accumulating on teeth surfaces over time [1]. Stages of Plaque Formation - **Initial Attachment (0-2 hours)**: After brushing, a small number of loose bacteria begin to attach to the teeth using a saliva film [2]. - **Bacterial Attachment (2-12 hours)**: More bacteria attach to the teeth, becoming more firmly established [3]. - **Mature Plaque (12 hours)**: Attached bacteria start to reproduce and form a complex biofilm structure, making it harder to remove [4]. - **Fully Matured Plaque (24 hours)**: After 24 hours, plaque becomes a complex microbial community that poses a significant threat to oral health, leading to cavities and periodontal diseases [5]. Importance of Nighttime Brushing - Nighttime brushing is crucial as saliva production decreases significantly during sleep, reducing the natural cleaning effect of saliva [8]. - Food residues in the mouth can lead to an acidic environment that erodes tooth enamel, making nighttime brushing vital to remove these residues [9]. - Bacteria proliferate rapidly at night, and brushing before sleep helps to minimize plaque accumulation and reduce the risk of dental issues [10]. - Oral odor is often worse in the morning due to bacterial activity overnight; brushing at night helps to mitigate this issue [11]. - Oral health is linked to overall health, and nighttime brushing can reduce the risk of chronic diseases by lowering bacterial levels in the mouth [11]. Conclusion - Establishing a nighttime brushing routine is essential for both short-term and long-term oral health, and parents should encourage this habit in their children [11].

Core Insights - The article emphasizes the importance of oral health, particularly highlighting periodontal disease as a significant risk factor for various systemic diseases, including cardiovascular diseases, which are often referred to as "silent killers" [1][3]. Group 1: Periodontal Disease and Systemic Health - Periodontal disease can double the incidence of fatal heart disease and increase the risk of myocardial infarction by 30% [1]. - Severe periodontal disease in pregnant women is associated with higher rates of preterm birth and low birth weight [3]. - Diabetic patients with severe periodontal disease have a sixfold higher probability of worsening blood sugar levels compared to those without periodontal issues [3]. Group 2: Prevention and Treatment of Periodontal Disease - Early identification of plaque and tartar accumulation is crucial to prevent the progression of periodontal disease [4]. - Common treatments for periodontal disease include scaling (cleaning), subgingival curettage, periodontal surgery, and tooth extraction, with antibiotics serving only as adjunctive therapy [6]. - Good oral hygiene practices, such as brushing twice daily for at least two minutes and using dental floss, are essential for prevention [7]. Group 3: Oral Cancer Awareness - Oral cancer incidence is rising in China, particularly among middle-aged men aged 40 to 60 [9]. - Common risk factors for oral cancer include smoking, alcohol consumption, and betel nut chewing [10][12]. - Symptoms such as persistent ulcers, bleeding, and unusual growths in the mouth should prompt immediate medical attention [12]. Group 4: Misconceptions in Dental Care - The belief that dental cleaning causes gum recession is incorrect; gum recession is often due to pre-existing inflammation [14][15]. - Not all wisdom teeth need to be extracted; only those that are problematic should be removed [16][18]. - The notion that losing teeth is an inevitable part of aging is misleading; periodontal disease is a primary cause of tooth loss, and maintaining dental health can significantly impact longevity [20].

Core Viewpoint - The event "China Oral New Health Action · 2025 National Love Teeth Day" focuses on building a new protective wall for oral health in China, emphasizing the importance of collaboration among various sectors to enhance oral health awareness and practices [1][7]. Group 1: Event Overview - The event was organized by the China Oral Cleaning and Care Products Industry Association and supported by various organizations, gathering over a hundred representatives from government, industry, academia, and media [1]. - The theme of the event was "Building a New Protective Wall for Oral Health," aiming to discuss innovative development paths for the oral health industry and contribute to the "Healthy China 2030" strategy [1]. Group 2: Key Contributions and Insights - Key figures emphasized the need for social participation in oral health initiatives, advocating for innovative methods to disseminate oral health knowledge to the public [2]. - The importance of integrating oral health education with youth development was highlighted, stressing the long-term benefits of instilling good oral hygiene habits from a young age [2]. - The China Oral Cleaning and Care Products Industry Association summarized the achievements of the "China Oral New Health Action," noting widespread recognition of the health concept "Brush One More Time, Health One More Point" and the successful dissemination of educational content through AI [2][3]. Group 3: Industry Perspectives - Representatives from leading oral health companies shared their experiences, focusing on professional oral care systems, AI innovations, and the importance of consumer engagement through brand revitalization [3]. - The "China Oral New Health Action · Ziyang Plan" was introduced, emphasizing the integration of oral health with regional industrial development and public well-being [3]. Group 4: White Paper Release - The event included the release of the "China Oral New Health Action" 2025 White Paper, outlining a comprehensive plan for oral health that spans policy guidance, technological innovation, and public engagement [4]. - The white paper aims to enhance public awareness and habits regarding oral health, positioning it as a crucial component of the broader health initiative in China [7].

Core Viewpoint - The article emphasizes the connection between oral health and overall health, highlighting the importance of dietary management in preventing both oral diseases and chronic conditions such as obesity and diabetes [1][2]. Group 1: Dietary Recommendations - The theme for this year's "National Love Your Teeth Day" is "Oral Health is Whole Body Health," with a sub-theme focusing on "Reducing Sugar, Controlling Weight, Protecting Teeth, Promoting Health" [1]. - It is recommended to limit the intake of free sugars to no more than 50 grams per day, ideally below 25 grams, and to avoid free sugar consumption for children under 2 years old [2]. - The article suggests replacing high-sugar snacks with high-fiber and high-protein foods to enhance satiety and reduce the risk of obesity [2][3]. Group 2: Oral Health Practices - To prevent dental erosion and cavities, it is advised to use straws when consuming sugary or acidic beverages to minimize contact with teeth [3]. - Regular oral health check-ups are recommended, with at least one check-up per year for the general population and every six months for children, as oral diseases often progress slowly and may not show early symptoms [3].

Core Viewpoint - The relationship between diet and oral health is significant, with dietary choices impacting both oral and overall health, especially in the context of the upcoming "National Love Your Teeth Day" [1] Group 1: Impact of Diet on Oral Health - Nutritional elements such as calcium, phosphorus, and vitamins are essential for the development and repair of teeth and periodontal tissues, promoting oral health [1] - Chewing food not only helps in mechanically cleaning teeth but also stimulates saliva production, which aids in oral self-cleaning [1] Group 2: Dangers of Unhealthy Diets - High-sugar diets increase sugar levels around teeth, leading to acid production by bacteria that can dissolve enamel and create cavities [2] - The transformation of fruit sugars into free sugars through juicing increases their cariogenic potential, posing a greater risk to dental health [2] Group 3: Connection Between Oral Health and Overall Health - There is a bidirectional relationship between periodontal disease and diabetes, where inflammation from periodontal disease can worsen insulin resistance and complicate blood sugar control [4] - Oral diseases can lead to systemic issues, including increased risks of atherosclerosis, coronary heart disease, myocardial infarction, and stroke due to the spread of pathogens through the bloodstream [4] Group 4: Recommendations for Promoting Oral Health - Experts recommend a "three-reduction" principle: reduce added sugars in cooking, decrease personal sugar intake, and lower the frequency of consuming sugary foods, along with rinsing the mouth after consuming such foods [4] - Older adults should focus on a balanced diet, ensure adequate nutrient intake, and avoid hard foods to maintain oral health [4]

Core Viewpoint - The article emphasizes the importance of oral health as a crucial component of overall health, highlighting the necessity of regular dental check-ups and treatments such as teeth cleaning and orthodontics to maintain dental hygiene and prevent further complications [1][2][3]. Group 1: Importance of Regular Dental Care - Regular dental cleaning is essential to remove plaque and tartar, which can lead to various dental diseases if not addressed [2][3]. - Recommendations for cleaning frequency include every six months to a year for healthy individuals, and every three to six months for those with periodontal disease [2]. - The use of electric toothbrushes can enhance brushing efficiency, particularly for individuals with limited hand mobility [2]. Group 2: Orthodontic Treatment - Various dental issues warrant orthodontic treatment, including misaligned teeth, large gaps, deep bites, and other malocclusions [3][4]. - Preparation for orthodontic treatment involves a thorough examination by a professional orthodontist, including X-rays and dental scans [4]. - Two main types of orthodontic devices are discussed: removable and fixed braces, each with its own advantages and disadvantages [4][5]. Group 3: Dental Implants - Missing teeth can lead to significant functional and aesthetic issues, making dental implants a viable solution [7][8]. - Dental implants involve placing a titanium root in the jawbone, which integrates with the bone over time, providing a stable foundation for artificial teeth [7][8]. - Candidates for dental implants should be in good health and have adequate bone structure, while certain health conditions may require further evaluation before proceeding [8].

Core Viewpoint - Oral health is a crucial component of overall health, and there are various behaviors that can harm teeth, necessitating scientific dental care practices [1] Group 1: Harmful Behaviors - Frequent consumption of sugary drinks can lead to tooth decay as sugars are broken down by bacteria, producing organic acids that demineralize tooth enamel [3] - Biting hard objects can cause tooth mobility and cracks, leading to complex dental issues [4] - Alternating between hot and cold stimuli can increase tooth sensitivity, affecting overall dental health [4] - Incorrect brushing habits, such as using excessive force or hard-bristled brushes, can wear down tooth enamel and lead to gum issues [4] Group 2: Recommended Dental Care Practices - Limit sugar and acidic food intake, and rinse with water after consuming sugary items to protect teeth [6] - Brush teeth at least twice daily for 2-3 minutes, avoiding aggressive brushing techniques [8] - Choose appropriate toothpaste based on dental conditions, such as fluoride toothpaste for cavity prevention or sensitivity toothpaste for sensitive teeth [8] - Use dental floss or interdental brushes to clean between teeth, as cavities often occur in these areas [10] - Regular dental cleanings are recommended, ideally every six months to a year, to prevent periodontal disease [11] - Timely extraction of problematic teeth is essential to avoid complications such as pain and infection [13]