内容概况：细胞计数仪作为生命科学研究和生物制造的基础性工具，2024年，中国细胞计数仪行业市场 规模约为112.37亿元，同比增长6.30%。技术方面，传统的、操作繁琐的手动或半自动计数设备（如血 球计数板）正迅速被淘汰。在研发端，细胞与基因治疗、生物药研发等前沿领域对细胞活性、粒径分 布、生长动态等多维度参数的监控提出了更高要求，驱动了对可进行活细胞监测、具备荧光分析能力的 多功能智能细胞分析仪的需求。 相关上市企业：迈瑞医疗（300760） 相关企业：浙江水晶光电科技股份有限公司、武汉锐科光纤激光技术股份有限公司、大族激光科技产业 集团股份有限公司、京东方科技集团股份有限公司、歌尔股份有限公司、韦尔半导体股份有限公司、歌 尔微电子股份有限公司、汉威科技集团股份有限公司、长飞光纤光缆股份有限公司、沐曦集成电路（上 海）股份有限公司、晶晨半导体（上海）股份有限公司、江苏恒瑞医药股份有限公司 关键词：细胞计数仪、细胞计数仪市场规模、细胞计数仪行业现状、细胞计数仪发展趋势 一、行业概述 细胞计数仪是一种用于精确测定液体样本中细胞数量，并可分析细胞特性（如活性、大小、形态、荧光 标记等）的实验室设备。其核心功能是通 ...

◎邱思雨 记者 操子怡 从复旦大学毕业后，裘霁宛便一头扎进生物药研发领域深耕几十年，积累了扎实的技术，拥有对行业的 深刻洞察。他创办的荃信生物在短短十年间，就成长为具有完整自主创新能力的国家级高新技术企业， 拥有及申报国内外发明专利百余项，在自身免疫病领域闯出了自己的一片天地。 更让人印象深刻的，是荃信生物写在公司文化里的使命和价值观——"追求科学创新，提供可负担的优 质疗法""用我们的努力，实现自我价值，创造社会福祉"。 "我们想把生物药这只'堂前燕'送到寻常百姓家，满足普通百姓的需求。"荃信生物董事会秘书胡衍保向 上海证券报记者表示，"当市场需求被充分激活，产品销量和销售额自然会提升，企业利润也会随之增 长，这是一个多方共赢的良性循环。" QX005N是荃信生物自主研发的，以IL-4Rα为靶点的创新型人源化单克隆抗体，目前已在国内拿下7项 IND许可，适应症覆盖成人和青少年中重度特应性皮炎、结节性痒疹及慢性鼻窦炎伴鼻息肉等。 "IL-4Rα赛道潜力巨大，但竞争也相对激烈，布局的企业不在少数。"胡衍保坦言，为了突出优势，公司 做了两件关键事：一是锚定差异化适应症研发药品；二是借力华东医药的渠道优势。 "为最 ...

Core Insights - Jiangsu Province's Science and Technology Department has announced the first batch of major provincial science and technology projects for 2025, focusing on "Innovative Biopharmaceuticals" [1] - Suzhou leads the province with 11 selected projects, accounting for 58% of the total proposed projects, highlighting its strength and innovation in the biopharmaceutical sector [1] Project Distribution - The selected projects in Suzhou show a significant concentration, with 8 projects from Suzhou Industrial Park, and 1 each from Zhangjiagang, Suzhou High-tech Zone, and Suzhou University, indicating a cluster advantage in the biopharmaceutical industry [1] - Research directions include cancer treatment, neurological diseases, infection control, innovative drug delivery, and core industrial equipment, aiming to address clinical treatment challenges and industry development bottlenecks [1] Focus on Clinical Needs - Several projects target unmet clinical needs, focusing on cutting-edge therapies, such as the development of "safe and efficient personalized mRNA tumor vaccines" and "targeted KRAS mutation-enhanced TCR-T cell therapy drugs," providing new treatment solutions for malignant tumors, neurodegenerative diseases, and infectious diseases [1] Technological Advancements - Projects like "novel inhalation delivery system for nucleic acid drugs targeting major lung diseases" and "efficient and precise targeted nucleic acid delivery platform technology development" focus on enhancing the efficiency and industrialization of biopharmaceutical R&D across the entire drug development chain [2] - Significant progress has been made in key equipment and platform construction for biopharmaceutical R&D, with projects such as "AI-assisted design of new biopharmaceutical chromatography consumables and big data platform for separation and purification" and "high-parameter high-purity spectral flow cytometry analysis and sorting instruments" aimed at achieving self-controllable core R&D equipment and materials [2] Recognition and Future Potential - The outstanding performance of Suzhou in the provincial science and technology major projects reflects a high recognition of its current biopharmaceutical R&D capabilities and showcases its immense innovation potential in cutting-edge biopharmaceutical technologies [2] - The implementation and advancement of these projects are expected to significantly promote innovation breakthroughs and clinical transformation processes in biopharmaceutical technologies, continuously injecting new momentum into the treatment of major diseases and the development of the biopharmaceutical industry [2]

Core Viewpoint - The company, Baillie Tianheng, has received formal approval from the National Medical Products Administration (NMPA) for the clinical trial of its innovative biopharmaceutical, BL-M24D1, which is an antibody-drug conjugate (ADC) targeting relapsed or refractory hematologic malignancies and advanced solid tumors [1] Group 1 - The clinical trial approval is for the company's self-developed ADC drug, BL-M24D1, which is linked to a new generation toxin [1] - BL-M24D1 shares the same "linker + toxin" platform with other ADC drugs, BL-B16D1 and BL-M17D1, developed from the same small molecule technology platform [1] - The indications for BL-M24D1 include treatment for relapsed or refractory hematologic malignancies and advanced solid tumors [1]

Core Viewpoint - The company, Xinlitai (002294.SZ), has announced that its subsidiary, Xinlitai (Suzhou) Pharmaceutical Co., Ltd., has received acceptance for the market application of its self-developed Class 1 biological drug, "Taikasi Monoclonal Antibody Injection," from the National Medical Products Administration. The intended indications for this drug are hypercholesterolemia and mixed dyslipidemia [1]. Summary by Categories Company Developments - Xinlitai has successfully submitted a market application for its new biological drug, indicating progress in its research and development efforts [1]. Product Information - The drug "Taikasi Monoclonal Antibody Injection" targets high cholesterol levels and mixed lipid disorders, which are significant health concerns [1].

Core Viewpoint - The company reported a mixed financial performance for the first half of 2025, with a slight decline in revenue but an increase in net profit, indicating potential resilience in profitability despite revenue challenges [1][2]. Financial Performance - In H1 2025, the company achieved revenue of 4.288 billion yuan, a year-on-year decrease of 1.91%, while net profit attributable to shareholders was 775 million yuan, a year-on-year increase of 16.97% [1]. - For Q2 2025, revenue was 2.233 billion yuan, down 3.86% year-on-year, but net profit rose to 460 million yuan, up 25.41% year-on-year [1]. - The overall gross margin for H1 2025 was 67.37%, a slight decrease of 0.08 percentage points year-on-year, with a net profit margin of 18.42%, an increase of 3.48 percentage points year-on-year [1]. Dividend and Shareholder Returns - The company announced a mid-year dividend payout of 2.1 yuan per share (before tax), representing 40.50% of the net profit attributable to shareholders for H1 2025 [1]. Business Development and Strategy - The company successfully completed the "100-day integration" with its controlling shareholder, China Resources Sanjiu, enhancing marketing capabilities and business synergy [2]. - The company is focusing on expanding its pharmaceutical commercial sector and leveraging China Resources Sanjiu's marketing channels to boost sales in the second half of the year [2]. Research and Innovation - The company has 83 projects in its research pipeline, including 31 innovative drugs, and is advancing its modern traditional Chinese medicine initiatives [2]. - The company is also focusing on biopharmaceuticals, with ongoing clinical trials for several innovative therapies [2]. Investment Outlook - The investment rating is maintained at "Buy," with expectations for net profit growth from 1.19 billion yuan in 2025 to 1.51 billion yuan in 2027, reflecting a compound annual growth rate [3].

Core Viewpoint - The company, Sinocelltech Group Limited, is preparing for a specific issuance of A-shares in 2025, aiming to raise up to 900 million RMB to enhance its liquidity and support its ongoing research and development in the biopharmaceutical sector [1][18][24]. Company Overview - Sinocelltech Group Limited was established on April 23, 2007, and became a joint-stock company on March 19, 2019, with a registered capital of 445.34 million RMB [2][3]. - The company focuses on the research and development of innovative biopharmaceuticals, particularly in the treatment of malignant tumors, autoimmune diseases, infectious diseases, and genetic disorders [3][4]. Business Operations - The company has developed a high-efficiency, high-throughput technology platform for biopharmaceutical research and production, with a diverse pipeline including monoclonal antibodies, recombinant proteins, and innovative vaccines [3][4][5]. - As of the date of the report, the company has one recombinant protein drug and four antibody drugs approved for market, with three vaccine products included for emergency use, and several others in clinical research [3][7]. Financial Performance - The company reported revenues of 102.32 million RMB, 188.73 million RMB, and 251.27 million RMB for the years 2022, 2023, and 2024 respectively, indicating a significant growth trajectory [7][8]. - The total assets as of December 31, 2024, were approximately 344.96 million RMB, with total liabilities of about 325.11 million RMB, resulting in shareholders' equity of 19.85 million RMB [8][9]. Issuance Details - The upcoming issuance will involve the sale of up to 25 million shares at a price of 36.00 RMB per share, which is not less than 80% of the average trading price over the 20 trading days prior to the pricing date [17][18]. - The funds raised will be used entirely to supplement the company's working capital [18][24]. Regulatory Compliance - The company has undergone due diligence and has been deemed compliant with relevant laws and regulations governing securities issuance and listing [22][24]. - The issuance is subject to approval from the Shanghai Stock Exchange and the China Securities Regulatory Commission [24].

Core Viewpoint - Shanghai OPM Biosciences Co., Ltd. reported significant growth in revenue and net profit for the first half of 2025, driven by strong market demand and effective cost management [1][6][7]. Financial Performance - The company achieved operating revenue of RMB 177.75 million, a year-on-year increase of 23.77% compared to RMB 143.61 million in the same period last year [6][7]. - Total profit reached RMB 48.85 million, marking a 62.55% increase from RMB 30.05 million in the previous year [6][7]. - Net profit attributable to shareholders was RMB 37.55 million, up 55.55% from RMB 24.14 million in the prior year [6][7]. - The net cash flow from operating activities surged to RMB 61.34 million, a remarkable increase of 271.78% compared to RMB 16.50 million in the same period last year [6][7]. Key Financial Indicators - Basic earnings per share rose to RMB 0.33, reflecting a 57.14% increase from RMB 0.21 in the previous year [7]. - The weighted average return on net assets increased to 1.78%, up from 1.13% [7]. - Research and development expenses accounted for 13.58% of operating revenue, compared to 10.71% in the previous year [7]. Business Development - The company has expanded its product offerings, with 282 confirmed drug development pipelines utilizing its cell culture products, an increase of 35 from the end of 2024 [6][7]. - Service business revenue also improved, showing a growth of 13.24% compared to the previous year [6][7]. Shareholder Returns - The company proposed a cash dividend of RMB 2.30 per 10 shares, contingent on meeting profit distribution conditions for the first half of 2025 [1].

Core Viewpoint - The announcement of an exclusive supply agreement between Sichuan Luzhou Bichang Biopharmaceutical Co., Ltd. and GOODFELLOW PHARMACORPORATION marks a significant step for the company in entering the Philippine market and expanding its international presence, particularly in the Southeast Asian region [1][6]. Group 1: Product and Market Overview - Efparepoetin alfa is an innovative biopharmaceutical product designed to treat anemia in adult dialysis patients caused by chronic kidney disease (CKD), filling a market gap as no similar products have been approved in China [2][3]. - The global chronic kidney disease market is projected to reach USD 41.21 billion in 2024 and USD 43.16 billion in 2025, with a compound annual growth rate (CAGR) of 5.9%, driven by factors such as aging population and increasing diabetes and hypertension cases [3]. Group 2: Strategic Development - The company is focusing on "innovation-driven, diversified development" by strengthening its biopharmaceutical sector while maintaining its leadership in traditional Chinese medicine, with 12 biopharmaceutical products currently in the R&D phase [4]. - The Chinese biopharmaceutical market is expected to exceed RMB 800 billion by 2025, benefiting from policy support and technological innovation, which aligns with the company's strategic direction [4]. Group 3: Financial Performance and Social Responsibility - Since its listing in 2016, the company has returned over RMB 9.183 billion to shareholders through cash dividends and share buybacks, significantly exceeding the initial fundraising of RMB 3.9 billion [5]. - The company has contributed over RMB 32 billion in taxes, supporting local public services and promoting employment through its production and R&D centers across various provinces [5]. Group 4: Future Outlook - The collaboration with GOODFELLOW is seen as a strategic move to capitalize on the growing demand in emerging markets, positioning the company for future internationalization of more products [6]. - The integration of technological innovation, stable capital operations, and social responsibility is expected to create a sustainable competitive advantage for the company in the global pharmaceutical market [6].

Core Viewpoint - Shenzhou Cell (688520.SH) has achieved its first profit in 2024 and plans to raise up to 900 million yuan through a private placement to its controlling shareholder, Lhasa Ailike, to enhance liquidity and reduce financial risks [2][6][9] Group 1: Fundraising and Shareholding Structure - Shenzhou Cell plans to issue shares at 36 yuan per share, raising no more than 900 million yuan, which will be used entirely for replenishing working capital [3][4] - After the issuance, Lhasa Ailike's direct shareholding in Shenzhou Cell will increase to 62.98%, while the total control by its actual controller, Xie Liangzhi, and his concerted parties will rise to 70.86% [4][6] - This is the second time Shenzhou Cell has planned a private placement since its IPO, with the first occurring in June 2020, raising 1.282 billion yuan [5] Group 2: Financial Performance and Profitability - In 2024, Shenzhou Cell achieved revenue of 2.513 billion yuan, a year-on-year increase of 33.13%, and a net profit of 112 million yuan, up 128.27% [2][7] - The company’s R&D expenditure in 2024 was 936 million yuan, accounting for 37.25% of its revenue, reflecting a 23.11% decrease from the previous year [9] - Shenzhou Cell's cumulative losses reached 3.76 billion yuan by March 2025, with a debt ratio of 94.25%, indicating a need for capital and operational funding [9] Group 3: Product Development and Market Strategy - Shenzhou Cell focuses on developing biopharmaceutical products for various diseases, including cancer and autoimmune diseases, and has seen a stable sales increase of its core product, Anjain, which generated 1.89 billion yuan in sales in 2024 [6][7] - The sales of three other products, Anpingxi, Anjairun, and Anbeizhu, exceeded 620 million yuan in 2024, marking a significant year-on-year growth of 499.80% [8] - The company has implemented effective market strategies to ensure stable revenue growth despite pricing pressures from regional procurement [7][8]