作为聚乙二醇蛋白质长效药物领域的龙头，特宝生物的业绩表现十分亮眼。2016-2024年间，公司营业 收入从2.8亿元增长至28亿元，营业利润从0.3亿元增长至9.7亿元。2025年前三季度公司营业收入同比增 长26.85%，营业利润同比增长16.11%，归母净利润同比提升20.21%。 文 | 财经思享汇，作者 | 王璇，编辑 | 管东生 2025年10月，派格宾新增"联合核苷（酸）类似物用于成人慢性乙型肝炎患者的HBsAg持续清除"适应 症，成为全球首个获批该适应症的药物，标志着乙肝临床治愈成为现实，实现这一突破的公司正是特宝 生物（688278.SH）。 图 公司营业总收入、营业利润、归母净利润情况 为股东创造财富的效率同样突出，自2019年以来，公司净资产收益率一直保持在10%以上，并呈现逐年 增长的趋势，而资产负债率并不高，截至2025年前三季度仅为20.52%。 公司业绩增长背后的核心动力是什么？这样的增长还能持续多久？ 大单品护城河 公司现有产品包含三个板块，分别为抗病毒用药（派格宾）、血液/肿瘤用药（珮金、特尔立、特尔 津、特尔康）、内分泌用药（益佩生）。其中，派格宾作为核心大单品，占到公司20 ...

Investment Rating - The investment rating for the company is "Outperform the Market" [5][15] Core Insights - The core product, Pegb interferon α-2b injection (brand name: Pegbin), has received approval for a new indication for functional cure of chronic hepatitis B, which is expected to enhance its market position [2][3] - The company reported a revenue of 2.48 billion yuan in the first three quarters of 2025, representing a year-on-year growth of 26.9%, and a net profit of 666 million yuan, up 20.2% [1][8] - The approval of Pegbin is based on clinical trial results showing that 31.4% of patients achieved HBsAg seroclearance and sustained HBV DNA suppression after treatment [2][3] Financial Performance - For the first three quarters of 2025, the company achieved quarterly revenues of 673 million yuan, 837 million yuan, and 969 million yuan, with year-on-year growth rates of 23.5%, 29.9%, and 26.7% respectively [1][8] - The net profit for the same period was 182 million yuan, 246 million yuan, and 238 million yuan, with year-on-year growth rates of 41.4%, 40.0%, and -4.6% respectively [1][8] - The gross margin for the first three quarters of 2025 was 92.6%, with a net margin of 26.9% [9] Revenue and Profit Forecast - The company forecasts revenues of 3.77 billion yuan, 4.96 billion yuan, and 6.40 billion yuan for 2025, 2026, and 2027 respectively, with corresponding net profits of 1.07 billion yuan, 1.54 billion yuan, and 2.17 billion yuan [4][18] - The projected PE ratios for 2025, 2026, and 2027 are 29x, 20x, and 14x respectively [3][15] Market Position and Product Development - Pegbin is currently the only long-acting interferon product in China, and the company is expected to benefit from the growing patient population with chronic hepatitis B [3][15] - The approval of long-acting growth hormone further enhances the company's product portfolio, which is anticipated to contribute to sales growth [3][15]

Core Insights - The article highlights the transformation of the Xiamen Biopharmaceutical Port and the success story of Teva Biopharma, which has evolved from a small team to a leading company in the biopharmaceutical industry in China [1][2]. Company Overview - Teva Biopharma, established in 1996, focuses on the research, production, and sales of recombinant proteins and long-acting modified drugs, primarily in the field of immunology [2]. - The company has developed several first-class new drugs, including Pegfilgrastim, Yipeng, and Peijin, based on its innovative platform technology centered around polyethylene glycol long-acting drugs [2]. Financial Performance - From 2018 to 2024, Teva Biopharma's operating revenue increased from 448 million to 2.817 billion, while net profit rose from 16 million to 827 million [2]. - In the first half of 2025, the company reported R&D expenditures of 202 million, reflecting a year-on-year growth of 48.77% [3]. Innovation and Development - Teva Biopharma emphasizes continuous innovation, with a focus on building a core technology platform that includes PEG modification, drug production, and optimization [4]. - The company has transitioned from a small team of 7 to over 2,000 employees and successfully listed on the STAR Market in January 2020, marking a significant milestone in its development [4]. Future Outlook - The company views innovation as its greatest opportunity and recognizes the risk of losing direction in the innovation process [5]. - Teva Biopharma aims to shift from single drug development to integrated innovation through multi-path technology, addressing complex diseases and enhancing clinical efficacy and value [5].

Core Insights - The article highlights that only 13 women globally have become billionaires by founding healthcare companies, with 7 of them from China, indicating a significant presence of Chinese female entrepreneurs in the healthcare sector [1][3]. Industry Overview - The Chinese biopharmaceutical industry is experiencing a transformative phase, referred to as the "DeepSeek moment," as it evolves from being a "generic drug powerhouse" to a competitive force against Western innovation in pharmaceuticals [2]. - In 2024, over 1,250 new drug candidates are expected to enter the research and development phase in China, surpassing the European Union and nearly matching the United States' 1,440 candidates [2]. - Nearly one-third of the drug candidates licensed by large pharmaceutical companies in 2024 are from Chinese firms, a significant increase from zero in 2019 [3]. Company Highlights - **Hansoh Pharmaceutical Group**: Founded by Zhong Huijuan, the company reported a total revenue of approximately 12.26 billion yuan in 2024, with a year-on-year growth of about 21.3% [7]. - **Aimeike**: Founded by Jian Jun, the company specializes in hyaluronic acid production and was listed on the A-share market in 2020, achieving a market value exceeding 170 billion yuan [10]. - **Qizheng Tibetan Medicine**: Founded by Lei Jufang, the company generated sales revenue of 1.655 billion yuan in 2024, with a year-on-year growth of 16.31% [14]. - **Haisco Pharmaceutical Group**: Co-founded by Fan Xiulian, the company reported a revenue of 3.721 billion yuan in 2024, with a year-on-year increase of 10.92% [17]. - **Teva Biopharmaceuticals**: Founded by Yang Ying, the company has shown rapid growth, with revenues increasing from 1.527 billion yuan in 2022 to 2.817 billion yuan in 2024 [18]. - **Kangfang Biopharmaceutical**: Founded by Xia Yu, the company has developed several innovative drugs and is recognized for its leading position in the biopharmaceutical sector [23]. - **Xinlitai**: Co-founded by Liao Qingqing, the company has shifted focus to self-research and development, achieving a revenue of 4.012 billion yuan in 2024, with a year-on-year growth of 19.22% [26].

Core Viewpoint - Teabo Bio's performance continues to grow significantly in the hepatitis B field, with a strong increase in revenue and net profit in Q1 2025 compared to the previous year [1][2]. Financial Performance - In Q1 2025, Teabo Bio achieved revenue of 673 million yuan, a year-on-year increase of 23.48%, and a net profit of 182 million yuan, up 41.4% [1]. - From 2020 to 2024, the company's revenue grew from 794 million yuan to 2.817 billion yuan, while net profit increased from 117 million yuan to 828 million yuan [2]. - The company has maintained a continuous dual increase in revenue and net profit for seven consecutive years, with a cumulative net profit of 1.968 billion yuan since its IPO [2]. Product Development - The growth in performance is attributed to the stable sales of the key product, Peginterferon, which is a first-in-class drug with complete independent intellectual property rights [2]. - Teabo Bio has invested significantly in R&D, with expenditures rising from 76.68 million yuan in 2020 to 295 million yuan in 2024, totaling 833 million yuan over the five years [2]. Intellectual Property and Market Position - As of the end of 2024, Teabo Bio has obtained 16 invention patents and a total of 293 intellectual property rights [3]. - The company has made important progress in multiple R&D projects, including the acceptance of a drug registration application for its self-developed growth hormone injection in January 2024 [3]. Stock Performance - Teabo Bio's stock price has seen a significant increase, rising from an IPO price of 8.24 yuan per share to 78.96 yuan per share as of April 22, representing a cumulative increase of 858.25% [3].