8月27日，华东医药盘中下跌2.01%，截至13:54，报44.80元/股，成交4.18亿元，换手率0.53%，总市值 785.83亿元。 资金流向方面，主力资金净流出3710.20万元，特大单买入1409.71万元，占比3.38%，卖出2374.86万 元，占比5.69%；大单买入7233.85万元，占比17.33%，卖出9978.90万元，占比23.90%。 华东医药今年以来股价涨31.69%，近5个交易日跌2.18%，近20日跌0.18%，近60日涨1.73%。 截至6月30日，华东医药股东户数6.98万，较上期减少7.91%；人均流通股25083股，较上期增加8.59%。 2025年1月-6月，华东医药实现营业收入216.75亿元，同比增长3.39%；归母净利润18.15亿元，同比增长 7.01%。 分红方面，华东医药A股上市后累计派现82.59亿元。近三年，累计派现31.58亿元。 机构持仓方面，截止2025年6月30日，华东医药十大流通股东中，香港中央结算有限公司位居第三大流 通股东，持股3983.84万股，相比上期减少628.25万股。中欧医疗健康混合A（003095）位居第四大流通 股东，持股 ...

2025 年 08 月 25 日 佐力药业(300181.SZ) 2025H1 利润端表现强劲，C 端拓展与产 股价表现 资料来源：Wind 资讯 升幅% 1M 3M 12M 相对收益 1.2 9.6 2.4 绝对收益 7.5 21.4 34.6 李奔 分析师 SAC 执业证书编号：S1450523110001 liben@essence.com.cn 冯俊曦 分析师 SAC 执业证书编号：S1450520010002 fengjx@essence.com.cn 胡雨晴 分析师 SAC 执业证书编号：S1450524080002 huyq4@essence.com.cn 相关报告 乌灵胶囊通过集采快速放 量，经营性现金流大幅增长 2024-07-30 乌灵系列市场空间广阔，百 令胶囊上市放量可期 2024-04-19 -20% -10% 0% 10% 20% 30% 40% 2024-08 2024-12 2025-04 2025-08 佐力药业 沪深300 品研发可期 事件：公司发布 2025 年中报。 2025 年上半年公司实现营业收入 15.99 亿元，同比增长 11.99%；实 现归母净利润 3.74 ...

Industry Overview - The pharmaceutical industry is experiencing steady growth, driven by core products and strategic market expansions [3][4]. Company Performance - The company reported a revenue of 1.599 billion yuan for H1 2025, an increase of 11.99% year-on-year, and a net profit of 374 million yuan, up 26.16% year-on-year [4][5]. - The gross margin was 63.01%, reflecting a year-on-year increase of 0.39 percentage points, while the net margin reached 23.71%, up 2.72 percentage points [4]. Core Product Growth - The core products, including the Wuling series and Bailing series, have shown robust growth, with Wuling series sales reaching 897 million yuan (up 7.23%) and Bailing series sales at 113 million yuan (up 38.51%) [5][6]. Strategic Initiatives - The company is implementing a "one body, two wings" strategy, focusing on marketing and R&D to enhance operational performance [6]. - The company is expanding its C-end business by launching larger packaging for Wuling capsules and forming strategic partnerships with major chains [6]. Clinical Validation and R&D Progress - The core product Wuling capsules have received validation from international journals, confirming their safety and efficacy in treating mild depression in Parkinson's patients [7]. - The company has made significant progress in clinical trials, with multiple products entering various stages of development [7]. Profit Forecast - The company is expected to achieve revenues of 3.231 billion yuan, 3.687 billion yuan, and 4.265 billion yuan for 2025, 2026, and 2027, respectively, with year-on-year growth rates of 25.4%, 14.1%, and 15.7% [8]. - Net profits are projected to be 661 million yuan, 839 million yuan, and 986 million yuan for the same years, with growth rates of 30.2%, 26.9%, and 17.4% [8][9].

Investment Rating - The investment rating for the company is "Buy" and is maintained [6]. Core Views - The company reported a revenue of 1.599 billion yuan for the first half of 2025, representing a year-on-year growth of 11.99%. The net profit attributable to shareholders was 374 million yuan, up 26.16% year-on-year, while the net profit after deducting non-recurring gains and losses was 372 million yuan, reflecting a growth of 27.24% year-on-year [2][4]. - In Q2 2025, the company achieved a revenue of 775 million yuan, which is a 2.60% increase year-on-year. The net profit attributable to shareholders for this quarter was 192 million yuan, showing a year-on-year growth of 25.20%, and the net profit after deducting non-recurring gains and losses was 190 million yuan, up 28.30% year-on-year [2][4]. Financial Performance - The company’s core products, including the Wuling series and the Bailing series, have shown significant growth, with increases of 7.23%, 38.51%, and 56.60% respectively in H1 2025, contributing to the overall revenue growth [10]. - The gross profit margin for H1 2025 was 63.01%, an increase of 0.39 percentage points year-on-year, while the net profit margin was 23.35%, up 2.62 percentage points year-on-year [10]. - The company’s sales expenses were 500 million yuan, a year-on-year increase of 2.31%, with a sales expense ratio of 31.23%, down 2.96 percentage points year-on-year. Management expenses decreased by 9.15% year-on-year to 49 million yuan, with a management expense ratio of 3.03% [10]. Future Outlook - The company expects to achieve net profits of 660 million yuan, 845 million yuan, and 1.084 billion yuan for the years 2025, 2026, and 2027 respectively, with corresponding earnings per share (EPS) of 0.94 yuan, 1.21 yuan, and 1.55 yuan [10].

Core Viewpoint - Zhaoli Pharmaceutical (300181.SZ) has demonstrated strong profitability with a cumulative return of 154.14% over three years, despite a generally lackluster performance in the traditional Chinese medicine sector [1] Financial Performance - The company's net profit attributable to shareholders increased from 25.59 million yuan in 2019 to 508 million yuan in 2024 [1] - The gross profit margin for Zhaoli Pharmaceutical has decreased from 71.43% in 2021 to 60.95% currently, a decline of approximately 10 percentage points [7] Key Products - Zhaoli Pharmaceutical specializes in traditional Chinese medicine products, with its flagship product, Wuling Capsule, generating 1.438 billion yuan in revenue in 2024, accounting for 55.79% of total revenue [3] - Wuling Capsule, used for treating insomnia, is a 1 billion yuan-level product with a stable gross profit margin exceeding 80% [4][5] Market Position and Competitive Advantage - Wuling Capsule benefits from unique barriers to entry, including proprietary technology and its inclusion in the National Essential Medicines List, which limits competition and maintains pricing power [3][5] - The company has successfully increased the packaging size of Wuling Capsule to enhance sales and reduce marginal costs [5] Strategic Focus - Zhaoli Pharmaceutical is committed to its core business of traditional Chinese medicine while expanding into the rapidly growing market for traditional Chinese medicine pieces and granules [11] - The company aims to develop its Bailing series products into a 1 billion yuan-level product by 2025, despite facing competition from established players [12] Sales Channels and Growth Strategy - The company is shifting its sales strategy from primarily hospital sales to a more consumer-oriented approach, targeting online retail and chain pharmacies to tap into the broader health market [13]

Core Viewpoint - Huadong Medicine's stock price experienced a decline of 1.32% on August 8, closing at 42.47 yuan, with a trading volume of 355 million yuan [1] Company Overview - Huadong Medicine operates in three main sectors: pharmaceutical manufacturing, pharmaceutical commerce, and medical aesthetics [1] - The company's core products include Bailin capsules and Indomethacin tablets, with a focus on oncology, diabetes, and immunosuppressants [1] - The wholly-owned subsidiary, Sino-American Huadong, holds a patent for the crystal form of Indomethacin tablets, which is protected until 2040 [1] Recent Developments - Sino-American Huadong is actively defending its patent rights for Indomethacin tablets, resulting in seven pharmaceutical companies being suspended from purchasing the product due to patent disputes [1] - The National Intellectual Property Administration has ruled to maintain the validity of the involved patents against several invalidation requests [1] - Due to the patent disputes, Indomethacin tablets were not included in the 11th batch of national drug procurement [1] Financial Activity - On August 8, Huadong Medicine saw a net outflow of 4.4782 million yuan in principal funds, while the cumulative net inflow over the past five days reached 9.757 million yuan [1]

Group 1: Financial Performance - The company's revenue for the first half of 2025 is expected to grow by approximately 12% year-on-year, primarily due to a decline in sales of traditional Chinese medicine products compared to the previous year [1] - The net cash flow from operating activities is projected to be between 270 million and 290 million CNY, an improvement from 215.35 million CNY in the same period last year [3] Group 2: Cost Management - The company implements measures such as lean management, cost reduction, and comprehensive budget management to enhance expense control and improve efficiency [1] - Sales expense ratio is expected to fluctuate based on marketing strategies and product promotion, with a historical decline due to centralized procurement [2] Group 3: Market Expansion Strategies - The company plans to strengthen strategic partnerships with leading pharmacy chains and enhance patient education and promotion activities [4] - Digital marketing initiatives will be advanced through O2O strategies to capture the young consumer market [4] - Collaboration with Zhejiang University aims to develop innovative health products leveraging AI technology [5] Group 4: Research and Development - The company is focused on developing innovative traditional Chinese medicine, with several projects in clinical and preclinical stages [5] - Ongoing research includes secondary development of existing products and expanding indications for current medications [5]

Group 1: Product Overview - Wuling Capsule is a unique traditional Chinese medicine with high safety and clear efficacy, suitable for standalone use or in combination with other medications [1] - The current National Essential Medicines List (2018 version) includes 685 varieties, with 268 being traditional Chinese medicines [1] - The company is expanding the market application of Wuling Capsule to areas like Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) [2] Group 2: Research and Development Strategy - Future R&D will focus on proprietary compound preparations based on Wuling fungus powder, addressing unmet clinical needs and leveraging market demand [3] - The company aims to establish a reasonable layout for new drug development, with simultaneous projects in different stages: initiation, clinical trials, and market launch [3] Group 3: Financial Impact and Incentives - The stock incentive plan for 2025 involves share-based payment expenses of approximately 30 million yuan [4] Group 4: Health Sector Strategy - The company is pursuing a strategy termed "一路向 C" (Towards C-end), focusing on health products and leveraging its strengths in core hospital-end pharmaceuticals [5] - There is an emphasis on developing products that meet the growing health demands of the public [5] Group 5: Market Expansion Goals - The company aims to make the Bailin Capsule a 1 billion yuan product through accelerated sales efforts, with 26 provinces already issuing procurement execution notices for traditional Chinese medicine [5]

Investment Rating - The report maintains a "Buy" rating for the company [1]. Core Views - The company is undergoing a transformation towards innovation, with results expected to materialize soon. The impact of centralized procurement on existing generic and traditional Chinese medicine businesses is gradually diminishing, while the industrial microbiology and medical aesthetics segments are expected to contribute to revenue growth. Overall, the company's performance is projected to grow steadily, and the realization of innovation may lead to a revaluation of its value [7]. - The company has over 80 innovative drug candidates in its pipeline, focusing on endocrine, autoimmune, and oncology fields. The innovative products are expected to be launched and contribute to revenue starting in 2025, enhancing the sales system for innovative drugs [7]. - The industrial microbiology and medical aesthetics segments are forming a diversified growth engine. The company has established a strategic layout in industrial microbiology and is expected to achieve rapid growth as customer orders convert into production capacity. The medical aesthetics segment is also anticipated to recover quickly with the launch of new products [7]. Summary by Sections 1. Company Overview - Established in 1993, the company has developed into a large-scale comprehensive pharmaceutical enterprise covering the entire pharmaceutical industry chain, including pharmaceutical manufacturing, commercial distribution, medical aesthetics, and industrial microbiology [13]. - The company has shifted its focus from generic drug development to innovation-driven strategies since 2018, with a strong emphasis on endocrine, autoimmune, and oncology treatment areas [13]. 2. Financial Performance - The company's total revenue is projected to grow from 40,624 million in 2023 to 52,228 million in 2027, with a compound annual growth rate (CAGR) of 11.64% from 2010 to 2024. The net profit attributable to shareholders is expected to increase from 2,839 million in 2023 to 5,154 million in 2027 [1][20]. - The company's gross profit margin and net profit margin have improved, with gross profit margin rising from 24.27% in 2016 to 33.31% in 2024 [23]. 3. Innovation and R&D - The company has established a comprehensive drug research and development system, focusing on innovative drug candidates in the fields of oncology, endocrine, and autoimmune diseases. The R&D pipeline includes over 80 projects, with significant progress in clinical trials for several innovative products [26][32]. - The company has significantly increased its R&D investment, with the number of researchers growing from 550 in 2018 to 1,864 in 2024, and R&D expenditure rising from 707 million in 2018 to 1,770 million in 2023 [29]. 4. Market Position and Growth Potential - The company is well-positioned in the GLP-1 receptor agonist market, with several innovative products in various stages of clinical development. The global market for GLP-1 drugs is expected to grow significantly, providing a substantial opportunity for the company [39][46]. - The medical aesthetics segment is also expected to contribute to growth, with the company expanding its international and high-end product offerings [7].

Investment Rating - The investment rating for the company is "Buy" (maintained) [7] Core Views - The company is focusing on chronic diseases, tumors, and immunology, covering four major business segments: pharmaceutical manufacturing, pharmaceutical commerce, medical aesthetics, and industrial microbiology. It is continuously optimizing its product structure and transitioning from generics to innovation. The core products of its subsidiary, China Medical East, are maintaining stable market growth and increasing market share. The medical aesthetics segment is showing growth potential, and the innovative pipeline is entering a harvest period. The projected net profits for 2025-2027 are estimated at 40.61 billion, 47.16 billion, and 55.37 billion yuan, with corresponding EPS of 2.32, 2.69, and 3.16 yuan, leading to PE ratios of 16.3, 14.0, and 11.9 times, respectively [7][8][10]. Summary by Sections Company Overview - The company, established in 1993 and listed in 1999, has developed into a large comprehensive pharmaceutical company covering the entire pharmaceutical industry chain. It has transitioned towards a research and innovation-driven pharmaceutical enterprise since 2018 [18]. Business Performance - The company reported a revenue of 419.1 billion yuan in 2024, a year-on-year increase of 3.2%, and a net profit of 35.1 billion yuan, up 23.7% year-on-year. The pharmaceutical manufacturing segment generated 138.1 billion yuan in revenue, growing by 13.1%, while the medical aesthetics segment saw a slight decline in revenue [8][22]. Innovative Pipeline - The company is focusing on three core areas: oncology, endocrinology, and autoimmune diseases, with a differentiated layout in ADC and PROTAC technologies. The innovative pipeline includes over 80 projects, with several products entering clinical stages. The company is also actively pursuing collaborations and acquisitions to enhance its product offerings [9][39][55]. Financial Summary - The company’s financial metrics show steady growth, with projected revenues of 44.68 billion, 47.95 billion, and 51.83 billion yuan for 2025, 2026, and 2027, respectively. The gross margin is expected to improve from 33.6% in 2025 to 35.4% in 2027, while the net profit margin is projected to increase from 9.1% to 10.7% over the same period [10][28].