来源：人民日报健康客户端 春节聚会，推杯换盏、把酒言欢——热闹是真的，但身体在"悄悄加班"也是真的。你以为酒精只是伤 胃？错。医生警告：酒精的伤害，远比你想的更可怕。肝脏、心脏、大脑、血管……一杯酒下去，全身 都在替你扛。 今天这篇文章，并非劝你一定要戒酒，而是劝你再别用错方式饮酒，这6种喝法太伤身。 这6种喝酒方式，危害翻倍 各种酒混在一起喝，首先就会让我们不自觉地饮酒过量。而且，两种以上的酒混着喝还会表现出某 种"协同作用"，对人体伤害更大。长沙市中心医院重症医学科主任医师杨勇2024年在医院微信公众号刊 文介绍，不同种类的酒精饮品混合饮用会加速酒精的吸收，增加肝脏和胃肠的负担，从而显著提高急性 酒精中毒的风险。② 1. 服药期间喝酒 正在服用药物的人可千万不能因为"兴致"，而忽视了酒与药同服的危害。中南大学湘雅二医院药学部主 管药师席洋2023年在医院微信公众号刊文提醒，若服用与酒精有相互作用的药物，应停药后至少间隔7 天再饮酒。老年人、肝肾功能不全等特殊人群间隔时间应延长。此外，喝酒后建议在3天内避免服用与 酒精有相互作用的药物。① 除了头孢不能与酒同时服用，还有其他一些药物服药期间也不能饮酒： 镇静 ...

Core Viewpoint - The inflation rate in Macau for the year 2025 is projected to be 0.33%, with the Consumer Price Index (CPI) rising by 0.69% year-on-year in December 2025 and by 0.17% month-on-month [1]. Group 1: Yearly Inflation and Price Index Changes - The CPI for food and non-alcoholic beverages increased by 0.62% year-on-year, driven by higher costs for dining out, takeout, bread, and rice, while prices for fresh fish and pork decreased [1]. - The housing and fuel category saw a year-on-year increase of 0.25%, primarily due to rising housing rents, although lower electricity prices mitigated the overall increase [1]. - Significant year-on-year increases were observed in the recreation, sports, and culture category (+2.02%) and miscellaneous goods and services (+1.85%) [1]. - Conversely, categories such as information and communication (-2.82%), clothing (-1.88%), and transportation (-1.15%) experienced price declines [1]. - The average CPI for Class A and Class B goods rose by 0.28% and 0.37% year-on-year, respectively [1]. Group 2: Monthly Inflation and Price Index Changes - Compared to November 2025, the CPI increased by 0.17% in December, with transportation (+1.65%) and clothing (+0.97%) categories seeing price increases due to higher airfares and clothing prices [2]. - The tobacco and alcohol category saw a month-on-month decrease of -0.68% due to lower prices for alcoholic beverages, while food and non-alcoholic beverages recorded a slight decline of -0.03% due to falling vegetable prices [2]. - The average CPI for the fourth quarter of 2025 rose by 0.67% year-on-year, with Class A and Class B goods increasing by 0.61% and 0.72%, respectively [2]. - Compared to the third quarter of 2025, the average CPI increased by 0.27% [2].

Core Viewpoint - The article discusses the relationship between tumor markers and cancer, emphasizing that elevated tumor marker levels do not necessarily indicate cancer and can be influenced by various factors such as inflammation, infection, and diet [4][5]. Group 1: Understanding Tumor Markers - Tumor markers are substances produced by tumor cells or in response to tumor cells, primarily consisting of proteins, hormones, enzymes, and oncogene products [4]. - They can be found in cells, tissues, blood, or bodily fluids and require specific samples for detection through biochemical and immunological methods [4]. - Elevated tumor marker levels may indicate a potential association with tumors, but they are not definitive for cancer diagnosis [5]. Group 2: Common Tumor Markers and Associated Cancers - Common tumor markers include: - Alpha-fetoprotein (AFP): Indicates primary liver cancer [6] - Carcinoembryonic antigen (CEA): Indicates colorectal, gastric, and pancreatic cancers [6] - Cancer antigen 125 (CA125): Indicates ovarian cancer [6] - Cancer antigen 199 (CA199): Indicates pancreatic, hepatobiliary, and gastric cancers [6] - Prostate-specific antigen (PSA): Indicates prostate cancer [6] Group 3: Dietary Influences on Tumor Markers - Certain foods can temporarily elevate tumor marker levels and may increase cancer risk with long-term consumption [7]. - Processed meats, such as sausages and bacon, can cause transient increases in CEA levels due to chronic inflammation in the digestive tract [8]. - High sugar and refined carbohydrates can lead to increased insulin-like growth factor (IGF) secretion, potentially causing chronic inflammation and fluctuations in CA125 levels [10][11]. - High-purine foods, like organ meats and seafood, can elevate uric acid levels, leading to temporary fluctuations in CA199 [12]. - Alcohol consumption can increase liver burden, potentially causing mild elevations in AFP and affecting CA199 levels, with a higher risk of various cancers associated with frequent drinking [13]. Group 4: Recommendations for Elevated Tumor Markers - Upon discovering elevated tumor markers, it is advised to consult a specialist at a reputable hospital for further evaluation [14]. - Isolated elevations in tumor markers may not be clinically significant and should be assessed in the context of overall health [14]. - A follow-up examination is recommended after one month if initial results show slight elevations [15]. - Continuous monitoring at the same medical institution is suggested to ensure consistency in results [16]. - Specific characteristics of elevated tumor markers warrant further investigation, including significant single elevations, persistent increases over multiple tests, multiple markers being elevated, or the presence of related symptoms [17].

Company Overview - The company, 极物思维, has submitted a listing application to the Hong Kong Stock Exchange, with CICC and BOCI as joint sponsors [1] - It is positioned as the leading restaurant and bar brand in China, characterized by crafted beverages, selected dishes, and a carefully curated atmosphere for all-day dining and nightlife socializing [1] Market Position - According to Frost & Sullivan, COMMUNE幻师 has ranked first in revenue among Chinese restaurant and bar brands for three consecutive years from 2022 to 2024, with a market share of approximately 7.8% in 2024, which is double that of the second and third largest competitors combined [1] - As of September 30, 2025, the company operates 112 directly managed restaurant and bar locations across 40 cities in China, with 109 of these under the COMMUNE幻师 brand, strategically located in core urban business districts [1] Business Model - The company's business model has a significant focus on alcoholic beverages, with approximately 45% of its revenue coming from drinks, of which about 85% are alcoholic [1] Industry Growth - The Chinese restaurant and bar market is rapidly growing, with a projected market size of 30.1 billion RMB in 2024 and an expected compound annual growth rate (CAGR) of 15.4% from 2025 to 2029; the chain restaurant and bar segment is anticipated to grow even faster, with a CAGR of 22.3% during the same period [1]

Core Insights - The article emphasizes the importance of federal guidelines that prioritize nutrient-dense foods, which include protein, dairy, healthy fats, whole grains, and fruits and vegetables [1] Summary by Categories - **Nutrient-Dense Foods**: Federal guidelines focus on promoting foods that are rich in nutrients, highlighting the significance of including protein, dairy, healthy fats, whole grains, and a variety of fruits and vegetables in diets [1]

Group 1 - The article discusses the misconception surrounding "healthy" food labels, highlighting that a low-sugar, low-fat product can have higher calories than traditional fast food options like McDonald's Big Mac [1][14]. - It emphasizes the trend of categorizing foods into "good" and "bad" based on their perceived health benefits, leading to a culture where individuals feel guilty for consuming "bad" foods [2][3][4]. - The article notes that 74% of surveyed women maintain a personal "food blacklist," indicating a widespread tendency to judge food choices based on health perceptions [3]. Group 2 - The concept of "Orthorexia," or an obsession with healthy eating, is introduced, which can lead to extreme dietary restrictions and social withdrawal [7][20]. - A significant portion of fitness enthusiasts, particularly 52% of gym-goers, are identified as potential candidates for Orthorexia, suggesting a correlation between fitness culture and unhealthy eating habits [8][22]. - The article critiques the "Diet Culture," which links food choices to body image and promotes extreme dieting practices, often at the expense of overall well-being [9][25]. Group 3 - The article advocates for "intuitive eating," which encourages individuals to listen to their body's hunger cues rather than adhering to strict dietary rules [12][35]. - It argues that food should not be morally categorized, and enjoyment of food should be prioritized over calorie counting and guilt [11][44]. - The piece concludes that a balanced approach to eating, which includes social aspects and emotional satisfaction, is essential for a healthy relationship with food [33][32].