随着人们年龄的增长，动脉硬化、心肌纤维化、心力衰竭等相关疾病往往"组团"来袭，危害心血管 健康。近期，中国工程院院士、哈尔滨医科大学药理学教授杨宝峰及其团队连续在国际心血管医学领域 期刊《欧洲心脏杂志》上发表一系列研究成果，这些研究从RNA表观遗传调控和RNA剪接两大前沿微 观领域入手，深刻揭示了血管衰老与心脏纤维化的复杂机制，为疑难心血管疾病的治疗奠定了理论基 础。 锁定血管衰老关键分子 在这些研究中，杨宝峰团队将目标锁定在关键RNA调控分子METTL14上。研究团队借助腺相关病 毒（AAV）载体技术和最新基因敲除技术，特异性降低了老年小鼠血管内皮细胞中METTL14的表达 后，观察到小鼠的血管功能显著改善，血管弹性得以恢复，显现出抗衰老效应。通过进一步研究，团队 发现，在血管衰老过程中，内皮细胞中METTL14的表达升高会使免疫识别受体TLR4 mRNA的特定位置 被修饰，这一修饰可引发持续的慢性低度炎症反应。这种炎症状态最终加快了血管内皮细胞衰老进程， 造成血管硬化和舒张功能异常。 研究团队发现，在心力衰竭的患者及小鼠的心脏中，RBMS1含量明显增多。通过药物抑制或基因 敲除降低RBMS1含量，可有效减 ...

Core Viewpoint - Changchun University of Science and Technology collaborates with Changchun Jingyue High-tech Zone to establish the "Changchun Chip and Optoelectronics Industry Park," aiming to integrate Jilin Province's scientific and educational resources with high-quality innovation resources to promote the innovation resource integration of emerging industries, industrial ecosystem aggregation, technology achievement transformation, innovation and entrepreneurship talent cultivation, and open collaborative development [1] Group 1 - The park has attracted enterprises and project teams in fields such as spectral chips, semiconductor lasers, precision medicine, and optoelectronic medical equipment [1] - The park includes a digital technology enterprise accelerator, a public technology service platform cluster, and specialized incubators in the optoelectronic field [1] - Currently, there are 69 enterprises in the park, including 21 high-tech enterprises, 16 specialized and innovative enterprises, 1 seed unicorn enterprise, 2 fledgling enterprises, and 4 gazelle enterprises [1] Group 2 - The projected operating income of the park's enterprises for 2024 is 527 million yuan [1] - In the future, the Changchun Chip and Optoelectronics Industry Park will continue to strengthen its aggregation effect and enhance communication and cooperation with advanced domestic parks [1] - The goal is to build a high ground for intelligent perception technology and an industrial aggregation area [1]

Core Viewpoint - The new photovoltaic project at Dalian Port's automotive terminal has successfully passed inspection, showcasing significant environmental benefits and energy supply capabilities [1] Group 1: Project Overview - The new photovoltaic project, named "Xinyaobian Photovoltaic Project," has a capacity of 4053 kilowatts and utilizes the rooftop resources of Dalian Automotive Terminal Company [1] - The project was initiated in March and achieved grid connection in June, operating under a "self-consumption and surplus electricity grid connection" model [1] Group 2: Environmental Impact - The project is expected to supply approximately 5.6 million kilowatt-hours of green electricity annually [1] - It will save 1380 tons of standard coal and reduce emissions significantly: 120 kg of smoke dust, 553 kg of sulfur dioxide, 832 kg of nitrogen oxides, and 4536 tons of carbon dioxide each year [1] Group 3: Project Execution - Dalian Automotive Terminal Company coordinated closely with the installation and commissioning of photovoltaic equipment, ensuring safety and efficiency during construction [1]

Core Insights - The Tianzhou-9 cargo spacecraft successfully delivered 23 scientific experiments to the Chinese space station, with significant progress reported in life sciences experiments [1][2] - Three life science experiments involving liver cells, skeletal muscle precursor cells, and brain organoid chips have been completed, demonstrating the potential advantages of nucleic acid drugs in microgravity environments [1][2] Group 1: Life Sciences Experiments - The experiments have successfully achieved automated culture, in-orbit drug administration, microscopic imaging, and sample fixation [1] - In microgravity, the uptake efficiency of nucleic acid drugs by cells significantly increased, leading to a rapid decrease in disease-related protein expression levels, indicating superior therapeutic effects compared to ground control experiments [1][2] Group 2: Skeletal Muscle and Brain Research - Research on the impact of microgravity on skeletal muscle precursor cell migration indicates that migration is hindered, potentially affecting muscle regeneration and homeostasis [2] - The study using organ-on-a-chip technology shows that brain organoids can be cultured in 3D for extended periods in space, with faster neuronal migration observed compared to ground conditions [2] Group 3: Overall Scientific Achievements - As of August 22, 2025, the Chinese space station has implemented 58 scientific and application projects, conducting over 26,000 experiments and transporting more than 800 kilograms of scientific materials [2] - A total of 27 types of space science experiment samples have been returned, yielding 110 terabytes of scientific data [2]

这一新技术将二氧化硅光子学带入了三维世界，为开发高性能集成光学器件开辟了全新可能。 就像大型3D打印机可以制造几乎任何家居用品一样，"光子折纸"技术也能制造各种微型光学器件。例 如，它可以制造微型变焦镜头，从而取代大多数智能手机上配置的5个独立摄像头；也可以制造利用光 而非电的微光子元件，推动传统电子计算机向更快、更高效的光学替代方案转变。 团队在硅芯片上沉积超薄二氧化硅玻璃片，通过刻蚀留出支撑区域，再利用二氧化碳激光脉冲在毫秒级 时间内完成折叠，速度可达每秒2米，加速度超过2000米/秒2。进一步实验表明，该方法可将厚度10微 米的玻璃片折叠成90度直角、螺旋等多种形状，精度可控至0.1微弧度。 团队进一步制作了一种极轻的三维"桌子"结构，并在底部集成凹面腔镜。玻璃片厚度仅5微米左右，像 折纸玩具桌子一样被折叠成型。这类超轻、紧凑的结构原则上可通过光学方式悬浮，用于探索牛顿引力 在极小尺度上的偏差，从而为解决暗物质等天文难题提供新线索。 据最新一期《光学》杂志报道，以色列特拉维夫大学研究人员开发出一种技术，可以直接在芯片上将玻 璃片折叠成微观三维结构，他们称之为"光子折纸"。这一技术有望制造出微小而复杂的光 ...

Group 1 - The core point of the news is the successful implementation of 100% green electricity supply for the venues of the Shanghai Cooperation Organization summit in 2025, marking the first time this has been achieved for such an event [1] - The total green electricity transaction for the summit reached 1 million kilowatt-hours, which is equivalent to reducing 320 tons of standard coal consumption and cutting carbon dioxide emissions by 800 tons [1] - The Tianjin Green Electricity Certificate Service Center facilitated the purchase of 2,250 green certificates for key service locations, translating to an additional 225 million kilowatt-hours of green electricity, further reducing standard coal consumption by 720 tons and carbon dioxide emissions by 1,794 tons [1] Group 2 - In 2023, the market-oriented green electricity trading volume in Tianjin has reached 16.087 billion kilowatt-hours, nearly doubling compared to the previous year [2] - The Tianjin Green Electricity Certificate Service Center has provided full green electricity supply to 214 enterprises, with a total electricity volume of 7.497 billion kilowatt-hours [2] - To ensure reliable electricity supply during the summit, over 4,200 support personnel and more than 1,800 support vehicles will be deployed, along with three emergency repair centers and 101 grid-based power stations on standby [2] Group 3 - The new panoramic power supply command platform will be utilized for real-time monitoring of the entire power supply process from the main grid to the venue's electrical equipment, enhancing efficiency by approximately 65% [2] - Advanced technologies such as intelligent inspection systems, inspection robots, and infrared detection devices will be employed to ensure comprehensive urban power supply security [2]

Core Insights - The successful completion of the first unmanned delivery of electric power materials by the State Grid Corporation marks a significant advancement in logistics efficiency within the energy sector [1] - The unmanned delivery vehicle demonstrated a 30% improvement in delivery efficiency compared to traditional manual methods, achieving a punctuality rate of 98% and a damage rate of 0% for the delivered smart electric meters [1] Group 1 - The unmanned delivery vehicle departed from the State Grid Lianyungang Power Supply Company, carrying 360 smart electric meters to the Zhongyun Power Supply Station [1] - The smart dispatch platform monitored the vehicle's location in real-time, ensuring traceability throughout the delivery process [1] - The delivery was completed in 40 minutes, showcasing the effectiveness of the unmanned system [1] Group 2 - Currently, the State Grid Lianyungang Power Supply Company has deployed 2 unmanned delivery vehicles, covering 6 power supply stations in the main urban area [1] - The unmanned delivery system is capable of operating efficiently even during nighttime, ensuring rapid delivery under special circumstances [1]

Core Viewpoint - Alloy jewelry, known for its "high aesthetic value and low price," has become a new favorite in online consumption, but long-term wear may pose health risks due to potential allergic reactions from certain metal components [1] Group 1: Health Risks Associated with Alloy Jewelry - A case study highlighted a woman in Wuhan who developed contact dermatitis after wearing an alloy necklace continuously, leading to symptoms such as red spots and blisters [1] - Nickel is identified as the primary allergen in alloys, accounting for over 20% of common metal allergies, followed by cobalt and chromium [2] - The allergic reaction mechanism involves a sensitization phase followed by an activation phase, where repeated exposure leads to inflammation and visible symptoms [2] Group 2: Factors Influencing Allergic Reactions - The likelihood of allergic reactions varies with the electrochemical properties of metals and individual immune responses, exacerbated by sweating in hot weather [3] - The release of metal ions from alloys can increase due to sweat, which contains electrolytes that facilitate the electrolysis of metals, leading to potential allergic reactions [3] - While localized contact with jewelry may not cause severe systemic reactions, prolonged exposure can damage the skin barrier and allow metal ions to enter the bloodstream, potentially leading to multi-organ issues [3] Group 3: Recommendations for Safe Use of Alloy Jewelry - Consumers are advised to choose jewelry made from safe materials and to purchase from reputable sources with proper certification [4] - Good wearing habits include removing jewelry during exercise and bathing, and limiting wear time to no more than 8 hours a day, especially in humid conditions [4] - Skin care practices, such as rinsing jewelry after sweating and applying protective creams, are recommended to maintain skin barrier integrity [4]

Core Insights - The Chinese Minmetals Research Team has successfully developed large-scale production technologies for high-end natural graphite materials, addressing the self-sufficiency challenges in China's graphite industry [1][2] - The advancements aim to transition China's graphite industry from a "resource powerhouse" to a "material powerhouse," enhancing the domestic supply of critical materials [1] Group 1: Technological Advancements - The research team has achieved breakthroughs in various technologies, including intelligent mining, "column-machine combined" beneficiation, and high-temperature continuous purification, facilitating the last mile of technology application in the natural graphite industry [1] - The team has developed ultra-pure natural graphite with a purity of 99.99995%, filling a significant gap in the supply of high-end graphite products in China [2] Group 2: Production Capacity - The company has established the world's largest green low-carbon intelligent graphite mine with an annual production capacity of 6 million tons, along with a graphite processing plant capable of producing 280,000 tons annually [2] - The production lines include 100,000 tons of spherical graphite and 80,000 tons of high-purity graphite, showcasing a comprehensive approach to integrating resources, capacity, technology, and new materials [2] Group 3: Future Outlook - The company plans to continue leading industry innovation through technological advancements, focusing on a development strategy of "one generation of raw materials, one generation of equipment, and one generation of products" [2]

Core Insights - The early rice planting area in China for 2025 is 71.143 million acres, a slight decrease of 179,000 acres from the previous year, maintaining overall stability [2] - The early rice yield has increased to 400.8 kg per acre, marking a 1.5% growth from the previous year, with a total production of 57.03 billion pounds, an increase of 6.8 billion pounds or 1.2% [1][2] - The increase in yield is attributed to favorable weather conditions and effective agricultural practices, despite some regional challenges such as drought [1][2] Regional Analysis - Among the 10 major early rice-producing provinces, all except Hainan reported yield increases, with Jiangxi, Hunan, and Guangdong seeing increases of 8.4 kg, 8.0 kg, and 6.3 kg per acre respectively [1] - The planting area in provinces like Zhejiang, Fujian, and Jiangxi has increased, while areas like Anhui and Guangdong experienced slight reductions due to spring drought [2] Government Support - The Chinese government has intensified support for grain production, including raising the minimum purchase price for early indica rice to encourage farmers [2] - The stable planting area for early rice has been maintained at around 71 million acres for six consecutive years, reflecting the effectiveness of government policies [2]