Core Viewpoint - Morgan Stanley has lowered the target price for Fosun Pharma by 4%, from HKD 14.2 to HKD 13.7, while maintaining a "Market Perform" rating [1] Financial Performance - The company’s earnings per share forecasts for 2025-2027 have been reduced by 4-11% due to weak earnings in Q1 2025, primarily impacted by the volume-based procurement (VBP) of generic drugs and a slowdown in new drug growth [1] Capital Expenditure - Morgan Stanley has also revised down its capital expenditure forecasts, indicating no significant acquisitions or new business investments expected [1]

Group 1 - The core viewpoint of the article highlights the decline of the artemisinin concept sector, which fell by 0.82%, ranking among the top declines in the concept sector [1][2] - Within the artemisinin concept sector, major companies such as Rundu Co., Zhejiang Medicine, and Kunming Pharmaceutical experienced significant declines, while only two stocks, Delong Huineng and Baiyunshan, saw increases of 1.06% and 0.37% respectively [1][2] - The article provides a detailed overview of the capital flow, indicating a net outflow of 58 million yuan from the artemisinin concept sector, with Rundu Co. leading the outflow at 43.43 million yuan [2] Group 2 - The article lists the top-performing concept sectors, with the military equipment restructuring concept leading with a gain of 3.92%, while the artemisinin concept was among the worst performers [2] - A table is provided showing the capital flow for various companies within the artemisinin concept, detailing their respective price changes and turnover rates, with Rundu Co. showing a significant outflow [2]

Market Performance - The market rebounded last week, with the China Securities Xinhua National Brand Index rising by 0.94% to 1666.03 points [1] - The Shanghai Composite Index increased by 0.76%, the Shenzhen Component Index by 0.52%, the ChiNext Index by 1.38%, and the CSI 300 Index by 1.12% [1] Strong Stock Performances - Notable strong performers in the brand index included BGI Genomics, which rose by 17.27%, and Yiling Pharmaceutical, which increased by 9.81% [1] - Other significant gainers included Stone Technology and Marubi Biological, which rose by 7.18% and 6.79%, respectively [1] Year-to-Date Stock Gains - Since the beginning of 2025, Marubi Biological has surged by 60.82%, leading the gains, followed by Shanghai Jahwa with a 46.72% increase and BGI Genomics with a 34.45% rise [2] - Other stocks with notable increases include Anji Technology, Xintai, and Weir Shares, each rising over 20% [2] Market Outlook - Institutions expect the market to refocus on domestic economic fundamentals, with a positive policy response anticipated [2][3] - The current market is viewed as being in a high cost-performance range, with significant policy support expected to stabilize the economy and market [2] Economic Data Focus - Attention is drawn to upcoming economic data, particularly export performance and the sustainability of the export supply chain recovery [3] - The prevailing market conditions are supported by policy measures and liquidity easing, which are expected to bolster the stability of the domestic economy and capital markets [3]

Core Viewpoint - SaiLu Medical has completed A+ round financing led by Fosun Pharma, with funds aimed at upgrading domestic sequencing platforms and expanding market presence, driving innovation in life science tools [1][2]. Group 1: Financing and Investment - The A+ round financing was led by Fosun Pharma, with participation from Weichi Investment and existing shareholder Shenzhen Capital Group [2]. - The funds will be primarily used for the registration and declaration of domestic sequencing platforms, capacity expansion, and global market development [2][3]. Group 2: Company Development and Achievements - Since its establishment in 2020, SaiLu Medical has maintained rapid development, achieving significant milestones such as obtaining the NMPA Class III medical device registration for its Salus Pro sequencer in January 2025 [2]. - The company has built a comprehensive R&D system covering optics, fluidics, chips, and reagents, and has accumulated over 100 authorized patents [3]. Group 3: Strategic Collaboration - The financing marks a new phase of strategic cooperation between Fosun Pharma and SaiLu Medical, focusing on product development, resource integration, and global market expansion [6]. - Both companies will emphasize "innovation-driven" strategies to accelerate the development of innovative technologies and products that meet clinical needs [6].

Overview - Shanghai Fosun Pharmaceutical (Group) Co., Ltd. has initiated a Phase I/III clinical trial for HLX13, a biosimilar of ipilimumab, targeting unresectable advanced hepatocellular carcinoma (HCC) patients in China [2]. HLX13 Information and Research Status - HLX13 is a biosimilar of ipilimumab developed by the group, intended for treating multiple cancers including melanoma, renal cell carcinoma, colorectal cancer, HCC, non-small cell lung cancer, malignant pleural mesothelioma, and esophageal squamous cell carcinoma [3]. - As of April 2025, the group has invested approximately RMB 104 million (about $15 million) in the development of HLX13 [3]. - According to IQVIA MIDASTM data, global sales of ipilimumab formulations are projected to reach approximately $2.873 billion in 2024 [3].

Core Viewpoint - The disease prevention and control industry in China is experiencing growth due to increased public awareness, government funding, and advancements in biotechnology and data analysis, leading to improved efficiency in disease management [1][13]. Summary by Sections Industry Overview - Disease prevention and control is a crucial part of public health, focusing on reducing the occurrence and spread of diseases through scientific methods [3]. - Effective disease control can lower healthcare costs, enhance quality of life, and support economic stability [3]. Industry Development - The scale of China's disease prevention and control industry has been on the rise, with central government funding for disease control projects increasing from 17.526 billion to 20.38 billion from 2020 to 2022, followed by a projected recovery to 20.881 billion in 2024, marking an 18.06% year-on-year increase [1][13]. - The number of disease control centers in China has grown from 3,376 in 2021 to 3,429 in 2024, enhancing public health emergency management capabilities [11]. Policy Initiatives - Recent policies emphasize strengthening disease control institutions, enhancing core functions, and promoting scientific research and public health cooperation [5][7]. - The 2024-2025 National Disease Prevention and Control Action Plan encourages local institutions to engage in applied research and technology transfer [5][7]. Competitive Landscape - The disease prevention market in China is competitive, with key players including Fosun Pharma, Kangtai Biological, and Zhifei Biological, which are focusing on innovation and service quality to capture market share [15][19]. Industry Trends - The chronic disease management market is expected to grow significantly due to the aging population and increasing prevalence of chronic diseases, which currently account for 88% of total deaths in China [21]. - Technological innovations such as big data, AI, and IoT are set to transform disease prevention and control, enhancing monitoring and decision-making processes [22]. - The integration of sports and health ("body-health integration") is emerging as a new trend, promoting physical activity as a preventive measure against chronic diseases [23].

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性或完整性亦不 發表任何聲明，並明確表示，概不對因本公告全部或任何部份內容而產生或因倚賴該等內容而引致的任何損 失承擔任何責任。 陳玉卿 上 海 復 星 醫 藥（ 集 團 ）股 份 有 限 公 司 Shanghai Fosun Pharmaceutical (Group) Co., Ltd.* （於中華人民共和國註冊成立的股份有限公司） （股份代號：02196） 海外監管公告 本公告乃根據香港聯合交易所有限公司證券上市規則第13.10B條而作出。 茲載列上海復星醫藥（集團）股份有限公司（「本公司」）在上海證券交易所網站刊登的《關於 控股子公司藥品臨床試驗進展的公告》，僅供參閱。 承董事會命 上海復星醫藥（集團）股份有限公司 董事長 中國，上海 2025 年5 月1 6 日 於本公告日期，本公司之執行董事為陳玉卿先生、關曉暉女士、文德鏞先生及王可心先生；本公司之非執行 董事為陳啟宇先生、徐曉亮先生、潘東輝先生及吳以芳先生；以及本公司之獨立非執行董事為李玲女士、湯 谷良先生、王全弟先生及余梓山先生。 * 僅供識別 证券代码：60019 ...

证券代码：600196 股票简称：复星医药 编号：临 2025-089 截至 2025 年 4 月，本集团现阶段针对 HLX13 累计研发投入约为人民币 1.04 亿 元（未经审计）。 根据 IQVIA MIDAS TM最新数据 1，2024 年，伊匹木单抗制剂于全球范围内的销售 额约为 28.73 亿美元。 上海复星医药（集团）股份有限公司 关于控股子公司药品临床试验进展的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 一、概况 近日，上海复星医药（集团）股份有限公司（以下简称"本公司"）控股子公 司上海复宏汉霖生物技术股份有限公司及其控股子公司自主研发的伊匹木单抗生物 类似药 HLX13（重组抗 CTLA-4 全人单克隆抗体注射液，以下简称"HLX13"）一线 治疗不可切除的晚期肝细胞癌（HCC）患者于中国境内启动 I/III 期临床试验。 二、HLX13 的基本信息及研究情况 HLX13 为本集团（即本公司及控股子公司/单位，下同）自主研发的伊匹木单抗 生物类似药，拟用于治疗黑色素瘤、肾细胞癌、结直肠癌、肝细胞癌、 ...

Investment Rating - The investment rating for the company is "Buy" (maintained) [6] Core Views - The company is expected to continue its growth driven by sustained high investment in R&D and ongoing internationalization and innovation efforts [1][5] - The company reported a rapid profit growth and improved cash flow, with a 2024 revenue of 41.067 billion yuan, a slight decrease of 0.80% year-over-year [1] - The core innovative products, including the PD-1 monoclonal antibody and CAR-T cell therapy, have shown steady revenue growth [1][2] Summary by Sections Financial Performance - In 2024, the company achieved a net profit of 2.770 billion yuan, an increase of 16.08% year-over-year, with a non-GAAP net profit of 2.314 billion yuan, up 15.10% [2] - The gross margin improved, and the selling expense ratio increased by 2.45 percentage points year-over-year, while management expenses decreased by 355 million yuan [2] Business Segmentation - The pharmaceutical segment generated 28.924 billion yuan in revenue, with a segment profit of 3.250 billion yuan, reflecting a year-over-year growth of 65.73% [3] - The medical devices and diagnostics segment reported a revenue of 4.323 billion yuan, a decrease of 1.53% due to declining COVID-related product sales [3] - The healthcare services segment achieved a revenue of 7.647 billion yuan, an increase of 14.61%, although it still reported a loss of 315 million yuan [4] Future Outlook - The company plans to maintain high R&D investment, with a total of 5.554 billion yuan allocated in 2024, representing 16.98% of the pharmaceutical business revenue [5] - The company is advancing its internationalization strategy, with several products receiving approvals in the US and Europe [6][11] - The earnings per share (EPS) forecast for 2025-2027 is projected at 1.22, 1.37, and 1.57 yuan, respectively, with a price-to-earnings (P/E) ratio of 20 times based on the closing price on May 13, 2025 [12]

Investment Rating - The investment rating for the company is "Buy" (maintained) [6] Core Views - The company is expected to continue its growth driven by ongoing innovation and internationalization efforts [1][5] - The company reported a rapid profit growth and improved cash flow for 2024, with operating revenue reaching 41.067 billion yuan, a year-over-year decrease of 0.80% [1] - The company achieved a net profit of 2.770 billion yuan in 2024, an increase of 16.08% year-over-year, with a non-GAAP net profit of 2.314 billion yuan, up 15.10% [2] Summary by Sections Performance Overview - The company’s revenue for 2024 was 41.067 billion yuan, with innovative products contributing to steady growth [1] - Operating cash flow improved to 4.477 billion yuan, a year-over-year increase of 31.13% [1] Business Segmentation - The pharmaceutical segment generated revenue of 28.924 billion yuan in 2024, with a segment profit of 3.250 billion yuan, reflecting a year-over-year growth of 65.73% [3] - The medical devices and diagnostics segment reported revenue of 4.323 billion yuan, a decrease of 1.53% year-over-year, primarily due to declining COVID-related product sales [3] - The healthcare services segment achieved revenue of 7.647 billion yuan, a year-over-year increase of 14.61%, although it still reported a segment loss of 315 million yuan [4] Future Outlook - The company plans to maintain high R&D investment, with total R&D expenditure reaching 5.554 billion yuan in 2024, representing 16.98% of pharmaceutical revenue [5] - The company is advancing its internationalization strategy, with several products receiving approvals in international markets, including the US and Europe [6] - Earnings per share (EPS) forecasts for 2025-2027 are projected at 1.22, 1.37, and 1.57 yuan, respectively [12]