证券代码：600557 证券简称：康缘药业 公告编号：2025-037 江苏康缘药业股份有限公司 关于公司实际控制人、董事增持公司股份的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 江苏康缘药业股份有限公司（以下简称"公司"）实际控制人、董事肖伟 先生基于对公司未来发展的信心以及对公司长期投资价值的认可，近日通过上海 证券交易所交易系统以集中竞价的方式，以自有资金增持公司股份 20,000 股， 占公司总股本的 0.0035%，累计增持金额 325,200 元（不含交易费用）。本次增 持不触及权益变动报告义务。 本次增持未导致公司控股股东及实际控制人发生变化。 | | 江苏康缘集团有 | | | 公司实际控制人肖 | | --- | --- | --- | --- | --- | | | 限责任公司（简 | 176,173,467 | 31.1173 | 伟先生之控股公司， | | | 称"康缘集团"） | | | 公司的控股股东 | | | 上海银叶投资有 限公司－银叶攻 玉 10 号私募证 券投资基金（简 称"银叶 ...

南 京 市 建 邺 区 贤 坤 路 江 岛 智 立 方 C 座 4 层 F 4 , Bu i l d i n g C, Ji a n g d a o I n t e l l i g e n t Cu b e , X i a n k u n Ro a d , Ji a n y e D istr i c t , N a n j i n g 电 话 / Te l ： + 8 6 2 5 - 8 3 3 0 4 4 8 0 传 真 / F a x ： + 8 6 2 5 - 8 3 3 2 9 3 3 5 邮 编 / P. C.： 2 1 0 0 1 9 江苏世纪同仁律师事务所 关于江苏康缘药业股份有限公司 实际控制人增持公司股份的 法 律 意 见 书 江 苏 世 纪 同 仁 律 师 事 务 所 关 于 江 苏 康 缘 药 业 股 份 有 限 公 司 实 际 控 制 人 增 持 公 司 股 份 的 法 律 意 见 书 苏 同 律 证 字 （ 2025） 第 [294]号 1 3、为出具本法律意见书，本所事先对本次增持事项进行了尽职调查，并获 得相关方如下声明和保证：相关方已向本所提供了出具本法律意见书所必需且力 所能 ...

Core Viewpoint - The actual controller and director of Kangyuan Pharmaceutical, Xiao Wei, increased his shareholding through a centralized bidding method on the Shanghai Stock Exchange, indicating confidence in the company's future prospects [1] Group 1: Shareholding Details - Xiao Wei purchased 20,000 shares for a total amount of 325,200 yuan, which represents 0.0035% of the company's total share capital [1] - Prior to the purchase, Xiao Wei held 17,003,200 shares, accounting for 3.0033% of the total shares [1] - After the increase, Xiao Wei and his concerted parties collectively hold 208 million shares, which is 36.6859% of the total shares [1] Group 2: Regulatory Compliance - The share increase does not trigger the obligation to report changes in equity and does not lead to a change in the controlling shareholder or actual controller [1] - Jiangsu Century Tongren Law Firm provided a special verification opinion confirming compliance with regulations [1]

人民财讯11月18日电，康缘药业（600557）11月18日公告，公司实际控制人、董事肖伟近日通过上海证 券交易所交易系统以集中竞价的方式，以自有资金增持公司股份2万股，占公司总股本的0.0035%，累 计增持金额32.52万元(不含交易费用)。 ...

Core Viewpoint - The demand for antiviral and cough-relief medications is rising due to the seasonal increase in respiratory infections among children, with Kangyuan Pharmaceutical's Jin Zhen Oral Liquid emerging as a leading product in this market, driving the company's steady growth [1][5]. Financial Performance - In 2024, Kangyuan Pharmaceutical achieved a total revenue of 3.898 billion yuan, with Jin Zhen Oral Liquid contributing approximately 815 million yuan, accounting for over 20% of total revenue, and a year-on-year sales volume increase of 5.13% to 21.39 million units [1][5]. - For the first three quarters of 2025, the company reported total revenue of 2.343 billion yuan, with oral liquid products, led by Jin Zhen Oral Liquid, generating 1.359 billion yuan, representing a 58% share and becoming the core growth driver for the respiratory medication segment [1][5]. - The company's net profit attributable to shareholders reached 200 million yuan in the first three quarters, with a net operating cash flow of 346 million yuan, maintaining robust profitability during industry adjustments [2]. Product Efficacy and Market Position - Jin Zhen Oral Liquid demonstrates a comprehensive efficacy profile with antiviral, anti-inflammatory, and symptom-relieving properties, making it a preferred choice for treating respiratory infections in children [1][4]. - The product has shown a total effective rate of 97% in treating acute respiratory infections, and it significantly reduces recovery times for hand-foot-mouth disease and acute bronchitis compared to conventional treatments [4][5]. - The formulation is based on traditional Chinese medicine principles and has been clinically validated for its effectiveness in treating various respiratory conditions in children [3][4]. Competitive Advantage - Jin Zhen Oral Liquid has established a unique competitive edge through its differentiated positioning as a child-specific medication with optimized taste, achieving a 98% acceptance rate among children [6]. - The company has maintained a strong focus on research and development, with R&D expenditures consistently above 10% of sales revenue over the past three years, reaching 15.02% in the first three quarters of 2025 [6]. - The product has been included in national health insurance and essential drug lists, enhancing its market presence across multiple provinces [7].

Core Insights - Lianyungang is enhancing its business environment through innovative services and supportive government policies, aiming to create a more favorable atmosphere for enterprises [1][9] Group 1: Logistics and Trade - Lianyungang is actively innovating in logistics to reduce costs and improve efficiency, with 772 international freight trains operated from January to October this year [2] - The city has established six premium freight train routes covering Central Asia and Europe, significantly expanding its service reach [2] - A new data corridor between Lianyungang and Horgos is being developed to enhance connectivity and efficiency in the New Eurasian Land-Sea Corridor, reducing cargo handling time from 30 hours to under 5 hours, achieving an overall efficiency increase of 80% [3] Group 2: Regulatory Reforms - The city has implemented a "comprehensive inspection once" reform, reducing redundant inspections by 12,710 times this year, a decrease of 46.59%, thus alleviating the burden on enterprises [6] - Lianyungang has streamlined environmental approval processes, allowing a company to complete necessary permits in just 15 days, significantly faster than previous timelines [4] Group 3: Pharmaceutical Industry - The "Chinese Medicine Port" in Lianyungang is fostering a robust pharmaceutical ecosystem, attracting companies like Shenzhen Beimei Pharmaceutical, which established a children's medicine production base [7] - The economic development zone has developed a "4+N" industrial system, with the new pharmaceutical industry being a key pillar, housing major companies and becoming a significant base for innovative drugs and exports [7][8] Group 4: Government Initiatives - The local government is focused on continuous improvement of the business environment, with a dedicated leadership group and regular meetings to address optimization efforts [10] - Lianyungang is enhancing administrative efficiency through standardized processes and a unified service platform, aiming to improve the overall experience for businesses [11][12]

Core Viewpoint - Kangyuan Pharmaceutical's stock has experienced fluctuations, with a current price of 16.06 CNY per share and a market capitalization of 9.093 billion CNY, reflecting a year-to-date increase of 17.91% [1] Group 1: Stock Performance - As of November 17, Kangyuan Pharmaceutical's stock price decreased by 2.01% during the trading session [1] - The stock has seen a 1.90% increase over the last five trading days and a 3.81% increase over the last twenty days, while it has declined by 9.01% over the last sixty days [1] Group 2: Financial Performance - For the period from January to September 2025, Kangyuan Pharmaceutical reported a revenue of 2.343 billion CNY, a year-on-year decrease of 24.66% [2] - The net profit attributable to shareholders for the same period was 200 million CNY, reflecting a year-on-year decrease of 44.10% [2] Group 3: Shareholder Information - As of September 30, 2025, the number of shareholders for Kangyuan Pharmaceutical increased by 17.20% to 40,500 [2] - The average number of circulating shares per shareholder decreased by 14.68% to 13,969 shares [2] - The company has distributed a total of 949.8 million CNY in dividends since its A-share listing, with 345 million CNY distributed over the last three years [3]

Core Insights - The avian influenza concept sector saw an increase of 1.21%, ranking 10th among concept sectors, with 16 stocks rising, including Zhongsheng Pharmaceutical which hit the daily limit, and Hualan Vaccine, Kangyuan Pharmaceutical, and Yiling Pharmaceutical showing notable gains of 7.22%, 4.53%, and 3.14% respectively [1][2] Group 1: Stock Performance - Zhongsheng Pharmaceutical led the sector with a net inflow of 7.32 billion yuan, while Kangyuan Pharmaceutical, Yiling Pharmaceutical, and Hualan Vaccine also experienced significant net inflows of 3274.76 million yuan, 3130.43 million yuan, and 2904.55 million yuan respectively [2][3] - The top gainers in the avian influenza concept included Zhongsheng Pharmaceutical with a daily increase of 9.98%, followed by Hualan Vaccine at 7.22%, and Kangyuan Pharmaceutical at 4.53% [3][4] Group 2: Market Trends - The avian influenza concept sector attracted a net inflow of 6.66 billion yuan today, with 10 stocks receiving net inflows, and 6 stocks exceeding 10 million yuan in net inflow [2] - The net inflow ratios for leading stocks were 36.05% for Zhongsheng Pharmaceutical, 8.22% for Dongfang Bio, and 7.21% for Rhine Bio, indicating strong investor interest in these companies [3][4]

Core Insights - The traditional Chinese medicine sector experienced a slight increase of 0.52% on November 14, with Jia Ying Pharmaceutical leading the gains [1] - The Shanghai Composite Index closed at 3990.49, down 0.97%, while the Shenzhen Component Index closed at 13216.03, down 1.93% [1] Stock Performance - Jia Ying Pharmaceutical (002198) closed at 7.66, up 10.06% with a trading volume of 275,500 shares and a transaction value of 203 million yuan [1] - Zhongsheng Pharmaceutical (002317) closed at 26.00, up 9.98% with a trading volume of 791,200 shares and a transaction value of 2.03 billion yuan [1] - Te Yi Pharmaceutical (002728) closed at 15.21, up 9.98% with a trading volume of 1,662,000 shares and a transaction value of 2.44 billion yuan [1] - Other notable performers include Fangsheng Pharmaceutical (603998) with a 4.92% increase and Kangyuan Pharmaceutical (600557) with a 4.53% increase [1] Capital Flow - The traditional Chinese medicine sector saw a net inflow of 541 million yuan from institutional investors, while retail investors experienced a net outflow of 17.84 million yuan [2] - Major stocks like Zhongsheng Pharmaceutical and Te Yi Pharmaceutical had significant net inflows from institutional investors, indicating strong interest [3] - Conversely, retail investors showed a tendency to withdraw from several stocks, including Jia Ying Pharmaceutical and Kangyuan Pharmaceutical, reflecting a cautious sentiment [3]

Core Points - The Shanghai Composite Index is at 4017.68 points, above the six-month moving average, with a slight decline of 0.29% [1] - A total trading volume of A-shares reached 15648.48 billion yuan today [1] - 113 A-shares have surpassed the six-month moving average, with notable stocks showing significant deviation rates [1] Summary by Category Stock Performance - The top three stocks with the highest deviation rates from the six-month moving average are: - Electric Investment and Financing (9.07%) - Jie Rong Technology (7.54%) - Annie Shares (4.91%) [1] - Other stocks with smaller deviation rates that have just crossed the six-month line include: - Baoland, Zhongnong Lihua, and Subote [1] Trading Data - The trading performance of selected stocks includes: - Electric Investment and Financing: +9.94% with a turnover rate of 2.09% - Jie Rong Technology: +10.00% with a turnover rate of 8.20% - Annie Shares: +6.44% with a turnover rate of 18.47% [1] - Additional stocks with notable performance include: - Yahua Electronics: +6.29% - Zhonglu Shares: +7.08% - Jinlihua Electric: +4.81% [1]