Core Viewpoint - The financing activities of Huada Zhizao indicate a moderate interest from investors, with net buying observed over recent trading days [1] Financing Summary - On August 19, Huada Zhizao had a financing buy amount of 0.36 billion, ranking 754th in the market, with a financing repayment amount of 0.27 billion, resulting in a net buy of 9.61 million [1] - Over the last three trading days (August 15-19), Huada Zhizao received financing buys of 0.39 billion, 0.47 billion, and 0.36 billion respectively [1] Securities Lending Summary - On August 19, the company had a securities lending sell of 0.13 thousand shares, with a net buy of 2.20 thousand shares [1]

Summary of BGI Genomics Conference Call Company Overview - BGI Genomics is a leading company in the field of gene sequencing, benefiting from import substitution and technological innovation, with stable growth in core business and an increase in the proportion of reagent consumables to 60%, which helps improve overall gross margin [2][5][7] Core Business Insights - The company has reduced production costs and improved gross margins through self-production of raw materials and optimization of AI algorithms, while actively digesting excess inventory from the pandemic period to improve financial conditions [2][7] - The cost of gene sequencing continues to decline, with diminishing marginal effects from hardware optimization, leading to a greater reliance on AI technology for efficiency improvement, cost reduction, and quality control [2][10] Technological Advancements - BGI's second-generation sequencing technology uses rolling circle amplification, avoiding error accumulation from PCR, thus improving testing accuracy, particularly excelling in long-read sequencing with single-end 600BP sequencing reagents achieving Q40 [2][12][14] Market Position and Competition - Following sanctions on Illumina by the Chinese Ministry of Commerce, BGI is expected to dominate the incremental market, although there remains significant replacement potential in the existing market, with a market share of approximately 40% [2][20] - The company has achieved stable growth in the domestic market due to ongoing import substitution, while overseas market growth has faced challenges due to geopolitical factors, although these issues have recently been alleviated [6][34] Financial Performance - The core gene sequencing business maintains a stable gross margin of around 60%, with further improvement potential. The company has gradually promoted self-production of raw materials and developed proprietary AI protein design algorithms to enhance selection efficiency [7][34] - Despite high expenses due to inventory and accounts receivable impairments during the pandemic, the reduction in accounts receivable has improved quality, leading to lower impairment pressure [7] Industry Outlook - The gene sequencing industry has significant growth potential, being fundamental to biomedicine, with applications in agriculture, industry, research, and health [8] - The decline in sequencing costs is driven by the speed of Moore's Law and the large-scale commercialization of second-generation sequencing technology, particularly by Illumina [10] Applications and Future Trends - The downstream applications of gene sequencing are expanding, particularly in tumor early screening, companion diagnostics, and minimal residual disease (MRD) monitoring, with the LDT model playing a crucial role in domestic tumor gene sequencing [27][28] - AI technology is enhancing the efficiency of gene sequencing interpretation, facilitating the expansion of clinical applications and improving the capabilities of healthcare providers [24][29] Challenges and Opportunities - The market faces challenges such as low coverage rates in secondary and primary hospitals for newborn screening and difficulties in obtaining certification for tumor gene sequencing [25] - However, the introduction of AI technology presents new opportunities for hospitals, and the restrictions on accessing U.S. databases are prompting domestic efforts to strengthen gene data infrastructure [26][29] Conclusion - BGI Genomics is well-positioned in the gene sequencing market, with a strong focus on technological innovation and market expansion, particularly in the context of changing geopolitical dynamics and the growing importance of AI in healthcare applications [2][34]

华大智造保荐人(主承销商)为中信证券股份有限公司，保荐代表人为肖少春、路明，联席主承销商为中 国国际金融股份有限公司、瑞银证券有限责任公司。发行费用总额为31,767.74万元，其中，承销保荐费 27,154.28万元。 中国经济网北京8月19日讯华大智造(688114.SH)今日收报69.60元，跌幅2.15%。 华大智造募集资金总额为360,223.18万元，扣除发行费用后，募集资金净额为328,455.44万元。公司最终 募集资金净额较原计划多75670.91万元。华大智造于2022年9月6日发布的招股说明书显示，公司计划募 集资金252,784.53万元，分别用于华大智造智能制造及研发基地项目、基于半导体技术的基因测序仪及 配套设备试剂研发生产项目、华大智造研发中心项目、华大智造营销服务中心建设项目、华大智造信息 化系统建设项目、补充流动资金。 华大智造于2022年9月9日在上海证券交易所科创板上市，发行数量为4,131.9475万股，发行价格87.18 元/股，目前该股处于破发状态。 ...

华大智造于2022年9月9日在上海证券交易所科创板上市，发行数量为4,131.9475万股，发行价格87.18 元/股，目前该股处于破发状态。 中国经济网北京8月14日讯华大智造(688114.SH)今日收报67.81元，跌幅3.43%。 华大智造保荐人(主承销商)为中信证券股份有限公司，保荐代表人为肖少春、路明，联席主承销商为中 国国际金融股份有限公司、瑞银证券有限责任公司。发行费用总额为31,767.74万元，其中，承销保荐费 27,154.28万元。 华大智造募集资金总额为360,223.18万元，扣除发行费用后，募集资金净额为328,455.44万元。公司最终 募集资金净额较原计划多75670.91万元。华大智造于2022年9月6日发布的招股说明书显示，公司计划募 集资金252,784.53万元，分别用于华大智造智能制造及研发基地项目、基于半导体技术的基因测序仪及 配套设备试剂研发生产项目、华大智造研发中心项目、华大智造营销服务中心建设项目、华大智造信息 化系统建设项目、补充流动资金。 ...

人民财讯8月13日电，8月12日，追光生物科技(深圳)有限公司(简称"追光生物")与华大智造宣布达成战 略合作关系。此次合作双方将共同打造覆盖"筛选—测序—数据分析"全流程的自主可控的抗体发现平 台，加速生命科学仪器的产业化进程。 ...

证券之星消息，8月12日精准医疗板块较上一交易日上涨0.09%，复星医药领涨。当日上证指数报收于 3665.92，上涨0.5%。深证成指报收于11351.63，上涨0.53%。精准医疗板块个股涨跌见下表： 从资金流向上来看，当日精准医疗板块主力资金净流出6.94亿元，游资资金净流入1.13亿元，散户资金净 流入5.82亿元。精准医疗板块个股资金流向见下表： | 代码 | 名称 | 主力净流入(元) | 主力净占比 游资净流入 (元) | | 游资净占比 散户净流入 (元) | | 散户净占比 | | --- | --- | --- | --- | --- | --- | --- | --- | | 002093 | 国脉科技 | 3921.58万 | 4.60% | 1196.77万 | 1.40% | -5118.35万 | -6.00% | | 688271 | 联影医疗 | 3222.21万 | 4.34% | -904.30万 | -1.22% | -2317.91万 | -3.12% | | 300030 阳普医疗 | | 1932.05万 | 5.42% | -864.75万 | -2.43% | ...

Group 1: Company Insights - The report highlights BGI Genomics (华大智造) as a leading domestic gene sequencer, with significant progress in both domestic and international markets, driven by its DNBSEQ technology [9][10] - The global gene sequencer and reagent market is projected to grow at a compound annual growth rate (CAGR) of 16.8%, reaching USD 20.2 billion by 2032, indicating a robust expansion opportunity for the company [9] - The company is expected to see revenue growth from CNY 36.06 billion in 2025 to CNY 49.32 billion in 2027, with a net profit forecasted to increase from CNY 0.07 billion to CNY 2.94 billion during the same period [11] Group 2: Industry Trends - The gene sequencing technology is rapidly expanding into various downstream applications, including clinical medicine, research, and personal consumption, enhancing the overall industry landscape [9] - The AI education sector is witnessing a surge, with companies like Duolingo reporting better-than-expected earnings, suggesting a positive trend for domestic AI education products [19] - The renewable energy sector, particularly in solar and wind, is experiencing price recovery due to policy support and market dynamics, with significant opportunities for companies involved in these industries [21][22] Group 3: Market Performance - The consumer services sector in the A-share market saw a 4.59% increase in July, driven by AI-related stocks and quality consumption trends [16] - The AIDC (Artificial Intelligence Data Center) power equipment sector is benefiting from increased capital expenditures by major internet companies, indicating a strong demand for related technologies [25] - The solid-state battery industry is progressing with various companies announcing advancements in production and application, reflecting a growing market for innovative battery technologies [31]

Group 1 - The report from Guosen Securities on August 8 gives BGI Genomics (688114.SH, latest price: 69.29 CNY) an outperform rating due to the continuous expansion of downstream application scenarios and the rapid growth of the gene sequencing instrument market [2] - BGI Genomics is positioned as the industry leader in domestic gene sequencing instruments, leveraging its core DNBSEQ technology to build a comprehensive product pipeline [2] - The company is solidifying its leadership in the sequencing instrument business through innovation upgrades, while AI empowerment is opening new chapters in automated business [2]

Investment Rating - The investment rating for the company is "Outperform the Market" (maintained) [2] Core Views - The company is a leading domestic gene sequencer, with accelerated progress in both domestic and international markets. The dual drivers of domestic and overseas business are expected to enhance the company's market share [3][4] - The gene sequencing market is rapidly expanding, with a projected compound annual growth rate (CAGR) of 16.8% for the global gene sequencer and reagent market, expected to reach USD 20.2 billion by 2032 [4][48] - The company leverages its core DNBSEQ technology to build a comprehensive product pipeline, meeting diverse needs in research and clinical applications, with high accuracy and lower costs compared to global leader Illumina [4][5] Company Overview - The company has established itself as a domestic leader in gene sequencing instruments, continuously innovating and upgrading its product offerings, including the upcoming StandardMPS 2.0 sequencing reagent, which aims to lead the industry into the Q40 era of sequencing quality [4][18] - The company has a well-structured product matrix covering low, medium, and high throughput sequencing, with a focus on automation and AI integration to enhance operational efficiency and sequencing precision [4][21] Financial Performance and Forecast - The company is expected to achieve revenues of CNY 36.06 billion, CNY 42.81 billion, and CNY 49.32 billion for the years 2025, 2026, and 2027, respectively, with year-on-year growth rates of 19.7%, 18.7%, and 15.2% [5][6] - The projected net profit for the company is expected to turn positive by 2025, with estimates of CNY 0.07 billion, CNY 1.50 billion, and CNY 2.94 billion for the years 2025, 2026, and 2027, respectively [5][6] Industry Overview - The gene sequencing industry is experiencing rapid growth, driven by the expansion of downstream applications in clinical, research, and personal health management sectors. The global gene sequencing market is projected to grow from USD 15.54 billion in 2023 to USD 62.48 billion by 2030, with a CAGR of 22.2% [48][49] - The domestic gene sequencing market is expected to reach CNY 374 billion by 2024, with a projected CAGR of 26.5% from 2024 to 2030, supported by national policies and funding [62][63]

本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重大遗漏，并对其内容 的真实性、准确性和完整性承担法律责任。 重要内容提示： 深圳华大智造科技股份有限公司（以下简称"公司"）董事会于近日收到公司董事朱岩梅女士的《辞任报 告》，朱岩梅女士因个人原因申请辞去公司董事职务。根据《中华人民共和国公司法》（以下简称《公 司法》）、《公司章程》及有关法律法规的规定，朱岩梅女士的辞任申请自《辞任报告》送达公司董事 会时生效，朱岩梅女士辞任未导致公司董事会成员人数低于法定人数，不会影响公司董事会的正常运 行，其职务变动不会对公司正常经营活动产生不利影响。 公司于2025年8月6日召开2025年第一次职工代表大会，选举谢伟伟女士为公司第二届董事会职工代表董 事，谢伟伟女士与公司第二届董事会现任5名非独立董事、4名独立董事共同组成公司第二届董事会。具 体情况如下： 一、董事提前辞任的基本情况 ■ 二、董事辞任对公司的影响 朱岩梅女士辞任未导致公司董事会成员人数低于法定人数，不会影响公司董事会的正常运行，其职务变 动不会对公司正常经营活动产生不利影响。 朱岩梅女士在担任公司董事期间恪尽职守、勤勉尽责，为公司持 ...