关于深圳华大智造科技股份有限公司 2024 年员工持股计划修订相关事项的 法律意见书 深圳华大智造科技股份有限公司： 北京市君合（深圳）律师事务所（以下简称"本所"）接受深圳华大智造科 技股份有限公司（以下简称"公司"）的委托，就公司 2024 年员工持股计划（以 下简称"本次计划"）修订相关事项（以下简称"本次修订"）之事宜，根据《中 华人民共和国公司法》（以下简称"《公司法》"）、《中华人民共和国证券法》（以 下简称"《证券法》"）、《关于上市公司实施员工持股计划试点的指导意见》（以下 简称"《试点指导意见》"）、《上海证券交易所科创板上市公司自律监管指引第 1 号——规范运作》（以下简称"《规范运作指引》"）等中华人民共和国（以下简称 "中国"，仅为出具本法律意见书之目的，"中国"不包括中国香港特别行政区、 中国澳门特别行政区和中国台湾省）正式公布并实施的有关法律、法规、规范性 文件和《深圳华大智造科技股份有限公司章程》（以下简称"《公司章程》"）的有 关规定，出具本法律意见书。 为出具本法律意见书，本所律师对公司提供的与出具本法律意见书有关的文 件资料进行了审查，并取得公司向本所作出的如下保证：公司已 ...

证券简称：华大智造 证券代码：688114 上海荣正企业咨询服务（集团）股份有限公司 关于 深圳华大智造科技股份有限公司 2024 年限制性股票激励计划、2024 年员工持股 计划修订相关事项 之 独立财务顾问报告 $$\mathbf{\partial}\mathbf{\partial}\mathbf{\partial}\mathbf{\partial}=\mathbf{\partial}\mathbf{\partial}\mathbf{\partial}$$ 2 | | | 上海荣正企业咨询服务（集团）股份有限公司 独立财务顾问报告 一、释义 | 华大智造、本公司、 | 指 | 深圳华大智造科技股份有限公司 | | --- | --- | --- | | 公司、上市公司 | | | | 本激励计划、激励计 | 指 | 深圳华大智造科技股份有限公司 2024 年限制性股票 | | 划 | | 激励计划 | | 持股计划、本持股计 | 指 | 深圳华大智造科技股份有限公司 2024 年员工持股计 | | 划 | 划 | | | 限制性股票、第二类 | 指 | 符合本激励计划授予条件的激励对象，在满足相应 | | ...

Core Insights - Huada Zhizao reported a significant reduction in net loss by 65.28% year-on-year for the first half of 2025, with main business revenue reaching 1.091 billion yuan [1] - The company achieved a historical high in instrument sales, with over 700 units sold, marking a 60.35% increase year-on-year [1] - Operational efficiency improved, with a 37.55% reduction in net loss after deducting non-recurring items [1] Business Performance - Main business revenue for the first half of 2025 was 1.091 billion yuan, with a notable reduction in net loss [1] - The company’s operating expenses (excluding financial costs) decreased by 17.04% to 827 million yuan [1] - The core long-read sequencing business remains a key growth driver for the company [1] Supply Chain and Production - The company collaborated with over 50 suppliers to enhance core material efficiency, achieving a 25% improvement in overall supply chain efficiency [1] - Global spare parts delivery rate improved to 90%, with the China region reaching 91.04% [1] - The company maintains a leading position in the industry with a 72-hour delivery cycle [1] Technological Advancements - Huada Zhizao is advancing its laboratory automation business through AI technology, restructuring its operations to enhance efficiency [2] - The company developed an AI closed-loop solution covering the entire "Design-Build-Test-Learn" process, significantly reducing R&D cycles [2] - The integration of AI tools supports a transition from manual decision-making to data-driven processes in laboratories [2]

深圳华大智造科技股份有限公司2025 年半年度报告 公司代码：688114 公司简称：华大智造 深圳华大智造科技股份有限公司 2025 年半年度报告 1 / 279 深圳华大智造科技股份有限公司2025 年半年度报告 重要提示 一、 本公司董事会、监事会及董事、监事、高级管理人员保证半年度报告内容的真实性、准确 性、完整性，不存在虚假记载、误导性陈述或重大遗漏，并承担个别和连带的法律责任。 二、 重大风险提示 公司已在本报告中详细阐述公司在经营过程中可能面临的各种风险，有关内容敬请查阅本报告第 三节"管理层讨论与分析"之"四、风险因素"。 三、 公司全体董事出席董事会会议。 四、 本半年度报告未经审计。 五、 公司负责人牟峰、主管会计工作负责人刘波及会计机构负责人（会计主管人员）胡浩声明： 保证半年度报告中财务报告的真实、准确、完整。 六、 董事会决议通过的本报告期利润分配预案或公积金转增股本预案 不适用 七、 是否存在公司治理特殊安排等重要事项 □适用 √不适用 八、 前瞻性陈述的风险声明 √适用 □不适用 本报告中所涉及的未来计划、发展战略等前瞻性描述不构成公司对投资者的实质承诺，敬请投资 者注意投资风险 ...

（一）依法合规原则 深圳华大智造科技股份有限公司 2024 年员工持股计划管理办法（修订稿） 第一章 总则 第一条 为规范深圳华大智造科技股份有限公司（以下简称"华大智造"或"公司"） 2024 年员工持股计划（以下简称"本持股计划"或"本计划"或"持股计划"）的实 施，根据《中华人民共和国公司法》（以下简称"《公司法》"）《中华人民共和国 证券法》以下简称"《证券法》"、中国证监会《关于上市公司实施员工持股计划试 点的指导意见》（以下简称"《指导意见》"）、《上海证券交易所科创板上市公司 自律监管指引第 1 号——规范运作》（以下简称"《自律监管指引第 1 号》"）等 相关法律、行政法规、规章、规范性文件和《公司章程》《深圳华大智造科技股份 有限公司 2024 年员工持股计划（草案修订稿）》之规定，特制定《深圳华大智造 科技股份有限公司 2024 年员工持股计划管理办法（修订稿）》（以下简称"本办法" 或"《持股计划管理办法》"）。 第二章 持股计划的制定 第二条 持股计划的基本原则 公司实施持股计划，严格按照法律、行政法规的规定履行程序，真实、准确、 完整、及时地实施信息披露。任何人不得利用持股计划进行内 ...

2024 年限制性股票激励计划实施考核管理办法（修订稿） 深圳华大智造科技股份有限公司（以下简称"公司"）为进一步完善公司法 人治理结构，健全公司的长效激励约束机制，吸引留住优秀人才，充分调动公司 员工的积极性，有效将股东利益、公司利益和员工利益三者紧密结合，共同促进 公司的长远发展，确保公司发展战略和经营目标的实现，公司拟实施 2024 年限 制性股票激励计划（以下简称"股权激励计划"或"限制性股票激励计划"）。 为保证股权激励计划的顺利实施，现根据《中华人民共和国公司法》《中华 人民共和国证券法》《上市公司股权激励管理办法》《上海证券交易所科创板股票 上市规则》《科创板上市公司自律监管指南第 4 号——股权激励信息披露》等有 关法律、法规和规范性文件以及《深圳华大智造科技股份有限公司章程》、公司 《2024 年限制性股票激励计划（草案修订稿）》的相关规定，并结合公司的实际 情况，特制定 2024 年限制性股票激励计划实施考核管理办法（修订稿）（以下简 称"本办法"）。 深圳华大智造科技股份有限公司 一、考核目的 进一步完善公司法人治理结构，建立和完善公司激励约束机制，保证公司 2024 年限制性股票激励计 ...

| 688114 | 华大智 | 6.61 | 3.90 | 73.77 | 74.63 | 1.16 | | --- | --- | --- | --- | --- | --- | --- | | | 造 | | | | | | | 600126 | 杭钢股 | 5.10 | 10.99 | 10.19 | 10.30 | 1.07 | | | 份 | | | | | | | 002003 | 伟星股 | 1.06 | 0.95 | 11.33 | 11.45 | 1.04 | | | 份 | | | | | | | 002607 | 中公教 | 4.01 | 9.18 | 3.08 | 3.1 1 | 1.04 | | | 育 | | | | | | | 603110 | 东方材 料 | 3.66 | 12.49 | 16.54 | 16.69 | 0.92 | | 605117 | 德业股 | 3.43 | 2.77 | 57.99 | 58.51 | 0.89 | | | 份 | | | | | | | 002541 | 鸿路钢 | 3.02 | 3.78 | 18.31 | 18.44 | 0.70 ...

Group 1 - The Shanghai Composite Index is at 3783.05 points, above the five-day moving average, with a change of 0.32% [1] - The total trading volume of A-shares today is 1,080.3 billion yuan [1] - A total of 276 A-shares have prices that have surpassed the five-day moving average, with notable stocks including San Chuan Wisdom, Ping Gao Co., and Tong Hui Electronics, showing divergence rates of 13.32%, 13.23%, and 9.93% respectively [1] Group 2 - The top three stocks with the highest divergence rates from the five-day moving average are: - San Chuan Wisdom (300066) with a price increase of 20.06% and a divergence rate of 13.32% [2] - Ping Gao Co. (688227) with a price increase of 19.99% and a divergence rate of 13.23% [2] - Tong Hui Electronics (833509) with a price increase of 16.85% and a divergence rate of 9.93% [2] - Other notable stocks include Ding Tai Gao Ke (301377) with a divergence rate of 8.41% and An Fu Technology (603031) with a divergence rate of 7.32% [2]

Core Viewpoint - The financing activities of Huada Zhizao indicate a moderate interest from investors, with net buying observed over recent trading days [1] Financing Summary - On August 19, Huada Zhizao had a financing buy amount of 0.36 billion, ranking 754th in the market, with a financing repayment amount of 0.27 billion, resulting in a net buy of 9.61 million [1] - Over the last three trading days (August 15-19), Huada Zhizao received financing buys of 0.39 billion, 0.47 billion, and 0.36 billion respectively [1] Securities Lending Summary - On August 19, the company had a securities lending sell of 0.13 thousand shares, with a net buy of 2.20 thousand shares [1]

Summary of BGI Genomics Conference Call Company Overview - BGI Genomics is a leading company in the field of gene sequencing, benefiting from import substitution and technological innovation, with stable growth in core business and an increase in the proportion of reagent consumables to 60%, which helps improve overall gross margin [2][5][7] Core Business Insights - The company has reduced production costs and improved gross margins through self-production of raw materials and optimization of AI algorithms, while actively digesting excess inventory from the pandemic period to improve financial conditions [2][7] - The cost of gene sequencing continues to decline, with diminishing marginal effects from hardware optimization, leading to a greater reliance on AI technology for efficiency improvement, cost reduction, and quality control [2][10] Technological Advancements - BGI's second-generation sequencing technology uses rolling circle amplification, avoiding error accumulation from PCR, thus improving testing accuracy, particularly excelling in long-read sequencing with single-end 600BP sequencing reagents achieving Q40 [2][12][14] Market Position and Competition - Following sanctions on Illumina by the Chinese Ministry of Commerce, BGI is expected to dominate the incremental market, although there remains significant replacement potential in the existing market, with a market share of approximately 40% [2][20] - The company has achieved stable growth in the domestic market due to ongoing import substitution, while overseas market growth has faced challenges due to geopolitical factors, although these issues have recently been alleviated [6][34] Financial Performance - The core gene sequencing business maintains a stable gross margin of around 60%, with further improvement potential. The company has gradually promoted self-production of raw materials and developed proprietary AI protein design algorithms to enhance selection efficiency [7][34] - Despite high expenses due to inventory and accounts receivable impairments during the pandemic, the reduction in accounts receivable has improved quality, leading to lower impairment pressure [7] Industry Outlook - The gene sequencing industry has significant growth potential, being fundamental to biomedicine, with applications in agriculture, industry, research, and health [8] - The decline in sequencing costs is driven by the speed of Moore's Law and the large-scale commercialization of second-generation sequencing technology, particularly by Illumina [10] Applications and Future Trends - The downstream applications of gene sequencing are expanding, particularly in tumor early screening, companion diagnostics, and minimal residual disease (MRD) monitoring, with the LDT model playing a crucial role in domestic tumor gene sequencing [27][28] - AI technology is enhancing the efficiency of gene sequencing interpretation, facilitating the expansion of clinical applications and improving the capabilities of healthcare providers [24][29] Challenges and Opportunities - The market faces challenges such as low coverage rates in secondary and primary hospitals for newborn screening and difficulties in obtaining certification for tumor gene sequencing [25] - However, the introduction of AI technology presents new opportunities for hospitals, and the restrictions on accessing U.S. databases are prompting domestic efforts to strengthen gene data infrastructure [26][29] Conclusion - BGI Genomics is well-positioned in the gene sequencing market, with a strong focus on technological innovation and market expansion, particularly in the context of changing geopolitical dynamics and the growing importance of AI in healthcare applications [2][34]