Policy Developments - The National Medical Products Administration (NMPA) has announced the implementation of the "Quality Management Standards for Online Sales of Medical Devices," effective from October 1, 2025. Regulatory authorities are required to guide online sellers and e-commerce platforms in conducting internal training and assessments related to quality management systems, product information display, and risk monitoring [2]. Drug and Device Approvals - BeiGene announced positive results from the Phase 2 clinical trial (DeLLphi-307) of tarlatamab for treating extensive-stage small cell lung cancer (ES-SCLC) patients in China, with detailed data to be presented at an upcoming medical conference [4]. Capital Market Activities - Shanghai BoYin Biotechnology Co., Ltd. has completed a multi-million angel round financing, led by Zhangjiang Life and Health Industry Incubation Angel Fund, with funds aimed at advancing the company's product pipeline and early clinical validation of its first product [7]. Industry Developments - Yuheng Pharmaceutical has signed a co-promotion agreement with Xinghe Pharmaceutical for Pemafibrate, a novel selective PPARα modulator, which will take effect on June 1, 2025. This agreement is expected to enhance Yuheng's product pipeline and potential profit growth, although it will face competition from established products [9]. Shareholder Activities - Chengdu XianDao announced that shareholder Anji Dongfang Jiayu Enterprise Management Partnership reduced its stake by 1 million shares, decreasing its ownership from 6.2% to 5.95% [12]. - BioVeda China RMB Investment Limited plans to reduce its stake in AoJing Medical by up to 135,550 shares, having already reduced its holdings by 34,510 shares, representing 0.25% of the total shares [13].

证券代码：688222 证券简称：成都先导 公告编号：2025-021 成都先导药物开发股份有限公司关于持股 5%以上 股东安吉东方佳钰企业管理合伙企业（有限合伙） 权益变动触及 1%刻度的提示性公告 投资者安吉东方佳钰企业管理合伙企业(有限合伙)保证向本公司提供的信息真实、 准确、完整，没有虚假记载、误导性陈述或重大遗漏。 本公司董事会及全体董事保证公告内容与信息披露义务人提供的信息一致。 一、 信息披露义务人及其一致行动人的基本信息 1.身份类别 | | □控股股东/实际控制人及其一致行动人 | | --- | --- | | | ☑其他 5%以上大股东及其一致行动人 | | 投资者及其一致行动人的身份 | □合并口径第一大股东及其一致行动人（仅适用 | | | 于无控股股东、实际控制人） | | | □其他______________（请注明） | 2.信息披露义务人信息 | 信息披露义务人名称 | 投资者身份 | 统一社会信用代码 | | --- | --- | --- | | □ 安吉东方佳钰企业管 □ | 控股股东/实控人 控股股东/实控人的一致 | ☑91540091321366628A | | ...

证券代码：688222 证券简称：成都先导 公告编号：2025-020 成都先导药物开发股份有限公司 关于董事会、监事会延期换届及公司独立董事任期 公司董事会、监事会延期换届不会影响公司的正常运营。公司将积极推进相 关工作，尽快完成董事会、监事会的换届选举工作并及时履行信息披露义务。 二、公司独立董事任期届满提出辞职 公司独立董事余海宗先生连任公司独立董事已满 6 年，根据《公司法》《公 司章程》等有关规定，因任期届满，余海宗先生向公司董事会提出了辞职申请， 并申请辞去审计委员会主任委员、提名委员会委员、薪酬与考核委员会委员职务。 余海宗先生离任将导致公司独立董事人数少于董事会成员三分之一，在选举出的 新任独立董事就任前，余海宗先生将依照法律、行政法规、部门规章和《公司章 程》规定，继续履行相应职责。 截至本公告披露日，余海宗先生未持有公司股份。余海宗先生在担任公司独 1 届满提出辞职的提示性公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 一、 公司董事会、监事会延期换届的情况 成都先导药物开发股份有限公司（以下简称 ...

证券代码：688222 证券简称：成都先导 公告编号：2025-019 成都先导药物开发股份有限公司 2024年年度股东大会决议公告 本公司董事会及全体董事保证公告内容不存在任何虚假记载、误导性陈述或 者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 重要内容提示： 本次会议是否有被否决议案：无 一、 会议召开和出席情况 （一） 股东大会召开的时间：2025 年 05 月 23 日 （二） 股东大会召开的地点：成都市双流区慧谷东一路 8 号天府国际生物城 C2 栋成都先导药物开发股份有限公司二楼大会议室 （三） 出席会议的普通股股东、特别表决权股东、恢复表决权的优先股股东及 其持有表决权数量的情况： | 1、出席会议的股东和代理人人数 | 125 | | --- | --- | | 普通股股东人数 | 125 | | 2、出席会议的股东所持有的表决权数量 | 180,442,852 | | 普通股股东所持有表决权数量 | 180,442,852 | | 3、出席会议的股东所持有表决权数量占公司表决权数量的比 | 45.1738 | | 例（%） | | | 普通股股东所持有表决权数量占公司表决 ...

成都高新区交子大道 233 号 中海国际中心 C 座 28 层 邮编：610041 电话：（86-28）6739-8000 传真：（86-28）6739-8001 junhecd@junhe.com 北京君合（成都）律师事务所 关于成都先导药物开发股份有限公司 2024 年年度股东大会的法律意见书 致：成都先导药物开发股份有限公司 北京君合（成都）律师事务所（以下简称"本所"）受成都先导药物开发 股份有限公司（以下简称"贵公司"）的委托，根据《中华人民共和国公司法》 （以下简称《公司法》）等中国现行有效的有关法律、行政法规、部门规章、 规范性文件（以下合称"法律法规"，仅为本法律意见书法律适用之目的，不 包括中国香港特别行政区、中国澳门特别行政区及台湾地区的法律法规）及 《成都先导药物开发股份有限公司章程》（以下简称《公司章程》）的有关规 定，就贵公司 2024 年年度股东大会（以下简称"本次股东大会"）有关事宜出 具本法律意见书。 本法律意见书仅就本次股东大会的召集和召开程序是否符合法律、行政法 规和《公司章程》的规定，以及出席本次股东大会人员的资格、本次股东大会 召集人资格、本次股东大会的表决程序和表决结 ...

Group 1: Stock Performance - Yibin Paper (600793.SH) has experienced a significant short-term stock price increase and a substantial rise in trading volume [1] - Sanofi Health (688336.SH) has seen a cumulative stock price increase of over 100% since May 19, 2025, indicating potential irrational speculation and a possible correction [1] - Laisun Tongling (603900.SH) has shown a notable short-term increase in stock price and turnover rate, exceeding most companies in the industry [1] Group 2: Project Investments - Youyan Powder Materials (688456.SH) plans to establish a subsidiary to invest in an additive manufacturing metal powder materials industrial base [1] - Suqian Agricultural Development (601952.SH) intends to initiate a project for the construction of a 14,000-ton grain storage facility [1] Group 3: Contract Awards - Zhongnan Media (601098.SH) has signed a procurement contract through its wholly-owned subsidiary [1] Group 4: Operating Data - China Power Construction (601669.SH) reported a total new contract amount of 386.49 billion yuan from January to April, a year-on-year decrease of 4.9% [1] - China Chemical (601117.SH) recorded a total contract amount of 123.017 billion yuan from January to April [1] Group 5: Equity Acquisitions - Health元 (600380.SH) announced that its controlling subsidiary, Lizhu Group, plans to acquire equity in Vietnam's IMP company [1] Group 6: Share Buybacks - Geling Deep Vision (688207.SH) has completed a buyback of 1.29% of its shares [1] Group 7: Shareholding Changes - Yiwan Yichuang (300792.SZ) shareholders Zhang Fan and director Lu Hualiang plan to reduce their holdings by up to 3.02% [1] - Daqian Ecology (603955.SH) has announced that Xinhua Publishing Group intends to reduce its holdings by up to 3% [1] - Hongli Zhihui (300219.SZ) controlling shareholder plans to increase holdings by 25 million to 50 million yuan [1] - Sanfeng Environment (601827.SH) controlling shareholder intends to increase holdings by 150 million to 300 million yuan [1] - Chengdu Xian Dao (688222.SH) plans to increase holdings by 25 million to 50 million yuan [1] Group 8: Strategic Partnerships - Tiantie Technology (300587.SZ) has signed a strategic cooperation framework agreement with Xinjie Energy [2]

登录新浪财经APP 搜索【信披】查看更多考评等级 证券代码：688222 证券简称：成都先导 公告编号：2025-018 重要内容提示： ● 本次增持主体宁波聚智先导生物科技合伙企业（有限合伙）（以下简称"聚智先导"）为成都先导药物 开发股份有限公司（以下简称"公司"或"成都先导"）持股5%以上股东、员工持股平台，与公司控股股 东、实际控制人JIN LI（李进）为一致行动人关系。截至本公告披露日，聚智先导持有公司38,651,163 股股份，占总股本的比例为9.65%，JIN LI（李进）持有公司81,876,948股股份，占总股本的比例为 20.43%，聚智先导与JIN LI（李进）合计持有公司120,528,111股股份，占总股本的比例为30.08%。 ● 成都先导于今日收到公司控股股东、实际控制人JIN LI（李进）的一致行动人聚智先导的通知，基于 对公司未来持续稳定发展的信心以及对公司股票长期投资价值的认可，聚智先导拟自本公告披露之日起 12个月内，通过包括但不限于集中竞价、大宗交易等上海证券交易所交易系统允许的方式增持公司股 份，合计增持金额不低于人民币2,500万元（含）且不高于人民币5,000万 ...

随着增持专项贷加速落地，上市公司近期频频披露增持消息。 5月22日晚间成都先导（688222）公告，当日收到公司控股股东、实际控制人JIN LI（李进）的一致行 动人宁波聚智先导生物科技合伙企业（有限合伙）（下称"聚智先导"）通知，基于对公司未来持续稳定 发展的信心以及对公司股票长期投资价值的认可，聚智先导拟自公告披露之日起12个月内，通过包括但 不限于集中竞价、大宗交易等上海证券交易所交易系统允许的方式增持公司股份，合计增持金额不低于 2500万元（含）且不高于5000万元（含）。 聚智先导为成都先导员工持股平台。截至公告披露日，聚智先导持有上市公司3865.12万股股份，占总 股本的比例为9.65%。 成都先导表示，本次增持计划不设置增持股票价格区间，资金来源为其自有资金及兴业银行股份有限公 司成都分行提供的专项贷款。 当晚鸿利智汇（300219）也披露，控股股东四川金舵投资有限责任公司（下称"四川金舵"）计划自公告 披露之日起6个月内，通过深交所系统以集中竞价方式或大宗交易方式增持公司股份，拟增持金额合计 不低于2500万元且不超过5000万元。 公告显示，本次增持前，四川金舵持有上市公司股份占总股本的 ...

Group 1 - Hongchuang Holdings plans to acquire 100% equity of Shandong Hongtuo Industrial for 63.518 billion yuan, transforming from a single aluminum deep processing business to a full industry chain including electrolytic aluminum, alumina, and aluminum deep processing [3] - LIZHU Group intends to acquire 64.81% of Vietnam's Imexpharm Corporation for approximately 1.587 billion yuan, enhancing its presence in the pharmaceutical sector [4][5] - China Power Construction reported a new contract amount of 386.49 billion yuan from January to April, a year-on-year decrease of 4.9% [7] Group 2 - Wanhua Chemical announced a scheduled maintenance for its production facilities, including a five-month technical upgrade for its Yantai ethylene unit, which will not significantly impact operations [8] - Changhong High-Tech received a warning letter from the Ningbo Securities Regulatory Bureau for failing to disclose related party transactions in a timely manner [9] - Highgreat plans to invest 10 million yuan in Blue Core Computing, which focuses on RISC-V architecture chips [10] Group 3 - Xidi Micro plans to increase capital by 30 million USD in its wholly-owned subsidiary Hong Kong Xidi Micro to support its expanding business [12] - Bichuang Technology lost its high-tech enterprise qualification, resulting in an increase in corporate income tax rate from 15% to 25% for the years 2023 to 2025 [13] - Tonghua Dongbao intends to transfer 5.7% of its shares in Xiamen Tebao Biological Engineering for a total of 1.301 billion yuan [16] Group 4 - Tian Tie Technology signed a strategic cooperation agreement with Shenzhen Xinjie Energy to collaborate on solid-state battery lithium metal anode materials [23] - Nanjing Port disclosed that its stock trading has shown signs of market sentiment overheating, indicating potential irrational trading behavior [24] - Zhongnan Media signed a government procurement contract worth 1.009 billion yuan, ensuring stable revenue for its main business [25]

Group 1 - Yong'an Pharmaceutical announced that its stock price has seen a significant short-term increase, indicating a risk of market sentiment overheating, although there are no major changes in the company's fundamentals [3] - China Power Construction reported that from January to April 2025, the company signed new contracts worth 386.49 billion yuan, a decrease of 4.9% year-on-year [4] - Wanhua Chemical announced a scheduled maintenance for its production facilities, including a technical upgrade for its ethylene unit, which is expected to last approximately five months, while ensuring that other units continue to operate normally [5] Group 2 - Changhong High-Tech received a warning letter from the Ningbo Securities Regulatory Bureau for failing to timely disclose related party transactions exceeding expected amounts, with the company secretary held responsible [6] - Gaweida plans to invest 10 million yuan in Blue Core Computing, acquiring a 0.6729% stake in the company, which focuses on RISC-V architecture chip solutions [7] Group 3 - Zhongnan Media signed a government procurement contract worth 1.009 billion yuan, ensuring stable revenue from educational materials for the 2025 fiscal year [9] - Hongli Zhihui's controlling shareholder plans to increase their stake in the company by investing between 25 million and 50 million yuan [11] - Xingye Co.'s controlling shareholder intends to reduce their stake by up to 1% of the total share capital due to personal asset allocation needs [12] - Chengdu Xian Dao's employee stockholding platform plans to invest between 25 million and 50 million yuan to increase its stake in the company, with no set price range for the purchase [13]