东海证券指出，我国创新药具备研发成本低、效率高的优点，或成为BD交易首选，中国有望成为低成本研发与生产中心，加速从"仿制跟随"向"创新主 导"转型。大型跨国药企在更严格的定价体系下可能积极寻求降低研发生产成本的路径，我国CXO产业链或将进一步巩固市场地位。仿制药方面，美国仿制 药市场因价格压缩可能引发生产商退出，导致供应短缺，我国具备ANDA批件积累的仿制药企业有望抢占市场份额。建议关注创新药链、器械设备、中药、 医疗服务、连锁药店等细分板块及个股的投资机会。 科创综指ETF华夏紧密跟踪上证科创板综合指数，上证科创板综合指数由上海证券交易所符合条件的科创板上市公司证券组成指数样本，并将样本分红计入 指数收益，反映上海证券交易所科创板上市公司证券在计入分红收益后的整体表现。 科创综指ETF华夏(589000)，场外联接(华夏上证科创板综合ETF联接A：023719；华夏上证科创板综合ETF联接C：023720)。 以上内容与数据，与有连云立场无关，不构成投资建议。据此操作，风险自担。 截至2025年5月20日 14:24，上证科创板综合指数(000680)上涨0.57%，成分股三生国健(688336)上涨19. ...

Group 1 - The Hang Seng Biotechnology Index will include companies Same Origin Health (02410.HK) and Kangji Medical (09997.HK) [1] - The index will exclude companies CStone Pharmaceuticals-B (09966.HK) and Rongchang Biopharmaceuticals (09995.HK) [1]

Group 1 - The innovative pharmaceutical ETF (560900) has seen a 0.89% increase, marking a four-day rising streak, with the index tracking the innovative drug industry (931152) up by 0.85% [1] - Notable stock performances include Maiwei Biotech (688062) rising over 9%, Tianshili (600535) up 4.76%, and Baotai (688177) increasing by 4.38% [1] - The innovative pharmaceutical ETF has experienced a significant growth of 4 million shares in the last three months, indicating a recovery in market enthusiasm for the pharmaceutical sector [2] Group 2 - The pharmaceutical and biotechnology sector's Q1 2025 financial reports show stable revenue and profit performance, with notable improvements in certain sub-industries [2] - The market sentiment towards the pharmaceutical sector has shifted positively, ending a continuous downtrend since Q1 2024, driven by a systematic valuation increase in the innovative drug sector [2] - Long-term potential exists in China's biomanufacturing, quantum technology, embodied intelligence, and 6G industries, with significant development opportunities across the entire industrial chain [2] Group 3 - Morgan Asset Management is integrating its "Global Vision Investment Technology" product line to assist investors in seizing investment opportunities in quality technology companies globally [2] - Various actively managed funds focus on emerging industry trends, including the Morgan Emerging Power Fund and the Morgan Smart Connectivity Fund, which targets artificial intelligence opportunities [3] - The Morgan Hang Seng Technology ETF and the Morgan Zhongzheng Innovative Pharmaceutical Industry ETF provide passive investment options for technology and innovative pharmaceutical sectors [3]

Group 1 - The stock market showed strength on May 14, with both the ChiNext Index and Shanghai Composite Index rising over 1%, while the Hong Kong Hang Seng Index increased by 2% and the Hang Seng Tech Index rose by over 2% [1] - Popular ETFs such as the Biopharmaceutical ETF (159859) and the Innovative Drug Hong Kong-Shanghai ETF (517380) turned positive in the afternoon, with the Innovative Drug ETF up 0.35% and key components like China National Pharmaceutical Group and Hengrui Medicine rising over 3% [1] - The Biopharmaceutical ETF tracks the National Biopharmaceutical Index, which includes the top 30 stocks in the biopharmaceutical sector based on market capitalization and liquidity, reflecting the overall performance of the industry [1] Group 2 - The 36th Pharmaceutical Economic Information Conference was held in Guangzhou from May 12 to 14, focusing on drug regulation policies, industry trends, and high-quality development in the pharmaceutical sector [2] - According to Founder Securities, the pharmaceutical and biotechnology sector's Q1 2025 financial reports showed stable revenue and profit performance, with notable improvements in certain sub-sectors, particularly in pharmaceutical R&D outsourcing, which achieved over 10% growth in both revenue and profit [2] - The market sentiment towards the pharmaceutical industry has improved, with a noticeable increase in equity fund allocations since Q1 2024, driven by a systematic valuation increase in the innovative drug sector [2]

Group 1 - The Hong Kong stock market opened with the Hang Seng Index rising by 0.9% and the Hang Seng Tech Index increasing by 1.58%, indicating a positive market sentiment towards innovative pharmaceuticals [1] - The Hong Kong Innovative Drug ETF (159567) showed active trading with a turnover exceeding 85 million yuan and a trading volume increase of 0.51%, reflecting strong investor interest [1] - Major stocks in the innovative drug sector, such as Rongchang Biopharmaceutical and China Biologic Products, saw significant gains, with increases of over 3% and 2% respectively [1] Group 2 - Huayuan Securities reported that innovative drug companies are projected to achieve revenues of 47.53 billion yuan in 2024, marking a year-on-year growth of 68.4%, indicating a robust growth trend [2] - Domestic innovative drug companies have largely completed their R&D cycles, with core products entering a phase of rapid commercialization, leading to accelerated revenue growth [2] - The trend of overseas licensing has emerged as a second growth curve for biotech companies, providing sustainable funding support for ongoing R&D through high upfront payments [2]

为进一步加强与投资者的互动交流，荣昌生物制药（烟台）股份有限公司（以下 简称"公司"）将参加由山东证监局、山东上市公司协会与深圳市全景网络有限公司 联合举办的"2025 年山东辖区上市公司投资者网上集体接待日活动"，现将相关事 项公告如下： 证券代码：688331 证券简称：荣昌生物 公告编号：2025-023 港股代码：09995 港股简称：榮昌生物 本次活动将采用网络远程的方式举行，投资者可登录"全景路演"网站 （http://rs.p5w.net）；或关注微信公众号（名称：全景财经）；或下载全景路演 APP, 参与本次互动交流。活动时间为 2025 年 5 月 15 日（周四）15:00-16:30。届时公司 高管将在线就公司 2024 年度业绩、公司治理、发展战略、经营状况、融资计划、股 权激励和可持续发展等投资者关心的问题，与投资者进行沟通与交流，欢迎广大投资 者踊跃参与！ 荣昌生物制药（烟台）股份有限公司 关于参加 2025 年山东辖区上市公司投资者 网上集体接待日活动的公告 特此公告。 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚 假记载、误导性陈述或重大遗漏。 荣昌生物制药 ...

Group 1 - The core viewpoint is that the pharmaceutical sector is focusing on innovation, with a positive trend in innovative drugs supported by policies and increasing global competitiveness [2] - The Shanghai Stock Exchange Science and Technology Innovation Board Biomedicine Index has shown a 1.27% increase, indicating a recovery in the biotech sector [1] - The ETF tracking the Biomedicine Index has seen a 1.17% rise, with significant trading volume exceeding 8.12 million yuan, reflecting investor interest [1] Group 2 - The pharmaceutical industry is expected to see a recovery in demand by 2025, particularly in the consumer healthcare sector, driven by improving economic fundamentals [2] - The medical device sector is also anticipated to improve by 2025, indicating a broader recovery in the healthcare industry [2] - AI in healthcare is highlighted as a significant technological trend that could bring changes to the pharmaceutical industry [2] Group 3 - The pharmaceutical index has stabilized after a period of decline since 2021, with signs of recovery beginning in Q4 2024 [2] - The ongoing innovation in the pharmaceutical sector, along with favorable drug procurement policies, is expected to drive a new growth cycle [2] - The aging population and unmet clinical needs are contributing to long-term growth trends in the pharmaceutical industry [2]

Company Announcements - Zhaowei Electromechanical plans to reduce its shareholding by no more than 1.5%, equating to approximately 3.6 million shares [1] - China CNR Corporation has signed several major contracts totaling approximately 54.74 billion yuan, representing about 22.2% of its expected revenue for 2024 [2] - Yunnan Copper is planning to acquire a 40% stake in Liangshan Mining, leading to a temporary suspension of its stock [2] - Sunshine Nuohua intends to acquire 100% of Langyan Life, with its stock set to resume trading [3] - Wolong Materials is planning to issue H-shares and apply for a listing on the Hong Kong Stock Exchange [3] - Hanyu Pharmaceutical has signed a joint development agreement for a novel peptide drug targeting metabolic diseases [3] - Lijun Co. confirms that its operations are normal and there are no undisclosed significant matters [3] Investments & Acquisitions - China Medical plans to acquire 100% of Jinsui Technology for 302 million yuan [4] - Shuangyi Technology intends to acquire 100% of Marky Industries for 18 million AUD, along with specific assets [5] Strategic Partnerships - Sileck has signed a strategic cooperation agreement with Lihua Power for the development of large cylindrical batteries [6] - Hongchang Technology plans to invest 15 million yuan in a humanoid robot industry chain company [7] - Macroview Technology is establishing a wholly-owned subsidiary focused on artificial intelligence [8] - Yihua Jiaye has signed a strategic cooperation framework agreement with Hanyu Pharmaceutical and Hanyu Health to develop a sleep health ecosystem [9] - Wanda Film is investing in Lezi Tiancheng and will engage in strategic cooperation in IP toy product development [10] Shareholding Changes - Tiandi Online's controlling shareholder is transferring 6.97% of its shares to introduce a strategic investor [12] - Longjiang Transportation plans to reduce its shareholding by no more than 3% [13] - Boyun New Materials intends to reduce its shareholding by no more than 3% [14] - Tongrun Equipment's major shareholder plans to reduce its stake by no more than 2% [15] Financing & Capital Increase - Tangyuan Electric plans to raise no more than 864 million yuan through a private placement [16] - Shangsheng Electronics intends to issue convertible bonds to raise up to 330 million yuan [17] Other Developments - Xianju Pharmaceutical has obtained a domestic production registration certificate for Dydrogesterone tablets [18] - Rongchang Bio has received a clinical trial application acceptance notice for its antibody-drug conjugate RC278 [19] - Jiangsu Leili's subsidiary Dingzhi Technology is implementing a stock incentive plan [20]

一、 基本情况介绍 | | | 荣昌生物制药（烟台）股份有限公司 自愿披露关于维迪西妥单抗一线治疗 HER2 表达的尿路上 皮癌Ⅲ期临床研究达到主要研究终点的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重 大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 荣昌生物制药（烟台）有限公司（以下简称"公司"或"荣昌生物"）自主研发的 抗体偶联药物（ADC）维迪西妥单抗（代号：RC48，商品名：爱地希®）联合特瑞普利单 抗对比化疗治疗 HER2 表达的一线局部晚期或转移性尿路上皮癌的Ⅲ期临床研究 （RC48-C016）达到无进展生存期（PFS）和总生存期（OS）两项主要研究终点。现将情 况公告如下： RC48-C016 研究是一项随机对照、多中心Ⅲ期临床研究，于 2022 年 6 月启动，全 国 74 家临床研究中心参与，共入组 484 例受试者，在既往未接受过系统治疗且存在 HER2 表达（HER2 IHC 1+、2+或 3+）的局部晚期或转移性尿路上皮癌患者中，对比维迪西妥 单抗联合特瑞普利单抗和吉西他滨联合顺铂/卡铂的疗效和安全性。 二、 临床进展情况 维迪西妥单抗联合特 ...

| 证券代码：688331 | 证券简称：荣昌生物 | 公告编号：2025-021 | | --- | --- | --- | | 港股代码：09995 | 港股简称：榮昌生物 | | 荣昌生物制药（烟台）股份有限公司 自愿披露关于抗体偶联药物 RC278 获得药物临床试验申请 受理通知书的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重 大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 一、 药品基本情况 由于医药产品具有高科技、高风险、高附加值的特点，药品的前期研发以及产品从 研制、临床试验报批到投产的周期长、环节多，容易受到一些不确定性因素的影响。敬 请广大投资者谨慎决策，注意防范投资风险。 审批结论：根据《中华人民共和国行政许可法》第三十二条的规定，经审查，决定 予以受理。 二、 药品的其他相关情况 RC278 是由荣昌生物自主研发的一款具有 First-in-Class/Best-in-Class 潜质的 ADC 分子，该分子能特异识别一个新型肿瘤靶点，并具有创新的连接子—毒素系统，在 临床前研究中展现出广谱抗肿瘤活性、良好的安全性和药代动力学特征，将为晚期实体 ...