Market Overview - The biopharmaceutical sector increased by 0.36% compared to the previous trading day, with Jindike leading the gains [1] - The Shanghai Composite Index closed at 3864.18, down 0.15%, while the Shenzhen Component Index closed at 12907.83, up 1.02% [1] Stock Performance - Jindike (688670) saw a closing price of 30.90, with a significant increase of 20.00% and a trading volume of 192,400 shares, amounting to a transaction value of 572 million [1] - Rongchang Bio (688331) closed at 92.25, up 5.43%, with a trading volume of 68,800 shares and a transaction value of 635 million [1] - Sanofi (688336) closed at 68.39, up 4.59%, with a trading volume of 74,400 shares and a transaction value of 510 million [1] - Other notable performers include Olin Bio (616889) with a 4.43% increase and Hualan Bio (301207) with a 3.21% increase [1] Fund Flow Analysis - The biopharmaceutical sector experienced a net inflow of 20.94 million from institutional investors, while retail investors saw a net outflow of 57.02 million [2] - Jindike had a net inflow of 57.00 million from institutional investors, despite a net outflow of 19.76 million from retail investors [3] - Rongchang Bio also saw a net inflow of 32.94 million from institutional investors, with retail investors withdrawing 25.48 million [3]

Group 1 - The Hong Kong pharmaceutical and biotechnology sector showed strong performance on November 26, with notable gains in several companies [1] - Rongchang Biopharmaceutical, CSPC Pharmaceutical Group, and 3SBio each saw their stock prices increase by over 6% [1] - Other companies such as Fuhong Hanlin, Cornerstone Pharmaceuticals, and China National Pharmaceutical Group also experienced significant price increases [1]

Market Overview - The biopharmaceutical sector increased by 0.83% on November 25, with Jindike leading the gains [1] - The Shanghai Composite Index closed at 3870.02, up 0.87%, while the Shenzhen Component Index closed at 12777.31, up 1.53% [1] Top Gainers in Biopharmaceutical Sector - Jinke (688670) closed at 25.75, up 19.99% with a trading volume of 92,200 shares [1] - Hualan Biological (301207) closed at 23.33, up 11.25% with a trading volume of 250,500 shares [1] - Saiseng Pharmaceutical (300485) closed at 11.95, up 5.19% with a trading volume of 168,000 shares [1] - Other notable gainers include Bohui Innovation (300318) at 6.84 (+3.32%) and Dongbao Biological (300239) at 5.72 (+3.25%) [1] Market Capital Flow - The biopharmaceutical sector saw a net inflow of 40.88 million yuan from institutional investors, while retail investors experienced a net outflow of 147 million yuan [2] - The sector's overall capital flow indicates a strong interest from institutional investors despite retail selling pressure [2] Individual Stock Capital Flow - Jinke (688670) had a net inflow of 39.66 million yuan from institutional investors, while retail investors showed a net outflow of 13.72 million yuan [3] - Other stocks like Watson Bio (300142) and Hualan Bio (002007) also experienced significant net inflows from institutional investors, indicating positive sentiment [3] - Conversely, stocks like Dongbao Biological (300239) and Bohui Innovation (300318) faced net outflows from retail investors, suggesting mixed investor sentiment [3]

Core Viewpoint - The company, Rongchang Biopharmaceutical (Yantai) Co., Ltd., is set to hold a third-quarter earnings presentation on December 3, 2025, to discuss its operational results and financial status for Q3 2025, allowing investors to engage in a Q&A session [2][3][4]. Group 1: Meeting Details - The earnings presentation will take place on December 3, 2025, from 13:00 to 14:00 [2][4]. - The venue for the meeting is the Shanghai Stock Exchange Roadshow Center, and it will be conducted in an interactive online format [2][4][5]. - Investors can submit questions from November 26, 2025, to December 2, 2025, before 16:00, either through the Roadshow Center website or via the company's email [2][5]. Group 2: Company Representatives - Key representatives attending the meeting include the Chairman, Mr. Wang Weidong, and the General Manager, Mr. Fang Jianmin [4]. - The meeting will also feature the company’s Board Secretary, Mr. Wen Qingkai, and the Chief Financial Officer, Mr. Tong Shaojing [4]. Group 3: Investor Participation - Investors can participate in the earnings presentation by logging into the Shanghai Stock Exchange Roadshow Center [5]. - After the meeting, the main content and proceedings will be available for review on the Roadshow Center's website [5].

荣昌生物制药（烟台）股份有限公司 股东会会议资料 荣昌生物制药（烟台）股份有限公司 2025 年第三次临时股东会 会议资料 股票简称：荣昌生物 股票代码：688331 2025 年 12 月 荣昌生物制药（烟台）股份有限公司 股东会会议资料 荣昌生物制药（烟台）股份有限公司 会议资料目录 三、会议议案 2 一、会议须知 二、会议议程 1、议案一：《关于预计 2026-2028 年度日常关联交易的议案》 2、议案二：《关于修订公司部分治理制度的议案》 荣昌生物制药（烟台）股份有限公司 股东会会议资料 1 荣昌生物制药（烟台）股份有限公司 2025 年第三次临时股东会会议须知 为了维护全体股东的合法权益，确保股东会的正常秩序和议事效率，保证 会议的顺利进行，根据《中华人民共和国公司法》（以下简称"《公司 法》"）、《中华人民共和国证券法》（以下简称"《证券法》"）、中国证监 会《上市公司股东会规则》以及《荣昌生物制药（烟台）股份有限公司章程》、 《荣昌生物制药（烟台）股份有限公司股东会议事规则》的相关规定，特制定 本会议须知： 一、为确认出席会议的股东或其代理人或其他出席者的出席资格，会议工 作人员将对出席会议者 ...

| 证券代码：688331 | 证券简称：荣昌生物 | 公告编号：2025-052 | | --- | --- | --- | | 港股代码：09995 | 港股简称：榮昌生物 | | 荣昌生物制药（烟台）股份有限公司 关于召开 2025 年第三季度业绩说明会的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 会议召开时间：2025 年 12 月 03 日 （星期三） 13:00-14:00 会议召开方式：上证路演中心网络互动 投资者可于 2025 年 11 月 26 日（星期三）至 12 月 02 日（星期二）16:00 前登录上证路演中心网站首页点击"提问预征集"栏目或通过公司邮箱 ir@remegen.com 进行提问。公司将在说明会上对投资者普遍关注的问题进行回 答。 荣昌生物制药(烟台)股份有限公司（以下简称"公司"）已于 2025 年 10 月 31 日发布公司 2025 年第三季度报告，为便于广大投资者更全面深入地了解公司 2025 年第三季度经营成果、财务状况，公司计划于 2025 年 12 ...

Group 1 - The report highlights the "engineer dividend" period for China's innovative drug industry, indicating that local innovations have gained full recognition from multinational corporations (MNCs) [4][5][53] - The report emphasizes the strong performance of various Chinese biotech stocks, with notable price increases observed in companies like Rongchang Biopharmaceutical (+199%) and Mawei Biopharmaceutical (+124%) in the A-share market [4][16] - The report identifies a significant increase in the number of first-in-class (FIC) drugs entering clinical trials in China, from only 9 in 2015 to an expected 120 in 2024, with China's global share of FIC drugs exceeding 30% [4][22] Group 2 - The report discusses the leading position of Chinese companies in the antibody-drug conjugate (ADC) sector, with over 50% global pipeline share in key targets such as HER2 and TROP2 [25][32] - It notes that two Chinese ADC drugs have entered the top ten global upfront payment rankings, indicating strong valuation potential for local innovations [30][31] - The report highlights the anticipated growth in bispecific antibodies (bsAbs), with Chinese companies dominating the top five global upfront payments for related assets [37][41] Group 3 - The report recommends several companies with significant global single product potential, including Kolon Biotech and Innovent Biologics, while also highlighting others like 3SBio and BeiGene as companies to watch [6][52] - It emphasizes the potential for substantial global pricing power for assets, particularly for companies like Rongchang Biopharmaceutical and Zai Lab, which are expected to see continued clinical data readouts [6][52] - The report suggests that companies like Innovent Biologics and Rongchang Biopharmaceutical are likely to turn profitable, with expectations of improved financial performance in the coming years [6][52]

Core Viewpoint - The A-share market experienced fluctuations with the Sci-Tech Innovation Drug sector continuing to weaken, as evidenced by the Huatai-PineBridge Sci-Tech Innovation Drug ETF (589120) declining by 1.5% for four consecutive days, while still attracting over 13 million yuan in investments over the last two days [1][3][5]. Group 1: Market Performance - The Huatai-PineBridge Sci-Tech Innovation Drug ETF (589120) has seen a significant drop in its component stocks, with major companies like Rongchang Bio and Borui Pharma falling over 2%, while TeBao Bio and HaoYuan Pharma showed gains [3][4]. - The index for the Sci-Tech Innovation Drug ETF has had a remarkable year, with a peak increase of 98.84% as of September 5, reflecting the transformation of China's innovative drug industry over the past decade [5][6]. Group 2: Investment Trends - Despite the recent downturn, the ETF has managed to attract substantial capital, indicating ongoing investor interest in the sector [1][5]. - The market is currently in a performance vacuum following the earnings season, with rapid rotations observed, suggesting a trading-driven rather than a fundamental-driven adjustment in the innovative drug sector [5][8]. Group 3: Financial Performance - The innovative drug sector reported a revenue of 48.83 billion yuan for the first three quarters of 2025, marking a 22.1% increase, while the net profit showed a significant turnaround with a 147.1% increase in Q3 alone [8][10]. - The growth in revenue is attributed to the rapid commercialization of innovative drug products, increased sales, and milestone payments from licensing agreements [10]. Group 4: Future Outlook - The domestic innovative drug sector is witnessing a surge in overseas licensing deals, with 175 transactions amounting to over 104.2 billion USD, indicating a robust pipeline for future growth [7][8]. - The combination of policy support, innovation upgrades, and the normalization of overseas business development (BD) is expected to sustain high growth in the innovative drug sector [10].

Core Insights - The biopharmaceutical sector experienced a decline of 0.98% on November 18, with He Yuan Bio leading the drop [1] - The Shanghai Composite Index closed at 3939.81, down 0.81%, while the Shenzhen Component Index closed at 13080.49, down 0.92% [1] Stock Performance Summary - Notable gainers included: - Aopu Mai (688293) with a closing price of 58.80, up 3.38% on a trading volume of 15,900 shares and a transaction value of 93.39 million [1] - Jin Hu Ke (688670) at 26.80, up 2.88% with a volume of 116,300 shares and a transaction value of 319 million [1] - Te Bao Bio (688278) at 77.08, up 1.22% with a volume of 10,800 shares and a transaction value of 82.57 million [1] - Notable decliners included: - Bu Yuan Bio (688765) at 79.95, down 3.89% with a volume of 56,800 shares and a transaction value of 458 million [2] - San Sheng Guo Jian (688336) at 67.60, down 3.87% with a volume of 68,100 shares and a transaction value of 469 million [2] - Wo Wu Bio (300357) at 31.77, down 3.23% with a volume of 77,900 shares and a transaction value of 250 million [2] Capital Flow Analysis - The biopharmaceutical sector saw a net outflow of 981 million from institutional investors, while retail investors contributed a net inflow of 819 million [2] - Key stocks with significant capital flow included: - Hua Lan Vaccine (301207) with a net inflow of 48.51 million from institutional investors [3] - Rong Chang Bio (688331) with a net inflow of 23.62 million from institutional investors [3] - Jin Ke (688670) with a net inflow of 5.53 million from institutional investors [3]

Core Viewpoint - Jianyin International has raised the target price for Rongchang Biologics (09995) by 9% from HKD 110 to HKD 120, maintaining an "outperform" investment rating [1] Revenue Forecast - Jianyin International has kept its revenue forecasts for Rongchang Biologics for 2025, 2026, and 2027 unchanged at RMB 2.8 billion, RMB 3.4 billion, and RMB 4.6 billion respectively [1] Loss Adjustments - Due to improved operational efficiency, the ratio of operating expenses to sales has decreased, leading to a downward adjustment of the 2025 adjusted net loss forecast from RMB 347 million to RMB 68 million [1] - The 2026 adjusted net loss forecast has also been revised down from RMB 182 million to RMB 94 million [1] Profit Forecast - The adjusted profit forecast for 2027 has been increased from RMB 923 million to RMB 960 million [1]