Group 1 - Kaichun Co., Ltd. adjusted the share repurchase price limit from 26.625 yuan/share to 40 yuan/share, effective from June 10, 2025 [1] - Yipin Pharmaceutical's subsidiary received a drug registration certificate for Dexmedetomidine Hydrochloride Injection, a Class 3 chemical drug used for sedation during anesthesia [1] - Bohui Innovation obtained a medical device registration certificate for HPV Genotyping Test Kit, used for qualitative detection of HPV DNA [1][2] Group 2 - Lingyi Zhi Zao's application for issuing convertible bonds and cash payment to acquire 66.46% of Jiangsu Kedasiteng Automotive Technology Co., Ltd. has been accepted by the Shenzhen Stock Exchange [3] - Kemin Food reported a 23.06% year-on-year increase in pig sales in May, with a total of 48,300 pigs sold [4][5] - Meian Sen decided to terminate the issuance of shares to specific objects due to market conditions and strategic considerations [6][7] Group 3 - Zhengbang Technology reported a 146.6% year-on-year increase in pig sales revenue in May, totaling 731 million yuan [9] - Yuanda Holdings plans to reduce the registered capital of its subsidiary from 73 million to 24.3 million USD to optimize asset structure [10] - East China Pharmaceutical's subsidiary received FDA approval for clinical trials of HDM1010 tablets for type 2 diabetes [12] Group 4 - Liangxin Co., Ltd. received a government subsidy of 14.1 million yuan, accounting for 4.52% of its audited net profit for 2024 [13] - Erkang Pharmaceutical's Vitamin B6 Injection passed the consistency evaluation for generic drugs [14] - New Industry received a patent certificate for an antibody related to anti-PIC detection, enhancing detection efficiency [16][15] Group 5 - Dongxing Medical signed a 6 million yuan technology development contract with Shanghai Jiao Tong University for collagen preparation processes [16] - Suchang Chai A's subsidiary will absorb and merge another subsidiary, adjusting internal equity structure [17] - Yibin Technology received a project designation notice from a domestic new energy vehicle company, with an estimated total sales of 256 million yuan over five years [18] Group 6 - Mingchen Health received a cash dividend of 20 million yuan from its subsidiary [19] - Hendi Pharmaceutical obtained a drug registration certificate for Ibuprofen Suspension, a common medication for children [19] - Huaren Pharmaceutical's subsidiary received a drug registration certificate for Dexmedetomidine Hydrochloride Injection, classified as a Category B drug under national medical insurance [20] Group 7 - Enwei Pharmaceutical obtained a renewed drug production license for six key products [21] - Xiaoming Co., Ltd. reported a 45.59% year-on-year increase in chicken product sales in May, totaling 23.25 million birds [23][24] - Shan Natural Gas successfully issued a 350 million yuan short-term financing bond with a 1.78% interest rate [25] Group 8 - Xidamen announced plans for board members to reduce their holdings by up to 581,000 shares [26] - Shentong Technology's shareholder plans to reduce holdings by up to 3% of the company's shares [27] - Saintno Bio plans to distribute a cash dividend of 0.14 yuan per share and a capital increase of 0.4 shares per share [28] Group 9 - *ST King Kong's subsidiary received a debt transfer notice from its controlling shareholder, totaling 364 million yuan [29] - Foxit Software's executives plan to reduce their holdings by a total of 55,800 shares [30] - Youyou Green Energy plans to apply for a bank credit line of up to 1.5 billion yuan [31] Group 10 - Guoxing Optoelectronics plans to distribute a cash dividend of 0.5 yuan per 10 shares [32] - Guangxun Technology plans to distribute a cash dividend of 2.6 yuan per 10 shares [33] - Hanrui Cobalt plans to distribute a cash dividend of 1.5 yuan per 10 shares [35] Group 11 - Tigermed plans to distribute a cash dividend of 3 yuan per 10 shares [37] - Shenliang Holdings plans to distribute a cash dividend of 1.5 yuan per 10 shares [38] - Yishitong plans to distribute a cash dividend of 1 yuan per 10 shares [39]

证券代码：300723 证券简称：一品红 公告编号：2025-041 一品红药业集团股份有限公司 关于全资子公司获得盐酸右美托咪定注射液注册证书的公告 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚 假记载、误导性陈述或重大遗漏。 一品红药业集团股份有限公司（以下简称"公司"）全资子公司广州一品红 制药有限公司于近日收到国家药品监督管理局核准签发的关于盐酸右美托咪定 注射液的《药品注册证书》，现将有关事项公告如下： 一、药品注册证书主要信息 药品通用名称：盐酸右美托咪定注射液 英文名/拉丁名：Dexmedetomidine Hydrochloride Injection 主要成份：盐酸右美托咪定 剂 型：注射剂 注册分类：化学药品 3 类 规 格：2ml:0.2mg（按 C13H16N2计） 药品注册标准编号：YBH12292025 药品有效期：24 个月 上市许可持有人：广州一品红制药有限公司 上市许可持有人地址：广州市经济技术开发区东区东博路 6 号 生产企业：河北凯威制药有限责任公司 生产企业地址：河北省张家口市宣化县沙岭子镇（东山产业集聚区） 药品批准文号：国药准字 H2025441 ...

Core Viewpoint - The company has received approval from the National Medical Products Administration for the drug registration of Dexmedetomidine Hydrochloride Injection, indicating a significant advancement in its product portfolio [1] Group 1: Company Developments - The company's wholly-owned subsidiary, Guangzhou Yipinhong Pharmaceutical Co., Ltd., has been granted a drug registration certificate for Dexmedetomidine Hydrochloride Injection [1] - The main ingredient of the drug is Dexmedetomidine Hydrochloride, and it is formulated as an injection with a specification of 2ml:0.2mg (calculated as C13H16N2) [1] - The registration classification for this drug is categorized as Class 3 chemical drugs [1]

Investment Rating - The report maintains a "Recommended" rating for the pharmaceutical industry [1] Core Insights - The revaluation of innovative drugs continues, driven by significant transactions and a trend towards differentiation in the market. The value of innovative drugs is increasingly recognized by multinational corporations (MNCs), particularly in the areas of EGFR and PD-1 dual antibodies. The number of pharmaceutical transactions in China increased by 34% year-on-year in Q1 2025, with total transaction value rising by 222% [3] - The upcoming ADA conference presents opportunities for Chinese companies to showcase their research, particularly in the areas of diabetes and weight loss. Notable collaborations and developments in GLP-1 drugs are expected to enhance the market presence of Chinese firms [4] - The gout treatment market shows significant potential, with a projected increase in patients from 170 million in 2020 to 240 million by 2030 in China. New drugs targeting URAT1 are entering critical clinical stages, indicating a strong market opportunity for innovative treatments [5] - Chinese companies are leading breakthroughs in CAR-T technology, with key developments expected in 2025. Recent clinical trials have shown promising results for CAR-T therapies in treating various cancers, indicating a strong future for these innovations [6] Summary by Sections 1. Pharmaceutical Market Tracking - The pharmaceutical industry outperformed the CSI 300 index by 0.25% in the past week, with a weekly increase of 1.13% [17] - Over the past month, the pharmaceutical sector's index rose by 6.48%, surpassing the CSI 300 index by 4.76%, ranking second among all sectors [22] 2. Pharmaceutical Sector Trends and Valuation - The pharmaceutical sector's current PE (TTM) is 34.41, slightly above the five-year historical average of 32.55 [41] 3. Recent Research Achievements - The research team has published several in-depth reports highlighting the growth trends in the blood products industry and the impact of policies on inhalation drug markets [44] 4. Recent Industry Policies and News - Recent policies aim to enhance the pricing and procurement evaluation system in the pharmaceutical sector, promoting a fair and transparent market environment [47] - Notable industry news includes several innovative drugs receiving clinical trial approvals and partnerships between Chinese companies and international firms, indicating a vibrant and evolving market landscape [48][49]

证券代码：300723 证券简称：一品红 公告编号：2025-039 一品红药业集团股份有限公司 关于全资子公司获得间苯三酚注射液注册证书的公告 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚 假记载、误导性陈述或重大遗漏。 一品红药业集团股份有限公司（以下简称"公司"）全资子公司广州市联瑞 制药有限公司于近日收到国家药品监督管理局核准签发的关于间苯三酚注射液 的《药品注册证书》，现将有关事项公告如下： 一、药品注册证书主要信息 药品通用名称：间苯三酚注射液 英文名/拉丁名：Phloroglucinol Injection 主要成份：间苯三酚 剂 型：注射剂 注册分类：化学药品 4 类 规 格：4ml:40mg（按 C6H6O3•2H2O 计） 药品注册标准编号：YBH10562025 药品有效期：18 个月 申请事项：药品注册（境内生产） 包装规格：10 支/盒 审批结论：根据《中华人民共和国药品管理法》及有关规定，经审查，本品 符合药品注册的有关要求，批准注册，发给药品注册证书。质量标准、说明书、 标签及生产工艺照所附执行。药品生产企业应当符合药品生产质量管理规范要求 方可生产销售。 上 ...

一品红药业集团股份有限公司 关于全资子公司获得羧甲司坦口服溶液注册证书的公告 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚 假记载、误导性陈述或重大遗漏。 一品红药业集团股份有限公司（以下简称"公司"）全资子公司广州市联瑞 制药有限公司于近日收到国家药品监督管理局核准签发的关于羧甲司坦口服溶 液的《药品注册证书》，现将有关事项公告如下： 一、药品注册证书主要信息 药品通用名称：羧甲司坦口服溶液 英文名/拉丁名：Carbocysteine Oral Solution 证券代码：300723 证券简称：一品红 公告编号：2025-040 主要成份：羧甲司坦 剂 型：口服溶液剂 注册分类：化学药品 3 类 规 格：125ml:2.5g 药品注册标准编号：YBH11032025 药品有效期：18 个月 申请事项：药品注册（境内生产） 包装规格：每盒 1 瓶 处方药/非处方药：处方药 审批结论：根据《中华人民共和国药品管理法》及有关规定，经审查，本品 符合药品注册的有关要求，批准注册，发给药品注册证书。质量标准、说明书、 标签及生产工艺照所附执行。药品生产企业应当符合药品生产质量管理规范要求 方可生 ...

截至6月3日收盘，重组蛋白概念上涨3.64%，位居概念板块涨幅第3，板块内，45股上涨，*ST万方涨 停，诺思兰德、科兴制药、海特生物等涨幅居前，分别上涨18.82%、14.97%、13.18%。跌幅居前的有 *ST苏吴、博瑞医药、西陇科学等，分别下跌4.78%、2.48%、1.42%。 今日涨跌幅居前的概念板块 | 概念 | 今日涨跌幅（%） | 概念 | 今日涨跌幅（%） | | --- | --- | --- | --- | | 中韩自贸区 | 4.23 | 特钢概念 | -0.93 | | 细胞免疫治疗 | 3.87 | 医疗废物处理 | -0.51 | | 重组蛋白 | 3.64 | 果指数 | -0.41 | | 足球概念 | 3.56 | 无线充电 | -0.39 | | 毛发医疗 | 3.51 | 光热发电 | -0.33 | | CRO概念 | 3.41 | 深圳国企改革 | -0.24 | | 创新药 | 3.38 | F5G概念 | -0.23 | | 培育钻石 | 3.11 | 租售同权 | -0.22 | | 仿制药一致性评价 | 3.08 | 一体化压铸 | -0.21 | | 眼 ...

| 股票简称 | 股票代码 | 限售股类型 | 解禁股数 | | --- | --- | --- | --- | | 新大洲A | 000571 | 股权激励限售流通 | 980.75万 | | 中钨高新 | 000657 | 股权激励限售流通 | 72.06万 | | 东方钽业 | 000962 | 股权激励限售流通 | 156.87万 | | 内蒙一机 | 600967 | 股权激励限售流通 | 663.31万 | | 三花智控 | 002050 | 股权激励限售流通 | 701.47万 | | 大禹节水 | 300021 | 股权激励限售流通 | 76.17万 | | 瑞普生物 | 300119 | 股权激励限售流通 | 69.76万 | | 海南矿业 | 601969 | 股权激励限售流通 | 364.05万 | | 吉翔股份 | 603399 | 股权激励限售流通 | 309万 | | 华电重工 | 601226 | 股权激励限售流通 | 388.82万 | | 星徽股份 | 300464 | 股权激励限售流通 | 576万 | | 博济医药 | 300404 | 股权激励限售流通 | 20万 | ...

Group 1 - The report indicates that in June, overseas focus is on tariff negotiations, debt risks, and interest rate cut expectations, leading to a cautious outlook for US stocks, while domestic economic and policy observations show limited incremental highlights [3][11] - The A-share market is expected to experience range-bound fluctuations, with a continuation of the "barbell strategy" focusing on dividend defense, domestic demand recovery, and technology growth [3][15] - The report highlights the importance of monitoring sectors such as banking, public utilities, transportation, new consumption, innovative pharmaceuticals, agriculture, and technology-driven industries like AI and semiconductors for potential investment opportunities [3][15] Group 2 - The report lists the top ten stocks for June, including companies from various sectors such as electronics, media, automotive, chemicals, pharmaceuticals, food and beverage, and power equipment [4][10] - Specific companies highlighted include Lianchuang Optoelectronics, Juguang Technology, and Changchun Gaoxin, with each showing promising growth potential based on recent performance and market conditions [4][17][27] - The report provides earnings forecasts for these companies, indicating expected revenue growth for Lianchuang Optoelectronics from 32.91 billion to 45.04 billion from 2025 to 2027, and for Juguang Technology from 5.65 billion to 11.01 billion in the same period [21][27]

Core Viewpoint - The company has successfully obtained the production license for the innovative gout drug AR882, indicating that its production capabilities meet national drug standards and regulatory requirements, which supports the drug's future market launch [1] Group 1: Company Developments - The subsidiary Guangdong Ruishi Pharmaceutical Technology Co., Ltd. has passed the comprehensive review by the Guangdong Provincial Drug Administration and obtained the production license for the active pharmaceutical ingredient (API) deuterated probenecid (AR882) [1] - The innovative API base of Ruishi Pharmaceutical is designed according to international standards such as FDA and EU GMP, covering an area of 110 acres with over 50,000 square meters of constructed area and multiple advanced production lines [1] - The production workshop for AR882 utilizes fully enclosed automated production equipment, achieving industry-leading standards in China [1] Group 2: Product Information - AR882 is a next-generation, highly selective URAT1 inhibitor that promotes uric acid excretion and prevents renal toxicity, with a once-daily dosage to maintain healthy serum uric acid levels [2] - The drug has received Fast Track Designation (FTD) from the FDA for gout stone research, potentially filling a global gap in oral medications for gout stone treatment [2] - The global prevalence of hyperuricemia and gout is projected to reach 1.42 billion by 2030, with approximately 200 million individuals affected in China, indicating a significant clinical demand for effective treatments [2] Group 3: Clinical Progress - AR882 has enrolled over a thousand participants globally in its Phase III clinical trials, showing promising efficacy in three key areas: precise acid control, dissolution of gout stones, and safety without renal toxicity [3] - The company has agreed to acquire the remaining 15.25% stake in its subsidiary Guangzhou Ruianbo from Arthrosi for approximately 6.8 million USD, increasing its ownership to 100% to enhance its market position for AR882 in China [3]