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2025年药品BD出海回顾:显著提速,关注双抗、ADC、GLP-1RA、小核酸等方向
Southwest Securities· 2026-01-26 00:45
Investment Rating - The report indicates a "Buy" rating for several companies within the pharmaceutical sector, including 恒瑞医药 (Hengrui Medicine), 百济神州-U (BeiGene), and others [22]. Core Insights - The pharmaceutical industry has seen a significant increase in BD (business development) activities, with Chinese pharmaceutical companies securing upfront payments exceeding $7.03 billion in 2025, marking a year-on-year growth of over 226.8% [15][20]. - The industry has a total market capitalization of approximately 544.85 billion yuan, with a TTM (trailing twelve months) P/E ratio of 38.5, significantly higher than the 14.1 P/E ratio of the CSI 300 index [3][6]. - The best-performing sub-sectors this week include offline pharmacies, hospitals, and medical R&D outsourcing, with year-to-date increases of 17.2%, 14.8%, and 10.7%, respectively [6][31]. Summary by Sections Industry Performance - The pharmaceutical index decreased by 0.39% this week, outperforming the CSI 300 index by 0.23 percentage points. Year-to-date, the pharmaceutical sector has risen by 6.66%, surpassing the CSI 300 index by 5.10 percentage points [6][24]. - The current valuation level (P/E-TTM) for the pharmaceutical industry stands at 30.31 times, with a premium of 65.36% over the entire A-share market [6][26]. Business Development Trends - In 2025, the domestic dual-antibody BD projects achieved upfront payments of $3.5 billion, a staggering increase of 414.7%, accounting for 49.8% of all BD upfront payments for the year [16]. - The ADC (Antibody-Drug Conjugates) sector has also seen substantial growth, with upfront payments reaching $1.63 billion, a 676.2% increase year-on-year [17]. - The GLP-1RA (Glucagon-Like Peptide-1 Receptor Agonists) segment reported upfront payments of $470 million, reflecting a 109.8% increase compared to 2024 [18]. Notable Collaborations - The report highlights significant collaborations, such as 舶望制药 (Bohua Pharmaceutical) partnering with Novartis to explore the potential of siRNA in hypertension treatment, securing an upfront payment of $160 million [19]. - The MNC (Multinational Corporation) procurement model remains dominant, with local companies securing $4.71 billion in upfront payments from MNCs, representing 67.0% of total BD upfront payments [20]. Recommended Companies - The report suggests a robust investment strategy focusing on companies like 恒瑞医药 (Hengrui Medicine), 百济神州-U (BeiGene), and others, which are expected to benefit from innovation and international expansion [20][21].
汽车行业2026年投资策略:汽车出海迈入深水区,智能化&机器人大展宏图
Southwest Securities· 2026-01-23 12:34
Investment Rating - The report provides a positive investment outlook for the automotive industry, particularly focusing on smart vehicles, new energy vehicles, commercial vehicles, and humanoid robots, indicating significant growth potential in these sectors [1][2]. Core Insights - The automotive industry is entering a transformative phase driven by policies that support the development of smart vehicles and the expansion of new energy vehicles. The report highlights the acceleration of intelligent driving technology and the increasing market penetration of new energy vehicles [3][4]. Summary by Relevant Sections Smart Vehicles - The report emphasizes that the intelligent vehicle sector is experiencing rapid advancements due to policy support, with L3 vehicle standards expected to be implemented by 2026. The adoption of advanced driving assistance systems (ADAS) is increasing, with new vehicle models showing significant growth in features like highway and urban NOA (Navigation on Autopilot) [4][68]. - The financing landscape for autonomous driving is booming, with 35 companies in the sector raising over 582 billion yuan in 2025, nearly three times the amount raised in 2023 [4][80]. New Energy Vehicles - The continuation of vehicle replacement policies is expected to bolster sales, with wholesale volumes of new energy passenger vehicles projected to reach 18.16 million units in 2026, a year-on-year increase of 18% [4][34]. - Exports of new energy vehicles have shown remarkable growth, with a 102.5% year-on-year increase in 2025, indicating strong demand in international markets [4][34]. Commercial Vehicles - The heavy truck sector is supported by ongoing vehicle replacement policies, with sales expected to reach 1.196 million units in 2026, reflecting a year-on-year growth of 4.6% [4][34]. - The report notes that the heavy truck market is benefiting from both domestic and international demand, with significant growth anticipated due to the continued penetration of new energy heavy trucks [4][34]. Humanoid Robots - The humanoid robot sector is poised for rapid growth, with applications in automotive manufacturing expected to enhance production efficiency. The report forecasts a compound annual growth rate of approximately 85% in humanoid robot shipments from 2024 to 2035 [4][34]. - The cost of humanoid robots is expected to decrease significantly, with projections indicating that the price of a standard humanoid robot could drop from $80,000-$90,000 to $15,000-$20,000 by 2030 [4][34]. Policy Environment - The report highlights a favorable policy environment that is increasingly supportive of the automotive industry's transition towards smart and electric vehicles. Key policies include the approval of L3 autonomous vehicle models and the establishment of unified standards for vehicle replacement subsidies [4][53]. Market Trends - The automotive market is witnessing a shift towards intelligent and electric vehicles, with consumer preferences evolving towards higher levels of automation and connectivity in vehicles. The report indicates that the penetration rate of intelligent driving features is expected to increase significantly in the coming years [4][68]. Capital Market Activity - The report notes a surge in investment activity within the autonomous driving sector, indicating a strong belief in the future growth of this industry. The capital market's enthusiasm is reflected in the substantial funding raised by various companies, signaling a robust outlook for the sector [4][80].
国内财政支出加力,美欧摩擦不断
Southwest Securities· 2026-01-23 10:41
Domestic Economic Outlook - The IMF has raised China's GDP growth forecasts for 2025 and 2026 by 0.2% and 0.3% to 5% and 4.5% respectively, citing improved external trade conditions and robust growth in emerging industries like AI[8] - The Chinese government has committed to increasing fiscal spending in 2026, with a focus on policies to boost domestic demand through lower credit costs and support for private investment[10] - In 2025, China's industrial output increased by 5.9%, with high-tech manufacturing growing by 9.4%, indicating a stable industrial economy[12] International Economic Developments - Japan's 40-year bond yield has surpassed 4% for the first time, raising concerns about fiscal sustainability following the announcement of expansionary fiscal policies[16] - The U.S. housing market faced a significant downturn, with December's existing home sales index dropping 9.3%, marking the largest decline since the pandemic began[20] - Tensions between the U.S. and Europe escalated over tariffs related to Greenland, impacting market stability and leading to a surge in gold and silver prices[18] Commodity Price Trends - Brent crude oil prices fell by 0.15% week-on-week, while iron ore and copper prices decreased by 3.67% and 2.17% respectively[24] - In emerging industries, prices for lithium iron phosphate rose by 11.52%, while prices for hexafluorophosphate lithium decreased by 3.97%[24]
有色金属行业2026年投资策略:资源大周期,把握金属全面牛市
Southwest Securities· 2026-01-23 10:36
Core Insights - The report highlights a bullish outlook for the metals sector, driven by macroeconomic factors such as the Federal Reserve's interest rate cuts and a recovering global economy, particularly in China [3][44] - Key investment themes for 2026 include expanding demand for precious metals like gold and silver, improving fundamentals for aluminum and copper, strategic opportunities in rare earths, and supply-side disruptions due to overcapacity in certain sectors [3][4] Group 1: Precious Metals - The report suggests a long-term bullish view on gold, with expectations of price increases driven by anticipated interest rate cuts and geopolitical tensions, which enhance gold's appeal as a safe-haven asset [3][44] - Silver is also highlighted as a key investment opportunity due to its high price ratio to gold, indicating potential for significant price appreciation [3] - Specific companies to watch include Shandong Gold (600547.SH) and Zijin Mining (601899.SH), which are expected to benefit from increased production and operational efficiencies [4] Group 2: Industrial Metals - The report notes that aluminum and copper are set to see improved profitability due to lower production costs and increased demand, particularly in the context of infrastructure investments [3][4] - Companies such as Zhongfu Industrial (600595.SH) and Zijin Mining (601899.SH) are identified as having strong positions in the copper market, with expected profit growth [4] - The report emphasizes the importance of monitoring supply chain dynamics, particularly in copper, where inventory levels are shifting significantly [18][58] Group 3: Rare Earths and Strategic Metals - The report identifies rare earth elements as a critical area for investment, particularly in light of geopolitical tensions between the US and China, which may create opportunities for companies involved in rare earth mining and processing [3][4] - Companies like Northern Rare Earth (600111.SH) and China Rare Earth (000831.SZ) are highlighted for their potential to benefit from price increases in rare earth materials [4] Group 4: Energy Metals - The report discusses the rebound in lithium and nickel prices, driven by strong demand from the battery sector, with specific mention of companies like Tianqi Lithium (002466.SZ) and Ganfeng Lithium (002460.SZ) [4][27] - The expected growth in energy storage solutions is also noted as a significant driver for demand in these metals [4] Group 5: Overall Market Performance - The overall performance of the non-ferrous metals sector is noted to have outperformed the broader market, with a cumulative increase of 96.46% in 2025 compared to a 21.65% increase in the Shanghai Composite Index [33][35] - The report indicates that while the sector has seen significant gains, valuations are currently at historical averages, suggesting potential for further growth [35]
医疗设备以旧换新专题系列六:12月数据同比-8%,25年全年同比+25%
Southwest Securities· 2026-01-23 10:36
Investment Rating - The report indicates a positive outlook for the medical equipment industry, with an expected year-on-year growth of 25% for the year 2025 [22]. Core Insights - The medical equipment industry is experiencing a slight decline in December data year-on-year, attributed to a high base effect from the previous year. However, there is a significant month-on-month increase of 38% due to accelerated budget spending at year-end [3]. - The report highlights that the current round of medical equipment upgrades is nearing its end, with expectations for a new round of equipment replacement in 2025, which is projected to be no less than the previous round [4]. - The report emphasizes the importance of government policies, including the issuance of long-term special bonds to support large-scale equipment upgrades and consumer replacement programs [15]. Summary by Relevant Sections Medical Imaging - December figures for medical imaging reached 9.8 billion yuan, a decrease of 11%, while the forecast for 2025 is 69.3 billion yuan, reflecting a growth of 37% [5]. Life Information and Support - In December, life information and support equipment generated 2.6 billion yuan, an increase of 8%, with a projected total of 16.7 billion yuan for 2025, marking a 28% growth [5]. Endoscopes - Soft endoscopes reported 1.1 billion yuan in December, down 9%, while hard endoscopes reached 1.2 billion yuan, down 7%. The 2025 projections for both are 7.8 billion yuan for soft endoscopes (+12%) and 7.8 billion yuan for hard endoscopes (+3%) [5]. Radiation Therapy - December figures for radiation therapy stood at 1.6 billion yuan, a slight increase of 1%, with a forecast of 9.6 billion yuan for 2025, indicating a growth of 32% [48]. Surgical Robots - Surgical robots saw a significant decline in December, with figures at 600 million yuan, down 24%, but are expected to reach 5.2 billion yuan in 2025, reflecting a robust growth of 54% [51]. Key Companies - Major companies in the sector include Mindray, which reported 1.9 billion yuan in December (+20%) and is projected to reach 11.2 billion yuan in 2025 (+35%), and United Imaging, with December figures of 2.2 billion yuan (0% change) and a forecast of 12.6 billion yuan (+37%) for 2025 [55][58].
汽车行业2026年投资策略:汽车出海迈入深水区,智能化、机器人大展宏图
Southwest Securities· 2026-01-23 10:36
Core Insights - The automotive industry is entering a critical phase of globalization, with significant advancements in smart technology and robotics expected to drive growth [1][4] - The report highlights the acceleration of smart vehicle development due to favorable policies, technological convergence, and increased consumer demand for intelligent features [4][68] Smart Vehicles - Policy support is enhancing the development of smart driving technologies, with L3 vehicle standards expected to be implemented by 2026, facilitating the growth of the autonomous driving industry [4][53] - The adoption of advanced driver-assistance systems (ADAS) is increasing, with new vehicle models showing a significant rise in the installation rates of highway NOA and urban NOA, reaching 30.20% and 34.82% respectively in early 2025 [4][79] - The capital market is witnessing explosive growth in autonomous driving financing, with 35 companies raising over 582 billion yuan in 2025, nearly three times the amount raised in 2023 [4][80] New Energy Vehicles - The continuation of vehicle replacement policies is expected to support sales, with wholesale volumes of new energy passenger vehicles projected to reach 18.16 million units in 2026, a year-on-year increase of 18% [4] - Exports of new energy vehicles showed robust growth, with 2.238 million units exported from January to November 2025, marking a 102.5% increase year-on-year [4] Commercial Vehicles - Heavy truck sales are supported by ongoing replacement policies and expected to reach 1.196 million units in 2026, reflecting a year-on-year growth of 4.6% [4] Humanoid Robots - The humanoid robot industry is poised for rapid growth, with applications in automotive manufacturing expected to enhance production efficiency [4] - The cost of humanoid robots is projected to decrease significantly, from approximately $80,000-$90,000 to $15,000-$20,000 by 2030, driven by advancements in AI and production scale [4] Policy Environment - The policy landscape is becoming increasingly favorable for the automotive industry, with initiatives aimed at promoting smart and connected vehicles, including the approval of L3 autonomous driving models [4][53] Supply Side Dynamics - Automakers are accelerating the rollout of intelligent driving features, transitioning from high-end options to standard offerings across various price segments, thereby meeting consumer preferences for smart technology [4][68][73]
3D 打印行业系列报告(一):工业级与消费级应用双轮驱动,行业迈入快速发展期
Southwest Securities· 2026-01-23 10:30
Investment Rating - The report maintains an "Outperform" rating for the 3D printing industry as of January 22, 2026 [1] Core Insights - The 3D printing industry is entering a rapid development phase driven by both industrial and consumer applications, with significant market potential projected to reach hundreds of billions [8] - The global additive manufacturing market is expected to grow to $21.9 billion by 2024, with a CAGR of 18% projected until 2034 [8] - Domestic policies in China are increasingly supportive, indicating a maturing industry with substantial growth potential [8] Summary by Sections 1. 3D Printing Technology and Development - Seven core processes facilitate the development of 3D printing across multiple fields, including powder bed fusion and directed energy deposition [16][22] - The technology has evolved from rapid prototyping in the 1980s to widespread commercial applications in various sectors, including aerospace and healthcare [18][20] 2. Industry Growth and Applications - The 3D printing industry is experiencing rapid growth, with applications expanding across various sectors such as aerospace (17.7%), medical (17.6%), and automotive (10.3%) [8][71] - The global market for aerospace 3D printing is projected to reach $2.88 billion by 2025, with a CAGR of 20% until 2035 [8] 3. Market Dynamics and Competitive Landscape - Domestic manufacturers are leading in desktop applications, while industrial-grade 3D printing is seeing increased competition from local firms [8] - Key players in the industrial-grade market include EOS, which holds over 40% market share, followed by other significant companies [8] 4. Investment Opportunities - The report suggests focusing on companies that are well-positioned to benefit from technological advancements and expanding applications, including equipment manufacturers like Huazhu High-Tech and service providers like Jingyan Technology [8]
2025年药品BD出海总结
Southwest Securities· 2026-01-20 11:37
Investment Rating - The report indicates a significant acceleration in BD (Business Development) overseas for Chinese innovative drugs, suggesting a positive investment outlook for the industry [3]. Core Insights - The number of BD projects, upfront payments, and total amounts for Chinese pharmaceutical companies significantly increased in 2025, with 165 projects, over $7.03 billion in upfront payments (up 226.8% year-on-year), and a total amount of $136.68 billion (up 192.2% year-on-year) [2][7]. - The report highlights a focus on dual antibodies (双抗), antibody-drug conjugates (ADC), GLP-1 receptor agonists (GLP1RA), and small nucleic acids as key areas for BD overseas [2][3]. Summary by Sections BD Project Growth - In 2025, the quarterly breakdown of BD projects shows 41, 43, 30, and 51 projects in Q1, Q2, Q3, and Q4 respectively, with significant year-on-year increases [2][7]. - Upfront payments for each quarter were $0.9 billion, $2.0 billion, $1.86 billion, and $2.27 billion, reflecting substantial growth rates [2][7]. Outbound BD Models - The predominant model for BD remains license in/out, while the NewCo/Co-CoJV model is gaining attention, with limited successful cases of independent commercialization [2][12][13]. - In 2025, MNCs (Multinational Corporations) accounted for $4.71 billion in upfront payments, representing 67% of total BD upfront payments [12]. Key Drug Categories - Dual antibodies saw a remarkable increase, with $3.5 billion in upfront payments (up 414.7%) and a total amount of $21.85 billion (up 361.5%) in 2025 [2][18]. - ADCs emerged as a significant focus, with $1.63 billion in upfront payments (up 676.2%) and a total amount of $21.13 billion (up 390.6%) [2][26]. - GLP-1RA projects achieved $470 million in upfront payments, marking a 109.8% increase, with a total amount of $9.6 billion [2]. NewCo Model - The NewCo model has facilitated overseas BD, with a total of $350 million in upfront payments and $13.74 billion in potential total amounts from 2023 to 2025 [17]. - In 2025, NewCo projects secured $110 million in upfront payments and $4.76 billion in potential total amounts [17]. Clinical Development Stages - Approximately 62% of molecules were in early clinical stages (pre-clinical to before Phase II) at the time of BD, indicating a trend towards early-stage licensing [8][9].
食品饮料行业2026年投资策略:白酒有望调整结束,大众品优选个股
Southwest Securities· 2026-01-20 09:16
Core Insights - The report indicates that the adjustment period for high-end liquor is expected to end, highlighting the long-term investment value in this sector. The price of mainstream liquor has decreased from approximately 2200 yuan around the Spring Festival in 2025 to about 1560 yuan currently, with a notable decline since June [4][30][32] - The beer industry is anticipated to benefit from a low base effect in 2026, with emerging retail channels and government consumption stimulus policies expected to drive recovery [5][42] - The dairy industry is currently in a transitional phase, with low milk prices expected to rebound as demand improves and supply stabilizes. The long-term growth potential remains strong due to ongoing consumption upgrades [5][60][63] - The condiment sector is projected to benefit from a gradual recovery in restaurant consumption, with both B2B and B2C channels expected to see improved sales as consumer spending recovers [5][79] Liquor Industry - High-end liquor is expected to stabilize after a period of adjustment, with long-term investment value becoming more apparent. The market share of premium liquor brands continues to rise, and the consumption upgrade trend remains intact despite short-term impacts [4][30][34] - The competition in the mid-range liquor segment has intensified, with brands experiencing varying levels of performance due to market pressures. The demand for mid-range products has been notably affected by weak business consumption [36][39] - Inventory management is crucial, with manufacturers actively controlling supply to maintain price stability. The introduction of information systems has improved inventory management capabilities [40][39] Beer Industry - The beer market is expected to recover due to a low base effect from 2025, with national leaders likely to benefit significantly. The rise of instant retail channels is also anticipated to drive growth in non-on-premise beer sales [42][43] - The industry is entering a mature phase, with a focus on premiumization and product structure upgrades. The market share of high-end products is increasing, reflecting a shift in consumer preferences [47][50] - Cost stability is expected in 2026, with barley prices remaining low and contributing to profit margins. The overall cost structure is anticipated to support profitability in the beer sector [51][53] Dairy Industry - The dairy sector is currently experiencing a down cycle in milk prices, but a rebound is expected as demand improves and supply stabilizes. The long-term growth potential remains strong due to increasing consumer preferences for high-quality dairy products [60][63] - The population base in China supports the demand for dairy products, with significant growth potential in rural areas where consumption is currently lower compared to urban areas [66][70] - The industry is witnessing a shift towards high-quality growth, with leading companies focusing on improving profitability through better cost management and efficiency [60][77] Condiment Industry - The condiment sector is expected to benefit from a gradual recovery in restaurant consumption, with B2B channels likely to see significant improvements as consumer spending increases [79][84] - The industry has shown resilience, with a stable growth rate over the past five years. The market size for condiments has surpassed 650 billion yuan, driven by rising consumer demand and changing eating habits [83][84] - Cost advantages are anticipated in 2026, with raw material prices remaining low, which will help maintain stable growth in the condiment sector [79][80]
可转债类ETF份额逆市增长
Southwest Securities· 2026-01-19 11:45
Report Industry Investment Rating No relevant content provided. Core Viewpoints - The net inflow of bond ETFs showed a structural divergence last week, with the net outflows of interest - rate bond and credit - bond ETFs narrowing, and convertible bond ETFs getting a small net inflow, which may reflect the trend of some funds switching between major asset classes during the adjustment of the equity market [4][7]. - The outflow of funds mainly came from the science - innovation bond ETF, which had a large net outflow for two consecutive weeks after a large - scale inflow at the end of last year [4][8]. - The share of convertible bond ETFs increased significantly, while the share of science - innovation bond ETFs decreased significantly [4][18]. Summary by Directory 1.1 各类债券 ETF 资金净流入情况 - The net inflow of bond ETFs was structurally differentiated. Last week, the net inflows of interest - rate bond, credit - bond, and convertible bond ETFs were - 5.061 billion yuan, - 14.547 billion yuan, and + 1.703 billion yuan respectively, with a total net inflow of - 17.905 billion yuan in the bond ETF market. As of January 16, 2026, the bond ETF fund scale was 747.966 billion yuan, down 2.17% from the previous week's close and 9.78% from the beginning of the year, accounting for 12.31% of the total market ETF scale [7]. - The outflow of funds mainly came from the science - innovation bond ETF, with a net outflow of 8.568 billion yuan last week, followed by the benchmark market - making credit - bond ETF (- 5.023 billion yuan) and the policy - financial bond ETF (- 2.651 billion yuan) [8]. 1.2 各类债券 ETF 份额及代表产品净值走势 - The share of convertible bond ETFs increased by 3.5%, leading other types of bond ETFs, while the total share of bond ETFs decreased by 0.2%. Compared with the end of last month, the total share of bond ETFs decreased by 3.5% [18]. - Last week, the bond market recovered, and the net values of major bond ETFs were boosted. The net values of representative products of various bond ETFs increased by 0.03% - 1.05% compared with the previous week's close [21]. 1.3 基准做市信用债 ETF 份额及净值走势 - The shares of all 8 existing benchmark market - making credit - bond ETFs decreased, with a total decrease of 55.11 million shares compared with the previous week's close [26]. - The net values of all 8 products increased, with an increase of 0.05% - 0.10% compared with the previous week's close [28]. 1.4 科创债 ETF 份额及净值走势 - The shares of science - innovation bond ETFs, which had received a large amount of funds before, flowed out intensively. The net inflow of shares last week was - 84.37 million shares, a decrease of 2.71% from the previous week. The top three products with the largest share outflows were Huatai - PineBridge Science - Innovation Bond ETF, GF Science - Innovation Bond ETF, and Bosera Science - Innovation Bond ETF [31]. - The net values of science - innovation bond ETFs rebounded slightly. The average net values of the first - batch and second - batch science - innovation bond ETFs increased by 0.07% and 0.08% respectively compared with the previous week's close [33]. 1.5 单只债券 ETF 市场表现情况 - Benefiting from the strong bond market, the net values of bond ETF products generally rose. The convertible bond ETF, Shanghai - Stock - Exchange Convertible Bond ETF, and Bosera 30 - Year Treasury Bond ETF led the gains, with increases of 1.05%, 0.68%, and 0.37% respectively [36]. - In terms of the premium/discount rate, the Shanghai - Stock - Exchange Convertible Bond ETF and the convertible bond ETF had the highest premium rates, at 0.04% and 0.02% respectively. In terms of scale change, the Shanghai - Stock - Exchange Convertible Bond ETF (+ 1.561 billion yuan), the convertible bond ETF (+ 0.677 billion yuan), and the short - term financing ETF (+ 0.252 billion yuan) ranked the top three in net inflow [36].