Investment Rating - The industry investment rating is "Positive" [1] Core Viewpoints - The report indicates that the turning point has been reached, and there is optimism regarding the elasticity of the scientific services sector [3][6] - The sector has experienced significant adjustments in funding, and with the combination of fundamental turning points and policy support, a valuation reversal is expected [4] Summary by Sections 1. Funding Situation - As of Q1 2025, the total market value of institutional holdings in the scientific services sector is 3.286 billion, accounting for 0.11% of total fund holdings, indicating a low allocation by institutions [4][12] - From January 1, 2025, to May 7, 2025, the average increase in the scientific services sector was 9%, outperforming the pharmaceutical index by 7.7 percentage points [4][13] 2. Fundamentals - **Revenue**: The average year-on-year revenue growth for core scientific service targets in 2024 is 7.17%, with significant recovery in low-consumption categories [5][23] - **Gross Margin**: The average gross margin for core targets in 2024 is 47.99%, with a gradual recovery expected as cost control and capacity utilization improve [5][25] - **Capital Expenditure**: The total capital expenditure for the sector in 2024 is 4.643 billion, a decrease of 35% year-on-year, indicating a shift towards an investment harvest period [5][29] - **Inventory**: The average inventory turnover rate for core targets in 2024 is 3.7 times, showing an optimization trend [5][39] - **Net Profit Margin**: The average net profit margin for core targets in 2024 is 5.22%, with a slight increase to 5.47% in Q1 2025, indicating a recovery in profitability [5][50] 3. Investment Recommendations - The report recommends focusing on companies with strong growth certainty and clear trends in profitability improvement, highlighting Titan Technology, Haoyuan Pharmaceutical, Bid Medical, and Nanwei Technology as key recommendations [7][53]

Core Viewpoint - Bidder Pharmaceutical, established in 2007, provides specialized and efficient drug molecular building blocks and scientific reagent products and services for new drug research and development. The company focuses on a "more, faster, better, cheaper" core advantage and employs a model of "horizontal expansion of product variety + vertical deepening of advantageous product lines" to serve the new drug development industry chain [2][3]. Industry Overview - Domestic market demand is recovering, with a pressing need for domestic alternatives. Research funding continues to grow, and policies such as U.S. tariffs are pushing downstream sectors to seek domestic alternatives, creating market expansion opportunities for local manufacturers [2][36]. - Overseas demand is rebounding, with a need for breakthroughs in the market. Since the second half of 2023, investment amounts in U.S. biopharmaceuticals have shown improvement, indicating increased demand from overseas pharmaceutical companies and CROs [2][36]. Company Performance - Bidder Pharmaceutical has expanded its inventory to 130,000 types of stock products, offering over 500,000 novel and multifunctional drug molecular building blocks to meet downstream demands [2][82]. - The company has increased its R&D investment, with some products reaching international advanced levels while maintaining price advantages. R&D expenses grew from 13.83 million yuan in 2018 to 59.05 million yuan in 2024, with a CAGR of 27.37% [2][86]. - Bidder's overseas revenue for 2024 is projected to be 616 million yuan, with a gross margin of 50.40%, significantly higher than domestic margins. The company has achieved a CAGR of 43.52% in revenue from 2018 to 2024 [2][82]. - The company is transitioning towards high-quality development, with revenue expected to return to high growth and significant profit elasticity in the future [2][82]. Product Offering - The main products include drug molecular building blocks, which can be subdivided into heterocyclic compounds, aromatic compounds, and aliphatic compounds, as well as scientific reagents essential for new drug development [2][6][7]. - The company currently has 128,000 types of stock products, capable of providing over 500,000 novel and multifunctional drug molecular building blocks to meet the high-tech, multi-category, small dosage, and frequent demand from downstream clients [2][6]. Competitive Landscape - The global market for drug molecular building blocks is estimated to reach $21.8 billion in 2024, primarily dominated by foreign companies. Domestic companies, while competitive in niche areas, still lag significantly in overall scale and market share compared to international giants [2][77][80]. - Bidder Pharmaceutical's pricing for some common reagents is only 1/5 to 1/10 of that of international leader Sigma-Aldrich, with purity indicators meeting international advanced levels, positioning the company favorably in the context of accelerating domestic substitution [2][90].

| 回购方案首次披露日 | 2025/2/8 | | | | | | | --- | --- | --- | --- | --- | --- | --- | | 回购方案实施期限 | 2025 年 2 月 8 | 24 | 日~2025 | 年 | 月 | 23 日 | | 预计回购金额 | 5,000万元~10,000万元 | | | | | | | 回购用途 | □减少注册资本 √用于员工持股计划或股权激励 | | | | | | | | □用于转换公司可转债 | | | | | | | | □为维护公司价值及股东权益 | | | | | | | 累计已回购股数 | 1,668,508股 | | | | | | | 累计已回购股数占总股本比例 | 1.84% | | | | | | | 累计已回购金额 | 75,802,230.68元 | | | | | | | 实际回购价格区间 | 37.47元/股~53.30元/股 | | | | | | 证券代码：688073 证券简称：毕得医药 公告编号：2025-055 上海毕得医药科技股份有限公司 关于股份回购进展公告 本公司董事会及全体董事保证本公告内容不存 ...

Core Insights - The recent developments in the restaurant industry indicate a potential increase in IPO activity, with companies like Hu Shang A Yi and Green Tea Group moving towards public listings, suggesting a competitive landscape ahead for 2025 [1] - Despite the IPO enthusiasm, the financial performance of many listed restaurant companies has been disappointing, with over half reporting a decline in net profits for 2024 [1][2] - Notably, companies like Nayuki and Xiaobawang have faced significant losses, with Nayuki's net profit plummeting from a profit of 0.21 billion in 2023 to a loss of 9.19 billion in 2024, marking its largest loss since going public [1][2] Industry Performance - The restaurant IPO market has seen a surge, with brands like Lao Xiang Ji and Yu Jian Xiao Mian also preparing for listings, indicating a robust interest in capital markets [1] - However, the overall financial health of the industry is concerning, as a report on 20 listed restaurant companies revealed that more than half experienced a decline in net profits, with six companies reporting losses exceeding 100% [1] - Specific companies like Wei Qian (China) and Helen's have also reported significant losses, with Wei Qian's net loss reaching 0.2 billion, a 111.17% decline year-on-year [2] Company Strategies - In response to the challenging market conditions, many restaurant companies are adjusting their expansion strategies, slowing down new store openings, and closing underperforming locations [6] - For instance, Jiao Bu Jiao has reduced its new store openings to 150 in 2024, closing 69 stores, resulting in a net increase of only 81 stores, significantly lower than the previous year's 170 [6] - Similarly, Jiao Bu Jiao closed 138 stores while opening only 65, leading to a reduction in total stores from 833 to 760 [6] Market Challenges - The restaurant industry is facing challenges such as shrinking consumer demand and oversupply, leading to increased competition and price wars [4] - Companies like Jiao Bu Jiao have attempted to adjust their pricing strategies, but these efforts have not resulted in sustained growth, as evidenced by a 23.3% decline in same-store sales despite a reduction in menu prices [4] - The tea beverage segment is also experiencing difficulties, with brands like Gu Ming and Cha Bai Dao seeing significant reductions in new store openings and increased closures, indicating a cautious approach from franchisees [7]

Summary of Key Points from Conference Call Records Industry/Company Overview - **Xiaomi**: Launched the MiMo inference model with only 7 billion parameters, surpassing OpenAI's o1-mini and Alibaba's Qwen-32B-Preview, indicating a trend towards lightweight AI models for edge computing [1][8] - **North American Cloud Service Providers (CSPs)**: Major tech giants reported better-than-expected revenue and net profit despite macroeconomic uncertainties due to tariff policies [2] - **Pharmaceutical Industry**: Companies like Bidder Pharma are transitioning towards high-quality development, with increasing domestic demand for alternatives to international products [2] - **Automotive Supply Chain in Mexico**: Benefiting from tariff exemptions, companies are enhancing local production capabilities to mitigate trade risks [2] Core Insights and Arguments - **Xiaomi's AI Model**: The lightweight design of the MiMo model is expected to drive explosive demand for AI at the edge, with a consensus on the need for enhanced edge computing capabilities [1][9] - **CSP Financial Performance**: Despite expectations of weaker performance, CSPs demonstrated strong capital expenditure (Capex) reflecting robust demand for AI infrastructure [2] - **Pharmaceutical Market Dynamics**: Bidder Pharma's pricing strategy positions it competitively against international leaders, with projected net profits increasing significantly over the next few years [2] - **Automotive Supply Chain Strategy**: The establishment of production bases in Mexico is seen as a strategic move to strengthen cost advantages and localize supply chains [2] Additional Important Content - **Market Calendar Effects**: Historical analysis indicates that the A-share market typically performs better in May compared to April and June, with a rebound expected in July following a dip in June [3][5][7] - **Sector Performance**: In the context of A-share performance, sectors such as food and beverage, pharmaceuticals, electronics, and computers have shown positive returns in May [7] - **AI Hardware Trends**: The trend towards edge AI models is supported by advancements in System on Chip (SoC) technology, which is expected to significantly enhance AI processing capabilities [9][10] Conclusion The records highlight significant developments in the AI, pharmaceutical, and automotive sectors, with companies adapting to market demands and leveraging technological advancements to enhance their competitive positions. The analysis of market trends and sector performance provides valuable insights for potential investment opportunities.

Investment Rating - The report maintains a "Buy" rating for the company with a target price of 48.11 CNY, compared to the current price of 40.95 CNY [4][12]. Core Insights - The company is positioned as a leader in the domestic market for drug molecular building blocks, emphasizing a multi-dimensional approach to high-quality development, with signs of an inflection point in performance [2][16]. - The report highlights the company's continuous expansion of product varieties and quantities, significant R&D investments, and a growing international presence, which collectively contribute to its competitive edge [10][11]. Financial Summary - Projected total revenue (in million CNY) for 2024A to 2027E is as follows: 1,102 (2024A), 1,337 (2025E), 1,604 (2026E), and 1,909 (2027E), with year-on-year growth rates of 0.9%, 21.4%, 20.0%, and 19.0% respectively [3]. - Projected net profit attributable to shareholders (in million CNY) for the same period is: 117 (2024A), 146 (2025E), 179 (2026E), and 214 (2027E), with growth rates of 7.2%, 24.1%, 22.9%, and 19.6% respectively [3]. - Earnings per share (EPS) are projected to be 1.29 CNY (2024A), 1.60 CNY (2025E), 1.97 CNY (2026E), and 2.36 CNY (2027E) [3]. Company Overview - The company, established in 2007, provides professional and efficient drug molecular building blocks and scientific reagent products and services for new drug research and development [16][17]. - It has a robust product portfolio with over 128,000 types of stock items and the capability to offer more than 500,000 unique and functional drug molecular building blocks [17][21]. Industry Context - The domestic market is experiencing a recovery in demand, with a pressing need for domestic alternatives due to rising import costs and increased investment in local research and development [10][56]. - The overseas market is also showing signs of recovery, with an increase in demand from international pharmaceutical companies and contract research organizations (CROs) [10][56].

国泰海通证券股份有限公司 关于上海毕得医药科技股份有限公司 2024 年度持续督导工作现场检查报告 上海证券交易所： 国泰海通证券股份有限公司（以下简称"国泰海通"、"保荐人"）作为上海 毕得医药科技股份有限公司（以下简称"毕得医药"或"公司"）首次公开发行 股票并在科创板上市的保荐人，根据《中华人民共和国公司法》《中华人民共和 国证券法》《证券发行上市保荐业务管理办法》《上海证券交易所科创板股票上市 规则》（以下简称"《上市规则》"）和《上海证券交易所上市公司自律监管指引第 11 号——持续督导》等有关法律法规的规定，对公司 2024 年度（以下简称"本 持续督导期间"）的规范运作情况进行了现场检查，现就现场检查的有关情况报 告如下： 一、本次现场检查的基本情况 （一）保荐人 国泰海通证券股份有限公司 （二）保荐代表人 雷浩、李华东 （三）现场检查时间 2025 年 4 月 21 日至 2025 年 4 月 24 日 （四）现场检查人员 雷浩、张伯尧、汪沛 （五）现场检查内容 现场检查人员对本持续督导期内发行人公司治理及内部控制、信息披露、独 立性、与关联方的资金往来、募集资金使用情况、关联交易、对外担保、 ...

国泰海通证券股份有限公司 关于上海毕得医药科技股份有限公司 2 2024 年度持续督导年度跟踪报告 | 保荐机构名称：国泰海通证券股份有限公司 | 被保荐公司简称：毕得医药 | | --- | --- | | 保荐代表人姓名：雷浩、李华东 | 被保荐公司代码：688073.SH | 重大事项提示 经中国证券监督管理委员会《关于同意上海毕得医药科技股份有限公司首次 公开发行股票注册的批复》（证监许可[2022]1885 号）批复，上海毕得医药科技 股份有限公司（以下简称"上市公司"、"公司"或"发行人"）首次公开发行股票 1,622.9100 万股，每股面值人民币 1 元，每股发行价格人民币 88.00 元，募集资 金总额为人民币 142,816.08 万元，扣除发行费用后，实际募集资金净额为人民币 130,899.89 万元。本次发行证券已于 2022 年 10 月 11 日在上海证券交易所上市。 国泰海通证券股份有限公司（以下简称"保荐机构"或"国泰海通"）担任其持续督 导保荐机构，持续督导期间为 2022 年 10 月 11 日至 2025 年 12 月 31 日。 在 2024 年 1 月 1 日至 2 ...

上海毕得医药科技股份有限公司 2024 年年度股东大会会议资料 证券代码：688073 证券简称：毕得医药 上海毕得医药科技股份有限公司 2024 年年度股东大会会议资料 2025 年 5 月 | | | 上海毕得医药科技股份有限公司 2024 年年度股东大会会议资料 上海毕得医药科技股份有限公司 2024 年年度股东大会会议须知 为了维护全体股东的合法权益，确保股东大会的正常秩序和议事效率，保证 大会的顺利进行，根据《中华人民共和国公司法》（以下简称"《公司法》"） 《中华人民共和国证券法》（以下简称"《证券法》"）《上市公司股东会规则》 以及《上海毕得医药科技股份有限公司章程》（以下简称"《公司章程》"）等 相关规定，上海毕得医药科技股份有限公司（以下简称"公司"或"毕得医药"） 特制定股东大会会议须知： 一、为确认出席大会的股东或其代理人或其他出席者的出席资格，会议工作 人员将对出席会议者的身份进行必要的核对工作，请被核对者给予配合。 二、为保证本次大会的严肃性和正常秩序，切实维护股东的合法权益，请出 席大会的股东或其代理人或其他出席者至少提前 60 分钟到达会场签到确认参会 资格。在会议主持人宣布现场 ...

Core Insights - Bid Medicine (688073.SH) reported a revenue of 1.102 billion yuan for 2024, a year-on-year increase of 0.93%, and a net profit of 117 million yuan, up 7.17% year-on-year [1] - In Q1 2025, the company continued its steady performance with a revenue of 296 million yuan, and a net profit growth of 17.71% year-on-year, with adjusted net profit excluding share-based payments increasing by 43.29% [1] - The company is positioned as a leading player in the global molecular building blocks industry, focusing on digital upgrades and process optimization to enhance management efficiency and profitability [1][2] Business Performance - The molecular building blocks segment generated 936 million yuan in revenue, maintaining stable market share, while the scientific reagents segment saw a 13.35% year-on-year growth, reaching 166 million yuan [3] - The company has nearly 130,000 types of products, including 117,000 types of molecular building blocks, significantly exceeding industry averages [3] - R&D achievements have increased, with 41 patent applications, a 156% year-on-year rise, and a 56% increase in delivered orders [3] Market Trends - The global biopharmaceutical investment landscape has improved, with the CXO industry entering an upward cycle due to supply-demand balance [2] - The ongoing U.S.-China pharmaceutical tariff disputes have shifted towards "precise technology blockades," accelerating the trend of import substitution [2] - The global market for molecular building blocks is projected to reach 54.6 billion USD by 2026, presenting significant growth opportunities for the company [3] Global Strategy - The company achieved overseas revenue of 616 million yuan in 2024, a 10.58% increase, accounting for approximately 55.9% of total revenue [4] - Bid Medicine has established regional centers in the U.S., Germany, and India to enhance local service efficiency and customer response [4] - The company aims to strengthen its global presence through localized teams and resource integration, aspiring to become a leading supplier in the molecular building blocks sector [4][5]