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《世界肥胖地图2025》正式发布!
GLP1减重宝典· 2025-05-29 02:14
Global Obesity Trends - The report indicates that since 2000, the global issue of obesity and overweight has been worsening, with the proportion of overweight and obese adults expected to rise from 36% in 2000 to 50% by 2030, equating to nearly 3 billion adults suffering from high BMI [6] - The increase in obesity is not limited to adults; childhood and adolescent obesity rates are also rising, with about one-third of adults and 81% of adolescents failing to meet WHO's recommended physical activity standards [6] Regional Obesity Trends - In Africa, the number of overweight and obese adults is projected to increase from 107 million in 2010 to 263 million by 2030, with a notable rise in female obesity rates [7] - In the Americas, the obesity rate in the US and Canada is expected to reach 594 million adults by 2030 [7] - In Europe, despite some countries stabilizing their obesity rates, the total number of overweight and obese adults is expected to reach 429 million by 2030 [7] - Southeast Asia, particularly India and Indonesia, is projected to have 619 million overweight and obese adults by 2030 [7] - In the Western Pacific, including China and Japan, the number of overweight and obese adults is expected to reach 662 million by 2030 [7] Obesity and Non-Communicable Diseases (NCD) - Obesity is a significant risk factor for various NCDs, including type 2 diabetes, cardiovascular diseases, cancers, and chronic respiratory diseases, with approximately 16 million adults dying prematurely from obesity-related NCDs in 2021, accounting for 15% of all NCD-related premature deaths [8][9] Global Health System Preparedness - The report highlights that most countries' healthcare systems are not adequately prepared to handle the dual pressures of obesity and NCDs, lacking systematic obesity management guidelines and effective public health policies [10] - Many countries have not implemented effective preventive measures, such as taxing unhealthy foods and limiting unhealthy food advertising, which are crucial for reducing obesity rates [10] National Policy Progress - Some countries, like Mexico, India, and Brazil, have begun implementing specific measures to combat obesity, such as sugary drink taxes and food labeling regulations [11] - However, 126 countries have yet to introduce any obesity-related policies, particularly in low- and middle-income countries [11] China's Obesity Characteristics - China's adult high BMI prevalence is expected to continue rising, with approximately 41% of adults projected to have high BMI by 2025, and 9% classified as obese [12] - By 2030, the total number of adults with high BMI in China is expected to reach 515 million, with significant gender differences in high BMI prevalence [16] Health Risks Associated with High BMI in China - High BMI is a major risk factor for type 2 diabetes, with about 40% of premature deaths from diabetes in China linked to high BMI [17] - High BMI significantly increases the risk of cardiovascular diseases, with approximately 15% of premature cardiovascular deaths attributed to high BMI in 2021 [17] - High BMI is also associated with various cancers, with around 16% of cancer-related premature deaths in China linked to high BMI [17] Policy and Action Recommendations - The report calls for immediate action from governments, international organizations, and society to address the growing obesity crisis, proposing science-based policy recommendations [21] - Recommendations include creating healthy living environments, enhancing public awareness and education on healthy diets and physical activity, and transforming health systems to better manage obesity and related chronic diseases [21]
一个让你怎么都瘦不下来的原因,很多人都不知道
Yang Shi Xin Wen· 2025-05-25 01:26
Core Concept - Insulin resistance is a growing concern, often linked to difficulties in weight loss and metabolic health issues, affecting many individuals who struggle with weight management [1][28]. Group 1: Understanding Insulin Resistance - Insulin is a hormone secreted by the pancreas that regulates blood sugar levels by facilitating the uptake of glucose into cells for energy [3][5]. - Insulin resistance occurs when the body's sensitivity to insulin decreases, requiring more insulin to achieve the same effect, which can lead to pancreatic fatigue and potentially diabetes [5][6]. Group 2: Causes of Insulin Resistance - Genetic factors play a significant role, with individuals having a family history of diabetes being more susceptible [6]. - Age is another critical factor, as metabolic functions decline with age, increasing the risk of insulin resistance [6]. - Environmental and lifestyle factors, such as obesity, sedentary behavior, unhealthy diets, and certain medications, also contribute to the development of insulin resistance [8][10][11][13]. Group 3: Symptoms and Assessment - Insulin resistance often lacks specific symptoms but is commonly associated with obesity and abnormal blood sugar levels [15]. - Clinical assessments for insulin resistance include measuring fasting insulin levels and using various anthropometric indicators [16][17][19]. Group 4: Health Implications - Insulin resistance can lead to several health issues, including diabetes, obesity, cardiovascular diseases, and fatty liver disease [20][21][22][23]. - There is also emerging evidence linking insulin resistance to chronic conditions such as Alzheimer's disease and certain cancers, although further research is needed [24]. Group 5: Management Strategies - Adopting healthy dietary habits, such as reducing refined carbohydrates and unhealthy fats while increasing protein intake, can help manage insulin resistance [25][26]. - Regular physical activity is essential, as it enhances muscle mass and improves glucose utilization, with recommendations for at least 150 minutes of moderate-intensity exercise weekly [26]. - Medical intervention may be necessary for individuals showing prediabetic symptoms, emphasizing the importance of lifestyle changes alongside medication [28].
国家喊你减肥实际上是在为你省大钱!
GLP1减重宝典· 2025-05-21 04:03
2025年5月17日至23日是第十一届全民营养周,今年的主题定为:"吃动平衡 健康体重 全民行动"。今年还将继续推进"体重管理年"专项行动, 进一步推广健康的生活方式。"国家喊你减肥"这一话题早已深入人心,凸显了我国肥胖问题的严重性。 国家卫生健康委面向社会发布的《体重管理指导原则(2024年版)》提到,有研究预测,如果不加以有效控制,到2030年我国成人超重和肥胖 率将高达70.5%,儿童超重和肥胖率也将达到31.8%。 许多人仍然认为肥胖只是"外形不美观",但实际上,肥胖是一种隐匿的代谢危机。它不仅危害身体健康,还会带来经济负担、时间损耗,甚至 增加机会成本。 的肥胖率上升了1.8%,女孩则略有下降。研究还指出, 肥胖的儿童在成年后大多仍然肥胖,相关慢性疾病也呈现出年轻化的趋势 。 肥胖从来不是一个"单一的指标",而是众多疾病的起点。只要BMI超过正常范围,高血压、糖尿病、脂肪肝、肿瘤等慢性病便会如多米诺骨牌 般接踵而至。这些健康问题不仅严重损害生活质量,更会直接影响健康寿命的长短。 ▍肥胖其实是"富贵病" 许多人把肥胖调侃为"富贵病",觉得不过是"吃得好"带来的身材变化,甚至认为"胖点没什么大碍"。可当 ...
体重轻一点 烦恼少一点 保持“吃动平衡”好处有这些
Yang Shi Xin Wen· 2025-05-18 01:30
Group 1 - The theme of the 11th National Nutrition Week is "Balanced Eating and Exercise for Healthy Weight: A National Action" [1] - The National Health Commission predicts that by 2030, the adult overweight and obesity rate in China will reach 70.5%, and the rate for children will reach 31.8% [1] - Obesity is recognized as a chronic, recurrent metabolic disease that disrupts metabolic balance and damages multiple systems, including cardiovascular and endocrine systems [2][4] Group 2 - Obesity is a major driver of chronic diseases in China, with 34.8% of adults classified as overweight and 14.1% as obese [4] - Among obese individuals, 22.8% have three or more metabolic-related diseases, significantly higher than the 3.0% in normal-weight individuals [4] - Obesity is linked to various chronic diseases such as hypertension, diabetes, and fatty liver, which can reduce quality of life and lifespan [6] Group 3 - Overweight and obese individuals utilize medical services more frequently than those of normal weight, particularly in outpatient and examination settings [7] - The "time cost" of obesity affects both adults and children, with obese children showing lower self-esteem and reduced physical abilities, impacting their social and academic performance [9] - A weight loss of 5% to 10% can significantly reduce the risk of diseases like diabetes and hypertension [10] Group 4 - Improvements in health often do not require expensive medications or extreme surgeries but can be achieved through regular diet, moderate exercise, and early intervention [12]
Nature重磅发现:牛磺酸竟能帮助癌细胞代谢,促进白血病
生物世界· 2025-05-15 09:39
Core Viewpoint - Recent studies reveal that taurine, a common ingredient in energy drinks, plays a significant role in leukemia progression by driving glycolysis in the tumor microenvironment, suggesting caution in its supplementation for leukemia patients [2][9]. Group 1: Taurine's Role in Leukemia - A study from the University of Rochester indicates that taurine from the tumor niche promotes glycolysis, facilitating leukemia development [2]. - The research utilized single-cell RNA sequencing to identify molecular interactions between the bone marrow microenvironment and leukemia stem cells (LSC), highlighting the importance of these interactions in leukemia progression [5]. - Taurine biosynthesis driven by cysteine dioxygenase-1 (CDO1) is limited to osteoblast lineage cells and increases during myeloid disease progression, with LSC relying on taurine transport proteins for their growth [5][6]. Group 2: Implications for Treatment - Inhibition of taurine transport proteins significantly suppresses the progression of acute myeloid leukemia (AML) in mouse models and human patient-derived cells [6]. - Elevated expression of taurine transport proteins in venetoclax-resistant AML patients suggests a potential therapeutic target, as inhibiting these proteins can enhance the efficacy of existing treatments [6]. - The study indicates that taurine uptake deficiency reduces leukemia stem cell capabilities by inhibiting mTOR activation and downstream glycolysis [6]. Group 3: Broader Research Context - Other studies have linked taurine deficiency to aging and its potential to extend healthspan in various organisms, indicating its multifaceted role in health and disease [9][11]. - Research has shown that taurine supplementation can reactivate exhausted CD8+ T cells, enhancing cancer treatment outcomes, further complicating the narrative around taurine's role in cancer [11]. - The discovery of a novel N-acetyltaurine hydrolase (PTER) suggests new avenues for obesity treatment, indicating taurine's relevance beyond oncology [14].
中国胖子,即将反超美国
虎嗅APP· 2025-04-01 14:18
Core Viewpoint - The article discusses the alarming rise in obesity rates in China, predicting that by 2030, the adult overweight and obesity rate could reach 70.5%, approaching levels seen in developed countries like the United States [7][18]. Group 1: Obesity Trends in China - Over the past two decades, the percentage of overweight or obese adults in China has increased from 20% in 2000 to 41% in 2023 [4]. - The National Health Commission cites research predicting that if current trends continue, the adult obesity rate in China could reach 70.5% by 2030 [7][18]. - The article highlights that while China's obesity rates are rising, they still lag behind those of developed countries, where the rates are generally higher [6][8]. Group 2: Impact of Ultra-Processed Foods - The consumption of ultra-processed foods is linked to the rising obesity rates, with a 10% increase in their caloric contribution correlating to a 7% increase in the risk of becoming overweight [11]. - From 1990 to 2019, the caloric contribution of industrially processed foods in China rose from 1.5% to 28.7%, indicating a significant increase in the consumption of ultra-processed foods [12]. - In developed countries, ultra-processed foods account for a substantial portion of daily caloric intake, with the U.S., U.K., and Canada reporting figures of 57.9%, 56.8%, and 45.1% respectively [12]. Group 3: Nutritional Recommendations - To combat obesity, the article emphasizes the importance of reducing ultra-processed food intake and increasing the consumption of natural and minimally processed foods [21][38]. - The National Health Commission has launched a "Weight Management Year" initiative, promoting dietary guidelines that prioritize balanced nutrition while considering regional dietary preferences [34][35]. - The guidelines recommend increasing the intake of dairy products and vegetables, which are high in protein, calcium, and dietary fiber, to help manage weight effectively [39].