Group 1 - WuXi AppTec, a leading player in the CXO sector, reported better-than-expected performance with double-digit growth in both revenue and net profit, maintaining a revenue guidance of RMB 41.5 billion to RMB 43 billion for 2025 [1] - In 2024, WuXi AppTec generated RMB 16.64 billion from the top 20 global pharmaceutical companies, highlighting its significant role in the global CXO market [1] - The Hong Kong innovation drug index saw a significant drop in P/E ratio from 64 times on February 21 to 27 times on April 28, indicating a strong value proposition for investors [1] Group 2 - The innovation drug ETF (159992) tracks an index that includes leading companies in the innovation drug industry, benefiting from trends such as AI-enabled drug development and the international expansion of domestic innovative drugs [2] - According to Insight database, there were 79 new drug license-out transactions in 2024, with 24 transactions completed in the first five months of 2025, totaling over USD 2 billion, showcasing the growing international recognition of Chinese innovative drugs [2] - Chinese pharmaceutical companies are demonstrating strong competitiveness in the global market through high-standard R&D, particularly in areas like antibodies and ADCs [2]

Core Viewpoint - The company reported a significant decline in performance for 2024, with a revenue of 2.467 billion yuan, down 5.48% year-on-year, and a net loss of 299 million yuan, marking a drastic shift from a profit of 263 million yuan in the previous year [1][4][10] Revenue and Profitability - The company's revenue has been on a downward trend since 2022, with figures of 2.676 billion yuan in 2022, 2.611 billion yuan in 2023, and 2.467 billion yuan in 2024 [2] - The traditional Chinese medicine segment generated 1.318 billion yuan, accounting for 53.93% of total revenue, while chemical drugs contributed 899 million yuan, or 36.81% [2] - The average price of the core product, Compound XueShuanTong series, dropped by 52% after entering national procurement, leading to a revenue decrease of approximately 120 million yuan despite an 18% increase in sales volume [3] Business Segments - The company is undergoing a transformation from traditional Chinese medicine to an innovative pharmaceutical company, focusing on three main business areas: traditional Chinese medicine, chemical drugs, and innovative drugs [1][10] - The chemical generic drug sector is being refined, with six products approved in 2024, while the raw materials and intermediates segment saw a revenue drop of 26.98% to 30.49 million yuan [3][5] R&D and Innovation - The company has a strong commitment to R&D, with a research expense ratio of 10.68% in 2024, despite a decrease from 12.5% in 2023 [8] - The company has halted several clinical projects, resulting in a one-time impairment loss of 207 million yuan, reflecting a focus on core pipelines [8][9] - The innovative drug RAY1225 is projected to generate significant sales in the diabetes and obesity management market, with estimated contributions of 1.369 billion yuan for diabetes and 700 million yuan for weight management by 2033 [9] Asset Management and Impairment - The company recorded an asset impairment loss of 547 million yuan in 2024, primarily due to goodwill impairment related to subsidiaries and R&D projects [6][7] - The goodwill value at the end of 2024 was 318 million yuan, significantly reduced from 530 million yuan in 2023, indicating challenges in integrating acquired assets [6][7] Market Position and Future Outlook - The company is positioned in a critical transition phase, aiming to redefine its industry status and enhance its innovative capabilities [1][10] - The next 2-3 years are crucial for the company to validate its innovative drug commercialization capabilities, with potential risks if core projects face obstacles [10]

Core Viewpoint - The focus of institutional investors on Yipinhong's innovative drug AR882 highlights its potential in the gout treatment market, with significant clinical trial progress and FDA fast track designation [1][2][3]. Group 1: Clinical Trial Progress - Yipinhong's AR882 has received FDA fast track designation for treating visible tophi in gout patients, indicating a potential gap in the oral medication market for this condition [2]. - The Phase III clinical trials for AR882 have commenced, with the first patient enrolled on March 4, 2025, and the global REDUCE2 trial completing patient enrollment shortly thereafter [2]. - The REDUCE1 trial, parallel to REDUCE2, also began patient enrollment on March 17, 2025, focusing on the drug's efficacy in lowering serum uric acid levels [2]. Group 2: Competitive Landscape - Current treatments for hyperuricemia and gout are limited, with existing drugs primarily focused on disease prevention and pain management, while AR882 aims to provide a more effective solution [3]. - Yipinhong asserts that AR882's clinical data shows it can not only lower serum uric acid but also dissolve gout tophi, setting it apart from competitors that only demonstrate uric acid reduction [3]. Group 3: Drug Development and Safety - AR882's molecular design aims to reduce liver toxicity and enhance efficacy, with a prolonged action time of up to 24 hours, addressing safety concerns associated with existing treatments [4]. - The company is optimistic about AR882's market potential, given its unique clinical data and the significant demand in the gout treatment market [4]. Group 4: Research and Development Pipeline - Yipinhong has a total of 71 projects in development, including 15 innovative drug projects, with AR882 and another drug, APH01727, currently in clinical trials [5]. - The company is building a smart manufacturing base compliant with FDA and EU standards, integrating advanced automation and information management systems to support global drug manufacturing needs [5]. Group 5: Subsidiary Developments - Yipinhong's subsidiary, Fendi Pharmaceutical, is focused on developing targeted protein degradation agents for cancer and viral infections, utilizing advanced technologies to enhance drug discovery [6]. - Another subsidiary, Alpha Molecular, is leveraging AI and original biocomputing for drug research targeting GPCRs, with several self-developed pipelines nearing clinical application [6].

4月28日，凯因科技(688687)披露2024年年度报告和2025年一季报。公司2024年度实现营业收入12.30亿 元，归母净利润1.42亿元，同比增长22.18%；2025年一季度实现营收2.32亿元，同比增长8.90%，归母 净利润2566.85万元，同比增长15.92%。公司维持较高研发投入强度，2024年研发投入1.57亿元，占营 业收入比例为12.79%，同比增加0.57个百分点。核心项目取得突破性进展 报告期内，公司多个研发项目取得突破性进展：KW-001(培集成干扰素α-2注射液乙肝适应症)完成Ⅲ期 临床试验并提交药品注册上市许可申请；KW-045(人干扰素α2b喷雾剂)针对儿童疱疹性咽峡炎适应症 Ⅱa期临床试验全部受试者完成治疗及随访；KW-051(培集成干扰素α-2注射液带状疱疹适应症)Ⅱ期临床 试验全部受试者完成治疗及随访；KW-053人干扰素α2b阴道泡腾片辅助治疗尖锐湿疣适应症取得药物临 床试验批准通知书，Ⅱ期试验推进中；GL-004(马来酸阿伐曲泊帕片)取得药品注册证书。 公司于2024年共申请发明专利9项，获得发明专利授权7项；至报告期末，累计申请发明专利175项，累 计获得发 ...

证券代码：301263 证券简称：泰恩康 广东泰恩康医药股份有限公司投资者关系活动记录表 编号：投-002 | | √ 特定对象调研 □ 分析师会议 | | --- | --- | | 投资者关系活动 | □ 媒体采访 □ 业绩说明会 | | 类别 | □ 新闻发布会 □ 路演活动 | | | □ 现场参观 | | | □ 其他 宝盈基金管理有限公司、浙江浙商证券资产管理有限公司、上海 | | | 保银投资管理有限公司、鹏华基金管理有限公司、华夏基金管理 | | | 有限公司、深圳正圆投资有限公司、上海鑫垣私募基金管理有限 | | | 公司、交银施罗德基金管理有限公司、前海人寿保险股份有限公 | | | 司、东证资管、卓瑜资本、东吴证券、上海五地私募基金管理有 | | 参与单位名称及 | 限公司、光大保德信基金管理有限公司、中海基金管理有限公司 | | 人员姓名 | 、东方香港销售、华安证券、国泰海通证券、方正医药、卓瑜资 | | | 本、天风证券、优益增、西部证券、智合远见私募基金、华福证 | | | 券、森锦、中信医药、调兵投资、东方证券、申万宏源证券、招 | | | 商证券、银河证券、华创证券、华源证券 ...

证券代码：002907 证券简称：华森制药 重庆华森制药股份有限公司 投资者关系活动记录表 编号：2025-003 投资者关系活动类别 特定对象调研 分析师会议 媒体采访 业绩说明会 □新闻发布会 □路演活动 □现场参观 □其他 参与单位名称及 人员姓名 深圳市林园投资管理有限责任公司 董事长林园 上海承风金萍私募基金管理有限公司 董事长余承 成都唯赢投资咨询有限公司 投资总监汪海 等一行 时间 2025 年 4 月 27 日 、2025 年 4 月 28 日 地点 公司 2 楼会议室 上市公司接待人姓名 周智如（证券事务代表） 徐 君（证券事务专员） 刘 璐（证券事务专员） 投资者关系活动 主要内容介绍 一、公司在遵守信息披露制度的前提下，介绍公司经营业 绩、产品布局、市场开发和生产管理等情况，沟通内容与公司 公告内容一致。 二、采取问答方式，由周智如女士负责回答： 1.公司 2025 年一季度增长放缓，具体原因是什么？ 答：在 2025 年一季度，公司实现营业收入 2.39 亿元，整 体收入较上年同期增加 4.62%，收入增速放缓主要为上年同期流 感高发，患者多出现咽喉不适症状，公司权重产品甘桔冰梅片 受 ...

Core Insights - Fosun Pharma reported a revenue of 41.067 billion yuan in 2024, a slight decrease of 0.80% year-on-year, while net profit attributable to shareholders increased by 16.08% to 2.770 billion yuan [1][2] - The company achieved a net cash flow from operating activities of 4.477 billion yuan, reflecting a significant increase of 31.13% compared to the previous year, indicating improved free cash flow to support strategic transformation and R&D investments [2][3] Financial Performance - Revenue: 41.067 billion yuan in 2024, down from 41.400 billion yuan in 2023, a decrease of 0.80% [2] - Net Profit: 2.770 billion yuan in 2024, up from 2.386 billion yuan in 2023, an increase of 16.08% [1][2] - Net Profit (excluding non-recurring items): 2.314 billion yuan, a rise of 15.10% from 2.011 billion yuan in 2023 [2] - Basic Earnings per Share: 1.04 yuan [1] Business Segmentation - Pharmaceutical Revenue: 28.924 billion yuan, a decline of 4.29% year-on-year; key products like Hanquyou® (trastuzumab) saw global sales of 2.810 billion yuan, an increase of 11% [3] - Medical Devices and Diagnostics Revenue: 4.323 billion yuan, down 1.53% due to decreased demand for COVID-19 products [3] - Healthcare Services Revenue: 7.647 billion yuan, an increase of 14.61% driven by specialized construction and smart healthcare initiatives [3] R&D and Innovation - R&D Investment: 5.554 billion yuan, accounting for 13.52% of revenue; seven innovative drugs/biosimilars were approved for market [3] - Notable Approvals: Slulizumab received EU approval, and HLX14 (biosimilar to dezuizumab) is under review in the US and EU [3] - Collaboration: The company is exploring new directions in nuclear medicine and gene therapy through partnerships with industry funds [3] Shareholder Returns - Proposed Dividend: The company plans to distribute a cash dividend of 3.20 yuan per 10 shares (tax included) [3]

证券代码：300404 证券简称：博济医药 博济医药科技股份有限公司 投资者关系活动记录表 | | □特定对象调研 □分析师会议 | | --- | --- | | 投资者关系活 | □媒体采访 □业绩说明会 | | 动类别 | □新闻发布会 □路演活动 | | | □现场参观 | | | ■其他（投资者电话交流会） | | 参与单位名称 | | | | 招商证券、开源证券、华安证券、申万宏源、信达证券、光大证 券、兴业证券、东北证券、太平洋证券、华鑫证券、银河证券、 | | | 华福证券、国泰海通、华创证券、源阖投资、健顺投资、华源医 | | | 药、中信资管、磐松私募、国联民生、尚诚资产、华西医药、鸿 | | 及人员姓名 | 运私募、宜宾发展创投、九祥资产、星允投资、平安证券、中泰 | | | 证券、杭贵投资、泰山财保、香港沪光国际投资、大家资产、明 | | | 达资产、天驷资产、前海明辉、中融汇信、中航赛维 | | 时间 | 2025 年 4 月 27 日（星期日） | | 地点 | 广州 | | 上市公司接待 | 董事长、总经理：王廷春 | | 人员姓名 | 副总经理、财务总监：欧秀清 | | | 副 ...

2025 年 04 月 28 日 持续研发投入，创新转型收获在即 买入(首次) 事件 分析师：胡博新 S1050522120002 hubx@cfsc.com.cn | 基本数据 | 2025-04-25 | | --- | --- | | 当前股价（元） | 37.91 | | 总市值（亿元） | 171 | | 总股本（百万股） | 452 | | 流通股本（百万股） | 418 | | 52 周价格范围（元） | 12.9-41.97 | | 日均成交额（百万元） | 164.37 | 市场表现 资料来源：Wind，华鑫证券研究 -50 0 50 100 (%) 一品红 沪深300 相关研究 —一品红（300723.SZ）公司事件点评报告 一品红药业发布 2024 年年报及 2025 年 1 季报：2024 年实现 营收 14.50 亿元，同比下降 42.07%；实现归母净利润-5.40 亿元，2025 年 Q1 实现收入 3.77 亿元，同比下降 39.48%，实 现归母净利润 0.57 亿元，同比下降 43.70%。 券 研 究 报 告 公 司 研 究 投资要点 ▌ 集采和销售模式变化致收入和利润大 ...

持续研发投入，创新转型收获在即 资料来源：Wind，华鑫证券研究 -50 0 50 100 (%) 一品红 沪深300 相关研究 买入(首次) 事件 分析师：胡博新 S1050522120002 hubx@cfsc.com.cn 2025 年 04 月 28 日 | 基本数据 | 2025-04-25 | | --- | --- | | 当前股价（元） | 37.91 | | 总市值（亿元） | 171 | | 总股本（百万股） | 452 | | 流通股本（百万股） | 418 | | 52 周价格范围（元） | 12.9-41.97 | | 日均成交额（百万元） | 164.37 | 市场表现 —一品红（300723.SZ）公司事件点评报告 一品红药业发布 2024 年年报及 2025 年 1 季报：2024 年实现 营收 14.50 亿元，同比下降 42.07%；实现归母净利润-5.40 亿元，2025 年 Q1 实现收入 3.77 亿元，同比下降 39.48%，实 现归母净利润 0.57 亿元，同比下降 43.70%。 投资要点 ▌ 集采和销售模式变化致收入和利润大幅变化 2023 年公司对营销模式进 ...