产能陆续投产，期待模制瓶放量加速 医疗器械 力诺药包（301188.SZ） 证券研究报告/公司点评报告 2025 年 05 月 12 日 | 评级： | 买入（维持） | 公司盈利预测及估值 | | | | | | | --- | --- | --- | --- | --- | --- | --- | --- | | | | 指标 | 2023A | 2024A | 2025E | 2026E | 2027E | | 分析师：孙颖 | | 营业收入（百万元） | 947 | 1,081 | 1,364 | 1,548 | 1,727 | | | | 增长率 yoy% | 15% | 14% | 26% | 13% | 12% | | 执业证书编号：S0740519070002 | | 归母净利润（百万元） | 66 | 66 | 119 | 162 | 203 | | Email：sunying@zts.com.cn | | 增长率 yoy% | -43% | 0% | 80% | 37% | 25% | | | | 每股收益（元） | 0.28 | 0.28 | 0.51 | 0.70 | 0.87 | | ...

Core Viewpoint - As of May 8, 2025, the stock price of Puri Eye Hospital (301239) closed at 43.0 yuan, reflecting a decrease of 1.17% with a turnover rate of 2.33% and a trading volume of 16,500 shares, amounting to a transaction value of 71.48 million yuan [1]. Group 1: Business Operations - Puri Eye Hospital operates as a large-scale non-public ophthalmology specialty medical group, with all its hospitals included in the medical insurance designated point system [2]. - The company has a dual pricing logic for its products and services: it has full pricing autonomy for selective consumer projects and high-end examinations (outside the medical insurance catalog), while it strictly adheres to national medical insurance cost control policies for basic treatments and routine examinations (within the medical insurance catalog) [2]. - The company is leveraging the benefits of medical insurance cost control policies, such as centralized procurement price reductions and optimized payment methods, to enhance the accessibility and affordability of eye disease treatments for patients [2]. Group 2: Financial Flow - On May 8, 2025, the financial flow for Puri Eye Hospital showed a net outflow of 3.06 million yuan from major funds and a net outflow of 2.09 million yuan from speculative funds, while retail investors saw a net inflow of 5.15 million yuan [2].

Core Viewpoint - The company reported a significant decline in revenue and net profit for 2024, with ongoing challenges in the market impacting performance, but there are signs of potential recovery in the testing business and advancements in digital transformation [1][3][4]. Financial Performance - In 2024, the company achieved operating revenue of 7.19 billion, a year-on-year decrease of 15.81%, and a net profit attributable to shareholders of -0.38 billion, a decline of 159.26% [1] - For Q1 2025, the company reported operating revenue of 1.47 billion, down 20.35%, and a net profit of -0.03 billion, a decrease of 49.09% [1] - The fourth quarter of 2024 saw operating revenue of 1.57 billion, a decline of 29.57%, and a net profit of -0.48 billion, a drop of 805.23% [1] Cost Structure - In 2024, the sales expense ratio was 12.94%, an increase of 1.06 percentage points; the management expense ratio was 8.32%, a slight decrease of 0.05 percentage points; the R&D expense ratio was 5.57%, up by 0.10 percentage points; and the financial expense ratio was -0.04%, down by 0.03 percentage points [2] - The gross profit margin for 2024 was 33.15%, a decrease of 3.33 percentage points, primarily due to reduced revenue scale and increased fixed cost amortization [2] - The net profit margin for 2024 was -5.77%, a decline of 13.23 percentage points [2] Market and Business Outlook - The testing business is expected to gradually recover, with the company focusing on product innovation and maintaining a leading market share despite competitive pressures [3] - In 2024, the company saw a 2.94% increase in specimen testing volume, with significant revenue growth in specialized products such as tumor screening (69.7% increase) and blood cancer RNA-seq (170% increase) [3] - The company is enhancing its digital transformation efforts, utilizing AI and big data to improve laboratory efficiency by 50-90% and expanding its service platform to over 570,000 downstream clients [4] Profit Forecast and Investment Recommendation - The company adjusted its profit forecast, expecting revenues of 7.50 billion, 8.22 billion, and 9.02 billion for 2025-2027, with net profits of 0.35 billion, 0.64 billion, and 0.70 billion respectively [4] - The company is positioned to benefit from industry growth and improved laboratory profitability, maintaining a "buy" rating [4]

Investment Rating - The report rates the pharmaceutical industry as "Outperform" [1] - Sub-industry ratings include "Add" for pharmaceutical manufacturing and pharmaceutical services [1] Core Insights - The report is optimistic about innovative drugs, CXO, and strong consumer performance in Q1 2025 [5][27] - In April 2025, the pharmaceutical sector performed similarly to the market, with the SHCOMP index down 1.7% and SW Pharma Bio down 2.1%, ranking 11th among Shenwan primary industries [9][28] - The premium of the pharmaceutical sector over all A-Shares is currently at a normal level of 81.01% [18][28] Summary by Sections 1. Focus on Innovative Drugs and CXO - Key A-share stocks recommended include Jiangsu Heng Rui Medicine, Betta Pharmaceuticals, Shenzhen Salubris Pharmaceuticals, Sichuan Kelun Pharmaceutical, Remegen, Huadong Medicine, WuXi AppTec, APT Medical, and AIER EYE HOSPITAL GROUP [5][27] - H-share top picks include Wuxi Biologics Cayman, PATEO, Innovent Biologics, and Zai Lab, with beneficiaries being CSPC Pharmaceutical Group, Gushengtang, and Angelalign [27] 2. April 2025 Pharmaceutical Sector Performance - The pharmaceutical sector's performance was on par with the market, with notable sub-sectors being chemical preparations (+2.8%), pharmaceutical commerce (+1.5%), and chemical raw materials (+0.7%) [12][28] - Top gainers included Apichope Pharmaceutical (+56.2%), Qianjiang Yongan Pharmaceutical (+55.9%), and Kexing Biopharm Co., Ltd. (+55.2%), while top losers were Hainan Poly Pharm (-71.9%), Landfar Bio-Medicine Co., Ltd (-40.0%), and Jiangsu Wuzhong Industrial (-39.5%) [17][28] 3. Performance Disparities in 2024 and Q1 2025 - In 2024, the pharmaceutical sector's overall revenue fell by 1.5% YoY, and net profit decreased by 12.5% YoY, with medical consumables, chemical preparations, and blood products showing positive growth [22][28] - In Q1 2025, the sector's revenue fell by 6.1% YoY, and net profit fell by 9.7% YoY, with medical R&D outsourcing, consumables, and hospitals performing well [22][28] 4. Profitability Metrics - The gross profit margin (GPM) for the pharmaceutical sector fell by 0.5pp YoY in 2024, while the net profit margin (NPM) fell by 0.8pp YoY [24][28] - In Q1 2025, GPM decreased by 1.6pp YoY, and NPM decreased by 0.4pp YoY, with medical R&D outsourcing showing improvements in both GPM and NPM [24][28]

证券代码：000950 证券简称：重药控股 重药控股股份有限公司投资者关系活动记录表 编号：2025-004 | | □特定对象调研 □分析师会议 | | --- | --- | | 投资者关系活动类 | □媒体采访 业绩说明会 | | 别 | □新闻发布会 □路演活动 | | | □现场参观 | | | □其他（请文字说明其他活动内容） | | | 线上参与公司 年度业绩说明会的投资者 2024 上市公司接待人员： | | | 董事长 袁泉 | | 活动参与人员 | 独立董事 刘胜强 | | | 财务总监、董事会秘书 邱天 | | | 证券事务代表 赵婧 | | 时间 | 年 月 日下午 2025 5 6 15:00-16:00 | | 地点 | 价值在线（www.ir-online.cn） | | 形式 | 网络互动方式 | | | 1、重药控股如何促进提高国有资产的保值增值，切实回报 | | | 投资者。 重药控股上市有 年多了，股价长时间低于净资产值， 6 | | | 至今股价也低于 2017 年重药上市时的配售发行价（5.93 元/股）， | | | 令战略投资者和普通投资者在 年多时间里，长期处 ...

Core Viewpoint - The pharmaceutical industry in China is undergoing significant policy changes, impacting the market landscape, with Fu'an Pharmaceutical demonstrating strong performance amidst these challenges, achieving a revenue of 2.391 billion yuan and a net profit of 280 million yuan in 2024, reflecting a year-on-year growth of 20.69% [1] Group 1: Company Overview - Fu'an Pharmaceutical, established in 2004 and listed in 2011, specializes in antibiotics and has built a strong competitive moat in the generic drug sector over 20 years [2] - The company has a comprehensive chemical pharmaceutical supply chain, covering drug research and development, intermediates, raw materials, and production, which positions it favorably in the changing industry landscape [2][3] Group 2: Product and R&D Competitiveness - Fu'an focuses on its core business, accumulating technical advantages and operational experience, leading to a diverse product range across various therapeutic areas [3] - The company has a stable sales team and network, actively participating in national procurement, with 13 products selected by the end of 2024, positively impacting overall performance [3][4] - R&D is a core competitive advantage, with a dedicated team responsible for various stages of drug development, and the R&D expense ratio has increased from 3.67% in 2020 to 6.41% in 2024, enhancing competitive positioning [4] Group 3: Financial Performance - Despite industry-wide revenue and profit fluctuations due to policy changes, Fu'an's revenue reached 2.391 billion yuan in 2024, only a slight decline of 9.68% [5] - The company maintained a high gross margin of 52.96% in 2024, with a significant reduction in sales expenses from 45.06% in 2020 to 23.56% in 2024, contributing to a net profit increase of 20.69% to 280 million yuan [6] - The net profit margin improved from 8.76% in 2023 to 11.7% in 2024, with a remarkable growth in non-recurring net profit by 14.68 times to 259 million yuan [6] Group 4: Market Dynamics and Future Outlook - The pharmaceutical manufacturing industry in China is expected to grow due to an aging population and increasing health awareness, with high-value products becoming key growth drivers [7] - Recent policy changes, including the implementation of the National Drug Standard Management Measures, are set to enhance drug quality and safety, benefiting companies like Fu'an that can adapt and innovate [7][8] - Fu'an has successfully participated in national procurement, with three products winning bids, while also expanding its market presence for non-procurement products to mitigate pricing pressures [9] Group 5: Strategic Development - Fu'an's approach to continuous improvement and innovation positions it well in a competitive market, demonstrating that opportunities for value re-evaluation exist even in mature sectors [10]

Financial Performance - In 2024, the company achieved operating revenue of CNY 4.027 billion, a year-on-year increase of 0.35% [2] - The net profit attributable to shareholders was CNY 429 million, a decrease of 35.63% [2] - As of the end of the reporting period, total assets amounted to CNY 7.924 billion, with net assets of CNY 5.794 billion [3] - In Q1 2025, operating revenue reached CNY 1.093 billion, a year-on-year growth of 11.74%, while net profit was CNY 150 million, down 4.00% [3] Business Segment Performance - In 2024, the cataract business generated revenue of CNY 873 million, a decline of 11.56% due to the implementation of centralized procurement policies [3] - The refractive business achieved revenue of CNY 1.296 billion, growing by 7.44% [3] - The comprehensive optometry business reported revenue of CNY 1.069 billion, an increase of 5.15% [3] - The eye posterior segment business saw revenue of CNY 536 million, a slight increase of 0.19% [3] Market Outlook - The aging population is expected to drive demand for various age-related eye diseases, including cataracts, with an estimated 80% incidence rate among individuals over 60 [8] - By 2050, the number of cataract patients in China is projected to reach 241 million [8] - The prevalence of myopia among children and adolescents is a significant public health issue, with a reported rate of 51.9% in 2022 [9] - The market for eye care services in China is anticipated to grow, driven by increasing demand in various segments [9] Strategic Initiatives - The company plans to expand its operations through mergers and acquisitions or self-built facilities in 24 key investment provinces [10] - There is a focus on enhancing the eye care service network and improving operational efficiency through technology and management systems [7] - The company is actively seeking overseas expansion opportunities, particularly in Europe and Asia, to enhance its global footprint [11]

Core Viewpoint - Duorui Pharmaceutical (301075.SZ) reported its first annual loss since going public, with total revenue of 241 million yuan, a year-on-year decline of 28.02%, and a net profit attributable to shareholders of -62.67 million yuan, marking a staggering decline of 432.44% from profit to loss [2] Group 1: Financial Performance - The company's core product, sodium acetate Ringer's injection, which previously accounted for over 90% of revenue, saw sales plummet from 465 million yuan in 2021 to less than 120 million yuan in 2024, a nearly 50% year-on-year decline [3] - The decline in sales was primarily due to the product being selected in the 10th batch of national drug procurement, resulting in a significant drop in the bidding price [3] - Operating cash flow for 2024 was -67.18 million yuan, a drastic decrease of 641.19% year-on-year, mainly due to reduced sales revenue [6] Group 2: Strategic Challenges - The company is heavily reliant on a single core product, which exposes it to risks in a changing policy environment characterized by medical insurance cost control and normalized bulk procurement [3] - Duorui Pharmaceutical's acquisition of a 70% stake in Shanghai Jianling for 271 million yuan, which included debt compensation, is seen as a key move towards transforming into high-end raw materials, but the acquisition came with a high premium of 1182% [4] - The company’s cash reserves were significantly impacted by the acquisition, leaving only 110 million yuan in cash and equivalent, while short-term and long-term borrowings reached 25.02 million yuan and 18.8 million yuan, respectively [4] Group 3: R&D and Diversification Efforts - In an attempt to diversify revenue sources, the company has been exploring agency business and new drug development, with sales from its agency product, amoxicillin sodium and clavulanate potassium injection, reaching 19.57 million yuan, accounting for 13.01% of total revenue [6] - R&D investment increased by 54.21% in 2024 to 37.00 million yuan, representing 15.38% of revenue, but the low conversion efficiency is a concern, as the net profit excluding non-recurring items dropped by 1365.6% [6] - The company aims to accelerate the commercialization of intermediate and peptide raw material projects and develop derivatives of sodium acetate Ringer's injection, but the success of these strategies depends on the integration efficiency of acquired assets and the speed of new product pipeline development [7]

Core Viewpoint - Duori Pharmaceutical's 2024 annual report reveals a significant decline in revenue and profit, primarily due to the heavy reliance on sodium acetate Ringer's injection sales, which have been adversely affected by healthcare cost control and centralized procurement policies [1][2] Financial Performance - The company's total revenue for 2024 was 241 million yuan, a year-on-year decrease of 28.02% [1] - The net profit attributable to shareholders was -62.67 million yuan, marking a transition from profit to loss [1] - Revenue from sodium acetate Ringer's injection, the main product, fell to approximately 120 million yuan in 2024, a nearly 50% decline compared to previous years [2] Product Dependency and Risks - Sodium acetate Ringer's injection accounted for 77.63% of total revenue in 2024, with a 41.61% year-on-year decline in sales [1][2] - The company acknowledges the risk of having a single product structure, which has led to significant revenue volatility [2] Strategic Initiatives - To counteract declining sales, the company is accelerating the development of new products, including several injection solutions that are currently in the review stage [3] - Duori Pharmaceutical has made strategic acquisitions, including a 70% stake in Shanghai Jianling Biotechnology Co., aiming to expand its raw material drug production capabilities [4] Acquisition Details - The acquisition cost 271 million yuan, which raised concerns about the company's financial stability given its cash reserves of 329 million yuan as of June 30, 2024 [5] - The company has taken on additional debt to finance the acquisition, increasing its contingent liabilities significantly [6] Performance of Acquired Assets - The newly acquired Shanghai Jianling has not yet contributed positively to the company's financials, with reported revenues of 11.21 million yuan and a net loss of 32.53 million yuan for 2023 [6][7]

Core Insights - 康缘药业 reported a revenue of 3.898 billion yuan in 2024, a year-on-year decrease of 19.86%, and a net profit attributable to shareholders of 392 million yuan, down 15.58% [1] - The decline in performance is primarily attributed to the underperformance of core products such as 热毒宁注射液 and 银杏二萜内酯葡胺注射液, with injection products revenue dropping to 1.341 billion yuan, a decrease of 38.33% year-on-year [1][2] - The company completed a 100% acquisition of 中新医药, which focuses on the development of innovative biopharmaceuticals, enhancing its presence in the biopharmaceutical sector [3] Revenue and Product Performance - Core products contributing over 10% to revenue include 热毒宁注射液, 金振口服液, and 银杏二萜内酯葡胺注射液, with significant declines in sales volume and increased inventory levels for these products [1] - The market competition has intensified due to stricter medical insurance cost control and centralized procurement policies, leading to a substantial drop in sales for key products [2] R&D and Future Outlook - 康缘药业's R&D expenditure was 638 million yuan in 2024, a decrease of 24.66% year-on-year, but still represents 16.79% of total revenue, indicating a commitment to innovation [4] - The company has made progress in obtaining new drug approvals across various categories, but the conversion of R&D results into market competitiveness remains a critical challenge [5] - Future strategies to boost performance amidst declining core product sales and reduced investment in R&D are essential for 康缘药业's recovery [5]