Investment Rating - The report maintains an "Overweight" rating for the innovative pharmaceutical and medical device industry chain [3][5][6]. Core Insights - The report emphasizes the continuous recommendation of innovative drugs and medical devices, highlighting the high growth potential in the innovative pharmaceutical sector. It maintains "Overweight" ratings for companies such as Heng Rui Medicine, Hansoh Pharmaceutical, and others, indicating a potential for value re-evaluation [3][5]. - The report notes that the National Medical Insurance Administration has officially announced the 2025 medical insurance drug catalog, which includes 114 new drugs, 50 of which are first-class innovative drugs. This adjustment is seen as a validation of the support for innovation in the healthcare sector [3][5]. - The A-share pharmaceutical sector underperformed the broader market in the second week of December 2025, with the SW Pharmaceutical Biotechnology index declining by 1.0% compared to a 0.3% drop in the Shanghai Composite Index [7][18]. Summary by Sections Section 1: Continuous Recommendation of Innovative Drugs and Medical Devices - The report highlights the sustained recommendation of innovative drugs and medical devices, with a focus on companies that are expected to see performance growth and value re-evaluation [5][6]. Section 2: A-share Pharmaceutical Sector Performance - In the second week of December 2025, the A-share pharmaceutical sector's performance was weaker than the overall market, ranking 16th among the primary industries [7][18]. Section 3: Hong Kong and US Market Performance - The report indicates that the Hong Kong pharmaceutical sector also underperformed, while the US pharmaceutical sector showed stronger performance compared to the broader market [18].

风格轮动模型方面， Q4 风格轮动模型发出小盘、成长信号。 行业轮动模型方面 ， 12 月，单因子策略、复合因子策略推荐配置的多头行业均涵盖电力设备 及新能源。 大小盘风格轮动 Q4 配置信号。 根据 2025 年 09 月 30 日的最新数据， 2025Q4 ，双驱轮动策略得出的综合分数为 -1 ，预测信号为小盘。 【金工】风格及行 业观点月 报（2025.12） 价值成长风格轮动 Q4 配置信号。 根据 2025 年 09 月 30 日的最新数据， 2025Q4 ，双驱轮动策略得出的综合分数为 -3 ，预测信号为成长。 行业轮动 11 月表现。 使用行业历史基本面、预期基本面、情绪面、量价技术面、宏观经济等维度的因子对各行业打分， 分别构建复合因子策略及单因子多 策略 。 11 月复合因子策略的 超额收益为 -0.58% ，单因子多策略的超额收益为 -0.83% 。 行业轮动 12 月观点。 单 因子多策略推荐配置的多头行业为银行、建筑、有色金融、非银行金融、电力设备及新能源。复合因子策略推荐的多头行业为通 信、综合金融、计算机、电力设备及新能源、电力及公用事业。 风险提示： 模型失效风险、因子失效风险、 ...

医药板块 11 月表现弱于大盘，但医药商业、中药及原料药表现相对较 好。A 股新增金新药业、亿方生物和特保生物，港股重点配置翰森、三 生制药等。美股标普医疗保健精选行业上涨 9.1%，跑赢标普 500 指数。 金新药业因估值便宜且主业稳健被新增至组合，其 LPA 项目在中国排名 前二，有望成为催化剂。亿方生物股价已跌至低点，TIKTOO 产品预计 未来半年内有授权可能，武田同类产品数据也将成为催化剂。 特保生物主要品种派格宾乙肝适应症获批，新患数量增加，长效 PEG- IFNα2b 集采影响逐步消除，预计明年派格宾将继续高增长，长效生长 激素获批并参加医保谈判，有望放量。 恒瑞医药研发管线强大，集采情况良好，12 月 5 日研发日值得关注。医 疗器械龙头公司具有长期配置价值，竞争格局稳定，终端招标持续复苏， 三季报显示许多企业迎来收入拐点。 预计 2025 年 Q4 及 2026 年医疗器械行业业绩复苏趋势将持续，神经 介入、神经外科等板块表现良好，IVD 行业在 2025 年面临量价承压， 但预计 2026 年出现拐点。 Q&A 国投海融医药对 2026 年的策略观点是什么？ 国投海融医药认为，2025 年 ...

Investment Rating - The report maintains an "Outperform" rating for A-Shares including Jiangsu Heng Rui Medicine, Sichuan Kelun Pharmaceutical, Huadong Medicine, Jiangsu Nhwa Pharmaceutical, Xiamen Amoytop Biotech, Zhejiang Jingxin Pharmaceutical, Innovent Biologics, WuXi AppTec, Hangzhou Tigermed Consulting, Lepu Medical, and APT Medical [2][4][29] - The report also maintains an "Outperform" rating for H-Shares including Hansoh Pharmaceutical Group, 3SBio, PATEO, Akeso, and related targets such as Innovent Biologics and WuXi AppTec (H-Shares) [2][7][29] Core Insights - The report continues to recommend the innovative drug and device industry chain [1][2] - In November 2025, the pharmaceutical sector underperformed the broader market, with the SW Pharma Bio index falling by 3.6% compared to a 1.7% drop in the SHCOMP [2][10] - The premium of the pharmaceutical sector to all A-Shares is currently at a normal level of 72.6% as of the end of November 2025 [17][22] Summary by Sections A-Shares Performance - The report highlights the A-Shares that are recommended for investment, maintaining an "Outperform" rating for several companies, including Jiangsu Heng Rui Medicine and Sichuan Kelun Pharmaceutical, among others [4][5] - The report notes that the pharmaceutical sector's performance was ranked 23rd among Shenwan's first-level industries in November 2025 [10][12] H-Shares Performance - The report indicates that the H-Shares pharmaceutical sector performed in line with the market, with the Hang Seng Healthcare index down by 0.1% and the biotech sector up by 0.4% in November 2025 [2][23] - Top gainers in the H-Shares market included Laekna, Inc. (+40%) and Clover Biopharmaceuticals, Ltd. (+22%) [23] U.S. Market Performance - The U.S. pharmaceutical sector outperformed the broader market in November 2025, with the S&P Healthcare Select Sector rising by 9.1% compared to a 0.1% increase in the S&P 500 [23]

Investment Rating - The report maintains an "Overweight" rating for the innovative pharmaceutical and medical device industry chain [3][5]. Core Viewpoints - The innovative pharmaceutical sector is experiencing high prosperity, with a recommendation for companies like Heng Rui Medicine, Hansoh Pharmaceutical, Sanofi Pharmaceutical, Kelun Pharmaceutical, and Enhua Pharmaceutical to maintain an "Overweight" rating. The report also suggests that Biopharma/Biotech companies such as Kelun Biotech, BeiGene, Baillie Gifford, Yimeng Biotech, Jingxin Pharmaceutical, Teva Biotech, WuXi Biologics, and Ailisi should also be rated "Overweight" as their innovative pipelines are gradually being realized and their performance is entering a growth phase. Additionally, it recommends CXO and upstream pharmaceutical companies like Haoyuan Medicine, Baipusais, WuXi AppTec, WuXi AppTec, and Tigermed to maintain an "Overweight" rating. The report highlights leading medical device companies such as United Imaging, Lepu Medical, Spring Medical, and Huatai Medical as having potential for recovery, also maintaining an "Overweight" rating [5][6]. Summary by Sections - **A-Share Market Performance**: In the third week of November 2025, the A-share pharmaceutical sector underperformed the broader market, with the Shanghai Composite Index falling by 3.9% and the SW Pharmaceutical and Biological Index declining by 6.9%, ranking 23rd among Shenwan's primary industries [7][9]. - **Hong Kong and US Market Performance**: The Hong Kong pharmaceutical sector also underperformed, with the Hang Seng Healthcare Index and the Hong Kong Biotechnology Index both down by 7.5%, while the US healthcare sector outperformed, with the S&P Healthcare Select Sector Index rising by 1.8% [17]. - **Valuation Metrics**: As of November 21, 2025, the pharmaceutical sector's premium level relative to the entire A-share market is at a normal level, with a current relative premium rate of 71.8% [13][16].

Investment Rating - The report maintains a focus on innovative pharmaceuticals and medical devices, highlighting key A-share and H-share targets for investment [6][32]. Core Insights - The pharmaceutical sector showed a good recovery in Q3 2025, with overall revenue increasing by 0.6% year-on-year and net profit attributable to shareholders rising by 0.3% year-on-year [11][32]. - Medical equipment benefited from procurement recovery, with Q3 revenue and net profit growth of 10.6% and 0.6% year-on-year, respectively [11][32]. - Medical R&D outsourcing continued to achieve high growth, with Q3 revenue and net profit growth of 10.9% and 47.9% year-on-year [11][32]. - The offline pharmacy sector improved, with Q3 revenue and net profit growth of 2.1% and 37.8% year-on-year [11][32]. Summary by Sections 1. Focus on Innovative Pharmaceuticals and Medical Devices - Key A-share targets include Jiangsu Heng Rui Medicine, Sichuan Kelun Pharmaceutical, Huadong Medicine, Changchun High-tech Industry, Jiangsu Nhwa Pharmaceutical, WuXi AppTec, Hangzhou Tigermed Consulting, Lepu Medical, APT Medical, and related target Guangdong Zhongsheng Pharmaceutical [6][32]. - Key H-share targets include Hansoh Pharmaceutical Group, 3SBio, Akeso, and related target Innovent Biologics, WuXi AppTec [6][32]. 2. Q3 2025 Pharmaceutical Sector Recovery - The pharmaceutical sector's overall revenue increased by 0.6% year-on-year, with net profit attributable to shareholders up by 0.3% year-on-year [11][32]. - Specific segments such as medical devices and medical R&D outsourcing showed significant growth [11][32]. 3. October 2025 Market Performance - In October 2025, the pharmaceutical sector underperformed the market, with the SW Pharmaceutical and Biological index falling by 1.8% while the SHCOMP rose by 1.9% [14][32]. - The relative premium of the pharmaceutical sector compared to all A-shares was at a normal level, with a current relative premium rate of 76.7% [23][32]. 4. Hong Kong and U.S. Market Performance - The Hong Kong pharmaceutical sector underperformed, with the Hang Seng Healthcare index falling by 11.1% [24][32]. - In contrast, the U.S. S&P 500 healthcare sector rose by 3.5% [24][32].

Investment Rating - The report maintains an "Overweight" rating for several pharmaceutical companies including Jiangsu Heng Rui Medicine, Hansoh Pharmaceutical Group, 3SBio, and Jiangsu Nhwa Pharmaceutical, with related targets such as CSPC Innovation Pharmaceutical [6][28]. Core Insights - The innovative drug sector is experiencing high prosperity, and the report continues to recommend innovative drugs and their industry chain. It highlights the recent global strategic collaboration between Innovent Biologics and Takeda, which is expected to catalyze the innovative drug market [6][29]. - The report notes that the A-Shares pharmaceutical sector underperformed the market in the fourth week of October 2025, with the SW Pharmaceutical and Biological index rising only 0.6% compared to a 2.9% increase in the SHCOMP [8][30]. - In the same period, the Hong Kong pharmaceutical sector also underperformed, while the U.S. pharmaceutical sector performed in line with the market [31][19]. Summary by Sections Continuous Recommendation of Innovative Drugs and Industry Chain - The report emphasizes the ongoing recommendation of innovative drugs and the industry chain, maintaining "Overweight" ratings for various companies including Heng Rui Medicine, Hansoh Pharmaceutical, 3SBio, and Nhwa Pharmaceutical. It also recommends Biopharma/Biotech companies with innovative pipelines and increasing performance, maintaining "Overweight" ratings for Innovent Biologics, Xiamen Amoytop Biotech, and others [6][28]. Performance of A-Shares Pharmaceutical Sector - In the fourth week of October 2025, the A-Shares pharmaceutical sector's performance was weaker than the overall market, with a 0.6% increase compared to the SHCOMP's 2.9% rise. The medical service, pharmaceutical commerce, and medical equipment sub-sectors showed relatively better performance [8][30]. Performance of Hong Kong and U.S. Pharmaceutical Sectors - The Hong Kong pharmaceutical sector underperformed the market with a decline of 0.8%, while the U.S. pharmaceutical sector matched the market performance with a 1.9% increase. Notable stock movements included significant gains for companies like WuXi AppTec and declines for Alphamab Oncology in Hong Kong [31][19].

Investment Rating - The report maintains an "Overweight" rating for the industry [3] Core Viewpoints - The report continues to recommend innovative pharmaceuticals and medical devices along the industry chain [2][7] - The performance of the pharmaceutical sector in September 2025 was weaker than the broader market, with the SW Pharmaceutical Biotech index declining by 1.7% compared to a 0.6% increase in the Shanghai Composite Index [16][22] - The report highlights that the medical service sub-sector performed relatively well, increasing by 1.8%, while medical devices and chemical preparations saw slight declines [22] Summary by Sections - **Investment Recommendations**: The report includes a list of A-share stocks with an "Overweight" rating, including Heng Rui Pharmaceutical, Kelun Pharmaceutical, East China Pharmaceutical, Changchun High-tech, Enhua Pharmaceutical, WuXi AppTec, Tigermed, Lepu Medical, United Imaging Healthcare, and Huatai Medical [7][9] - **Performance Analysis**: The report notes that the monthly portfolio of Guotai Junan Pharmaceuticals outperformed the pharmaceutical index in September 2025, with an average increase of 1.1% compared to a 0.7% increase in the overall pharmaceutical index [12][13] - **Market Comparison**: The report indicates that the pharmaceutical sector's premium level relative to all A-shares is currently at a normal level, with a relative premium rate of 77.5% as of the end of September 2025 [26][28]

Core Insights - The article highlights the recent movements of prominent fund managers in the public fund sector, focusing on their investment strategies and the performance of their funds in 2025 [1][2]. Group 1: Zhang Kun's Strategy - Zhang Kun has reduced his holdings in Meituan by 46.43% while increasing his position in Beike, indicating a continued focus on domestic demand logic [2][3]. - The E Fund Blue Chip Select Fund, managed by Zhang Kun, has a current scale of 34.943 billion and a year-to-date return of 12.85% [3]. - The fund's hidden heavyweights include Focus Media and Meituan, with Focus Media's holdings increasing by 13.76% [3]. - Zhang Kun believes that the current pessimism regarding domestic demand is unfounded and anticipates a positive feedback loop in domestic consumption [4]. Group 2: Ge Lan's Focus on Innovation - Ge Lan's China Europe Medical Health Fund has achieved a year-to-date return of 28.82%, with significant investments in the innovative drug sector [5]. - The fund's hidden heavyweights include Huadong Medicine and Zai Lab, with a notable increase of 2627.32% in holdings of Ailisi [5][6]. - Ge Lan emphasizes that innovation, consumption recovery, and domestic substitution will drive growth in the pharmaceutical industry in the second half of 2025 [6]. Group 3: Fu Pengbo's Growth Strategy - Fu Pengbo's Ruiyuan Growth Value Fund has a year-to-date return of 48.50%, leading among large-scale public funds [7]. - The fund has significantly increased its holdings in Alibaba and BYD by 161.10% and 184.78%, respectively, focusing on high-growth sectors like technology and manufacturing [7]. - Fu Pengbo plans to continue emphasizing sectors such as electronics, internet technology, and precision manufacturing, while also adapting to market conditions [8].

Core Viewpoint - The recent trend of fund subscription limits in China is aimed at ensuring stable fund operations and protecting the interests of existing fund holders, with nearly 50 active equity funds implementing subscription limits since July 2023 [2][11]. Fund Subscription Limits - On August 9, 2023, China Europe Fund announced subscription limits for two of its products: the China Europe Medical Innovation Fund with a limit of 100,000 yuan per single account and the China Europe Science and Technology Innovation Fund with a limit of 1,000,000 yuan, effective from August 11, 2023 [2][3]. - Prior to this, the China Europe Digital Economy Fund had already suspended large subscriptions over 1,000,000 yuan starting August 6, 2023 [2][11]. - The limits are seen as a response to the hot market conditions, with fund companies aiming to protect existing investors from dilution of returns due to large inflows [2][11]. Market Sentiment and Fund Management - Industry experts interpret the subscription limits as a cautious approach to the current high market levels, suggesting that fund companies are not necessarily pessimistic about the market but are focusing on stable fund management [2][11]. - The sentiment in the market is at a high level, and experts recommend maintaining a balanced allocation to manage potential volatility and rapid rotations in the market [11]. Performance and Strategy Insights - Fund manager Ge Lan expressed a long-term optimistic view on the innovative drug sector, highlighting the increasing global competitiveness of domestic companies in areas like ADC and dual antibodies [7]. - The China Europe Science and Technology Innovation Fund, managed by Shao Jie, focuses on the technology innovation sector, which has seen explosive growth this year due to advancements in AI [7][9]. - The subscription limits reflect a broader trend in the industry, with many funds adopting strict limits on daily subscriptions to ensure effective investment strategies and stable operations [9][11].