摘要 京泰控股构建了全球唯一的 AI 驱动的闭环生态系统，通过量子物理理论 设计分子结构，并利用机器人实验室产生高质量数据，验证并训练 AI 模 型，从而在物质发现领域保持领先地位。 公司深耕生物医药行业，与辉瑞、礼来等全球 Top20 药企建立了合作关 系，例如与辉瑞合作开发新冠口服特效药 Paxlovid，并与礼来在小分子、 大分子药物领域展开合作，获得技术平台授权使用费。 京泰控股的商业模式是为客户提供从靶点发现到临床前候选化合物阶段 的服务，收取服务费，并在管线授权后获得里程碑费用和销售分成，覆 盖产品全生命周期。 公司 AI 和机器人技术大幅提升药物研发效率，将传统 4-6 年的研发周期 压缩至两年以内，并能设计出更具新颖性的分子，突破人类经验局限。 京泰控股的大分子技术平台 Astex Fold 基于动态蛋白训练，在特定疾 病类型中准确度超过 AlphaFold，已与强生、优时比等公司达成合作， 并与礼来达成 3.45 亿美元的大规模合作协议。 公司积累了 2,600 万条化学反应数据，通过高通量技术和自动化系统持 续产生高质量数据，模型成功率超过 90%，显著优于行业水平。 京泰控股正将 AI ...

来源：科技日报 科技日报北京1月12日电 （记者张梦然）最新一期《自然》报告了美国斯坦福大学研究人员开发的一种 新型合成皮肤，其突破性地可同时改变质地与颜色。该技术未来有望应用于伪装、柔性机器人及先进显 示等技术领域。 自然界中，章鱼、乌贼等头足类动物通过控制皮肤中的色素细胞和肌肉组织，可在毫秒级时间内改变体 色与纹理，实现与环境完美融合。这种生物伪装机制，涉及复杂的神经调控系统，而人工材料想要同时 实现颜色与纹理的独立、可逆调控，一直是道难题。 此前已有研究分别实现了电致变色或变形材料，但将两者集成于同一柔性表面并实现独立控制，仍面临 材料兼容性、响应速度与耐久性等多重挑战。 受章鱼等动物改变皮肤外观的启发，研究人员此次开发出了可编程薄膜，能实现纹理与色彩的动态转 换。该材料初始状态平整无纹，遇水膨胀后即显现图案与色彩。 在同时发表的新闻与观点文章中，德国斯图加特大学研究人员指出："这种对色彩与纹理的双重独立控 制，构成了自然界中最精密的伪装系统之一。" 【总编辑圈点】 这项新研究模仿了章鱼等头足类动物的神奇"换肤"能力，造出了一种能同时改变表面质地和颜色图案的 新型合成皮肤，也就是一种可编程薄膜。它首次在 ...

在同时发表的新闻与观点文章中，德国斯图加特大学研究人员指出："这种对色彩与纹理的双重独立控 制，构成了自然界中最精密的伪装系统之一。" （文章来源：科技日报） 受章鱼等动物改变皮肤外观的启发，研究人员此次开发出了可编程薄膜，能实现纹理与色彩的动态转 换。该材料初始状态平整无纹，遇水膨胀后即显现图案与色彩。 利用电子束在薄膜上"刻写"图案，研究人员添加了产生色彩效果的光学层。这些变化发生迅速，多数色 彩转换耗时不到20秒，且材料进行数百次切换而性能不衰。根据皮肤接触液体的面不同，色彩与纹理还 能独立改变。 研究人员表示，此次成功证明方法的可行性，虽然当前每件装置仅能呈现单一图案，但未来版本有望实 现多图案显示、电子控制及大规模生产。 最新一期《自然》报告了美国斯坦福大学研究人员开发的一种新型合成皮肤，其突破性地可同时改变质 地与颜色。该技术未来有望应用于伪装、柔性机器人及先进显示等技术领域。 自然界中，章鱼、乌贼等头足类动物通过控制皮肤中的色素细胞和肌肉组织，可在毫秒级时间内改变体 色与纹理，实现与环境完美融合。这种生物伪装机制，涉及复杂的神经调控系统，而人工材料想要同时 实现颜色与纹理的独立、可逆调控，一直是 ...

美国科研人员从章鱼皮肤的拟态能力中得到启发，研制出能改变表面纹理的新材料，帮助更加逼真地呈 现各种外观。该技术有望用于制造新型显示器、能改变外观的可穿戴设备、擅长伪装的柔性机器人等。 在此前多项研究中，人们通过调整材料微观结构在纳米尺度上对光的作用，实现了对材料颜色的控制。 但表面纹理特征还难以调控，例如亮度、颗粒度等。章鱼等头足类动物能精细控制嵌在皮肤中的肌肉纤 维，调整皮肤表面对光线的散射作用，使原本光滑的皮肤迅速呈现出与岩石等环境相同的表面纹理，结 合改变颜色的能力，实现完美隐身。美国斯坦福大学的研究团队从中得到启发，利用一种聚合物材料吸 收和释放水分改变形态的特性，研制出了可分别调整颜色和纹理的"超表面"材料。相关论文已于近日发 表在英国《自然》杂志上。这种聚合物称为PEDOT:PSS，吸水后会膨胀，在接触异丙醇等液体后会释 放水分并收缩，其形态改变是可逆的。研究人员将聚合物薄膜覆盖在基底上，用电子束辐照改变不同部 位聚合物的吸水性，在表面生成需要的"地形"，精细度可达到微米级别。通过微流控技术，研究人员使 聚合物表面接触不同浓度的异丙醇溶液，就能让"地形"发生改变，呈现出不同纹理。与以往方法不同的 ...

Core Insights - Researchers in the United States have developed a new material inspired by the camouflage ability of octopus skin, which can change surface texture to create realistic appearances for various applications [1][2] - This technology has potential uses in manufacturing new types of displays, wearable devices that can alter their appearance, and flexible robots capable of camouflage [1] Group 1: Material Development - The polymer material, known as PEDOT:PSS, expands when absorbing water and contracts when releasing moisture upon contact with isopropanol, allowing for reversible shape changes [2] - Researchers utilized electron beam irradiation to modify the water absorption properties of different areas of the polymer film, creating desired surface "topographies" with micron-level precision [2] Group 2: Technological Advancements - Unlike previous methods, this technology allows for dynamic activation and deactivation of textures without altering color, enabling realistic dynamic appearances [2] - The flexible substrate used in this thin-film system allows for easy integration into products of various shapes and sizes [2]

中化新网讯 近日，石墨烯材料领域学术研究获新突破。中国科学院宁波材料技术与工程研究所联合瑞 士联邦材料科学与技术研究所、德国马克斯-普朗克高分子研究所，制备出一系列具有周期性卟啉边缘 拓展的锯齿形石墨烯纳米带材料。相关研究成果发表在《自然-化学》上。 石墨烯纳米带作为一维石墨烯材料，因其非零带隙和可调控的能带结构，在半导体器件、自旋电子学及 量子技术等领域具有应用前景。将卟啉结构引入石墨烯纳米带中，有望通过d-π电子间的杂化作用，调 控纳米带的电子结构与物理化学性质。 这一研究为原子级精确的卟啉—锯齿边缘石墨烯纳米带杂化体系的构建提供了新方法，并通过金属中心 的灵活调控，为未来开发高性能半导体、化学传感器及量子自旋链等器件，提供了材料平台。 ...

Core Insights - Hubei Province has achieved a historic high with 11 scientists being elected as new academicians in the 2025 "Two Academies" selection, marking a significant milestone in the region's scientific community [4] Group 1: New Academicians and Their Contributions - New Chinese Academy of Sciences academician Yin Zhouping has developed inkjet printing equipment for display manufacturing and advanced bonding technology for chip manufacturing, contributing to the integrated circuit industry [3] - New Chinese Academy of Sciences academician Tang Huiming has established an integrated landslide prevention system, shifting disaster response from post-disaster rescue to pre-disaster warning [3] - New Chinese Academy of Engineering academician Liu Quansheng has created innovative results in deep resource development, generating over 20 billion yuan in economic benefits across more than 40 major national projects [3] Group 2: Emerging Innovations and Achievements - The Hubei Province has a strong educational foundation, with a high number of national science and technology awards and numerous key laboratories, contributing to a robust innovation ecosystem [5] - Significant breakthroughs in key technologies include the development of a 100nm silicon-based gallium nitride RF PDK and intelligent shield tunneling adaptive control technology [6] - The "Wuhan No. 1" satellite, developed by Wuhan University, has achieved positioning accuracy better than 5 meters, with weight and cost significantly lower than comparable international satellites [7] Group 3: Future Directions and Goals - Hubei aims to enhance its original innovation capabilities and establish a major technology infrastructure cluster, positioning Wuhan as a nationally influential technology innovation center [8] - The province plans to promote collaborative innovation between enterprises and research institutions, implementing favorable policies for R&D expenses and enhancing the commercialization of scientific achievements [8] - Hubei's industrial enterprises' R&D institution coverage has increased from 12.96% in 2020 to 31.8% currently, indicating a growing commitment to technological advancement [7]

美国研究人员开发出一种新型3D打印智能复合材料，可使脆性陶瓷具备弯曲、吸能及承受重载荷的能力，且能实现全工业规模生产。 这一创新解决了材料科学领域最棘手的难题之一：让形状记忆陶瓷在规模化生产时不破裂。它可能改变工程师设计承受应力、振动和冲击结构的方式。 研究由弗吉尼亚理工学院暨州立大学（Virginia Tech）材料科学与工程副教授Hang Yu博士领导，他自麻省理工学院博士后阶段起就致力于解决该问题。 Yu在新闻稿中指出："这项研究首次使用可规模化的固态3D打印工艺制造出块状形状记忆陶瓷-金属基复合材料。" 团队认为，这一突破可应用于广泛领域，包括国防系统、航空航天、基建和体育用品的减振与吸能。例如，嵌入陶瓷的金属可用于高尔夫球杆杆身，在保持 轻量化的同时减少振动。Erb说："这种复合材料为已有特定应用的金属增加了新功能。" 该研究凸显了弗吉尼亚理工在先进制造领域的优势。Yu在国家科学基金会和美国陆军研究实验室的支持下，一直在探索增材摩擦搅拌沉积的应用。 Yu总结道："这种复合材料非常有趣，陶瓷的形状记忆功能是我博士后阶段就开始研究的。现在我能将这两个兴趣结合，开发新的关键应用，这非常令人兴 奋。" 但此 ...

Core Viewpoint - TaiLi Technology (301595) is actively engaging with robot manufacturers to explore the application of its self-developed nano-fluid materials for flexible protective layers and glove fabrics [1] Group 1 - The company has developed nano-fluid materials that can support the underlying materials for flexible protective layers in robots and glove fabrics [1] - Technical exchanges and business connections with relevant robot manufacturers are currently underway [1] - Further verification and optimization of specific application scenarios are needed [1]

Group 1: DeepSeek AI Model - The Chinese AI company DeepSeek launched its open-source model DeepSeek-R1, which has gained global attention due to its low training costs and high performance in tasks like mathematical reasoning and code generation [2][3] - DeepSeek-R1's core competitiveness lies in its systematic innovation in computational efficiency, demonstrating that top-tier reasoning capabilities can be achieved without massive labeled data, significantly reducing training costs [2][3] - The model's open-source approach breaks technological monopolies, allowing developers worldwide to participate in its ecosystem, which has attracted hundreds of thousands of developers [2] Group 2: Nuclear Fusion and Quantum Computing - China's "artificial sun," the EAST device, achieved a world record by maintaining a plasma temperature of 100 million degrees Celsius for 1000 seconds, marking a significant step towards practical nuclear fusion energy [4] - The superconducting quantum computing prototype "Zuchongzhi 3" was developed, showcasing a computational speed that is a trillion times faster than the current fastest supercomputers, indicating a major advancement in quantum computing capabilities [5][6] Group 3: Advanced Materials and Brain-Computer Interfaces - A research team successfully created large-area two-dimensional metallic materials, marking a significant breakthrough in the field of two-dimensional materials [7] - China initiated its first invasive brain-computer interface clinical trial, allowing participants to control devices through thought, utilizing advanced flexible neural electrodes that minimize brain tissue damage [8][9] Group 4: Lunar Exploration and Plant Biology - The Chang'e 6 mission revealed the evolutionary history of the moon's far side, providing insights into volcanic activity and magnetic fields, which are crucial for understanding lunar geology [11][12] - A research team uncovered the molecular mechanisms behind how a single plant cell can develop into a complete plant, addressing a long-standing scientific question in plant biology [13] Group 5: Technological Innovations in Computing - Researchers developed a high-precision, scalable analog matrix computing chip, achieving digital-level precision in analog computing, which could revolutionize computational tasks in AI and communications [14][15] Group 6: National Strategic Initiatives - The 20th Central Committee of the Communist Party of China emphasized the importance of technological innovation in its strategic planning for the next five years, aiming to enhance China's technological self-reliance and drive new productive forces [16][17] Group 7: Military Advancements - China's first electromagnetic catapult aircraft carrier, Fujian, was commissioned, representing a leap in naval technology by utilizing advanced electromagnetic launch systems, enhancing operational capabilities [18]