Core Viewpoint - The company, Aihuilong (688575.SH), has recently received a medical device registration certificate from the Guangdong Provincial Drug Administration for its product, the Soluble Growth Stimulating Expression Gene 2 Protein Detection Kit (Chemiluminescence Method) and Chemiluminescence Immunoassay Analyzer [1] Group 1 - The product is aimed at enhancing diagnostic capabilities in the medical field [1] - The registration certificate signifies regulatory approval, which is crucial for market entry and commercialization [1] - This development may open new revenue streams for the company in the healthcare sector [1]

香港交易及結算所有限公司、香港聯合交易所有限公司與證券及期貨事務監察委員會對本申請版本的內容 概不負責，對其準確性或完整性亦不發表任何意見，並明確表示概不就因本申請版本全部或任何部分內容 而產生或因倚賴該等內容而引致的任何損失承擔任何責任。 Shenzhen Mindray Bio-Medical Electronics Co., Ltd. 深圳邁瑞生物醫療電子股份有限公司 （「本公司」） （於中華人民共和國註冊成立的股份有限公司） 的申請版本 警告 本申請版本乃根據香港聯合交易所有限公司（「聯交所」）及證券及期貨事務監察委員會（「證監會」）的要求 而刊發，僅用作提供資料予香港公眾人士。 本申請版本為草擬本，其內所載資料並不完整，亦可能會作出重大變動。 閣下閱覽本文件，即代表 閣 下知悉、接納並向本公司、本公司的聯席保薦人、整體協調人、顧問或承銷團成員表示同意： 本公司招股章程根據香港法例第32章《公司（清盤及雜項條文）條例》送呈香港公司註冊處處長登記前，本 公司不會向香港公眾人士提出要約或邀請。倘在適當時候向香港公眾人士提出要約或邀請，有意投資者務 請僅依據於香港公司註冊處處長註冊的本公司招股章程作出投資決 ...

Group 1 - The overall revenue and net profit of the IVD sector in A-share listed companies declined in Q2 2025, with a year-on-year decrease of 10.3% in revenue and 18.4% in net profit [2] - The gross profit margin for the sector slightly decreased to 57.3% in Q2 2025, attributed to the impact of medical reform policies such as DRG/DIP payment reforms [2][3] Group 2 - The medical reform has led to a decline in IVD product prices, creating a significant opportunity for domestic companies to replace imports [3] - Companies like Mindray and New Industries are experiencing revenue declines but are positioned to capture market share due to their relatively low market penetration in key segments [3] - The international IVD market presents substantial growth potential, being 4-5 times larger than the Chinese market, with emerging markets like China, India, Turkey, Russia, and Brazil showing rapid growth [4]

Core Insights - The IVD sector is experiencing a decline in revenue and net profit in Q2 2025, attributed to intense competition, regulatory changes, and pricing pressures [1][2][3] Group 1: Financial Performance - In Q2 2025, the overall revenue of the A-share IVD sector decreased by 10.3% year-on-year, while net profit fell by 18.4% [2] - For the first half of 2025, the sector's total revenue declined by 10.0%, and net profit decreased by 17.1% [2] - The gross profit margin for the sector was 57.3% in Q2 2025, showing a slight decline compared to the previous year [2] Group 2: Market Dynamics - The domestic IVD market is facing challenges due to fierce competition and delays in hospital procurement caused by industry restructuring [1][3] - The implementation of DRG/DIP payment policies has led to a reduction in testing volumes for certain diagnostic projects, contributing to price declines for reagent products [1][3] Group 3: Opportunities for Growth - The trend towards import substitution is gaining momentum, with significant market potential for domestic products as IVD prices decline [3] - Companies like Mindray and New Industries are leveraging their market positions to enhance their share in the IVD sector, despite revenue declines [3] - The international IVD market presents substantial growth opportunities, being 4-5 times larger than the Chinese market, with emerging markets showing rapid growth [4]

Investment Rating - The industry rating is maintained at "Outperform" [2] Core Insights - The in vitro diagnostics (IVD) sector is experiencing a favorable trend in international expansion, with companies accelerating their global strategies. However, the sector faced a decline in revenue and net profit in Q2 2025 compared to the previous year, attributed to various market pressures and policy changes [3][10] - The overall revenue for the A-share IVD sector decreased by 10.0% year-on-year in H1 2025, with net profit down by 17.1% and non-recurring net profit down by 26.3% [3][10] - The gross profit margin for the sector was 57.7% in H1 2025, slightly down from the previous year, primarily due to the impact of medical reform policies [3][10] - The domestic market is facing price declines for IVD products due to intense competition and regulatory changes, creating opportunities for domestic companies to increase market share through import substitution [3][10] - The international market for IVD is significantly larger than China's, with growth potential in emerging markets such as India, Turkey, Russia, and Brazil [3][25] Summary by Sections 1. IVD Mid-Year Report Analysis - The IVD sector's revenue and net profit saw a decline in H1 2025, with a 10.0% drop in revenue and a 17.1% drop in net profit year-on-year [3][10] - The gross profit margin decreased slightly, indicating ongoing cost control efforts amid challenging market conditions [3][10] 2. Subsector Analysis - The immunodiagnostics market remains stable, but the implementation of centralized procurement and DRG policies is slowing growth [17] - High-end technology transformation and international expansion are key strategies for companies to navigate current challenges [17] 3. Related Company Mid-Year Summaries - Mindray Medical reported a revenue of 64.24 billion yuan in H1 2025 for its IVD segment, a decrease of 16.11% year-on-year, but it has a significant opportunity to increase market share due to low penetration rates [10][16] - New Industries achieved a revenue of 21.81 billion yuan in H1 2025, with a slight decline of 1.12%, and is focusing on high-end products to strengthen its market position [10][16] - Aihuilong's self-produced IVD revenue was 6.71 billion yuan, down 14.98%, but it is steadily increasing its installed base of self-produced instruments [10][16]

Core Insights - The company held a performance briefing for the first half of 2025, focusing on advancements in cutting-edge technology platforms such as fluorescence, biochemistry, and chemiluminescence to enhance competitiveness in the high-end IVD market [1] - The chemiluminescence platform, a core technology for immunodiagnostics, is being prioritized by the company, which is enhancing its existing chemiluminescence reagent menu and upgrading its POCT chemiluminescence platform [1] - A new generation of chemiluminescence immunoassay analyzers was successfully developed in the first half of 2025, achieving international leading levels in detection speed, sensitivity, and the number of detectable items, catering to diverse clinical testing needs [1] - A series of chemiluminescent diagnostic reagents developed alongside the new analyzer have reached significant milestones, with some products currently in the registration process and set to enter the market soon [1] - These technological breakthroughs and upgrades are expected to lay a solid foundation for the company's future development in the high-end IVD market, potentially creating new profit growth points in the second half of the year and beyond [1]

Investment Rating - The investment rating for the company is not explicitly stated in the provided documents, but the analysis suggests a positive outlook based on growth potential and market positioning [1][2]. Core Views - The company has shown steady growth in overseas markets, with a significant increase in revenue from overseas operations, which reached 9.52 billion yuan, a year-on-year increase of 19.57% [2]. - Domestic market performance is under pressure due to various external factors, leading to a decline in revenue to 12.29 billion yuan, a year-on-year decrease of 12.81% [2]. - The company is focusing on enhancing its product offerings, particularly in the mid-to-large instrument segment, which is expected to drive reagent sales growth in the future [2]. - Profitability is projected to improve as reagent consumption recovers, with a forecasted sales gross margin of 68.44%, down 4.17 percentage points year-on-year [2]. Financial Summary - For the first half of 2025, the company reported total revenue of 21.85 billion yuan, a slight decrease of 1.18% year-on-year, and a net profit of 7.71 billion yuan, down 14.62% year-on-year [1][2]. - The company anticipates revenue growth from 2025 to 2027, with projected revenues of 48.95 billion yuan, 58.65 billion yuan, and 70.07 billion yuan, representing year-on-year growth rates of 7.9%, 19.8%, and 19.5% respectively [2][3]. - The expected net profit for the same period is projected to be 18.68 billion yuan, 22.29 billion yuan, and 27.51 billion yuan, with corresponding growth rates of 2.2%, 19.3%, and 23.4% [2][3].

Core Viewpoint - In the first half of 2025, Mindray Medical reported a significant decline in revenue and net profit, primarily due to domestic market challenges and intensified competition in the medical device sector [1][2][3] Financial Performance - Revenue for the first half of 2025 was approximately 16.743 billion yuan, a year-on-year decrease of 18.45% - Net profit was around 5.069 billion yuan, down 32.96% - Operating cash flow decreased by 53.83% to about 3.922 billion yuan [1] Business Segments - The in-vitro diagnostics (IVD) segment generated revenue of approximately 6.424 billion yuan, a decline of 16.11%, with a gross margin decrease of 4.37% to 59.5% - The medical imaging segment reported revenue of 3.312 billion yuan, down 22.51% - The life information and support segment had revenue of 5.479 billion yuan, a decrease of 31.59% [2][3] Domestic Market Challenges - Domestic business faced a decline of over 30%, attributed to healthcare reform, industry regulation, and oversupply during the pandemic - The company anticipates a market recovery starting in Q3 2025, with improved revenue growth expected [1][2] International Business Growth - International revenue accounted for approximately 50% of total revenue, with a year-on-year growth of 5.39% - The international IVD business experienced double-digit growth, while the international medical imaging segment saw mid-single-digit growth [3][4] Future Outlook - The company believes the most challenging period for domestic operations has passed and is focusing on market share growth, particularly in the IVD sector - Mindray is investing in high-value consumables and international markets, expecting significant growth in these areas [2][4] R&D and Financial Position - R&D expenditure for the first half of 2025 was 1.777 billion yuan, representing 10.61% of revenue - As of June 30, 2025, the company held cash and cash equivalents of approximately 16.967 billion yuan [4]

Investment Rating - The investment rating for the company is "Accumulate" (maintained) [2][5][8] Core Views - The company's overall performance declined in the first half of 2025, primarily due to domestic market pressures, with domestic revenue down 12.81% to 12.29 billion yuan. However, overseas business showed strong growth, with revenue increasing by 19.57% to 9.52 billion yuan, driven by a rise in instrument installations and a growing share of overseas revenue [3][4] - The company is focusing on high-end product development, achieving significant market validation. In the domestic market, 774 units of the chemiluminescence immunoassay analyzer were installed, with large machines accounting for 74.81% of installations. The company has also made breakthroughs in small molecule detection, with 14 new products approved for market [4][5] Financial Summary - For the first half of 2025, the company reported revenue of 2.185 billion yuan, a decrease of 1.18%, and a net profit of 771 million yuan, down 14.62%. The second quarter saw revenue of 1.060 billion yuan, down 10.88%, and a net profit of 334 million yuan, down 30.06% [2][3] - The company expects revenue to reach 4.567 billion yuan in 2025, with a slight growth of 0.7%, and net profit to be 1.761 billion yuan, a decrease of 3.7%. The projected earnings per share (EPS) for 2025 is 2.24 yuan [5][10]

Performance Overview - In 2024, the company achieved a total revenue of 4.535 billion, representing a year-on-year increase of 15% [1] - The net profit attributable to shareholders was 1.828 billion, up 11% year-on-year, while the net profit excluding non-recurring items was 1.720 billion, also up 11% [1] - In Q4 2024, the company reported revenue of 1.121 billion, a 10% increase year-on-year, but the net profit attributable to shareholders decreased by 5% to 445 million [1] - In Q1 2025, revenue was 1.125 billion, a 10% increase year-on-year, with net profit attributable to shareholders at 438 million, up 3% [1] Operational Analysis - The company experienced stable growth in annual performance, with an increasing proportion of high-end models [2] - Domestic revenue reached 2.843 billion in 2024, a 9.32% increase, with 1,641 units of chemiluminescence immunoassay analyzers installed, and large machines accounting for 74.65% of installations [2] - Overseas revenue was 1.684 billion, a significant increase of 27.67%, with 4,017 units sold and high-end models making up 67.16% of sales [2] - In Q1 2025, domestic revenue faced pressure due to inter-provincial alliance procurement policies, showing only a 0.11% increase, while overseas business maintained a strong growth rate of 27.03% [2] R&D and Innovation - The company invested 454 million in R&D in 2024, accounting for 10% of total revenue [3] - The high-throughput MAGLUMI X10 chemiluminescence immunoassay analyzer was launched in February 2024, enhancing user experience [3] - The fully automated nucleic acid detection analysis system, Molecision R8, received EU market access approval in March 2024, with domestic registration ongoing [3] Profit Forecast and Valuation - The company forecasts net profits attributable to shareholders of 2.148 billion, 2.648 billion, and 3.209 billion for 2025-2027, representing year-on-year growth rates of 18%, 23%, and 21% respectively [4] - The current price corresponds to a PE ratio of 19, 16, and 13 for the years 2025, 2026, and 2027 [4]