Di Yi Cai Jing
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创新药出海热潮下,这家药企为何收回对外授权
Di Yi Cai Jing· 2026-01-07 09:37
Core Viewpoint - The company Yiming Anke has decided to terminate its licensing agreement with Axion for two drug candidates, IMM2510 and IMM27M, and will reclaim all rights previously granted to Axion, including global development and commercialization rights outside Greater China [1] Group 1: Licensing Agreement Details - The initial licensing agreement with Axion began in August 2024, with a collaboration amount exceeding $2 billion [1] - Yiming Anke has received a total of $35 million in upfront and milestone payments from Axion prior to the termination of the agreement [1] Group 2: Reasons for Termination - The CEO of Yiming Anke stated that the collaboration with Axion had been pleasant, but the slow clinical progress due to funding constraints led to the decision to reclaim the rights [1] - Shareholders had been advising the company to reclaim the overseas rights for the two products, making this an opportune moment for the company [1] Group 3: Product Information - IMM2510 is a PD-L1/VEGF bispecific antibody, which is a significant target in tumor immunotherapy, and its potential to disrupt the PD-1 market is highly anticipated [2] - The market for PD-1/VEGF bispecific antibodies has seen increased activity since 2024, with notable deals such as the $1.25 billion upfront payment received by a competitor for a similar product [2] Group 4: Future Plans - Yiming Anke expressed confidence in the therapeutic potential of IMM2510 and IMM27M and aims to accelerate their clinical development [3] - The company plans to seek new business development partnerships with large multinational pharmaceutical companies, which will be simplified by reclaiming the rights from Axion [3]
今年起单位代扣代缴增值税 个人偷税将变难
Di Yi Cai Jing· 2026-01-07 09:23
以前个人自行申报缴纳增值税,而今年起付钱的单位需要替个人代扣代缴增值税,此前一些个人偷税情 形或不复存在。 今年起增值税法和增值税实施条例正式施行。其中,增值税法实施条例明确,自然人发生符合规定的应 税交易,支付价款的境内单位为扣缴义务人。代扣代缴的具体操作办法,由国务院财政、税务主管部门 制定。 上海国家会计学院副教授葛玉御告诉第一财经,以前个人要去税务局代开发票来缴纳增值税,但实际上 因各种原因,部分个人并没有缴税,而支付价款单位也没有代扣代缴义务。但今年起随着上述增值税法 实施条例实施,自然人增值税征管有了创新,引入了"支付方代扣代缴义务",以后境内单位就需要给个 人代扣代缴增值税。这将与"劳务费反向申请代开发票"形成组合拳,意味着对自然人的税收征管在逐步 加强。 葛玉御举例,比如专家教授给高校、企业授课,高校、企业给他支付劳务报酬,这属于典型的增值税应 税服务,未来单位不仅要代扣代缴个人所得税,还得代扣代缴增值税。 所谓代扣代缴指税收法律、行政法规明确规定的扣缴义务人,在支付款项时代税务机关从纳税人收入中 扣留并解缴税款的征管方式。比如很多企事业单位职工熟悉的单位代扣代缴个人所得税。 "而今年起增值税 ...
两个月股价涨超三倍偏离基本面,连续跨界的国晟科技今起被停牌
Di Yi Cai Jing· 2026-01-07 09:13
受困于光伏产业的周期,由园林业务跨界光伏后的国晟科技长期处于亏损状态。 因股价涨幅过高脱离基本面,国晟科技(603778.SH)今天起停牌,拟停牌时间不超过三个交易日。 国晟科技原名"乾景园林",以园林工程施工与景观设计业务起家,是国内生态园林主板上市第一股。 2020年至2022年的三年间,因园林业务需求萎缩及跨界转型的资金压力,乾景园林累计亏损超4亿元。 2022年11月,该公司以1.54亿元现金向国晟能源收购7家子公司股权谋求跨界光伏,并于2023年11月正 式改名为"国晟科技",主营业务从园林工程转变为"园林+光伏"双主业。 但受困于光伏产业的周期,此后的几年,国晟科技长期处于亏损状态。2023年和2024年的净亏损分别为 6888.01万元和1.06亿元,2025年前三季度净亏损为1.51亿元。 除了股价严重脱离基本面,另引起交易所关注的是,经营连年亏损、债台高筑的国晟科技的一系列高杠 杆对外投资操作。在锂电产业即将迎来新一轮周期反转的当口,国晟科技的第二次跨界瞄向固态电池和 锂电池关键配套部件。 2025年10月14日,国晟科技披露《关于对外投资暨关联交易的公告》称,二级控股子公司安徽国晟新能 源 ...
更多高价药有望用商保报销了 患者为何还难以获益
Di Yi Cai Jing· 2026-01-07 09:12
Core Viewpoint - The first edition of the "Commercial Health Insurance Innovative Drug Directory" has been implemented, which includes 19 innovative drugs with significant clinical value that exceed the payment capacity of basic medical insurance, potentially benefiting participants of the Huiminbao insurance program [1][3]. Group 1: Innovative Drug Directory - The directory includes drugs for critical areas such as tumors, rare diseases, neurodegenerative diseases, and metabolic diseases, filling gaps in the basic medical insurance catalog [1]. - CAR-T therapy is highlighted as a significant treatment option for difficult-to-treat blood cancer patients, with potential survival rates increasing from six months to over five years, although its high cost limits accessibility [1][3]. Group 2: Implementation Challenges - The successful use of these innovative drugs in hospitals remains a challenge, with some hospitals still navigating the application process for these drugs [2][3]. - The "three exclusions" policy allows drugs in the commercial health insurance directory to be excluded from basic medical insurance self-payment rate indicators and centralized procurement monitoring, but does not resolve the challenges of hospital access for these high-value drugs [3][4]. Group 3: Insurance Product Design - Some Huiminbao products have begun to integrate the innovative drug directory, offering increased reimbursement rates for drugs used during hospitalization [4][5]. - The reimbursement for innovative drugs is contingent upon their successful admission into hospitals, and if not, patients may not receive coverage for these drugs [4][5]. Group 4: Regulatory Support - Local medical insurance bureaus are encouraging retail pharmacies to stock drugs from the commercial health insurance innovative drug directory, which may help address the hospital admission challenges [5][6]. - There is ongoing dialogue between innovative drug companies and commercial insurance providers to explore the inclusion of these drugs in special drug directories, potentially bypassing hospital admission requirements [5][6]. Group 5: Coverage Variability - Some Huiminbao products show significant differences in reimbursement rates for pre-existing conditions versus non-pre-existing conditions, with non-pre-existing conditions receiving a higher reimbursement rate [5][6]. - Recent notifications from multiple local medical insurance bureaus support the design of new products by commercial insurance institutions based on the innovative drug directory to better meet patient needs and reduce medical costs [6].
今年起单位代扣代缴增值税,个人偷税将变难
Di Yi Cai Jing· 2026-01-07 09:11
葛玉御举例,比如专家教授给高校、企业授课,高校、企业给他支付劳务报酬,这属于典型的增值税应 税服务,未来单位不仅要代扣代缴个人所得税,还得代扣代缴增值税。 跟个税一样,未来单位也将代扣代个人应缴纳的增值税 以前个人自行申报缴纳增值税,而今年起付钱的单位需要替个人代扣代缴增值税,此前一些个人偷税情 形或不复存在。 今年起增值税法和增值税实施条例正式施行。其中,增值税法实施条例明确,自然人发生符合规定的应 税交易,支付价款的境内单位为扣缴义务人。代扣代缴的具体操作办法,由国务院财政、税务主管部门 制定。 上海国家会计学院副教授葛玉御告诉第一财经,以前个人要去税务局代开发票来缴纳增值税,但实际上 因各种原因,部分个人并没有缴税,而支付价款单位也没有代扣代缴义务。但今年起随着上述增值税法 实施条例实施,自然人增值税征管有了创新,引入了"支付方代扣代缴义务",以后境内单位就需要给个 人代扣代缴增值税。这将与"劳务费反向申请代开发票"形成组合拳,意味着对自然人的税收征管在逐步 加强。 当然,为了支持个人发展,目前国家出台了系列增值税优惠政策。 比如根据相关法规,个体工商户和其他个人未达到增值税起征点的,免征增值税。其中, ...
今日这些个股异动 主力加仓通信、银行板块
Di Yi Cai Jing· 2026-01-07 09:08
【振幅大】 -今日A股共有13只个股振幅超过20%; -惠同新材,天力复合、倍益康等个股振幅居前; 【换手率高】 -今日A股共有46只个股换手率超过30%; -C新广益,雷科防务、C陕旅等个股换手率居前; 【主力资金】 -主力资金今日净流入通信、银行、煤炭等板块,净流出国防军工、计算机、汽车等板块; -航天发展、格林美、北方华创、通宇通讯、南大光电资金净流入规模居前,分别净流入19.33亿元、 12.66亿元、12.57亿元、11.72亿元、8.80亿元; -雷科防务、海格通信、三花智控、立讯精密、东方财富资金净流出规模居前,分别净流出21.09亿元、 19.74亿元、19.26亿元、18.08亿元、17.91亿元。 (本文来自第一财经) ...
直击CES|爬楼梯扫地机、具身智能割草机……清洁电器智能大升级
Di Yi Cai Jing· 2026-01-07 09:05
Core Insights - The cleaning appliance industry is actively exploring embodied intelligence, but the realization of true commercial value remains a challenge, with the actual commercialization process dependent on the effectiveness of solving real-world problems [1][7] Group 1: Technological Advancements - Smart cleaning robots showcased at CES 2026 have advanced capabilities, including stair-climbing and robotic arms for tasks like picking up objects [2][3] - The integration of AI algorithms with robotic structures allows for enhanced mobility and cleaning efficiency, enabling robots to navigate complex environments autonomously [2][3] - Companies like Roborock and Dreame have introduced robots that can perform multi-level cleaning, addressing the needs of markets with multi-story homes [2][3] Group 2: Market Trends - The retail sales of Chinese robotic vacuum brands increased by over 50% year-on-year in the first three quarters of 2025, indicating a growing market for innovative cleaning solutions [3] - The introduction of new features and functionalities in cleaning robots is expected to drive market growth and expand applications into areas like health monitoring and elderly assistance [2][3] Group 3: Product Diversification - Companies are extending their product lines beyond indoor cleaning to outdoor applications, including lawn mowing and pool cleaning robots, which utilize advanced technologies for autonomous operation [6][7] - The introduction of intelligent companion robots reflects a trend towards enhancing user experience through emotional interaction and multi-modal perception [7] Group 4: Competitive Landscape - The competition in the global robotic vacuum industry is anticipated to intensify, focusing on AI technology and home ecosystem integration as key differentiators [7] - Companies are adopting varied technological approaches, with some emphasizing new forms, others focusing on functionality improvements, and some on software or hardware enhancements [7]
连板股追踪丨A股今日共98只个股涨停 脑机接口板块多股连板
Di Yi Cai Jing· 2026-01-07 08:54
| 美好医疗 | 3 | 脑机接口+机器人 | | --- | --- | --- | | 美克家居 | 3 | 家具 | | ST新华销 | 3 | 机器人 | | 南京熊猫 | 3 | 脑机接口 | | 引力传媒 | 3 | AI智能体 | | 盈新发展 | 2 | 存储芯片 | | 江顺科技 | 2 | 液冷服务器 | | 金风科技 | 2 | 风电 | | *ST宇顺 | 2 | 电子元件 | | 覆乘医药 | 2 | 中药 | | 北方导航 | 2 | 卫星通信 | | 鲁信创投 | 2 | 多元金融 | | 远东股份 | 2 | 人形机器人 | | *ST松发 | 2 | 船舶 | | ST嘉澳 | 2 | 化工 | | 胜通能源 | 2 | 液化天然气 | 脑机接口板块多股连板,创新医疗、岩山科技等3连板。一图速览今日连板股>> 第 顺经 | | 连板朋投 1.7 一板 | | | --- | --- | --- | | 股票名称 | 连板天数 | 所属概念 | | 锋龙股份 | 9 | 机器人 | | 雷科防务 | 6 | 商业航天 | | *ST东易 | 5 | 家装 | | 友邦吊顶 | ...
广发证券折价融资61亿港元,H股一度大跌5%
Di Yi Cai Jing· 2026-01-07 08:47
四、配售新 H 股和发行可转换债券) 1月6日晚间,广发证券(000776.SZ,01776.HK)公告称,拟以18.15港元/股的价格,发行股份,加上可转债共计融资61亿港元。7日,广发证券H股一度大 跌超过5%,一度跌破19港元;A股当天下跌2.61%,报收23.16元。 | 股东(附注 1) | | 于本公告日期 | | 紧随完成配售后但? 转换前 | | | --- | --- | --- | --- | --- | --- | | | 股份 | | 占已发行股 | | 占1 股1 | | | 类别 | 股份数目 | 份总数概约 | 股份数目 | 相先乡 | | | | | 百分比(%) | | E | | 吉林 敖东药业集 团股份有限公司 | A 股 | 1,252,768,767 | 16.47 | 1,252,768,767 | | | 辽宁成大股份有 | A 股 | 1.250.154.088 | 16.44 | 1.250.154.088 | | | 限公司 | | | | | | | 中山公用事业集 | A 股 | 686.754.216 | 9.03 | 686.754.216 | | ...