10日，记者从合肥综合性国家科学中心大健康研究院获悉，该院曹灿、王春玉团队联合中国科学技术大 学薛天团队、天津医科大学陈贺团队等，提出一种快速抗抑郁新策略，并设计出候选化合物 TMU4142，该化合物在动物实验中呈现显著的快速抗抑郁效果，且无明显副作用，为研发新一代快速 抗抑郁药物提供了新思路。相关成果日前在线发表于国际期刊《细胞》。 在研发过程中，研究团队注意到前人研究中报道不同脑区血清素1A受体，在下游信号传递中会"偏 好"结合不同G蛋白类型来发挥功能，中缝背核受体主要与Gi3蛋白结合，而海马体及皮质区的受体则主 要结合GoA蛋白。团队据此提出新策略：设计一种"偏好"激活GoA蛋白的化合物，在维持对GoA蛋白激 活能力的同时，弱化其对Gi3蛋白的激活，从而精准调控有益通路、规避延迟起效的有害效应。 研究团队以具有部分GoA蛋白激活特性的老药Pindolol为参考分子骨架，优化并合成了新候选化合物 TMU4142。在新奇食物抑制实验中，TMU4142注射1小时即可改善小鼠抑郁状态。神经化学检测进一步 证实，该化合物在治疗剂量下不会引发中缝背核区域自身受体介导负反馈作用。 曹灿表示，团队下一步将持续优化化合物 ...

据美国卡内基梅隆大学人机交互研究所官网最新消息，该机构针对主流大模型的研究发现，人工智能 （AI）在变得更"智能"的同时，其行为也变得更加"自私"。研究表明，具备推理能力的大型语言模型， 在社会互动中表现出更强的自我利益倾向，合作意愿更低，甚至可能对群体协作产生负面影响。这也意 味着，模型的推理能力越强，其合作性反而越弱。当人们借助AI处理人际关系冲突、婚姻问题或其他 社会性议题时，这类模型更可能提供鼓励"以自我为中心"的建议。 实验中，两个版本的ChatGPT被置于博弈情境：每个模型初始拥有100分，可选择将全部分数投入共享 池，或保留分数独享。结果显示，非推理模型在96%的情况下选择共享，而推理模型的分享率仅为 20%。仅增加五到六个推理步骤，合作行为就下降了近一半。 在群体实验中，当推理型与非推理型模型共同协作时，结果更为严峻。推理模型的自私行为表现出明显 的传染效应，导致原本倾向合作的非推理模型整体表现下降81%。这表明，高智能AI的个体决策不仅影 响自身，还可能破坏整个群体的协作生态。 这一发现对人机交互的未来发展具有深远意义。用户往往更信任"更聪明"的AI，容易采纳其看似理性的 建议，并以此为自身 ...

Core Insights - The successful launch of the KZ-1 rocket by Zhongke Aerospace on December 10, 2025, marked a significant achievement in commercial space endeavors, delivering nine satellites into their designated orbits [1] - The KZ-1 rocket features an innovative "deep measurement and control integration avionics system," which enhances reliability and allows for remote one-click launches, representing a shift towards a more generalized system design [1] - The launch included various satellites, such as the UAE 813 hyperspectral Earth observation satellite and several high-resolution remote sensing satellites developed by Changguang Satellite Technology Co., Ltd. [1] Group 1 - The KZ-1 rocket successfully completed its eleventh flight, having previously launched a total of 84 satellites, indicating a transition to large-scale production and regular operations [3] - Zhongke Aerospace has served 32 satellite clients, including six international customers, showcasing its growing presence in the global market [3] Group 2 - The Dongpo 15 satellite, developed by HuanTian Wisdom Technology Co., Ltd., aims to achieve sub-meter level Earth observation capabilities under all weather conditions [2] - The Yuxing No. 2 09 satellite, created by Xinghuo Chuanming (Beijing) Technology Co., Ltd., focuses on providing high-resolution infrared video data for applications in defense, meteorology, and emergency response [2] Group 3 - The Yixian-A satellite, developed by Sun Yat-sen University, is intended for scientific experiments, technology validation, and educational purposes [3] - The SPNEX satellite, a collaboration between the Egyptian Space Agency and the Egyptian Academy of Scientific Research and Technology, monitors climate change and ionospheric variations [3] - The Slippers2Sat satellite aims to provide support and education for marginalized communities in Nepal [3]

近日，2025腾冲科学家论坛发布首届腾冲青年科学家奖、十大论坛成果转化案例、十大学术成果、十大 科技合作计划等一系列成果。其中，由中国科技新闻学会参与编制的《2025全球低空经济与生态治理蓝 皮书》（以下简称《蓝皮书》）入选"十大学术成果"。《蓝皮书》提出，当前技术已不是低空经济规模 化发展的最主要瓶颈，制度协调与治理能力才是决定其成败的核心。 《蓝皮书》提出，当前，技术已不是低空经济规模化发展的最主要瓶颈，制度协调与治理能力才是决定 其成败的核心。报告分析了不同发展模式的利弊，并强调尽管路径各异，但"治理一致性"与制度的可预 测性是产业健康、规模化发展的前提。 《蓝皮书》由中国科技新闻学会联合新华网融媒体未来研究院、南京航空航天大学国际创新港城市空中 交通研究院、江苏天闳低空数字技术研究院共同编制。 《蓝皮书》提出，全球低空经济发展普遍面临金融脆弱性与治理碎片化两大瓶颈，而公众关注的焦点已 从单纯的"飞得安全"转向更广泛的"治理可信"，涉及噪音、隐私、数据安全与算法透明度等社会接受度 与产业合法性问题。《蓝皮书》强调，未来的产业合法性正从"展示性"场景走向"可验证的绩效"，强大 的合规与治理能力将成为国家与 ...

Core Viewpoint - The issue of color fading on the iPhone 17 Pro Max's star orange finish after using wet wipes has raised concerns about the durability of high-end electronic products and the cleaning methods used by consumers [1][2]. Group 1: Causes of Color Fading - Two main viewpoints exist regarding the cause of the color fading: one blames the use of wet wipes containing bleaching or strong oxidizing agents, while the other attributes it to potential production defects in the iPhone 17 Pro series [2]. - Apple’s customer service indicated that ordinary wet wipes should not affect the color, but those containing high concentrations of alcohol or acetone could lead to fading [2]. - The production process of the iPhone 17 Pro series, particularly the anodizing technique, plays a crucial role in the durability of the color finish, and any errors in this process could lead to color fading [5][6]. Group 2: Anodizing Process - The iPhone 17 Pro series utilizes a complex anodizing process that includes anodizing, dye coloring, and sealing to enhance surface hardness and corrosion resistance [5]. - Any mistakes in the anodizing process, such as improper bonding of the anodized layer to the aluminum substrate, can result in the layer peeling off, exposing the underlying metal [6]. - Variations in the durability of dye particles used for coloring can lead to fading under UV light or during cleaning, indicating that the choice of dye may have contributed to the issue [6]. Group 3: Cleaning Recommendations - To clean electronic devices safely, it is recommended to avoid direct application of cleaning liquids and instead use a microfiber cloth lightly dampened with distilled or purified water [7]. - Users should refrain from using harsh cleaning agents, including window cleaners or abrasive materials, to prevent damage to the device's protective layers [8]. - The popularity of products like touch-up paint pens and specialized cleaning wipes reflects consumer concern over maintaining the appearance of their devices [7].

Core Insights - The 14th China Innovation and Entrepreneurship Competition in the fields of new energy, new energy vehicles, and energy conservation and environmental protection concluded successfully in Hunan Xiangjiang New Area, with Huainan Yiheng Photovoltaic Technology Co., Ltd. winning an excellence award for its "monocrystalline perovskite solar cell" project [1][3]. Group 1: Competition Overview - Since its inception in 2012, the China Innovation and Entrepreneurship Competition has attracted over 380,000 enterprises and teams, becoming an important platform for promoting technological entrepreneurship and industrial upgrading [3]. - This year's competition saw nearly 30,000 enterprises registering, with 169 outstanding companies advancing to the national finals, aiming to promote key technological breakthroughs and facilitate industrial chain collaboration [3]. Group 2: Company and Technology Highlights - Huainan Yiheng Photovoltaic Technology Co., Ltd.'s award-winning project focuses on cutting-edge developments in the photovoltaic industry, specifically the next-generation perovskite solar technology, which is characterized by low material costs, simple preparation processes, and significant potential for photoelectric conversion efficiency [5]. - The technology developed by the company addresses challenges in large-scale production and long-term stability, which are critical for widespread adoption [5]. - The company's research team has pioneered two technologies: "colloidal-driven low-concentration supersaturated solution crystallization" and "molecular ferroelectric in-situ passivation," achieving high-quality inch-scale monocrystalline perovskite films [5]. - The new technology can enhance module efficiency to over 22%, extend lifespan beyond 25 years, and reduce production costs to about half of traditional crystalline silicon components, while also significantly lowering production energy consumption [5].

Core Insights - The article highlights the recognition of significant scientific figures in 2025, including Liang Wenfeng, founder of DeepSeek, and Du Mengran, a geologist at the Chinese Academy of Sciences, who were named in Nature's annual list of top ten personalities [7]. Group 1: Key Figures and Contributions - Liang Wenfeng's DeepSeek, launched in January, has made a remarkable impact in the AI field, demonstrating performance comparable to leading models while requiring only a fraction of the resources [7]. - DeepSeek's "open weights" approach allows for free download and expansion, benefiting researchers significantly [7]. - Du Mengran and her team explored an ecosystem over 9,000 meters below the sea surface, revealing unique biological discoveries [7]. Group 2: Other Notable Scientists - Tony Tyson from the University of California, Davis, contributed to the development of a digital camera technology for the Rubin Observatory, which aims to enhance the observation of distant galaxies [8]. - Ifat Melber from the Weizmann Institute of Science revealed a new dimension of the human immune system through her research on proteasomes [8]. Group 3: Biomedical Advances - Sarah Tabrizi from University College London proposed a therapy that slows the progression of Huntington's disease, a significant breakthrough after decades of research [9]. - A new gene-editing therapy has reportedly cured a rare disease in a child, showcasing advancements in rare disease treatment [9]. Group 4: Research Integrity and Public Health Initiatives - Achal Agrawal's work in India has highlighted issues of research integrity, leading to significant policy reforms in higher education rankings [9]. - Luciano Moreira established the first mosquito factory in Brazil to breed mosquitoes infected with Wolbachia bacteria, aiming to control the spread of dengue fever [9]. - Precius Masoso from the University of Cape Town facilitated the first global pandemic prevention agreement after extensive negotiations [9].

日前，第19届世界水资源大会在摩洛哥古城马拉喀什举行，会议以"变化世界中的水：创新与适应"为主题。作为国际水资源领域参会规模顶尖、全球影 响力深远、专业水平具有引领性的学术会议，大会吸引来自80多个国家和地区的2000多名全球专家齐聚，呼吁携手应对全球气候变化特别是极端天气事件增 多给水安全带来的严峻挑战。 治水之思：中国治水思路昭示世界意义 初冬的马拉喀什，暖阳高照。中国水利部部长李国英在开幕式上致辞中说，中国的基本水情一直是夏汛冬枯、北缺南丰，水资源时空分布极不均 衡。"节水优先、空间均衡、系统治理、两手发力"的治水思路，指引中国治水取得了历史性成就、发生了历史性变革。坚持节水优先，就是要从观念、意 识、措施等各方面把节水放在优先位置。坚持空间均衡，就是要树立人口经济与资源环境相均衡的原则，以水定城、以水定地、以水定人、以水定产，有力 有效平衡区域水资源和生产力布局需求。坚持系统治理，就是要深化流域统一治理管理，成功战胜严重水旱灾害，复苏河湖生态环境。坚持两手发力，就是 要充分发挥市场在资源配置中的决定性作用，更好发挥政府作用。 世界水理事会主席福勋指出，中国的治水经验正吸引着许多国家的密切关注与借鉴。中 ...

记者10日从中国科学院理化技术研究所获悉，研究团队在超高温工业热泵技术上取得系列重要进展，成 功研制出国际首台泵热温度超过200℃的双作用自由活塞型热声斯特林超高温热泵原型样机，为造纸、 印染、陶瓷、冶金等大量耗热工业领域提供了一种潜在的绿色高效供热新路径。相关成果已发表于《自 然·能源》《应用物理快报》等国际权威期刊。 这些突破表明，热声斯特林技术有望发展成为新一代超高温热泵的核心，助力工业领域替代化石燃料供 热，减少碳排放。研究团队还对超高温热泵未来的关键材料与技术发展方向进行了展望。 （文章来源：科技日报） 工业供热消耗了我国约40%的热能，其温度需求从100℃至1000℃以上不等。实现这些中高温热能的低 碳供应，是达成"双碳"目标的关键挑战之一。传统蒸汽压缩热泵难以突破200℃温区，且面临环保工质 短缺问题；二氧化碳热泵则受制于高压和能效瓶颈。 中国科学院理化所罗二仓研究员团队长期致力于采用氦、氩等天然环保工质的热声斯特林技术研究。该 技术具备工质安全、温区宽广、效率潜力高等优势。团队近期取得双重突破： 一方面，他们创新提出"反相运行"的声场调控机制，成功研制出国际上首台泵热温度超过200℃的双作 用 ...

Core Insights - The news highlights the efforts of Xixian New Area in Shaanxi Province to implement low-carbon energy solutions and promote sustainable practices across various sectors, including energy supply, agriculture, construction, and industry. Group 1: Energy Supply Innovations - The comprehensive energy supply project in Xixian New Area utilizes a "geothermal + gas" complementary system, achieving a heat output of 4.2 times the electricity consumed, resulting in an annual reduction of approximately 602 tons of CO2 emissions [1] - The area has established multiple integrated charging stations and all 21 centralized heating companies use clean energy for heating, with deep geothermal heating covering 15.8 million square meters [1] Group 2: Agricultural and Building Integration - The "photovoltaic + agriculture" project in Taiping Town generates 210 million kWh annually while reducing CO2 emissions by 168,000 tons, demonstrating a dual-use model that benefits local farmers [2] - A research building at Xi'an Jiaotong University achieves energy self-sufficiency by utilizing 23% of its facade for green electricity, integrating technologies like photovoltaics and IoT [2] Group 3: Industrial Decarbonization - Xixian New Area is attracting green projects and technological innovations, with over 80 hydrogen energy companies established, representing more than half of Shaanxi's hydrogen enterprises [3] - The RCBHR system developed by Xi'an Shengshi Youlian Energy Conservation Technology Co., Ltd. recovers approximately 67,200 tons of steam annually, generating 10 million kWh and reducing CO2 emissions by 20,000 tons [3] Group 4: Digital Transformation in Manufacturing - The digital green factory by Green Energy Hui Charging Technology Co., Ltd. extends decarbonization efforts across the entire supply chain, promoting green transformation among nearly 100 regional enterprises [4] - The company exports products to over 70 countries and has created more than 100 green jobs in Xixian New Area, engaging over 5,000 participants in low-carbon activities [4]