如何实现光在纳米甚至原子尺度上的精准操控与高效传播，一直是科学研究的前沿问题。近日，来自上 海交通大学、国家纳米科学中心、东北师范大学与香港大学的联合研究团队，提出了一种名为"声子工 程"的新策略，首次实现了超宽频带、几乎无衍射的极化激元定向传播。相关研究成果15日发表于《自 然·纳米技术》杂志。 "我们不再是被动地寻找满足动量匹配的体系，而是主动'设计'出理想状态。"论文共同通讯作者、上海 交通大学副教授郭相东说，"这为制造超紧凑、高性能的光子电路打开了一扇全新的大门，也为纳米光 子学与集成光电子学的未来发展注入强大动力。" "'声子工程'调控策略不仅解决了极化激元控制中的关键技术瓶颈，还具有较强的通用性和灵活性。"戴 庆说，借助该技术，未来有望在指甲盖大小芯片上集成强大的光子电路，推动信息技术向更高速、更低 功耗、更高密度方向发展。 （文章来源：科技日报） 然而，要将这一潜力转化为现实，首先必须解决一个核心难题：如何对极化激元进行高效且灵活的控 制。目前，该操控过程面临两大技术瓶颈。论文共同通讯作者、上海交通大学教授戴庆告诉记者："首 先是需要非常精确的'动量匹配'，就像两列火车要完美同步才能对接；其次是 ...

12月15日，工业和信息化部附条件许可了长安牌和极狐牌两款L3级自动驾驶车型产品，我国自动驾驶 汽车产业正式从"技术验证"迈向"量产应用"新阶段。 对自动驾驶而言，安全性是最核心的考量。此次获批上路的两家企业已按要求完成并通过了一系列产品 测试与安全评估。 孙航透露，相关安全评估并非单纯验证某项功能，而是对自动驾驶产品的安全性进行系统性、全流程考 核：一方面，考察企业在自动驾驶产品设计、开发、测试全过程中的安全保障能力；另一方面，通过第 三方实验机构测试、行业专家评审等，对具体车型的安全性能进行验证。 L3级自动驾驶的落地，是涵盖整车、零部件、软件算法、通信、数据服务等多主体协同的系统性工 程。业内人士表示，此次获批是在社会广泛关注和高度期待下，主管部门作出的重要安排，将带动新出 行、新保险等衍生业态发展。 何为L3级自动驾驶？即将开展的上路试点意味着什么？科技日报记者就此采访了有关专家。 第一问：何为L3级有条件自动驾驶？ 目前，我国将驾驶自动化分为0级到5级共6个级别。根据《汽车驾驶自动化分级》标准，L0代表完全由 人类驾驶，L1—L2属于驾驶辅助阶段，L3—L5则逐步过渡到有条件自动驾驶、高度自动驾驶， ...

Core Insights - The new National Medical Insurance Drug List and the first Commercial Insurance Innovative Drug List have been officially released, including over a hundred innovative drugs, set to be implemented on January 1 next year [1] Group 1: New Drugs Included in the Medical Insurance List - 98% of the drugs included in the medical insurance list are new drugs approved within the last five years, with 50 of them being first-class new drugs, marking a historical high [2] - A significant portion of the newly added drugs addresses high-demand conditions such as cancer, chronic diseases, and rare diseases, with 36 cancer drugs included, accounting for approximately 30% of the total [2] - The inclusion of innovative drugs is expected to alleviate clinical pain points, particularly for conditions previously lacking effective treatments, such as triple-negative breast cancer and pancreatic cancer [3] Group 2: Coverage and Clinical Value - The new medical insurance directory covers a wide range of diseases, including metabolic diseases and rare diseases, with drugs like KARS-targeted therapies now included [3] - Chronic disease medications, such as the cholesterol-lowering drug Increlex and the dual-target diabetes drug Tirzepatide, have also been added to the list [4] - The approval rate for drugs entering the expert review stage has decreased to 41.48%, with 331 drugs evaluated and only 129 passing the review [5] Group 3: Criteria for Inclusion - The "Four No Changes" principle restricts the inclusion of drugs that do not alter the main components, indications, administration routes, or clinical value, focusing on "true innovative" drugs that fill existing gaps [6] - Several first-class new drugs did not pass the expert review due to insufficient clinical value, despite being new compounds [7] - Experts emphasize the need to avoid homogenized innovation that wastes resources, advocating for genuine innovation that demonstrates real clinical benefits [8] Group 4: Commercial Insurance Innovative Drug List - The first Commercial Insurance Innovative Drug List includes advanced therapies such as CAR-T cell therapy, monoclonal antibodies, and small molecule targeted drugs, with 19 drugs included [10] - To facilitate the implementation of the commercial insurance innovative drug list, the National Medical Insurance Bureau has provided supportive measures, including exemptions from certain monitoring and payment frameworks [11] - The successful implementation of this new system requires careful consideration of actuarial pricing and the establishment of efficient communication platforms between commercial insurance and medical enterprises [11]

丙型肝炎病毒可导致慢性丙肝感染，全球约有5000万人长期感染，每年约造成24.2万人死亡，主要死因 是由此引发的肝硬化和肝癌。尽管丙肝可通过8—12周的药物疗程治愈，但由于价格低、易获取的检测 手段不足，治疗覆盖率依然偏低。 此次，研究团队基于自主研发的DASH®（特异性杂交诊断分析仪）平台，开发了针对丙肝检测的快速 聚合酶链式反应（PCR）。该平台此前已用于新冠病毒检测，此次通过技术优化，实现了利用全血样本 快速检测丙肝病毒RNA。 美国西北大学领导的研究团队开发出迄今最快的丙型肝炎病毒（HCV）检测技术，可在15分钟内给出 结果，比现有快速检测方案提速高达75%。这一速度对患者的治疗至关重要，有望预防并发症，甚至挽 救生命。相关研究成果发表于新一期《传染病杂志》。 （文章来源：科技日报） 团队成员表示，新技术可让患者在门诊就诊期间就完成检测，有望实现当日确诊、当日治疗，使更多患 者更早治愈，从而彻底改变丙肝防治方式。 为验证效果，研究人员将检测设备和试剂送往约翰斯·霍普金斯大学，由独立团队对97份临床样本进行 评估。结果显示，该检测设备与商用检测平台的结果一致率达到100%。 在常规流程中，PCR样本通常 ...

Core Insights - A collaborative research team from the University of Colorado Boulder and Sandia National Laboratories has developed a super-miniature optical phase modulator, which is only one-hundredth the diameter of a human hair, capable of controlling laser frequencies with extremely low power consumption and high precision, providing core support for future large-scale quantum computers [1][2] Group 1: Technological Advancements - The new optical phase modulator utilizes microwave frequency vibrations oscillating billions of times per second to precisely control the phase of lasers, efficiently generating stable new laser frequencies on a chip [1] - The device's microwave power consumption is approximately 1/80 that of various commercial modulators while achieving the same functionality [1] Group 2: Implications for Quantum Computing - Lower power consumption leads to reduced heat generation, allowing for more optical channels to be densely packed and even integrated on the same chip, enabling unified and precise control of laser frequencies and phases for a large number of atoms [2] - This advancement supports the realization of a powerful and scalable atomic control system, essential for quantum computing [2] Group 3: Manufacturing and Industry Impact - The device is manufactured using CMOS technology in a wafer fabrication facility, which is the most mature and scalable manufacturing technology in the modern chip industry, widely used in smartphones, computers, and various electronic devices [2] - This achievement is expected to drive the transition of optical technology from large, high-energy traditional optical devices to highly integrated, low-power photonic chip platforms [2]

美国密歇根州立大学研究团队利用捐赠的人类干细胞，成功开发出全球首个"人源化"心脏类器官，能在 暴露于炎症环境时表现出心房颤动特征。这一突破为研究心律失常提供了前所未有的活体人体组织模 型，有望打破该领域30多年来无新药问世的僵局。这项发表于《细胞·干细胞》的研究，标志着人类在 对抗心律失常的道路上迈出了关键一步。 心房颤动影响全球约6000万人，但由于缺乏准确的人类心脏模型，药物研发长期停滞。近30多年来，没 有新药物被开发用于治疗心房颤动。现有疗法往往针对症状而非潜在机制，因此人们对这种疾病仍然治 疗不力。 2020年起，密歇根州立大学发育与干细胞生物学部艾托·阿吉雷团队利用捐赠的人类干细胞，培育出直 径约数毫米的三维心脏类器官。这些类器官不仅拥有类似真实心脏的腔室结构和血管网络，还能自主节 律性跳动。而且这些类器官的节律性搏动非常强劲，无需显微镜即可观察到。 类器官大小与扁豆相仿，精确度极高，使团队能够以前所未有的方式研究心脏发育、疾病和药物反应。 此次研究的关键进展在于，团队首次在类器官中引入了免疫细胞。博士后研究员科林·奥罗克发现，当 类器官暴露于炎症环境时，会出现类似房颤的心律失常；而使用抗炎药物后 ...

Core Insights - Wankey Technology has been recognized in the "2025 China AI Annual Enterprises" list for its exploration of AI, product integration, and global market performance [1] - The evaluation focused on comprehensive strength, investment value, and development potential, selecting 10 representative pioneering companies [1] Group 1: Technological Innovation - In June, Wankey Technology established the "AI Video Large Model Laboratory" in collaboration with Huawei Cloud and released the Wankey Tianmu Audio-Video Multimedia Model 2.0, which shows an average performance improvement of about 90% compared to version 1.0 [1] - The new model excels in professional-level camera operation, three-dimensional sound effect generation, and intelligent frame transition [1] Group 2: Application and Product Development - Wankey Technology has enhanced its AI capabilities across its video, document, and drawing software product matrix [1] - The newly launched video creative product, Wankey Miaoying 2026, offers a one-stop experience from AI material generation to fine editing, significantly lowering the barriers for professional video creation [1] Group 3: Global Reach and User Base - Wankey Technology's products are available in over 200 countries and regions, with a cumulative active user base exceeding 2 billion, earning it the title of "Chinese version of Adobe" [2]

Core Insights - The 15th Cybersecurity Vulnerability Analysis and Risk Assessment Conference highlighted breakthroughs in the domestic innovation (信创) sector, particularly in software compatibility and interface consistency, which are reducing migration costs significantly [1][2] - The domestic software industry is transitioning from "tool replacement" to "productivity reconstruction," driven by innovations such as digital employees and intelligent knowledge bases [1] - The year 2025 is identified as a critical turning point for the domestic innovation industry, with the potential for market growth and deeper integration of domestic software solutions [1] Industry Developments - The domestic innovation sector is currently in a phase driven by "policy + technology + market," with ongoing cost pressures and technological breakthroughs facilitating implementation [1] - The announcement of a potential 33% price increase by Microsoft for commercial subscriptions starting in 2026 presents an opportunity for the domestic innovation office ecosystem [1] - The construction of a self-controllable office ecosystem is deemed essential for ensuring digital security and enhancing cost efficiency [1] Technological Advancements - Beijing Kingsoft Office Software Co., Ltd.'s WPS 365 has developed an AI collaborative office platform that integrates core AI products, marking a significant shift from "usable" to "user-friendly" domestic office software [1] - Document intelligent parsing is identified as a core entry point for office data flow, breaking foreign monopolies and contributing to a robust domestic technology foundation [1] - The integration of domestic software with national encryption algorithms and zero-trust architecture is creating a "smart + secure" technology system, providing viable upgrade paths for critical industries such as finance and energy [1] Market Outlook - The domestic innovation office sector is experiencing a tiered development pattern, with small and medium enterprises leading the way in basic replacements due to cost pressures, while large enterprises deepen their applications through AI capabilities [2] - The market size of China's domestic innovation industry is projected to exceed 20 trillion yuan by 2025, with office software being a core application driving the autonomous and controllable process across the entire industry chain [2] - The dual push from policy and market forces is accelerating the penetration of domestic innovation office software, which is expected to become a crucial support for the safe development of the digital economy in the next three years [2]

Core Insights - The construction industry is transitioning towards standardization, industrialization, intelligence, and sustainability through the integration of data elements and advanced technologies like BIM, prefabricated buildings, and robotic construction [1][7] Group 1: Technological Advancements - The use of robots in construction has significantly improved efficiency, with a plastering robot achieving a precision of 0.3 mm and completing 3 square meters per minute, which is four times faster than manual labor [1] - The competition showcased 146 innovative results from 109 units across over 20 provinces, highlighting the leap from "single-point technology breakthroughs" to "full-scene implementation" in smart construction [3] - Robots are now integrated into a systematic work network, utilizing BIM, FMS, and WMS systems to create a closed-loop of task execution and material delivery [3][4] Group 2: Collaborative Work Models - The collaborative operation of construction robots has transformed job sites, enhancing efficiency, quality, and safety while reducing reliance on human labor [4] - Advanced technologies are essential for the promotion of robots in construction, with modular intelligent controllers reducing development cycles by over 50% [5] Group 3: Smart Construction Applications - Smart construction is driven by data, enabling full-process collaboration and real-time monitoring of project design, production, and construction progress [6] - The integration of AI in construction has led to significant improvements, such as a 30% reduction in equipment failure rates and a 40% increase in yard turnover rates [7] Group 4: Expanding Application Scenarios - New application scenarios for smart construction are emerging, including drone inspections, wall-climbing robots for bridge diagnostics, and underwater robots for tunnel monitoring [8] - The city of Chongqing has developed ten typical applications in digital engineering, achieving a 70% reduction in pipeline damage incidents and a 100% digitalization rate in core business processes [8] Group 5: Policy and Investment - Chongqing is implementing a comprehensive policy approach to promote the intelligent and modern transformation of the construction industry, with a total investment of 37.4 billion yuan in signed projects [9] - The national strategy during the 14th Five-Year Plan period emphasizes the rapid development of smart construction and the application of advanced technologies and materials [9][10]

当前，自动驾驶发展进入深水区，干线物流因其场景相对规范、市场规模巨大，被公认为可能是最快实 现商业化的"黄金赛道"。 12月12日，旨在加速干线物流自动驾驶商业化落地的干线物流自动驾驶商业化路径研讨会暨四川省港投 集团干线物流自动驾驶"挑战赛"招募发布会在清华大学举办。该活动由四川省港航投资集团有限责任公 司（以下简称四川港投集团）、西部科学城智能网联汽车创新中心（以下简称西部智联）、清华大学智 能绿色车辆与交通全国重点实验室共同主办。 中国公路学会理事长翁孟勇会上表示，发展干线物流自动驾驶是解决行业结构性痛点的必由之路。目 前，在试验区、封闭场地开展试验的意义已经有限，应当在相对开放的场景中推动自动驾驶实践落地。 为深化战略布局与合作，四川港投经济技术研究有限公司与西部智联在会上签署战略合作协议，双方在 干线物流自动驾驶领域建立起紧密的生态合作伙伴关系。 清华大学车辆与运载学院教授、智能绿色车辆与交通全国重点实验室主任、西部科学城智能网联汽车创 新中心首席科学家李克强表示，交通系统智能化成为趋势，高速公路干线物流自动驾驶是技术进步和真 实需求共同驱动的成果，能带来巨大经济和社会效应。他认为，自动驾驶不是孤立 ...