Core Insights - Eli Lilly announced significant results from the Phase 3 EMBER-3 clinical trial of the oral estrogen receptor antagonist imlunestrant, showing a 38% reduction in the risk of disease progression or death in patients with ESR1 mutations compared to endocrine therapy [1][2] - The median progression-free survival (PFS) for imlunestrant was 5.5 months versus 3.8 months for endocrine therapy, with a hazard ratio (HR) of 0.62 [1] - The median overall survival (OS) was extended by 11.4 months, with imlunestrant showing 34.5 months compared to 23.1 months for the control group, achieving a HR of 0.60 [1] - In all patients, the combination of imlunestrant and abemaciclib reduced the risk of disease progression or death by 41%, with a trend towards improved overall survival and a delay in time to chemotherapy exceeding one year [1] Company and Industry Developments - The results were published in the Annals of Oncology and presented at the San Antonio Breast Cancer Symposium (SABCS) [2] - Eli Lilly's Executive Vice President and President of Oncology, Jake Van Naarden, emphasized the clinical benefits of imlunestrant in both monotherapy and combination therapy, reinforcing its position in the treatment landscape [2] - The company is encouraged by the potential of the all-oral combination treatment of imlunestrant and abemaciclib and has submitted relevant data to U.S. regulatory authorities for patients with ESR1 mutation metastatic breast cancer [2]

成本接近经济性拐点 从资源禀赋看，钠离子电池突出的优势在于其原材料的广泛性与稳定性。据了解，钠元素在地壳中的丰 度约为锂元素的1000倍，同时还广泛存在于海水中，获取成本与供应风险相对可控。与之形成鲜明对比 的是，锂资源分布相对集中，受地缘政治、资源开发节奏以及市场情绪影响较大，价格波动明显。 2020年至2024年，碳酸钠价格基本维持在每吨100至500美元区间，而碳酸锂价格则在每吨6000美元至 83000美元之间大幅波动，两者差距显著。这种长期存在的原材料价格差异，为钠离子电池在理论成本 结构上的"低起点"提供了重要支撑，也成为其被视为低成本技术路线的重要基础。 来源：中国能源报 国际可再生能源机构近日发布最新报告指出，钠离子电池在成本控制方面正展现出明显潜力，当前已降 至每千瓦时90美元至125美元区间，正逐步趋近于锂离子电池的75美元至105美元区间水平。预计随着产 业链逐步成熟、规模化生产加速推进，钠离子电池成本有望在未来进一步下降，最低可能降至每千瓦时 40美元左右。 在全球能源转型持续深化、对绿色低碳与供应链安全要求不断提高的背景下，钠离子电池能否借助成本 快速下降的窗口期实现规模化应用拓展， ...

来源：光明日报 【科学+】 编者按 全国科学技术名词审定委员会日前发布了"基于重大科技创新的新概念新术语规范化体系化"工作成果。 其中，"泛在操作系统""高性能制造""深部固体资源流态化开采""超级微创手术"4项体系化新名词，均 为我国科学家率先提出。它们萌发于重大科技创新的生动实践，是科学家在加快建设科技强国、实现高 水平科技自立自强的征程中，对标"构建汉语科技语言体系"，主动参与国际科技话语权竞争的积极尝 试。 它们将对科研工作，乃至日常生产、生活产生怎样的影响？听听科技大咖们怎么说—— 泛在操作系统 推动"万物互联"走向智能协同 梅宏 郭耀 人类正在进入一个"人机物"三元融合的万物智能互联时代。万物数字化、社会经济数字化转型，催生 了"计算无处不在而又无迹可寻"的泛在计算（ubiquitous computing）新场景。在此背景下，一种新型基 础软件形态——泛在操作系统应运而生。该系统秉承泛在计算思想，面向泛在化计算资源管理，支持泛 在应用开发运行，具有泛在感知、泛在互联、轻量计算、轻量认知、反馈控制、自然交互等新特点，标 志着操作系统从管理"单台计算设备"迈向管理"人机物多类资源及其融合"的新阶段。 ...

中金资本董事总经理沈圆江表示："荷声科技自成立以来，专注于突破高端超声核心技术，展现出显著 成长潜力，同时在新一代超声系统发展趋势中具备前瞻性布局。本轮Pre-A融资完成，是对其技术实力 和行业前景的积极认可。我们相信，在产业资源的协同下，荷声科技将稳步推进产品落地与规模化应 用，持续引领中国高端医疗超声创新发展。" 专注于微型片上超声模组与系统，荷声科技（Sonosilicon）依托面阵ASIC、硅基超声换能器与基于边缘 计算的超声AI，构建从芯片、模组到智能系统的自主技术链；作为国内唯一具备四维面阵超声成像芯 片自研能力、全球少数拥有片上超声闭环体系的创新主体，公司持续推动高端超声国产化，填补国内在 大规模面阵超声、四维心腔内超声（4D-ICE）、微型环阵血管内超声（R-IVUS）等关键领域的产业空 白，并以自主eMUTrix™有源面阵超声与柔性互联技术，积极布局可穿戴超声贴片与超声脑机接口等前 沿应用，面向全球提供新一代生命健康监测与医疗诊断解决方案。 阿斯利康国际业务拓展合作与战略投资副总裁陈冰表示："我们很高兴领投荷声科技本轮融资。随着半 导体与片上系统的融合加速，医疗影像正迈向芯片化、模块化与智能 ...

Core Viewpoint - Heilongjiang is leveraging its unique resources and strategic partnerships, particularly with Huawei, to drive digital transformation and innovation in artificial intelligence and computing power integration, positioning itself as a key player in China's digital economy [1][3]. Group 1: Digital Transformation as a Core Economic Engine - Heilongjiang has established AI innovation and computing power integration as the core engine for economic development during the 14th Five-Year Plan, driven by its inherent "seeking change" ethos [1]. - The province's confidence is rooted in its rich resource endowment, including a concentration of computing power demand and abundant electricity resources, making it an ideal hub for a new type of intelligent computing center [1]. - Heilongjiang boasts a strong educational foundation with institutions like Harbin Institute of Technology and Harbin Engineering University, providing a continuous supply of talent for AI and computing industries [1]. Group 2: Challenges and Shortcomings - Compared to coastal eastern regions, Heilongjiang's digital economy is relatively underdeveloped, with a weak industrial digitalization foundation and an existing "digital divide" [2]. - Traditional enterprises, especially SMEs, face significant challenges in transformation due to high technical barriers, substantial capital investment, and a lack of talent [2]. - There is a pressing need for continuous improvement in digital infrastructure, including computing power scheduling efficiency and data element circulation [2]. Group 3: Partnership with Huawei - Huawei has committed to deeply engage with Heilongjiang, integrating its technological expertise in computing, communication, energy, cloud, and AI to support the province's digital economy and high-quality urban development [3]. - The collaboration aims to provide a comprehensive suite of innovative technologies and extensive industrial ecosystem resources, tailored to Heilongjiang's unique advantages and strategic needs [3]. - Huawei's proposed solutions include stable green electricity for computing power through collaborative technologies and the establishment of resource pools for various industry applications [3]. Group 4: Industry Ecosystem Development - Huawei is facilitating Heilongjiang's digital transformation by establishing collaborative platforms, such as joint innovation labs with China Railway Harbin Bureau Group, focusing on standardizing solutions for the railway sector [4]. - The establishment of the "AI Empowering Digital Development Industry Alliance" signifies a new cooperative paradigm aimed at bridging the gap between technology research and industrial application [5]. - Huawei's initiatives are permeating various sectors, enhancing infrastructure intelligence and building a sustainable talent pipeline for long-term development [5]. Group 5: Practical Applications of Digital Transformation - The "Longzheng Zhishu" government model exemplifies successful digital governance, integrating over 400 billion pieces of data and significantly improving efficiency in local government operations [6]. - The logistics company Dada Zhiyun has transformed its operations into a comprehensive supply chain service provider by leveraging Huawei's technology to create an integrated logistics platform [6]. - The establishment of a modern industrial college in collaboration with Huawei is revolutionizing IT talent training, providing practical experience and skills aligned with industry needs [7]. Group 6: Conclusion - The partnership between Huawei and Heilongjiang represents a deep integration of technological empowerment and regional advantages, driving the revitalization of the Northeast and contributing to high-quality development in the digital economy [7].

Core Insights - The integration of computing power and electricity, termed "算电融合" (computing-electricity integration), is emerging as an innovative model that supports the green energy-driven digital economy, particularly benefiting the artificial intelligence (AI) industry [1][2][3] - The "算电融合" initiative aims to create a new infrastructure that combines energy flow, data flow, and value flow, enhancing the synergy between green electricity and intelligent computing [1][6] - The recent Huawei summit in Heilongjiang focused on promoting this integration and fostering collaboration among various industries to drive high-quality digital economic development in the region [2][5] Group 1: Industry Development - Heilongjiang is positioning itself as a leader in the integration of computing power and electricity, leveraging its energy-rich resources to accelerate economic growth in the digital era [1][6] - The establishment of the AI-enabled digital transformation industry alliance aims to bridge the gap between technology development and industrial application, facilitating the adoption of AI across various sectors [4][6] - Huawei's commitment to innovation in computing and energy sectors is expected to enhance the stability and efficiency of green electricity supply for computing needs, supporting the development of a new green intelligent computing center in Heilongjiang [7][8] Group 2: Strategic Initiatives - The national strategies "东数西算" (East Data West Computing) and "算电协同" (Computing-Electricity Collaboration) present significant opportunities for Heilongjiang as a demonstration province for computing-electricity integration [7] - The summit emphasized the importance of aligning computing power projects with green electricity supply, advocating for a coordinated approach to optimize energy and computing resources [6][7] - Future collaborations and project implementations are expected to unlock the potential of computing-electricity integration and AI, driving regional industrial upgrades and contributing to the high-quality development of Northeast China [8]

Core Viewpoint - MiniMax, a domestic large model enterprise, has received approval from the China Securities Regulatory Commission and passed the Hong Kong Stock Exchange hearing, planning to go public in January 2026, potentially becoming the fastest AI company from establishment to IPO globally [1] Company Overview - MiniMax was established in early 2022 and aims to be the "first global AGI stock" in the capital market [1] - The company is among the few in the first tier of full-modal models, showcasing industry-leading technical strength [1] Technology and Performance - The text model MiniMax M2 ranks in the top five globally and first among open-source models according to the Artificial Analysis evaluation [1] - The video model Hailuo 02 series has set records in global video model performance-cost metrics, ranking in the top three on multiple lists [1] - The speech model Speech02 series has surpassed OpenAI in international assessments, achieving the top position globally [1] Commercialization and Market Reach - MiniMax has served over 212 million users across more than 200 countries and regions, with over 100,000 enterprise clients [1] - The company achieves sustainable profitability through paid subscriptions and model calls, leading in commercialization performance [1] Investment and Market Potential - Backed by top-tier institutions such as Alibaba, Tencent, and Hillhouse Capital, MiniMax's upcoming IPO will fill a gap in the Hong Kong AGI sector [1] - The global AI market is expected to grow 25 times over the next decade, presenting a rare opportunity for investors to participate in a technological revolution [1] - MiniMax is anticipated to lead the Hong Kong IPO market in 2026 [1]

Core Viewpoint - The data center industry is undergoing a profound transformation, evolving from a mere physical space for data storage and computation to a "computing power center" essential for AI model training and algorithm iteration [1] Group 1: Industry Challenges and Opportunities - The primary challenge facing the IDC industry is not merely technical bottlenecks but a shift in cognitive understanding, moving from "what I can do" to "what I need to do in the future" [3][11] - The demand for computing power in the AI era is characterized by diversification, high elasticity, and rapid iteration, with hardware and algorithm cycles shortening from five to six years to two to three years, and potentially to six months in the future [5] Group 2: Strategic Directions - The future computing power centers must embody compatibility and foresight, as traditional data centers lacking these traits are at risk of obsolescence [4] - The company advocates for a "toolbox" approach, storing a series of compatible technologies that can be flexibly combined to meet varying needs and developmental stages [6] Group 3: Lifecycle and Sustainability - The industry is currently focused on PUE (Power Usage Effectiveness) and WUE (Water Usage Effectiveness), but a more comprehensive view of the full lifecycle resource consumption is necessary, from raw material extraction to end-of-life disposal [7][8] - The company has developed models to analyze the true value of energy-saving measures, emphasizing the importance of optimizing applications and reducing energy conversion losses [8] Group 4: Cooling Technologies - Liquid cooling technology is seen as a potential solution for high-density heat dissipation, but its current market share is only about 15%, with mainstream applications still concentrated in the 10-20 kW range [10] - The company acknowledges that the development of high-density liquid cooling is still in the exploratory phase, requiring extensive application cases and data to validate its effectiveness [11]

戚发轫院士深情回顾了航天生涯中的"三件事"：第一件事是响应毛主席的号召，参与第一颗人造地球卫 星"东方红一号"任务；第二件事是上世纪七八十年代参与"331工程"，把中国第一颗通信卫星"东方红二 号"送上太空；第三件事是参与神舟五号飞船任务，让中国成为世界上第三个具有载人航天能力的国 家。 来源：科技日报 ◎ 科技日报记者 付毅飞 记者从中国航天科技集团五院获悉，12月17日，"戚发轫星"命名仪式暨太空探索开发学术报告会在该院 举行。 仪式现场宣读并颁发了"戚发轫星"国际命名公报及命名证书，由中国科学院紫金山天文台发现的、国际 编号336877号的小行星，经天文学联合会批准，被正式命名为"戚发轫星"。 戚发轫，男，1933年4月生于辽宁省复县（现辽宁省大连市瓦房店市），中国工程院院士、神舟飞船首 任总设计师、国际宇航科学院院士，现任中国航天科技集团五院技术顾问。 来源：科技日报 文中图片来自中国航天科技集团五院 ...

Core Viewpoint - The discovery of a new mineral named Jinxiuite (金秀矿) by the China Geological Survey team highlights the significance of the Longhua nickel-cobalt deposit in Guangxi, which is characterized by high-grade hydrothermal nickel-cobalt mineralization and is crucial for China's resource strategy in nickel and cobalt [1][3][4] Group 1: Mineral Discovery - The new mineral Jinxiuite has been officially approved with the international designation IMA2025-059, and its chemical formula is Ni₁₈Bi₂SbAsS₁₆ [3] - Jinxiuite is the second new mineral discovered in the Longhua nickel-cobalt deposit, following the discovery of Guixiangite (贵祥矿) [3] Group 2: Geological Significance - The Longhua nickel-cobalt deposit is characterized by high-grade vein-type mineralization, primarily composed of nickel-cobalt arsenic sulfides, indicating a complex formation process involving multiple phases of magmatic hydrothermal activity [3][4] - The discovery of Jinxiuite and Guixiangite suggests that the mineral composition is influenced by early mineralization processes, with later stages introducing more cobalt-bearing minerals and increasing concentrations of bismuth and antimony [3] Group 3: Industry Implications - Nickel and cobalt are critical minerals for China, with applications in aerospace, chemical, mechanical manufacturing, and home appliances, particularly as key components in lithium-ion batteries [4] - The discovery of new mineral resources is significant for addressing China's reliance on imported cobalt, which has been a long-standing issue due to the scarcity of domestic resources [4]