合成生物学与绿色生物制造
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第一波大咖嘉宾揭晓!2025(第五届)非粮生物质高值化利用论坛将于11月杭州启程
合成生物学与绿色生物制造· 2025-10-16 10:08
Core Viewpoint - The NFUCon 2025 forum will focus on the innovative research and commercial feasibility in the non-grain biomass sector, aiming to promote large-scale applications of non-grain biomass and support carbon neutrality goals [2]. Group 1: Event Overview - The NFUCon 2025 will be held from November 27 to 29, 2025, in Hangzhou, Zhejiang, under the theme "Top Talent Gathering, Industry Symbiosis" [2]. - The forum will invite representatives from government, enterprises, and experts to discuss key strategic directions such as biomass green pretreatment, non-grain sugars, biomass-based chemicals and materials, and biomass energy [2]. Group 2: Organizing Institutions - The forum is organized by Ningbo Detai Zhongyan Information Technology Co., Ltd. (DT New Materials) and the National Key Laboratory of Biomass Transportation Fuel Technology [3]. - Key figures include Zhu Jin, Li Zhenglong, and Zhang Xinghong, who hold significant positions in relevant research institutions and laboratories [3][4][5]. Group 3: Guest Speakers - Notable speakers include Zhu Jin, who has achieved multiple industrialization results in heat-resistant polylactic acid foaming materials and other biomass materials [4]. - Li Zhenglong focuses on the conversion and utilization of low-carbon resources, particularly in renewable aviation fuel and biomass separation technologies [5]. - Zhang Xinghong is involved in polymer synthesis research and CO2-based polycarbonate technology [6]. Group 4: Forum Agenda - The forum will feature various activities, including a youth forum on non-grain biomass, a sustainable aviation fuel industry exchange, and thematic discussions on biomass chemicals and energy [15][16]. - A technology achievement display area will be set up to showcase 50 innovative projects with commercial potential in the biomass utilization field [17]. Group 5: Laboratory Focus - The National Key Laboratory of Biomass Transportation Fuel Technology focuses on four core areas: fiber ethanol technology, bio-aviation fuel technology, CO2-based polycarbonate technology, and biofuel evaluation standards [22].
美尚洁生物最新融资!推动其重组人源化胶原蛋白产品的临床转化,实现了大规模的合成生物学发酵提取!
合成生物学与绿色生物制造· 2025-10-15 02:12
/生物制造产业社群/ 让上下游聚在一起, 未来食农、绿色化工、大健康、美妆个护 等产业同行❤️↓ 资本事件 | 美尚洁生物 【SynBioCon】 获 悉 ,近日,江苏美尚洁生物科技有限公司 (以下简称 "美尚洁生物")宣布已 成功完成数千万人民币的新一轮 A+ 轮 融资。 本轮募集资金将用于进一步加速公司在基因工程合成生物领域的研发投入, 推动其重组人源化胶原 蛋白产品的临床转化与市场拓展,并持续优化其技术平台 ,计划在宜兴落地新的三类器械生产管线 。 此外, 本轮跟投还有数千万的跟投额度,其它数家投资机构仍在积极跟进中。 自2018年成立以来,美尚洁生物始终深耕于基因工程合成生物科技领域,尤其在 重组人源化胶原蛋 白产品的研发及医疗应用 方面取得了突破性进展。此次融资的成功,不仅是对我们现有成果和未来 潜力的肯定,更是对我们坚持技术创新的有力证明。我们将以此为契机,进一步加大研发力度,加快 产品上市步伐,为医疗健康领域带来更安全、更有效的解决方案。" 美尚洁生物的核心竞争力在于其创新性的技术平台。 作为 国内首家基于 AI 技术进行重组融合蛋白 研发 的公司, 已成功运用 AI模型技术完成了序列片段的多样 ...
第一波大咖嘉宾揭晓!2025(第五届)非粮生物质高值化利用论坛将于11月杭州启程
合成生物学与绿色生物制造· 2025-10-15 02:12
Core Viewpoint - The NFUCon 2025 forum will focus on the innovative research achievements and commercial feasibility in the non-grain biomass sector, aiming to promote large-scale applications of non-grain biomass and support carbon neutrality goals [2]. Group 1: Organizing Institutions - The forum is organized by Ningbo Detai Zhongyan Information Technology Co., Ltd. and the National Key Laboratory of Bio-based Transportation Fuel Technology [3]. - Key figures include Zhu Jin, Li Zhenglong, and Zhang Xinghong, who hold significant positions in relevant research institutions and laboratories [3][4][5]. Group 2: Guest Highlights - Zhu Jin has achieved multiple industrialization results in heat-resistant polylactic acid foaming materials and other bio-based materials [4]. - Li Zhenglong focuses on the conversion and utilization of low-carbon resources, particularly in renewable aviation fuel and C1 catalysis [5]. - Zhang Xinghong is involved in polymer synthesis research and CO2-based polycarbonate technology [6]. Group 3: Forum Agenda - The forum will feature various activities, including a youth forum and discussions on sustainable aviation fuel [16]. - The main sessions will cover topics such as biomass green pretreatment, non-grain sugars, bio-based chemicals, and materials [16]. - A technology achievement display area will be set up to showcase 50 innovative projects with commercial potential [17]. Group 4: Laboratory Overview - The National Key Laboratory of Bio-based Transportation Fuel Technology focuses on four core areas: fiber ethanol technology, bio-aviation fuel technology, CO2-based polycarbonate technology, and biofuel evaluation standards [22].
Science子刊 | 浙江大学陈卫教授团队在合成生物学领域取得重要进展
合成生物学与绿色生物制造· 2025-10-15 02:12
Core Viewpoint - The article discusses the advancements in glycosyltransferase engineering for the efficient glycosylation of flavonoids, highlighting the potential applications in health and wellness products, as well as in the fields of agriculture and biomedicine [5][11]. Summary by Sections Glycosylation of Flavonoids - Flavonoids are important plant secondary metabolites with significant biological activities used in disease prevention and treatment [3]. - The glycosylation of flavonoids is catalyzed by plant UDP-glycosyltransferases (UGTs), which is a green and economical method compared to traditional chemical synthesis [3][4]. Research Findings - The study identified a rare glycosyltransferase, UGT75AJ2, capable of catalyzing the glycosylation at C-3' and C-7 hydroxyl positions of flavonoids, leading to the directed synthesis of bioactive flavonoid glycosides [5][6]. - The research demonstrated that glycosylation at these positions enhances antioxidant and blood sugar-lowering activities [4]. Engineering Strategies - A custom FRISM strategy was developed for the rational design of UGTs, resulting in a quadruple mutant (Mut4-1) of UGT75AJ2 with 128 times the catalytic activity of the wild type [7]. - The strategy was also successfully applied to other glycosyltransferases, validating its effectiveness and versatility [7][8]. Implications and Applications - The study provides a new paradigm for enhancing the activity, donor promiscuity, and regioselectivity of plant glycosyltransferases, which is crucial for the biosynthesis of high-value flavonoid glycosides [11]. - This research integrates multiple disciplines, including food science, synthetic biology, artificial intelligence, and pharmacology, contributing to the development of health products with medicinal value [11].
最高800万!上海发布:重点支持特色种源、农业生物制造、现代设施农业等新赛道
合成生物学与绿色生物制造· 2025-10-13 14:38
Core Viewpoint - The article discusses the recent policy developments in Shanghai aimed at promoting agricultural technology innovation, particularly in the fields of agricultural biotechnology and modern facility agriculture, to enhance the competitiveness and sustainability of urban agriculture [2][3]. Summary by Sections Policy Framework - The Shanghai Municipal Agricultural and Rural Committee, in collaboration with the Finance Bureau, has established guidelines for managing agricultural science and technology innovation projects and funding [2][3]. Funding Support - The policy emphasizes the importance of ensuring project funding safety while stimulating technological innovation, with dedicated funding for various projects [4]. - Key technology projects can receive up to 4 million yuan over a 3 to 5-year period, while important innovation projects can receive up to 2 million yuan over 2 to 3 years, with flexibility for longer projects [5]. Application and Industry Enhancement - Application scenario projects aim to create a comprehensive agricultural technology application ecosystem, with funding up to 3 million yuan for a 2 to 3-year implementation period [5]. - Industry enhancement projects focus on promoting advanced agricultural varieties, technologies, and models, with funding up to 8 million yuan for a maximum of 3 years [5]. Collaborative Breeding and Talent Development - Joint breeding projects support collaboration between seed companies and research institutions, with annual funding up to 500,000 yuan for a maximum of 5 years [6]. - The policy also includes support for cultivating young agricultural technology talents, with funding up to 20,000 yuan per project [6].
第一波大咖嘉宾揭晓!2025(第五届)非粮生物质高值化利用论坛将于11月杭州启程
合成生物学与绿色生物制造· 2025-10-13 14:38
Core Viewpoint - The NFUCon 2025 forum will focus on the innovative research and commercial feasibility in the non-grain biomass sector, aiming to promote large-scale applications of non-grain biomass and support carbon neutrality goals [2]. Group 1: Organizing Institutions - The forum is organized by Ningbo Detai Zhongyan Information Technology Co., Ltd. and the National Key Laboratory of Bio-based Transportation Fuel Technology [3]. - Key figures include Zhu Jin, Li Zhenglong, and Zhang Xinghong, who hold significant positions in relevant research institutions and laboratories [3][4][5]. Group 2: Guest Highlights - Zhu Jin has achieved multiple industrialization results in heat-resistant polylactic acid foaming materials and other bio-based materials [4]. - Li Zhenglong focuses on the conversion of low-carbon resources and has made advancements in renewable aviation fuel and C1 catalysis [5]. - Zhang Xinghong is involved in polymer synthesis research and CO2-based polycarbonate technology [6]. Group 3: Forum Agenda - The forum will feature various activities including a youth forum, discussions on bio-based chemicals and materials, and a sustainable aviation fuel industry exchange [15][16]. - The agenda includes specialized topics on biomass green pretreatment, non-grain sugars, and bio-based energy sources such as methanol and sustainable aviation fuel [15]. Group 4: Technology Showcase - The forum will host a technology showcase to connect 50 innovative projects in biomass utilization with commercial potential [17]. - This initiative aims to facilitate industry-academia-research collaboration and promote the transfer of quality results [17]. Group 5: Laboratory Overview - The National Key Laboratory of Bio-based Transportation Fuel Technology focuses on four core areas: fiber ethanol technology, bio-aviation fuel development, CO2-based polycarbonate technology, and biofuel evaluation standards [22].
李开复,在成都投了一家 “0卡糖” 合成生物企业
合成生物学与绿色生物制造· 2025-10-13 14:38
Core Viewpoint - The article highlights the investment in Sichuan Yingjia Hesheng Technology Co., Ltd., a major producer of steviol glycosides, emphasizing its role in the synthetic biology sector and its potential for growth in various markets, particularly in the U.S. and Southeast Asia [2][5]. Company Overview - Yingjia Hesheng, established in 2015, focuses on using synthetic biology to manufacture natural products, with applications in pharmaceuticals, health care, and food and beverage industries [4]. - It is the largest supplier of steviol glycosides in China and one of only three companies globally to receive GRAS certification for its rare steviol glycoside, Rebaudioside I [3][5]. Market Position - Since 2019, Yingjia Hesheng has successfully entered the U.S. market and is part of the supply chains of several international food and beverage companies, with increasing sales in the UK and Southeast Asia [5]. - The company is also planning to expand into emerging markets such as Japan and South Korea [5]. Product Line - In addition to steviol glycosides, Yingjia Hesheng's product portfolio includes Coenzyme Q10, new types of steviol glycosides, β-Nicotinamide Mononucleotide (NMN), and vanillin, covering multiple sectors including pharmaceuticals and health supplements [5]. Industry Development - Chengdu is positioning itself as a significant hub for synthetic biology and biomanufacturing, with over 300 biopharmaceutical projects introduced by the end of 2024, and a total industry scale exceeding 350 billion yuan [9][10]. - The local government has implemented policies to support the development of synthetic biology, recognizing its potential to replace traditional chemical processes and enhance the local economy [10][11].
总投资145.3亿:重庆市签约32个项目,生物制造领域聚焦中试平台建设
合成生物学与绿色生物制造· 2025-10-10 07:41
以下文章来源于动脉生物制造 ,作者武瑛港 动脉生物制造 . 动脉网(www.vbdata.cn)聚焦于技术驱动下生命健康领域产业创新和变革的报道与研究。 /生物制造产业社群/ 让上下游聚在一起, 未来食农、绿色化工、大健康、美妆个护 等产业同行❤️↓ 全球政策进展 | 重庆市 【SynBioCon】 获 悉, 9 月 23 日,根据重庆日报信息,重庆市璧山区举行招商引资项目集中签约 活动暨产业创新综合体集群培育启动大会, 32 个总投资达 145.3 亿元 的项目完成签约。 项目涵盖 生物制造、生物医药、智能装备 、新一代电子信息制造、智能网联新能源汽车、现代物流等 多个领域,同步启动多个产业创新综合体共建合作。 其中在生物制造领域,璧山区签约了 重庆生物制造产业中试平台项目 ,聚焦智能化生物发酵等生物制造关 键技术领域,计划打造集"工艺优化、中试验证、数据集成、智能制造"功能于一体的 国家级生物制造中试 平台 ,致力于成为具有全国辨识度的 生物制造产业"西南中心"。 据了解, 2025 年 4 月,重庆市政府发布的《关于做好 2025 年市级重点项目实施有关工作的通知》显示, 2025 年市级重点项目包括开 ...
2025(第五届)非粮生物质高值化利用论坛将于11月杭州启程!
合成生物学与绿色生物制造· 2025-10-10 07:41
Core Insights - The article discusses the upcoming "2025 Non-Grain Biomass High-Value Utilization Forum" scheduled for November 27-29, 2025, in Hangzhou, Zhejiang, focusing on the commercialization and technological advancements in non-grain biomass resources [2][3] - The forum aims to explore key areas such as biomass green pretreatment, non-grain sugars, biomass-based chemicals and materials, and biomass energy, contributing to the achievement of carbon neutrality goals [2][4] Forum Organization - The forum is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and the National Key Laboratory of Biomass Transport Fuel Technology, with prominent figures from academia leading the event [3][4] - Key figures include Zhu Jin, Li Zhenglong, and Zhang Xinghong, who are experts in biomass materials and biofuels [3][4] Forum Agenda - The forum will feature various specialized sessions, including topics on biomass green pretreatment, non-grain sugars, biomass-based chemicals, and biomass energy [5][6] - Specific sessions will cover technologies such as steam explosion, industrial fermentation strains, and the development of sustainable aviation fuel (SAF) [6][10] Special Activities - A special activity titled "Technology Achievement Display and Docking" will be held to promote the commercialization of innovative projects in the biomass utilization field, with 50 selected projects to be showcased [9][10] Industry Participation - The forum will attract a diverse range of participants, including biomass energy and chemical developers, academic researchers, and solution providers in biomass processing technologies [14][17] - The event aims to facilitate collaboration between industry, academia, and government organizations to advance the biomass sector [14][17]
首创!我国科学家实现海水中二氧化碳变生物塑料,可拓展多种生物制造产品
合成生物学与绿色生物制造· 2025-10-10 07:41
【SynBioCon】 获 悉 , 10月6日, 中国科学院深圳先进技术研究院定量合成生物学全国重点实 验室、合成生物学研究所高翔团队联合电子科技大学夏川团队 ,首次提出并验证了一种 基于"电催 化+生物催化"耦合策略的"人工海洋碳循环系统" ,相关成果发表在国际学术期刊《自然·催化》。 该系统可捕集天然海水中的CO₂,并转化为可直接进入生物制造的中间体,再进一步升级为 多类高 价值化学品与材料 。该研究以 可降解塑料单体 为示范案例,有望为燃料、医药与食品配料等更广 谱产品提供生物制造平台。 /生物制造产业社群/ 让上下游聚在一起, 未来食农、绿色化工、大健康、美妆个护 等产业同行❤️↓ SynBio团队 | 深圳先 进院 高翔、电子科大夏川 海洋作为地球上最大的天然"碳库",每年吸收逾四分之一人为排放的二氧化碳,有效减缓了全球气 候变暖。然而,海水持续吸收二氧化碳引发的海洋酸化,对海洋生态平衡构成了严重威胁。如何把这 部分已进入海洋的碳,转化为人类可利用的资源,减缓海水酸化,是实现"蓝色经济"与"双碳"目标 所必须面对的共同命题。 项目负责人夏川教授指出,该成果紧密围绕国家"双碳"目标和蓝色经济发展需求, ...