/DT非粮生物质利用交流群/ 让专业的人聚在一起, 非粮生物质利用/三素分离/生物质能源/生物炼制等产业同行❤️↓ 非粮生物质利用 | 非粮糖 【SynBioCon】 获 悉， 近日， 山东大学微生物改造技术全国重点实验室 钟耀华教授课题组 在纤维 素酶 生产及 木质纤维素糖制备方面取得重要进展。 挖掘出具有超高β-葡萄糖苷酶活性的里氏木霉工程菌株SCB18 ， 成功建立了底物负荷为35%的玉米 秸秆高固糖 化体系 ，获得了 144.5 g/L的木质纤维素糖 ，同时成功将 纤维素酶 用量降低到了 3 FP U/g DM 。 相关研究成果以"Achieving high-concentration lignocellulosic sugars by using theTrichod erma reesei strain with high β-glucosidase activity for inducersynthesis and cellulase pr oduction"为题发表于工程技术领域国际知名期刊《Chemical Engineering Journal》（ IF 13.2 ）。 木质纤维素生物质 ...

尽管 苯乙酮及其衍生物的生物学功能已被充分报道 ， 但其 生物合成途径 仍 有待阐明 。 虽 有研究指出 苯乙酮可能通过 β-氧化途径 生成 ， 也有研究 通过同位素标记证实 苯丙氨酸代谢产生的 肉桂酸 是苯乙酮 的合成 前体 ， 然而该 合成途径中 的 具体酶 促反应步骤 和涉及的酶尚不明确 。 【SynBioCon】 获 悉， 2025年 9 月 5 日， 西北农林科技大学 徐凌飞 教授带领的梨研究团队 在 Nature Plants 在 线 发 表 了 题 为 " Naturally impaired side-chain shortening of aromatic 3- ketoacyl-CoAs reveals the biosynthetic pathway of plant acetophenones "的研究论文 （ 梨领域 首篇 ） 。该研究 以梨为材料，揭示了苯乙酮类化合物的 完整 生物合成途 SynBio团队 | 西北农林科大徐凌飞教授、苯乙酮 苯乙酮及其衍生物 在 植物 界 和微生物 界中分布 广泛 ， 具有多样的生物学功能。 在植物界， 苯乙酮 （acet ophenone ） 是 ...

助力生物基和生物制造产业高质量发展！ DT产业研究院 特推出 《全球生物基产业月度报告》 、 《全球生物制造产业月报》 系列。 5分钟，掌握全球生物基和生物制造产业最新情报和大厂动态，洞悉趋势，发现商机！最新8月期出炉，欢迎行业上下游同仁 免费领取 ！ 领取方式① ：扫码下方二维码，提交信息后，即可下载报告（2份报告可一同下载）； 领取方式② ： www.bio-basedlink.net ，或点击文末 → 阅读原文 ↓ 领取方式③ ：如果您是DT会员，请联系DT助手领取； ↓↓↓ 《生物基产业月度报告》 2025年8月（总第29期） 学 口T 额则退 目录 | 1. 政策发布 | | --- | | 1.1 回内篇 - | | 1.2 国外篇 | | 2. 行业动态 | | 2.1 全球生物基化学品行业动态 . | | 2.2 全球生物基材料行业动态 | | 2.3 全球生物基复合材料行业动态 | | 2.4 全球生物基制品行业动态 | | 2.5 全球生物质能源行业功态 | | 3. 资本事件 | | 3.1 国内简单 | | 3 2 国外第 2014 | | 4、科研战屡 1111年11月11日11月1 ...

从产业生态搭建来看， 微康益生菌拥有亚洲最大的益生菌菌种研发智能制造基地 ，产品更是获评拜耳制药全球最佳供应商；还成功孵化 益一科技、康科 生物、修喵修勾科技、玖明医疗等企业 ，覆盖医疗健康、膳食营养、宠物健康等细分领域，有效补全鼓楼合成生物产业链条。 SynBio团队 | 黄和院士 【SynBioCon】 获 悉， 近 日，鼓楼区政府与南京师范大学共建的 智能生物制造创新中心 启动仪 式在南京幕府智谷成功举办。 中心以合成生物学底层技术为核心，打造"1+1+N"创新模式，既依托南师大科研平台攻克核心技术，又联动企业推动成果落地，真正破解 "实验室突破 难转化为产业产品"的痛点 。 值得关注的是， 中国工程院院士、 南京师 范大学副校长黄和将担任智能生物制造创新中心管委会主任 。他将带领团队聚焦生物制造前沿领域，依托新 科学与新技术，推动创新中心打造成为合成生物学科研高地，为生命健康产业集群发展提供有力支撑。 仪式现场，黄和院士还为 微康益生菌 、纽邦生物、迪必尔生物工程、北极光等 企业负责人颁发智能生物制造创新中心产业顾问聘书。 此次活动签约的海尔生物、德悦普惠医疗、量准科技等项目，进一步覆盖 细胞库建设 ...

非粮生物质论坛 | 2025论坛官宣 近年，国家已发布一系列关于非粮生物基材料创新发展的方案，致力于打造基于大宗农作物秸秆、竹 子等非粮生物质资源利用的生物质能源和生物基材料体系。 非粮生物质利用产业未来 3-5年的发展 趋势？可商业化的路径？有哪些值得关注的技术团队和企业？从产业链角度和技术角度的挑战和解决 方案？ 一系列问题待剖析，一系列的产业机会也正被挖掘。 DT新材料旗下 【 生物基能源与材料】长期致力于生物基和生物制造产业的科技服务平台，拥有 5 万多 产业上下游数据， 是行业最重要的资源和信息枢纽之一 。 DT新材料 将 联合 生物基运输燃料技术全国重点实验室 将于 202 5 年 1 1 月 27-29 日 在 浙江 ·杭州 举办 " 202 5 （第 五 届）非粮生物质高值化利用论坛 （ NFUCon 2025 ） "，将邀约业 界上下游代表性企业与专家，探讨生物质绿色预处理、非粮糖、生物质基化学品和材料、生物质能 （甲醇、燃料乙醇、生物沼气、可持续航空燃料（ SAF））等重要方向，共同推动非粮生物质大规 模应用，助力实现双碳目标。 01 组织机构 / NFUCon 2025 主办单位 ： 宁 ...

Core Viewpoint - The article emphasizes the importance of industrial biotechnology in supporting China's sustainable development and innovation in the bio-economy, focusing on key technologies and research areas that can replace fossil resources with renewable carbon resources and enhance industrial processes through modern biotechnology [5][20]. Group 1: Research Focus - The research institute focuses on three strategic themes: replacing fossil resources with renewable carbon resources, using clean biological processing instead of traditional chemical methods, and enhancing industrial levels through modern biotechnology [5]. - Key research areas include industrial protein science and biocatalysis engineering, synthetic biology and microbial manufacturing engineering, and biological systems and bioprocess engineering [5]. Group 2: Team Introduction - Zhang Yiheng, a prominent researcher and doctoral supervisor, leads the Low Carbon Synthesis Engineering Biology National Key Laboratory and has made significant contributions to the field, including the establishment of the in vitro BioTransformation (ivBT) engineering technology system [6]. - Zhang Yuzhen, another researcher, has developed microfluidic technologies for quantitative studies of microbial populations and is working on high-throughput identification techniques for important industrial enzymes [7][8]. Group 3: Recruitment Information - The institute is seeking to hire 2-3 postdoctoral research assistants and 1-2 assistant researchers, with a focus on candidates holding doctoral degrees in microbiology, molecular biology, or enzyme engineering [9][10]. - Competitive salaries and benefits are offered, including social insurance, housing funds, and opportunities for professional development and overseas visits [11][12]. Group 4: Career Development - Postdoctoral researchers can apply for permanent positions with competitive salaries and development opportunities, including potential advancement to senior technical roles based on their research achievements [13][14]. Group 5: Upcoming Events - The article mentions an upcoming forum on non-grain biomass high-value utilization, scheduled for January 27-29, 2025, in Hangzhou, focusing on clean pretreatment of biomass and commercialization of bio-based materials and fuels [20].

项目进展 | 肆芃科技 【SynBioCon】 获 悉， 近日，肆芃科技在如皋（江苏南通）举办了 千吨级合成生物 柔性生产线 投产仪式 ，国投创合、本草资本、上海国投孚腾资 本、如皋科创投等股东代表及上海交通大学、如皋市及交大菡源资产等有关领导参与投产仪式。 加入→ 生物制造产业社群 开发 一碳碳源，肆芃科技聚焦 大宗生物基材料单体产品 4 月 21 日，肆芃科技宣布和中国科学院天津工业生物技术研究所达成合作，双方 将 以甲醇为原料开发大宗生物基材料单体产品 ，突破传统生物制造对 粮食碳源的依赖，并推动" 一碳生物制造 "的工业化落地。 针对此次合作，陶飞表示基于各自定位和战略发展方向的天然契合。天津工生所在低碳合成生物学等领域具有深厚的技术储备； 肆芃一代碳源的生物基 产品正在推进商业化，二代非粮技术也已成熟并处于工程化和产业化阶段 ，随着对三代技术的布局，双方在目标一致、志同道合的基础上进行合作，旨 在共同推进新技术的研发和应用。 点击阅读： "甲醇生物制造"大爆发？肆芃科技联手天工所攻关大宗生物基材料单体产品！ 说明： 本文部分素材来自肆芃科技 。由作者 重新编写，系作者个人观点，本平台发布仅为了传达一 ...

Core Viewpoint - The article discusses the recent legislative measures taken by Shenzhen to promote the synthetic biology industry, which is considered a new "golden track" in the context of the third biotechnology revolution. The new regulations aim to support innovation and development in this emerging sector, establishing a comprehensive service support system for synthetic biology enterprises [2][3]. Summary by Sections Legislative Framework - Shenzhen has passed the "Regulations on Promoting the Innovative Development of the Synthetic Biology Industry," which will take effect on October 1. This legislation is a pioneering effort in the field of industrial promotion and aims to address development bottlenecks in the synthetic biology sector [2][3]. Industry Support and Ecosystem - The regulations outline a full-chain service support system for synthetic biology, emphasizing the importance of source innovation for technology transfer. Approximately 40% of new synthetic biology enterprises in China have been established in Shenzhen over the past three years [4]. Product Market Entry - The regulations include measures to shorten the product market entry cycle for synthetic biology products, addressing the challenges of lengthy approval processes. This includes exploring new models for evaluation and technical institutions, as well as promoting the market demand for synthetic biology products through curated lists and procurement facilitation [6][7]. Financial and Spatial Support - The regulations reinforce the need for spatial and financial support for the synthetic biology industry. They prioritize land supply for enterprises and encourage financial institutions to lower financing costs for startups in this sector. Additionally, there are efforts to streamline approval processes and enhance the regulatory environment for synthetic biology enterprises [7].

Core Viewpoint - The article highlights the launch of the Zhejiang Zhenyuan Biological Industrialization Base, emphasizing its significance in the synthetic biology sector and its role in promoting high-quality economic development in Shaoxing [3][5]. Company Progress - Zhejiang Zhenyuan officially inaugurated its biological industrialization base on August 30, marking a key milestone in the development of synthetic biology and the production of high-end amino acids [3][5]. - The base is the first in China to feature a thousand-ton-level industrialization facility for the biosynthesis of histidine, showcasing advanced synthetic biology and fermentation engineering technologies [5][6]. - The project has received recognition as a major industrial project in Zhejiang and is part of the national green low-carbon advanced technology demonstration projects [5][6]. Financial Performance - In the first half of 2025, Zhejiang Zhenyuan reported a revenue of 1.283 billion yuan, a decrease of 34.49% year-on-year, while net profit attributable to shareholders increased by 29.27% to 56.26 million yuan [6][7]. - The company’s net profit, excluding non-recurring gains and losses, was 30.12 million yuan, down 20.32% compared to the previous year [6][7]. - The company’s total assets decreased by 13.55% to approximately 2.955 billion yuan, while net assets attributable to shareholders increased by 2.62% [7]. Industry Context - The synthetic biology sector is recognized as a core component of the "third biological technology revolution," with significant support from local government policies and funding exceeding 10 billion yuan [5][6]. - The base aims to replace traditional high-pollution and high-energy consumption processes with green technologies, contributing to the development of a sustainable industrial ecosystem [6][8]. - The project aligns with national strategies for the innovation and development of non-grain biomass materials, focusing on clean energy and material systems [10].

Core Viewpoint - The article discusses recent advancements in starch modification through the research conducted by the Tianjin Institute of Industrial Biotechnology, focusing on the enzyme Amylomaltase (AM) and its potential applications in addressing food security and carbon neutrality [5][6]. Group 1: Research Findings - The research team utilized large-scale molecular simulations and quantum mechanics/molecular mechanics (QM/MM) calculations to reveal the complete catalytic cycle of AM, identifying the rate-limiting steps in cycloamyloses (CA) synthesis [6][7]. - The study demonstrated that by strategically adjusting the polysaccharide chain transfer steps, several active mutant variants were obtained, enhancing enzyme performance primarily through reduced substrate transfer affinity [6][7]. - Mass spectrometry confirmed the generation of cycloamyloses with degrees of polymerization ranging from 22 to 61, validating theoretical predictions [6][7]. Group 2: Industrial Implications - The research provides a systematic molecular-level understanding of the biosynthesis process of CA, offering a clear engineering blueprint for the AM family, which could lead to more efficient and specific glycosyltransferases [6][7]. - The findings are significant for the industrial application of starch modification, contributing to the development of biobased materials and energy systems utilizing non-grain resources [9][11]. Group 3: Support and Collaboration - The research was supported by the Chinese Academy of Sciences' strategic pilot technology projects and the Tianjin Synthetic Biology Technology Innovation Capability Enhancement Action [7]. - Collaborations included contributions from various institutions, highlighting the interdisciplinary nature of the research [7].