Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through initiatives like green manufacturing and intelligent manufacturing [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan, discussing innovative technologies and products that will sustain the industry's vitality [1]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and supported by various academic and industry institutions, including Peking University and the China Society of Biotechnology [2]. Group 3: Highlights of the Conference - Key highlights include forums and closed-door discussions on biomanufacturing trends, youth innovation technology sharing, and over 100 financing project roadshows to discover new cooperation opportunities [5]. - The event will gather leading enterprises, top universities, investment institutions, and industry stakeholders to foster collaboration [5]. Group 4: Agenda and Activities - The first day features a closed-door seminar focusing on the development trends and growth points of biomanufacturing, inviting 30 industry leaders and experts for in-depth discussions [9]. - The second and third days will include a macro forum on biomanufacturing, specialized sessions on green chemicals, AI in biomanufacturing, future food and agriculture, and beauty raw materials [13][15][18]. Group 5: Specialized Topics - Specialized discussions will cover topics such as the development of bio-based chemicals, AI applications in biomanufacturing, and the use of non-grain carbon sources for bioconversion [16][17]. - The conference will also address the synthesis of high-value food ingredients and the role of biotechnology in health and beauty products [20].

Core Viewpoint - Sieman Technology is an innovative company focused on providing high-quality biological culture solutions for the life sciences sector, aiming to enhance research efficiency and accelerate product market entry [10]. Company Overview - Sieman Technology specializes in high-quality biological culture solutions for research institutions, biopharmaceuticals, and biotechnology companies [10]. - The company emphasizes the importance of biological culture and aims to provide stable and reliable biological culture instruments [10]. Product Introduction - **Biological Culture Shaker EM-10**: A monitoring device for biological culture processes, addressing common issues such as unstable results and high failure rates in continuous operation [11]. - **AS-1000 High-Temperature Online Optical Dissolved Oxygen Sensor**: Features self-diagnosis, avoids electrolyte changes affecting measurement accuracy, and allows for quick response in dissolved oxygen measurement [12]. - **AP-100 Biological Process Biochemical Analyzer**: Automatically calculates feeding rates and controls feeding volume or mass, enabling "unmanned" biological culture processes [14]. - **AMF-101 Integrated Online Bioreactor**: Incorporates sterile automatic sampling and online biochemical detection, utilizing new optical technology for dynamic adjustments in feeding strategies [16]. Industry Event - Sieman Technology will participate in the SynBioCon 2025, scheduled for August 20-22, 2025, in Ningbo, Zhejiang, focusing on synthetic biology and green manufacturing [17]. - The conference will explore five key areas: AI + biological manufacturing, green chemistry and new materials, future food, future agriculture, and beauty raw materials, aiming to discuss trends and innovations in the biomanufacturing industry [17].

Group 1 - The establishment of the Agricultural Biological Manufacturing - Feed Innovation Consortium aims to enhance collaboration among leading enterprises, universities, and research institutions to drive technological and industrial innovation in the feed industry [1] - The consortium will utilize synthetic biology technology to create microbial cell factories for producing high-quality, environmentally friendly, and nutritious biological feed products, promoting a resource-efficient and ecologically safe aquaculture production system [1] - The first working meeting of the consortium was attended by ten founding units, including Beijing Dabeinong Technology Group Co., Ltd., and various universities and research institutes, to discuss key tasks and division of responsibilities [1] Group 2 - The SynBioCon 2025 conference will be held from August 20-22 in Ningbo, Zhejiang, focusing on five key areas: AI + biological manufacturing, green chemicals and new materials, future food, future agriculture, and beauty raw materials [3] - The conference aims to explore the development trends of the biological manufacturing industry during the 14th Five-Year Plan and identify innovative technologies and products that will sustain the industry's vitality [3] - The event will facilitate the scaling of products and the transfer and transformation of scientific and technological achievements [3]

Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through initiatives like green manufacturing and intelligent manufacturing [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan, discussing innovative technologies and products that will sustain the industry's vitality [1]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and supported by various academic and industry institutions, including Peking University and the China Society of Biotechnology [2]. Group 3: Highlights of the Conference - Key highlights include forums and closed-door discussions on biomanufacturing trends, youth innovation technology sharing, and over 100 financing project roadshows to discover new cooperation opportunities [5]. - The event will gather leading enterprises, top universities, and investment institutions to foster collaboration across the biomanufacturing ecosystem [5]. Group 4: Agenda and Activities - The first day features a closed-door seminar focusing on the development trends and growth points of biomanufacturing, inviting industry leaders and experts for in-depth discussions [9]. - Subsequent days will include various specialized forums covering topics such as green chemicals, AI in biomanufacturing, future food and agriculture, and beauty raw materials [13][15][18]. Group 5: Specialized Topics - Specific discussions will address the development of bio-based chemicals, new carbon source biomanufacturing, and the application of AI in enzyme discovery and industrial fermentation processes [16][17]. - The conference will also explore the biomanufacturing of high-value food ingredients and the integration of biotechnology in cosmetic applications [20].

Core Viewpoint - The article highlights the upcoming SynBioCon 2025 event, focusing on the potential of synthetic biology and biomanufacturing, showcasing innovative research teams, technologies, and products in the field [2][5][14]. Group 1: Event Overview - The SynBioCon 2025 will take place from August 20-22 in Ningbo, Zhejiang, featuring a special session called the "Biomanufacturing Youth Forum" with nearly 30 presentations [2][10]. - The event aims to facilitate the exchange of innovative research outcomes and promote collaboration between researchers and industry stakeholders [2][14]. Group 2: Forum Details - The Youth Forum will include presentations from various universities and research institutions, such as Anhui University of Technology and South China University of Technology [4][5]. - The forum is designed to help attendees understand key scientific issues, solutions, and future development directions in biomanufacturing within a 15-minute format [3][14]. Group 3: Special Activities - A closed-door high-level seminar will discuss the trends and growth points of biomanufacturing as part of the event's agenda [11]. - The event will also feature project roadshows and technology showcases, inviting participation from leading parks and investment institutions [14][20]. Group 4: Thematic Discussions - The conference will cover various topics, including green chemicals, new materials, AI in biomanufacturing, and future food and agriculture [15][17][19]. - Specific focus areas include the development of bio-based materials, non-grain carbon source utilization, and the application of AI in enhancing biomanufacturing processes [18][22].

Group 1 - The core project is the flexible production line renovation project for synthetic biology at Zhejiang Haizheng Pharmaceutical Co., Ltd., with a total investment of 171.06 million yuan, including 5.1 million yuan for environmental protection [2][4]. - The project aims to produce 72,000 tons of 60% liquid glucose, 93,816 tons of 30% liquid glucose, 1,500 tons of yeast, and various other products annually, including 2,000 tons of HS31101 sulfate and 1,000 tons of HS31101 hydrochloride [2][3]. - The project will utilize existing production lines in the Y108, Y109, Y110, Y112, and Y27 workshops at the Yantou plant [2][3]. Group 2 - The fourth Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held in Ningbo, Zhejiang, from August 20 to 22, focusing on five key areas: AI + biological manufacturing, green chemicals and new materials, future food, future agriculture, and beauty raw materials [5][6]. - The conference aims to explore the development trends of the bio-manufacturing industry during the 14th Five-Year Plan and discuss innovative technologies and products that will sustain the industry [5].

Core Viewpoint - The article discusses the advancements in third-generation biorefining technology that utilizes one-carbon (C1) resources, such as CO2, to produce biofuels and chemicals, contributing to carbon capture and utilization, and supporting carbon neutrality goals [1][3][9]. Summary by Sections 1. Development of Biorefining Technology - The oil crisis in the 1970s spurred research and industrialization of biofuels, leading to the introduction of biorefining concepts in the 1980s [7]. - The first-generation biorefining technology, using food crops, faced challenges related to resource efficiency and competition with food production [8]. - The second-generation technology, based on lignocellulosic biomass, has potential but is hindered by high costs and technical barriers [8]. 2. Third-Generation Biorefining Technology - Third-generation biorefining aims to convert CO2 and renewable energy sources into fuels and chemicals, overcoming limitations of previous technologies [9]. - This technology has shown significant progress, with over 10 carbon fixation pathways validated, and some CO2 fixation technologies have reached commercialization [4][9]. - Examples include projects that convert industrial emissions into bioethanol, significantly reducing CO2 emissions [4]. 3. Carbon Fixation Pathways - More than 10 carbon fixation pathways have been identified, including natural pathways like the Calvin cycle and engineered pathways [11][36]. - The article details various pathways, such as the Wood-Ljungdahl pathway and reductive TCA cycle, highlighting their unique characteristics and potential for industrial application [16][33]. 4. Engineering of Carbon Fixation - Key factors influencing carbon fixation efficiency include energy sources, substrate types, and enzyme characteristics [36]. - Engineering efforts focus on optimizing microbial strains for better CO2 utilization and product yield, with examples of successful modifications in various microorganisms [38]. 5. Commercialization and Future Prospects - The commercialization of third-generation biorefining technologies is underway, with successful projects demonstrating the feasibility of using CO2 as a raw material [4][9]. - Future developments are expected to enhance the efficiency and cost-effectiveness of these technologies, contributing to sustainable bio-manufacturing [9][36].

Core Viewpoint - The article discusses the "Action Plan for Promoting High-Quality Development of the Biological Manufacturing Industry in Hainan Province (2025-2027)", which aims to enhance the biological manufacturing sector in Hainan through a structured development path focusing on marine biological manufacturing and breeding [1][2]. Group 1: Development Strategy - The "5+8+N" development path emphasizes two main areas: marine biological manufacturing and biological breeding, targeting five key sectors: biomedicine, biological food, biological agriculture, biological materials, and biological chemicals and energy [2][3]. - The plan includes establishing an innovation center for marine biological manufacturing by the end of this year and aims to cultivate several flagship products and key industrial chain projects [2][3]. Group 2: Advantages of Hainan - Hainan possesses unique advantages for developing the marine biological manufacturing industry, including rich marine resources, favorable policies from the free trade port, established platforms for deep-sea biological development, and a solid industrial foundation with a nearly 800 billion yuan output in high-end food processing and biomedicine [3][4]. - The province plans to develop marine bio-based materials using resources like blue and red algae to produce materials such as polylactic acid and carrageenan fibers [3]. Group 3: Future Goals - By the end of 2027, Hainan aims to create a "dual-core, dual-wing, multi-point" industrial spatial layout centered around Haikou and Sanya, with the goal of achieving over 100 billion yuan in biological manufacturing output and enhancing the overall quality of the industry [4][5].

Core Viewpoint - Dapu Biotech aims to create a new generation of intelligent life science solutions, focusing on the deep integration of AI and biotechnology [1] Company Overview - Dapu Biotech was founded in 2018, incubated at the Hong Kong University of Science and Technology, and is a leading enterprise in high-throughput droplet microfluidics technology in China [5] - The company has R&D and production centers in Shenzhen and Jiaxing, with a team of nearly 100 people dedicated to applying droplet microfluidics technology in biomedicine and precision medicine [5] - Dapu Biotech aims to provide a complete solution integrating the R&D and production of microfluidic chips, instruments, and reagents [5] Product Offerings - The company has commercialized multiple scientific instruments based on droplet microfluidics technology, including: - CytoSpark® Droplet Microfluidic High-throughput Screening System - OMNIdrop® System - Galaxy Single Cell Analysis System - Nebula dPCR System - Exostar Extracellular Vesicles Analysis System - These products are applicable in various fields such as antibody screening, enzyme directed evolution, strain screening, small molecule compound screening, cancer research, tumor early screening, virus quantification, and biopharmaceutical quality control [6] System Advantages - OMNIdrop® System features: - Multifunctional integration of droplet generation, fusion, reading, and sorting - Dual-drive pressure system for easy switching - High-speed droplet generation of 100 to 8000 droplets per second, with a million droplets prepared in just 10 minutes - High compatibility with commonly used biological experimental consumables [9] - CytoSpark® CSP System advantages include: - Efficient screening of complex transmembrane proteins - Unique non-activation screening technology - Breakthrough in single-experiment coverage of over one million B cells, improving efficiency by 10 to 100 times [14] Industry Events - The SynBioCon 2025 conference will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biological manufacturing, and exploring trends in the biomanufacturing industry [18]

Core Viewpoint - The article highlights the upcoming "Synthetic Biology and Green Bio-Manufacturing Conference 2025" (SynBioCon 2025) taking place in Ningbo, Zhejiang from August 20-22, focusing on innovative achievements in synthetic biology and bio-manufacturing [2][14]. Group 1: Event Details - The "Youth Forum on Bio-Manufacturing" will be held as a special session during SynBioCon 2025, aimed at showcasing innovative research teams, technologies, and products in the field [2]. - The forum will provide a platform for discussing scientific issues, solutions, achievements, scalability, and future directions in the research area [3]. - Registration is open for universities and research institutions to share their findings and innovations [4]. Group 2: Participation and Registration - Participants can choose to register for either the Youth Forum or the Technology Achievement Exhibition [5]. - The forum will take place on August 20, with limited seating available (only 30 seats) [6]. - The Technology Achievement Exhibition will feature 100 innovative projects in synthetic biology and bio-manufacturing, allowing for on-site display and networking opportunities [6]. Group 3: Organizing Institutions - The event is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and supported by various institutions including the Chinese Society of Biotechnology and local industry alliances [12][14].