Core Viewpoint - The article discusses the significant advancements in the field of functional oils, particularly focusing on the clinical research conducted by Peking University and Zhidai Technology, which highlights the health benefits of glycerol diester oil in improving lipid metabolism and reducing cardiovascular disease risks [2][5][14]. Group 1: Research Background - Cardiovascular disease prevention requires lifestyle interventions, with dietary fat intake being a critical factor. Over 95% of traditional cooking oils are triglycerides, which are linked to increased triglyceride levels and related health risks [4]. - The prevalence of cardiovascular diseases in China has surpassed 330 million, necessitating effective management strategies to address public health and healthcare costs [4]. Group 2: Clinical Research Findings - A randomized controlled trial involving 120 healthy participants was conducted over 8 weeks to assess the effects of glycerol diester oil on various metabolic indicators [7][10]. - The study showed significant improvements in six key lipid metabolism indicators, including blood lipids, visceral fat, uric acid, body fat, and waist circumference, without altering participants' usual dietary habits [11][12]. Group 3: Implications and Innovations - Zhidai Technology, as a pioneer in the glycerol diester field, fills a research gap in the clinical application of high-purity glycerol diester oils, providing reliable data to support functional oils' use [14]. - The research offers an innovative non-pharmaceutical intervention for high-risk populations, allowing for lipid metabolism rebalancing through oil substitution without dietary changes, thus contributing to chronic disease prevention strategies [14].

Core Viewpoint - Xierman Technology aims to provide cost-effective, high-precision, and rapid testing analytical instruments and methods for China's biopharmaceutical and food enterprises, thereby reducing daily operational costs [2]. Group 1: Company Overview - Xierman Technology focuses on the research and production of online dissolved oxygen electrodes, pH electrodes, cell culture biochemical analyzers, biosensors, and ion concentration analyzers [2]. - The company officially opened on September 27, 2025, in Wuxi, with industry guests, partners, and company leaders attending the ceremony [2][3][4]. Group 2: Industry Context - The biopharmaceutical industry is experiencing unprecedented development opportunities, making the establishment of Xierman in Wuxi timely and promising [6]. - The company addresses the challenge of foreign monopolization of core technologies in high-end biological equipment [8]. Group 3: Product and Technology - All products have independent intellectual property rights, with mass production achieved in four major product categories, demonstrating technology levels comparable to or exceeding advanced domestic and international products [8]. - The newly launched AMF-101 integrated online detection bioreactor utilizes sterile microfluidic technology for automatic biochemical detection of culture solutions and features an intelligent closed-loop control system, showcasing the company's technological innovation [12][13]. Group 4: Service Commitment - Xierman is committed to creating a "concierge" service system, covering laboratory design, equipment installation, personnel training, and post-maintenance, truly implementing a customer-centric philosophy [13]. Group 5: Future Aspirations - The opening of Xierman marks the beginning of a new journey, with the company steadily moving towards the goal of becoming a world-class manufacturer of biological culture solutions [15].

Core Viewpoint - The article highlights the rapid development and investment in the synthetic biology manufacturing industry in Changde, showcasing significant projects and collaborations that aim to enhance the sector's growth and innovation [2][5]. Group 1: Industry Development - The 2025 China Synthetic Biology Manufacturing Technology Innovation Forum was held in Changde, where 24 projects related to technology innovation and strategic cooperation were signed [2]. - Changde's synthetic biology manufacturing enterprises achieved a total output value of 8.759 billion yuan from January to August, marking a year-on-year increase of 24.01% [5]. - The local government has implemented regulations to promote the synthetic biology manufacturing industry, making it the first local legislation of its kind in China [5]. Group 2: Company Initiatives - ZhiNuo Technology focuses on developing high-value natural products using synthetic biology and fermentation engineering, with projects covering various sectors including dyeing, daily chemicals, and human health [4]. - The company has successfully completed a Pre-A round financing of several million yuan, which will support its production capacity, pipeline expansion, and commercialization efforts [4]. - ZhiNuo's project for producing a thousand-ton level of bio-based pigments and functional raw materials is set to begin trial production in the second half of next year [2]. Group 3: Strategic Collaborations - Several universities and enterprises signed major technology transfer and joint research agreements at the forum, indicating a strong trend of collaboration between academia and industry [2]. - Changde is establishing multiple synthetic biology manufacturing bases, focusing on different sectors such as biomedicine, food additives, and bio-based materials [5][6].

Core Viewpoint - The article emphasizes the development of non-grain biomass resources for energy and bio-based materials, highlighting the upcoming NFUCon 2025 forum aimed at discussing commercialization paths, technological challenges, and opportunities in the biomass industry [2]. Group 1: Forum Overview - The NFUCon 2025 will be held from November 27-29, 2025, in Hangzhou, Zhejiang, organized by DT New Materials and the National Key Laboratory of Bio-based Transportation Fuels [2][3]. - The forum will gather industry representatives and experts to explore key areas such as biomass green pretreatment, non-grain sugars, bio-based chemicals and materials, and biomass energy [2][4]. Group 2: Forum Agenda - The forum will feature a series of specialized sessions, including: - Session 1: Biomass Green Pretreatment focusing on steam explosion technology and efficient pretreatment methods [6]. - Session 2: Non-grain sugars and their industrial applications [7]. - Session 3: Bio-based chemicals and their production processes [8]. - Session 4: Non-grain bio-based materials and their commercialization [8]. Group 3: Special Activities - A special activity titled "Technology Achievement Display and Matching" will be held to promote innovation and commercialization in the biomass sector, showcasing 50 innovative projects with commercial potential [9]. Group 4: Industry Participation - The forum will attract various participants, including: - Production companies involved in biomass energy and chemicals, cellulose materials, and green composite materials [14]. - Academic institutions focusing on biomass chemistry, advanced catalysis, and resource utilization [14]. - Equipment and solution providers for biomass processing and analysis [14].

Core Viewpoint - The article discusses the innovative approach taken by the Tianjin Institute of Industrial Biotechnology to address the scarcity of sandalwood resources through synthetic biology techniques, specifically the development of a yeast cell factory for efficient production of sandalwood alcohol [1][2]. Group 1: Sandalwood Alcohol Production - Sandalwood alcohol, derived from sandalwood heartwood, is highly valued in various industries, but its natural resource is scarce and expensive, priced at approximately $2500 per kilogram [1]. - The research team successfully enhanced the total yield of sandalwood alcohol and sandalwood olefin by 5.1 times, achieving a concentration of 0.9 g/L in initial experiments [2]. - The conversion rate from sandalwood olefin to sandalwood alcohol was initially 31.0%, which improved to 60.6% through innovative engineering of the P450 enzyme [2]. Group 2: Technological Innovations - The team utilized a targeted signal peptide to localize key enzymes within peroxisomes, overcoming initial challenges related to enzyme integration [2]. - By truncating the transmembrane domain of the P450 enzyme and fusing it with a membrane anchoring unit, the team achieved precise localization on the peroxisome membrane, significantly improving conversion rates [2]. - The final production in a 5-liter fermentation tank reached a record yield of 10.4 g/L, marking a significant advancement in the sustainable production of sandalwood oil [2]. Group 3: Research Support and Future Directions - The research received funding from several national projects, including the National Key R&D Program and the National Natural Science Foundation [3]. - The results have been published in the Journal of Agricultural and Food Chemistry and multiple patents have been applied for [3]. - The Tianjin Port Free Trade Zone is actively supporting the development of the bio-manufacturing industry, aiming to transform innovative research outcomes into practical applications [3].

Core Viewpoint - The article discusses the economic feasibility of bio-based polymers, the challenges they face, and the industrialization opportunities in this field, highlighting recent advancements and research directions from the Ningbo Institute of Materials Technology and Engineering [2][5][6]. Summary by Sections Economic Feasibility of Bio-based Polymers - Bio-based materials can theoretically replace petroleum, coal, and natural gas resources using biomass generated through photosynthesis, with various chemical and microbial methods available for conversion [3][5]. - The price development of polylactic acid (PLA) indicates significant potential for converting biomass into bio-based materials [5]. Research Directions and Achievements - The Zhejiang Key Laboratory focuses on three main research areas: efficient conversion of non-food biomass, design and synthesis of high-quality bio-based polymers, and high-quality processing applications of bio-based materials [5][8]. - The laboratory has made progress in four key areas: cellulose conversion to sugars, furan dicarboxylic acid (FDCA) and its polyesters, biodegradable polymers, and bio-based additives [8][9]. Cellulose Conversion - The conversion of cellulose to glucose is challenging but essential for developing non-food bio-based materials. The team has achieved a glucose yield of over 85% and a cellulose conversion rate of 100% using a novel enzyme-like catalyst [9][13][10]. Furan Dicarboxylic Acid (FDCA) and Its Polyesters - FDCA is a promising bio-based platform compound with advantages over traditional petroleum-based counterparts, such as better rigidity and sustainability [15][17]. - The team has pioneered a non-food route for FDCA production, which is more sustainable and efficient, and has initiated pilot-scale production [20][21]. Biodegradable Polymers - The team is addressing the slow degradation rates of existing biodegradable polymers by developing a new oxalic acid-based polyester that can degrade in marine environments [24][27]. Bio-based Additives - There is a significant market for bio-based compatibilizers, with the global market projected to reach 64.82 billion yuan in 2024. The team has developed a bio-based compatibilizer with a grafting rate of up to 1.5%, outperforming traditional options [28][31][29]. Conclusion - The bio-based polymer sector has seen rapid development over the past 20 years, with some materials already commercialized. The industry is expected to continue growing, providing effective alternatives to fossil-based polymers [31].

Core Viewpoint - The article highlights the advancements in synthetic biology and biomanufacturing, particularly focusing on the recognition of key projects and experts in the field by the Ministry of Science and Technology of the People's Republic of China for the 2025 National Science and Technology Awards [2][5]. Group 1: National Science and Technology Awards - A total of 60 projects for the National Natural Science Award, 51 for the National Technology Invention Award, and 134 for the National Science and Technology Progress Award passed the preliminary evaluation [2]. - Notable projects include research on catalysts, reactors, and processes for carbon dioxide conversion, and advanced manufacturing technologies for green chiral pesticides [2][5]. - Key contributors to these projects include professors and researchers from prestigious institutions such as the University of Science and Technology of China and Zhejiang University [2][5]. Group 2: Key Projects and Contributors - The project on catalysts and processes for carbon dioxide conversion is led by notable figures such as Professor Zeng Jie and Academician Yang Jinlong, with a preliminary evaluation suggestion of a second prize [3]. - The project on advanced manufacturing technologies for green chiral pesticides involves contributors like Academician Zheng Yuguo and Professor Xue Yaping, also suggested for a second prize [5]. - The involvement of multiple companies and institutions indicates a collaborative effort in advancing biomanufacturing technologies [2][5].

Core Viewpoint - The article highlights the recent signing of four major projects in Nanning High-tech Zone, with a total investment of 4.21 billion yuan, focusing on smart manufacturing, biomedicine, and circular economy, which injects new momentum into the cooperation between China and ASEAN [2][3]. Group 1: Project Overview - Four major projects signed include: 1. Guangxi Sihua Pharmaceutical Intelligent Manufacturing Base with an investment of 1.28 billion yuan, expected to achieve an annual output value of 6.5 billion yuan [2]. 2. Weilong Delicious Production Base with an investment of 1 billion yuan, focusing on high-end leisure food [2]. 3. Synthetic Biology Base led by Nanning Hanhe Bio, with an investment of 430 million yuan, aiming for an annual production of 3,400 tons of high-value products [2]. 4. Circular Economy Project by Northeast Asia Railway Group with an investment of 1.5 billion yuan, targeting the production of 200,000 tons of soda ash and 260,000 tons of ammonium sulfate [2]. Group 2: Support and Infrastructure - Nanning High-tech Zone has provided comprehensive support for project construction, allocating 87.93 million yuan to ensure key elements such as land, energy, and funding are in place [3]. - A dedicated service mechanism for major industrial projects will be implemented to facilitate the entire process from signing to operation, ensuring timely project execution [3]. Group 3: Synthetic Biology Development - The signing of two synthetic biology bases marks a significant step in the development of the synthetic biology industry in Nanning High-tech Zone, aiming to attract more enterprises and talent to create an industrial cluster effect [5]. - Hanhe Bio plans to establish a full-chain system from basic research to industrialization, focusing on various product matrices in plant nutrition, animal nutrition, human health, and environmental microbiology [5].

Core Viewpoint - The article discusses South Korea's initiative to promote Sustainable Aviation Fuel (SAF) through a mandatory blending system, aiming for carbon neutrality in aviation and the development of new industries [3][4]. Group 1: SAF Blending Mandate - South Korea's roadmap includes a mandatory SAF blending ratio starting at 1% in 2027, increasing to 3-5% by 2030, and 7-10% by 2035, with specific evaluations set for 2026 and 2029 [4]. - The government will support the development of bio-based SAF through tax incentives, with facility investment support up to 25% and R&D support up to 40% [4]. Group 2: Global SAF Goals - Various countries have set their own SAF targets, including Japan aiming for a 10% replacement rate by 2030, Singapore targeting 3-5% blending by 2030, the UK planning to increase from 2% in 2025 to 22% by 2040, and the EU requiring a 2% blending ratio this year, with a goal of 70% by 2050 [5]. Group 3: SAF Production Pathways - The article highlights the potential of non-grain alcohol-based SAF production pathways, particularly the Alcohol-to-Jet (AtJ) process, which is currently in the commercial pilot stage [6]. - Research focuses on efficiently constructing long carbon chain products from non-grain biomass, with significant advancements made by a team at Zhejiang University in developing a one-step ethanol to C3+ olefins technology, which reduces operational complexity and costs while achieving high yields [7].

Core Viewpoint - The article emphasizes the development of non-grain biomass resources for energy and bio-based materials, highlighting the upcoming NFUCon 2025 forum aimed at discussing commercialization paths and technological advancements in this sector [2]. Group 1: Forum Overview - The NFUCon 2025 will be held from November 27-29, 2025, in Hangzhou, Zhejiang, organized by DT New Materials and the National Key Laboratory of Bio-based Transportation Fuels [2][3]. - The forum will gather industry representatives and experts to explore key areas such as green pretreatment of biomass, non-grain sugars, bio-based chemicals and materials, and biomass energy [2][4]. Group 2: Forum Agenda - The forum will feature a series of specialized sessions, including: - Session 1: Green pretreatment technologies [6]. - Session 2: Non-grain sugars development and industrial practices [10]. - Session 3: Bio-based chemicals and their industrial applications [10]. - Session 4: Non-grain bio-based materials [10]. - Session 5: Biomass energy, focusing on methanol, fuel ethanol, biogas, and sustainable aviation fuel (SAF) [9][10]. Group 3: Supporting Organizations - The forum is supported by various academic and research institutions, including Zhejiang University and its associated laboratories, which focus on bio-based materials and engineering [3][4]. - The event will also feature collaborations with media and organizations related to biodegradable materials and bioenergy [4]. Group 4: Innovation and Commercialization - The forum will include a special activity for showcasing and connecting 50 innovative projects in the biomass utilization field that have commercial potential [9]. - This initiative aims to promote the transformation of scientific achievements into practical applications within the industry [9].