Core Viewpoint - The article discusses the controversy surrounding Huaxi Biological's rebuttal of the claims made by nine brokerage firms regarding hyaluronic acid being "outdated" and the promotion of recombinant collagen as a superior alternative, highlighting the impact of these claims on the market and the industry [2][4][9]. Group 1: Company Actions - Huaxi Biological publicly refuted the claims about hyaluronic acid and named nine brokerage firms for misleading reports, which has led to some brokerages retracting their reports and issuing apologies [2][8]. - The company received support from two industry associations before making its statement and has reported the matter to the China Securities Regulatory Commission [2][8]. - As of May 23, three of the ten reports mentioned have been removed from public access, while the remaining seven are still available for viewing [8][9]. Group 2: Industry Context - The medical beauty industry is characterized by a high overlap between capital market participants and enterprise users, making capital evaluations significantly impactful on the competitive landscape, which explains Huaxi Biological's strong response [2][4]. - The article emphasizes that the claims made in the brokerage reports lack scientific basis and are driven by speculative capital, which could harm a key industry in China [6][9][24]. Group 3: Scientific Claims - Huaxi Biological argues that the reports promoting recombinant collagen over hyaluronic acid are misleading and lack substantial scientific evidence, asserting that both substances have their unique benefits and should not be directly compared [23][24]. - The company highlights that the regulatory approvals for hyaluronic acid products far exceed those for recombinant collagen, indicating a stronger safety profile for hyaluronic acid [25][26]. Group 4: Regulatory Environment - The article notes that the regulatory environment for brokerage reports is tightening, with recent inspections revealing issues in compliance and the need for better management of report quality and information sources [18][20]. - There is a growing concern about the potential for misleading information in brokerage reports, which could lead to regulatory actions against the firms involved if found to be in violation of established guidelines [21][22].

Investment Rating - The industry investment rating is "Positive" (maintained) [1] Core Viewpoints - The report highlights a steady recovery in social consumption, with April 2025 retail sales showing a year-on-year increase of 5.1%, and a total retail sales amount of 1618.45 billion yuan for the first four months of 2025, reflecting a 4.7% year-on-year growth [4][25] - The report suggests that the overall social consumption is expected to maintain stable growth due to effective policy measures aimed at boosting domestic demand, with a focus on the high-growth segments of gold jewelry and cosmetics [4][31] Summary by Sections Retail Market Overview - The retail industry index closed at 2110.59 points, down 1.61% for the week, underperforming the Shanghai Composite Index, which fell by 0.57% [6][15] - The jewelry sector showed the highest growth among retail segments, with a weekly increase of 7.56% and a year-to-date increase of 18.83% [17][20] Social Consumption Trends - In April 2025, the retail sales of consumer goods increased by 5.1%, driven by favorable consumption policies and the Qingming holiday effect [28][31] - Online retail sales for the first four months of 2025 reached 4741.9 billion yuan, growing by 7.7%, with physical goods online retail accounting for 24.3% of total retail sales [28][29] Investment Recommendations - Investment focus on high-growth segments under emotional consumption themes, particularly in gold jewelry and cosmetics [7][39] - Recommended companies in the gold jewelry sector include Laopuhuangjin, Chaohongji, and Zhou Dasheng, which are expected to benefit from differentiated product offerings and consumer insights [39][41] - In the cosmetics sector, recommended brands include Proya, Shangmei, and Juzi Biological, which are positioned to capitalize on the ongoing trend of domestic brand growth [39][41] Company Performance Highlights - Proya reported a 28.9% year-on-year increase in net profit for Q1 2025, driven by new product launches [40] - Chaohongji achieved a 25.4% year-on-year revenue growth in Q1 2025, indicating strong brand momentum [40] - Zhou Dasheng's revenue for Q1 2025 was down 47.3% year-on-year, highlighting challenges in the current market environment [40]

Investment Rating - The report indicates a strong growth potential for the hyaluronic acid underwear industry, with a projected market size increase from 1 billion to 10.4 billion yuan from 2022 to 2024, reflecting a compound annual growth rate (CAGR) of over 300% [29][32]. Core Insights - The rapid development of the hyaluronic acid underwear market is driven by technological advancements and innovation, particularly in integrating hyaluronic acid into textiles for enhanced moisturizing properties [2][4]. - Consumer awareness and demand for functional and aesthetically pleasing clothing are significant growth drivers, with a notable shift towards products that offer both warmth and skin benefits [3][40]. - The market faces challenges such as product homogenization, leading to intensified brand competition and a focus on product differentiation and technological innovation as core strategies for future growth [3][34]. Summary by Sections Industry Overview - Hyaluronic acid is recognized for its natural safety and biodegradability, making it a key ingredient in the development of moisturizing functional textiles [15][22]. - The market for hyaluronic acid underwear is characterized by a transition from basic thermal properties to dual benefits of warmth and skin care [4][22]. Market Size - The market size for hyaluronic acid underwear is expected to grow from 14.5 billion yuan in 2025 to 25.3 billion yuan by 2029, maintaining a stable upward trend despite a slowdown in growth rate [29][32]. Driving Factors - The growth of the hyaluronic acid underwear industry is supported by favorable policies that promote innovation and market expansion, aligning with trends towards health and sustainability [26][27]. Competitive Landscape - The online retail market for hyaluronic acid underwear shows significant concentration, with leading brands like Qiaolaiti dominating in market share and consumer recognition [35][34]. - The competitive environment is marked by a reliance on digital platforms for sales, particularly Douyin, which accounts for over 80% of sales in this segment [35][34]. Consumer Demand - There is a growing consumer preference for functional, stylish, and versatile clothing, with significant interest in the moisturizing benefits of hyaluronic acid products [40][42]. - The search index for keywords related to hyaluronic acid underwear on platforms like Douyin has shown substantial growth, indicating strong market potential and consumer interest [42][32].

Core Viewpoint - The company is advancing its product offerings in the field of ergothioneine, with significant developments in both raw materials and functional skincare products [1] Group 1: Product Development - The company’s food-grade ergothioneine is set to receive Self-GRAS certification in the U.S. by 2024 [1] - The company has launched Bioyouth™-EGT Pro and Bioyouth™-EGT Pure, with full production capacity at a tonnage level, and raw material sales have exceeded one million [1] Group 2: Industry Standards - The company has led the drafting of the group standard for high-purity ergothioneine in cosmetics, which was officially implemented in September 2023 [1] Group 3: Nutritional Science Innovation - The company focuses on four core areas and has developed a product matrix around key raw materials such as hyaluronic acid, ergothioneine, rhodiola rosea glycosides, and GABA [1] - Oral ergothioneine products are now available on Tmall through the company’s flagship store, utilizing cross-border e-commerce for sales [1]

Core Viewpoint - The recent controversy involving Huaxi Biological and brokerage reports highlights the need for improved interaction and accountability between listed companies and brokerage research teams, suggesting a potential shift in the dynamics of this relationship [6][8]. Group 1: Company Actions and Statements - Huaxi Biological issued a follow-up statement on May 21, further explaining its concerns regarding brokerage reports published on May 17, specifically addressing misleading conclusions about the medical aesthetics industry [4][5]. - The company pointed out that certain brokerage reports claimed that collagen products outperform hyaluronic acid without any supporting public data or scientific research [4][6]. - Huaxi Biological emphasized that its intention in naming the brokerages was not to attack them but to encourage a more informed and collaborative approach to industry analysis [5][6]. Group 2: Industry Implications - The incident has prompted discussions about redefining the interaction between listed companies and brokerage research, potentially leading to a more rigorous review process for research reports [8][9]. - Analysts suggest that this situation serves as a warning for brokerages to enhance the professionalism and accuracy of their reports, as previous instances of regulatory scrutiny have already highlighted issues within the industry [9][10]. - The ongoing scrutiny of brokerage reports may lead to a more cautious approach in the future, with an emphasis on compliance and thorough validation of research findings [10][11].

Core Viewpoint - The recent discussions surrounding hyaluronic acid and recombinant collagen in the medical beauty industry have intensified, particularly following Huaxi Biological's publications defending hyaluronic acid's relevance and efficacy over recombinant collagen [1][4][5]. Group 1: Company Response and Market Dynamics - Huaxi Biological has issued statements refuting claims that hyaluronic acid is outdated, emphasizing the importance of both hyaluronic acid and collagen in skin health, and their interdependent roles in extracellular matrix (ECM) function [4][5]. - The company highlighted that it holds the highest number of approved Class III medical device certifications for hyaluronic acid products, asserting that there is no evidence to suggest that recombinant collagen is safer than hyaluronic acid [5]. - The shift in market focus from hyaluronic acid to recombinant collagen has led to a decline in the stock prices and performance of traditional hyaluronic acid companies, while recombinant collagen firms have seen significant gains [6]. Group 2: Financial Performance - Huaxi Biological reported a revenue decline of 11.61% year-on-year, with total revenue of approximately 5.371 billion yuan and a net profit drop of 70.59%, amounting to about 174 million yuan for 2024 [6][7]. - The company’s medical beauty segment showed positive growth, with raw material business revenue increasing by 9.47% to 1.236 billion yuan, while the medical terminal business grew by 32.03% to 1.44 billion yuan [7]. - The significant decline in overall performance was attributed to challenges in the consumer goods segment, which faced intensified competition and strategic adjustments, resulting in a 31.62% revenue drop to 2.569 billion yuan [7]. Group 3: Management Changes and Corporate Governance - In response to internal issues, Huaxi Biological has initiated a major management reform, focusing on addressing corruption and improving corporate governance, with a strict deadline for employees to report any misconduct [9][10]. - The company has undergone significant personnel changes, including the retirement of senior executives and the appointment of new management to align with strategic development needs [10]. - The management reform aims to correct previous lax practices and establish a more robust operational framework for long-term growth [9].

Core Viewpoint - Huaxi Biological criticized ten research reports from nine brokerages, claiming they misled the market by promoting a "hyaluronic acid obsolescence theory" in favor of recombinant collagen products [2][3][5] Group 1: Research Reports Criticism - Huaxi Biological specifically named four reports from brokerages including Huatai Securities and Anxin Securities, which emphasized the advantages of recombinant collagen over hyaluronic acid in terms of efficacy and safety [3][5] - The reports in question did not explicitly use the term "obsolete" but suggested that collagen had superior applications in certain scenarios [5] - Huaxi Biological's article indicated that the emergence of the "hyaluronic acid obsolescence" narrative was driven by "restless capital" seeking new investment themes [3][9] Group 2: Timeline and Context - The criticism of the research reports is rooted in a timeline starting from 2022, when the recombinant collagen concept gained traction in the capital market [7][10] - Huaxi Biological itself entered the recombinant collagen market in April 2022 by acquiring a 51% stake in Beijing Yierkang Biological Engineering for 233 million yuan [9] - The reports were published between 2022 and 2024, with the earliest being from August 2022 and the latest from February 2024 [8] Group 3: Regulatory and Compliance Issues - The article raised questions about the compliance and independence of the research reports, referencing the "Interim Regulations on the Release of Securities Research Reports" which mandates objectivity and fairness [10][11] - There were indications that some brokerages had deleted the criticized reports from the WIND platform, although they remained accessible on other platforms like Choice [5][11] - The production process of research reports involves ensuring data legality and undergoing compliance checks before publication, highlighting the importance of rigorous standards in the industry [11]

沪指5月22日下跌0.22%，申万所属行业中，今日上涨的有3个，涨幅居前的行业为银行、传媒、家用电 器，涨幅分别为1.00%、0.12%、0.04%。跌幅居前的行业为美容护理、社会服务，跌幅分别为2.03%、 1.80%。美容护理行业位居今日跌幅榜首位。 | 代码 | 简称 | 今日涨跌幅（%） | 今日换手率（%） | 主力资金流量（万元） | | --- | --- | --- | --- | --- | | 002094 | 青岛金王 | 6.60 | 38.89 | 49250.10 | | 600249 | 两面针 | 4.83 | 22.21 | 16705.65 | | 001328 | 登康口腔 | 2.73 | 14.01 | 2803.29 | | 688363 | 华熙生物 | -1.01 | 1.08 | 1449.76 | | 002511 | 中顺洁柔 | -0.14 | 1.34 | 1289.38 | | 300886 | 华业香料 | -5.41 | 21.25 | 262.17 | | 300955 | 嘉亨家化 | 3.58 | 24.50 | 122.21 | | 30 ...

Core Viewpoint - The ongoing debate between hyaluronic acid and recombinant collagen in the capital market highlights the challenges faced by companies like Huaxi Biological, which is experiencing a decline in revenue and net profit after reaching a peak in 2022 [2][6]. Group 1: Company Response and Market Dynamics - Huaxi Biological criticized the recent reports from several securities firms that favor recombinant collagen over hyaluronic acid, claiming these reports misrepresent the safety and efficacy of hyaluronic acid [3][4]. - The company emphasized the importance of a healthy industry ecosystem, stating that without it, no company can achieve long-term success or maintain competitive advantages [5][6]. - Huaxi Biological is undergoing a comprehensive management transformation in 2024, including business process restructuring and digitalization, to address the challenges in the current operating environment [2][6]. Group 2: Financial Performance - In 2024, Huaxi Biological reported a revenue of 5.371 billion yuan, a year-on-year decrease of 11.61%, and a net profit of 174 million yuan, down 70.59% [6]. - The skin science innovation business, which accounts for nearly half of the company's revenue, saw a significant decline of 31.62% in revenue, totaling 2.569 billion yuan [6]. - In contrast, the medical terminal business achieved a revenue of 1.44 billion yuan in 2024, marking a growth of 32.03% [7]. Group 3: Industry Trends and Competition - The medical aesthetics industry is witnessing a shift from hyaluronic acid to recombinant collagen and other regenerative products, driven by evolving consumer preferences and technological advancements [5][9]. - The market for recombinant collagen is growing rapidly, with companies like Jinbo Biological and Giant Bio achieving substantial revenue increases in 2024, indicating a competitive landscape with low market concentration [8][9]. - Huaxi Biological is also investing in recombinant collagen research and development, aiming to leverage synthetic biology for technological upgrades and high-quality applications [7][8].

5月21日晚间，华熙生物官方公众号发布消息，再次就透明质酸、重组胶原蛋白等问题进行回应。 在谈到对透明质酸市场的现在和未来看法时，华熙生物表示，任何产业领域都有一个共同点：当某一领域展现出良好 的赚钱效应后就会吸引大量资本和企业涌入，随之引发价格和利润的下滑。这个现象在透明质酸领域发生过，在其他 任何领域都会发生。 但并非所有的企业都会在低端竞争，华熙生物的进阶道路并非特殊，是在中国很多企业中发生过的，这就是进入高端 透明质酸市场，做精做深，做出新的延伸和高度。在医用和试验用的高端透明质酸和生物制造领域，华熙生物依靠健 全的酶库和全球最大的中式转化平台，占据着高端市场技术与品牌的制高点，并依靠透明质酸打开了庞大的糖生物产 业和细胞生物学的认知窗口。 对于如何看待重组胶原蛋白，华熙生物方面指出，首先，就像不能比较肝脏与肾脏孰强孰弱一样，在很多场景下，也 无法比较透明质酸（HA）与胶原蛋白孰强孰弱。透明质酸和胶原蛋白都是人体重要的物质，透明质酸与胶原蛋白的 互动，构成了细胞外基质ECM功能的核心，这两个物质形成了信号共生、力学共生、病理共损的三重关系： 1、在力学层面，HA凭借其卓越的高保水性和粘弹性，在细胞外基 ...