Core Viewpoint - The conflict between Genie Pharma, the largest shareholder of Mengke Pharmaceutical, and the founding team led by Zhengyu Yuan has intensified, particularly regarding a proposed private placement and change of control involving Haijing Pharmaceutical [1][2][3] Group 1: Shareholder Dispute - Genie Pharma holds 71.57 million shares of Mengke Pharmaceutical, accounting for 10.92% of the total share capital, and has voted against multiple proposals related to the private placement [2] - Genie Pharma has proposed to remove three directors, including founder Zhengyu Yuan, and to elect three new directors, highlighting the growing rift between the major shareholder and the founding team [2][4] - The disagreement stems from Mengke Pharmaceutical's recent announcement of a private placement to Haijing Pharmaceutical, which Genie Pharma has publicly criticized [1][3] Group 2: Private Placement Details - Mengke Pharmaceutical plans to issue 164 million shares to Haijing Pharmaceutical, raising up to 1.033 billion yuan, which would give Haijing a 20% stake and make it the controlling shareholder [1][3] - Genie Pharma has raised concerns about the financial stability of Haijing Pharmaceutical, questioning its ability to fund the private placement given its reported total assets of approximately 700 million yuan and total liabilities of about 300 million yuan [6][7] Group 3: Financial Performance and Challenges - Mengke Pharmaceutical has been facing financial difficulties, with cumulative losses of approximately 1.221 billion yuan from 2022 to mid-2025, and has not yet achieved profitability [10] - The company’s only commercial product, the antibiotic Contizolam, has limited market potential due to competition from other established products [9][10] - Mengke Pharmaceutical's cash flow has been negative for several years, with only 237 million yuan remaining as of mid-2025, raising concerns about its ability to fund ongoing research and development [10]

对于此次合作，盟科药业副总经理、首席技术官王星海表示："我们很高兴与蓬勃生物达成此次战略合 作。蓬勃生物作为国际领先的生物药开发解决方案提供者，拥有高效的创新生物药发现、开发和产业化 能力，以及完善的国际质量体系。此次与蓬勃生物合作开发若干创新型ADC药物，将最大限度地发挥 STOPIN平台技术的适用性及竞争力，并在全球范围内开发更具竞争优势的新型ADC药物。" 据了解，此次合作方蓬勃生物（ProBio），致力于为生物科技公司及制药公司提供一站式CDMO服务， 帮助全球客户加速新药研发进程，服务涵盖临床试验到商业化生产。 对于此次合作，蓬勃生物CEO国璋表示："我们非常高兴与盟科药业展开此次战略合作。盟科药业在小 分子药物研发领域积累了深厚经验，其创新的STOPIN平台为新一代ADC的安全性和疗效提升提供了突 破性的解决方案。蓬勃生物在抗体发现、CMC工艺开发及GMP生产方面拥有丰富的经验和国际领先的 技术平台。通过强强联合，我们将把双方的技术优势和资源整合，携手推进多款创新型ADC产品的开 发与全球化布局，为患者带来更安全、更有效的治疗选择，推动全球肿瘤治疗领域的发展。" （文章来源：证券时报网） 近日，上 ...

Core Viewpoint - The first major shareholder, Genie Pharma, publicly opposes the planned 1 billion yuan private placement by Mengke Pharmaceutical, which could lead to significant changes in the company's ownership structure and governance [3][4][5]. Group 1: Shareholder Opposition - Genie Pharma announced its intention to vote against the acquisition of Mengke Pharmaceutical by Nanjing Haiqing Pharmaceutical at the upcoming shareholders' meeting [3]. - Genie Pharma has also proposed the removal of three directors, criticizing the management team's capabilities and the company's ongoing losses [7][10]. - The opposition from Genie Pharma has led to a significant drop in Mengke Pharmaceutical's stock price, which fell by 10.96% to 8.61 yuan per share following the announcement [5]. Group 2: Financial and Operational Concerns - Mengke Pharmaceutical has not launched any new products since its market entry three years ago and has not achieved profitability, with continuous losses reported [6][18]. - The company aims to leverage the investment from Haiqing Pharmaceutical to break its reliance on a single product and improve its financial situation [6][15]. - Financial data shows that Mengke Pharmaceutical's net losses from 2021 to 2024 totaled over 1.3 billion yuan, with a significant decline in net assets since its IPO [20][21]. Group 3: Haiqing Pharmaceutical's Role - Haiqing Pharmaceutical plans to invest 1.033 billion yuan in Mengke Pharmaceutical, acquiring a 20% stake, which would make it the controlling shareholder [4][8]. - Concerns have been raised regarding the uncertainty of Haiqing Pharmaceutical's funding for the private placement and its potential impact on Mengke Pharmaceutical's financial stability [16]. - Haiqing Pharmaceutical's financial health is questioned, with total assets of approximately 700 million yuan and total liabilities of about 300 million yuan as of mid-2025 [16]. Group 4: Management and Strategic Issues - The management team of Mengke Pharmaceutical has faced criticism for its inability to generate profits and for the company's deteriorating financial condition [17][19]. - The company has been heavily reliant on its sole product, Kangtaizuoan, which has seen increasing sales but is insufficient to cover overall operational costs [22][23]. - Mengke Pharmaceutical's high sales expenses, which reached 110 million yuan in 2024, have raised concerns about the sustainability of its business model [23][25].

中国经济网北京9月25日讯盟科药业(688373.SH)今日收报8.61元，跌幅10.96%。 光大证券股份有限公司研究员王明瑞、叶思奥9月23日发表研报《盟科药业-U(688373)：海鲸药业十亿 元定增控股助力研发销售生产全链条》称，维持公司"买入"评级。 ...

Group 1 - The stock prices of Mengke Pharmaceutical dropped over 10% [1] - Borui Pharmaceutical and Baicheng Pharmaceutical experienced declines of over 7% [1] - Other companies such as Yuekang Pharmaceutical, Kangchen Pharmaceutical, Yuandong Biological, and Fuxiang Pharmaceutical also saw significant drops in their stock prices [1]

Group 1 - Shengke Communication's shareholding by the National Integrated Circuit Industry Investment Fund has decreased from 19.6% to 15% after a total reduction of 18.8569 million shares [1] - Guoxin Technology plans to reduce its shares by up to 4.5% through various trading methods between September 30, 2025, and December 29, 2025 [1][2] - Jingzhida has delivered its first high-speed testing machine to a key domestic customer, aimed at semiconductor memory testing [4][5] Group 2 - Nanxin Pharmaceutical's shareholder plans to reduce shares by up to 3%, totaling 823.2 million shares, due to funding needs [6] - *ST Taihe's shareholder intends to reduce shares by up to 3% for operational management needs [7] - Xincheng Technology's shareholders and directors plan to reduce shares by up to 2.03% due to personal funding needs [8] Group 3 - Huati Technology is planning to acquire shares of Huayi Microelectronics, leading to a stock suspension due to uncertainties [9] - Ruima Precision's subsidiary has received a project notification with a total lifecycle sales estimate of approximately 5.56 billion yuan [10] - Guoguang Electric's shareholders plan to reduce shares by up to 3.85% through various trading methods [10] Group 4 - Cangge Mining's shareholder plans to reduce shares by up to 0.6% due to funding needs [11] - Jujiao Co., Ltd. intends to reduce shares by up to 3% due to personal funding arrangements [12] - Maqu'er plans to reduce shares by up to 2% due to funding needs [13] Group 5 - Caesar Travel's subsidiary intends to acquire 100% equity of Qingdao Hansa for 16 million yuan [14] - Xinde New Materials' shareholders plan to reduce shares by up to 3% through various trading methods [15] - Huadong Heavy Machinery's shareholders plan to reduce shares by up to 1.5% [16] Group 6 - Zhejiang Zhongcheng's shareholder plans to reduce shares by up to 3% due to personal funding needs [17] - Huaxi Securities' shareholder plans to reduce shares by up to 1% due to liquidity needs [18] - Ameng Pharmaceutical's major shareholder opposes the introduction of a strategic investor due to concerns over financial strength and compliance [19] Group 7 - *ST Rindong plans to invest 100 million yuan in Jiangyuan Technology, with a post-investment shareholding of 4.14% [20][21] - International Industry plans to issue shares to its controlling shareholder to raise no more than 662 million yuan for working capital [22][23]

Market Overview - On September 25, A-shares opened slightly lower, with the three major indices collectively in the red [1] - The Shanghai Composite Index decreased by 0.06%, the Shenzhen Component Index fell by 0.30%, and the ChiNext Index dropped by 0.45% [2] Sector Performance - The non-ferrous metals, media, electric equipment, and pharmaceutical sectors showed notable gains, with the nuclear fusion and copper industries being particularly active [2][4] - The nuclear fusion sector rose by 2.67%, while the copper industry increased by 2.63% [4] Copper Industry Insights - The copper industry index led the gains, with companies like Jingyi Co., Northern Copper, and Luoyang Molybdenum hitting the daily limit [8] - A recent landslide at Freeport McMoRan's Grasberg mine in Indonesia has raised global copper prices and sparked supply chain concerns, as this mine accounts for approximately 3% of global copper supply [9][10] Nuclear Fusion Sector Developments - The nuclear fusion concept stocks collectively surged, with companies like Hezhong Intelligent and Farsen hitting the daily limit, and others like Shanghai Electric and Baoli Electric also seeing significant increases [10][11] - China Fusion Energy Co., known as the "national team" for controllable nuclear fusion, is focusing on overall design, technology verification, and digital R&D [14] Company Specifics - On September 25, the stock of Upwind New Materials surged to a limit of 20%, reaching a price of 132.1 CNY per share, with a total market value of 53.3 billion CNY [15][16] - The company recently completed a share transfer, changing its controlling shareholder to Zhiyuan Hengyue, with plans for a tender offer to acquire an additional 37% of shares at a price of 7.78 CNY per share [18]

Core Viewpoint - The capital increase plan by Amgen Pharmaceuticals (688373.SH) aims to raise 1.033 billion yuan by issuing 164 million shares at 6.3 yuan each, which will not only meet funding needs but also change the equity structure, making Nanjing Haiqing Pharmaceuticals the controlling shareholder with a 20% stake [1][2]. Group 1: Capital Increase and Shareholder Dynamics - The capital increase will address the company's funding requirements and alter the shareholder structure, with Haiqing Pharmaceuticals becoming the new controlling entity [1]. - The opposition from board member Zhao Yachao and Genie Pharma, the largest external shareholder, indicates significant internal conflicts regarding the capital increase [2][3]. - The actual control of Genie Pharma lies with Yang Zhi, who is also linked to Baio Weida, suggesting a complex web of interests that may influence the decision-making process [2][3]. Group 2: Strategic Implications of the Capital Injection - The capital injection is expected to cover operational cash flow needs for over two years, directly supporting the development and commercialization of key drug candidates like MRX-4, MRX-5, and MRX-8 [4][7]. - Amgen's core competitiveness is rooted in its well-structured pipeline, focusing on innovative antibiotics for drug-resistant infections, with a strong emphasis on research and international clinical trials [5][6]. - The partnership with Haiqing Pharmaceuticals is anticipated to enhance Amgen's operational capabilities, transitioning the company from a research-driven model to a more integrated research-production-sales approach [5][6][9]. Group 3: Future Growth and Market Position - The collaboration is expected to yield significant commercial benefits, with projected sales revenues of 260 million, 388 million, and 600 million yuan from 2026 to 2028, indicating a doubling of sales over three years [6][7]. - The integration of Haiqing's resources is likely to optimize production processes and reduce costs, enhancing overall efficiency [6][7]. - The capital increase and strategic partnership mark a pivotal moment for Amgen, potentially leading to a shift in valuation from pipeline-based to performance-based metrics [7][8][10].

Core Viewpoint - The largest shareholder of Amgen Pharmaceuticals, Genie Pharma, has initiated a strong counteraction by proposing the removal of the chairman and two other directors, while also publicly soliciting voting rights to oppose several resolutions at the upcoming shareholder meeting [1][3]. Group 1: Shareholder Actions - Genie Pharma voted against multiple resolutions, including a proposed capital increase, at the upcoming shareholder meeting scheduled for 2025 [1]. - Genie Pharma has proposed to remove ZHENGYU YUAN (袁征宇) and two other directors, citing their failure to fulfill their responsibilities and protect shareholder interests [3][11]. - The proposed new directors include individuals currently associated with BioVeda, a significant stakeholder in Genie Pharma [13]. Group 2: Financial Performance - Amgen Pharmaceuticals has reported significant financial losses since its inception, with cumulative losses exceeding 1.3 billion yuan from 2021 to 2024 [3]. - The company's revenue has shown growth, reaching 130 million yuan in 2024, but net profit losses have also increased, with losses of 441 million yuan reported for the same year [3]. - The company's cash flow from operations has been negative for several consecutive years, indicating ongoing financial distress [3][6]. Group 3: Corporate Governance Issues - Genie Pharma has raised concerns about the management's capabilities, stating that the company is at risk of delisting due to its high debt ratio of approximately 60% and a significant decline in net assets since its IPO [6]. - The company has faced delays in its IPO fundraising projects, which has adversely affected its operational performance [6][7]. - There are allegations of poor judgment regarding strategic partnerships, particularly with Haiqing Pharmaceuticals, which has faced regulatory penalties [8][9][10].

Core Viewpoint - The largest shareholder of Amgen Pharmaceuticals, Genie Pharma, has initiated a strong counteraction by proposing the removal of the chairman and three directors, while also publicly soliciting voting rights to oppose several resolutions at the upcoming shareholder meeting [2][6]. Group 1: Shareholder Actions - Genie Pharma voted against multiple resolutions at the extraordinary general meeting scheduled for 2025, including a proposed capital increase [2]. - Genie Pharma has proposed to remove ZHENGYU YUAN (the current chairman and general manager) and three other directors, while nominating three new candidates for the board [2][6]. - The company has been without a controlling shareholder or actual controller since its listing in August 2022, with Genie Pharma and Amgen Hong Kong being the two largest shareholders [2][17]. Group 2: Financial Performance - Amgen Pharmaceuticals has faced significant financial challenges, with net cash flow from operating activities showing negative figures from 2022 to mid-2025, totaling -2.4 billion, -3.29 billion, -4.47 billion, and -1.21 billion respectively [6]. - The company's revenue has increased over the years, but net profit losses have also expanded, with cumulative losses exceeding 1.3 billion from 2021 to 2024 [6]. - As of June 2025, the company's asset-liability ratio reached approximately 60%, and its net assets have decreased by 74.19% since its listing [9]. Group 3: Governance Issues - Genie Pharma criticized ZHENGYU YUAN for failing to fulfill his responsibilities, leading to long-term losses and the risk of delisting [6][9]. - The company has experienced significant delays in the progress of its IPO fundraising projects, which has adversely affected its operations [10]. - There are concerns regarding the strategic investment choices made by the company, particularly in relation to its collaboration with Haiqing Pharmaceuticals, which has faced regulatory penalties [12][14].