证券代码：000963 证券简称：华东医药 公告编号：2026-005 华东医药股份有限公司 关于全资子公司收到上诉案件受理通知书的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 特别提示： 1、案件所处的诉讼（仲裁）阶段：二审已受理，尚未开庭审理； 2、上市公司所处的当事人地位：上诉人（一审原告）； 一、本次诉讼的基本情况 因侵害发明专利权纠纷，中美华东将青海珠峰冬虫夏草原料有限 公司、青海珠峰冬虫夏草药业有限公司、杭州华东武林大药房有限公 1 / 3 司三名被告诉至浙江省高级人民法院，详见公司于 2024 年 01 月 03 日在《证券时报》《中国证券报》《上海证券报》及巨潮资讯网 （www.cninfo.com.cn）上披露的《关于全资子公司收到浙江省高级 人民法院受理案件通知书的公告》（公告编号：2024-001）。 2025 年 12 月，中美华东收到浙江省高级人民法院送达的《民事 判决书》（2023）浙知民初 3 号，一审判决如下：驳回中美华东的全 部诉讼请求。案件受理费 598,732 元，由中美华东负担。详见公司于 2025 年 12 月 ...

证券日报网讯2月26日，华东医药（000963）在互动平台回答投资者提问时表示，关于HDM1005，公司 基于前沿技术和患者需求，已启动包括口服剂型在内的不同给药途径的探索性研究，目前正进行早期评 估，相关进展将按规定及时披露。公司始终将创新作为核心战略，研发聚焦于具有差异化和临床价值的 领域。 ...

截至2026年2月26日 13:57，中证医药及医疗器械创新指数(931484)成分股方面涨跌互现，新和成领涨 3.63%，兴齐眼药上涨2.61%，爱博医疗上涨2.28%；惠泰医疗领跌。医疗创新ETF(516820)最新报价0.36 元。 从资金净流入方面来看，医疗创新ETF近3天获得连续资金净流入，最高单日获得617.32万元净流入， 合计"吸金"1269.71万元，日均净流入达423.24万元。（数据来源：Wind） 医疗创新ETF紧密跟踪中证医药及医疗器械创新指数，中证医药及医疗器械创新指数从医药卫生行业的 上市公司中，选取30只盈利能力较好且具备一定成长性和研发创新能力的上市公司证券作为指数样本， 以反映兼具盈利性与成长性的医药及医疗器械上市公司证券的整体表现。 数据显示，截至2026年1月30日，中证医药及医疗器械创新指数(931484)前十大权重股分别为药明康 德、迈瑞医疗、恒瑞医药、爱尔眼科、片仔癀、新和成、华东医药、康龙化成、艾力斯、甘李药业，前 十大权重股合计占比63.9%。 风险提示：基金有风险，投资需谨慎。基金管理人承诺以诚实信用、勤勉尽责的原则管理和运用基金资 产，但不保证本基金一定盈 ...

与此同时，曾经的"抗衰明星"超声炮热度锐减过半，玻尿酸则在价格战的泥潭中稳守"顶流"地位。当合 规壁垒与技术迭代加速重塑市场，医美行业的"马太效应"正在以一种近乎残酷的方式上演，而减重与脱 发治疗正成为资本竞逐的下一个新大陆。 再生填充材料狂飙后的断层：463%增长与56%下降的"冰与火" 近日，医美平台美呗发布的《2025医美消费榜》显示，再生填充材料成为"年度MVP"，2025年销售额 同比增长93.40%，成为连续三年狂飙的"热门选手"。 在整个赛道狂奔的同时，各个品牌2025年销售额的增速却出现分化：臻爱塑菲以463%的强势增长排名 第一；艾维岚同比增长78.71%，稳扎稳打；伊妍仕的市场受到挤压，同比下降56%。 每经记者｜陈星 每经编辑｜黄博文 2025年的中国医美市场，在喧嚣中迎来了一个微妙的分水岭。 美呗平台最新数据显示，连续三年狂飙的再生填充材料赛道，在2025年销售额整体增长93.40%的光鲜 之下，还出现了内部断层：爱美客旗下的"臻爱塑菲"以463%的增速强势领跑，而昔日"少女针"王者华 东医药的"伊妍仕"却同比下降56%。 成都高新米兰柏羽医学美容医院皮肤科技术院长、副主任医师陈双瑜表 ...

Core Viewpoint - The article emphasizes the rising importance of biomanufacturing as a strategic and innovative field that disrupts traditional production methods, presenting it as a new growth point for optimizing industrial structure and transforming economic models [1]. Group 1: Current Status and Trends - The "2025 China Synthetic Biomanufacturing Industry Development White Paper" was officially released on August 1, highlighting the current state and trends of biomanufacturing [1]. - The report analyzes the global biomanufacturing industry, including key platform facilities and a comparative study of the US and China in this sector [7]. Group 2: Policy Landscape - The white paper outlines major domestic and international policies affecting biomanufacturing from 2024 to 2025, providing insights into regulatory frameworks [7]. Group 3: Industry Map and Applications - It presents a comprehensive map of the Chinese biomanufacturing industry and identifies key application areas, including pharmaceuticals, food, personal care, agriculture, chemicals, materials, and energy [7]. Group 4: Key Enterprises - The report selects ten leading enterprises in the Chinese biomanufacturing sector and details the strategic directions of 15 listed companies in synthetic biology [7][8]. Group 5: Investment and Challenges - The document discusses the investment landscape in synthetic biology from 2024 to mid-2025 and addresses the challenges faced by the biomanufacturing industry in China, along with proposed countermeasures [7].

Core Insights - The medical consumables supply chain SPD sector experienced a decline of 0.7% compared to the previous trading day, with Zhejiang Zhenyuan leading the drop [1] - The Shanghai Composite Index closed at 4134.02, up 0.05%, while the Shenzhen Component Index closed at 14283.0, up 0.86% [1] Sector Performance - The following companies in the medical consumables supply chain SPD sector showed varied performance: - RunDa Medical (603108) closed at 16.39, up 1.24% with a trading volume of 202,700 shares and a transaction value of 331 million yuan - JianMo Information (605186) closed at 22.28, up 0.22% with a trading volume of 27,300 shares and a transaction value of 60.93 million yuan - YingTe Group (000411) closed at 12.15, up 0.08% with a trading volume of 54,500 shares and a transaction value of 66.11 million yuan - Other companies like Langma Information (300288) and Guoyao Yizhi (000028) saw slight declines of 0.14% and 0.15% respectively [1] Capital Flow - On the same day, the medical consumables supply chain SPD sector saw a net outflow of 85.57 million yuan from institutional investors, while retail investors contributed a net inflow of 79.17 million yuan [2] - The capital flow for specific companies included: - RunDa Medical had a net inflow of 35.06 million yuan from institutional investors, while retail investors had a net outflow of 27.57 million yuan [3] - Zhejiang Zhenyuan experienced a net outflow of 0.82 million yuan from institutional investors, but a net inflow of 4.14 million yuan from retail investors [3]

Core Viewpoint - The report from Guolian Minsheng Securities highlights the synergistic effects of small nucleic acid drugs and GLP-1 class drugs in the weight loss sector, suggesting they could become a "golden duo" for weight management [1][4]. Group 1: Drug Efficacy and Development - Arrowhead has reported promising initial weight loss results from two small nucleic acid drugs targeting INHBE and ALK7, with ARO-INHBE showing an average fat reduction of 9.9% and liver fat reduction of up to 38.6%, alongside a 3.6% increase in lean tissue [1]. - ARO-ALK7 demonstrated a dose-dependent average reduction of ALK7 mRNA by 88%, confirming the TRiM platform's ability to inhibit fat cell gene expression [1]. - Wave Life's WVE-007 targeting liver INHBE showed a 9.4% reduction in visceral fat and a 4.5% overall fat reduction after three months, with a 3.2% increase in lean body mass [3]. Group 2: Market Trends and Collaborations - Major pharmaceutical companies are increasingly investing in small nucleic acid drugs, with Eli Lilly committing $1.2 billion in collaboration with Saint Inbiotech for RNAi candidate drug development for metabolic diseases [3]. - Eli Lilly also invested $1 billion in HAYA's lncRNA platform for obesity and related metabolic disease treatments, while Novo Nordisk partnered with Replicate Bioscience for a $550 million project targeting obesity and type 2 diabetes [3]. - The speed of Chinese pharmaceutical companies in developing small nucleic acid drugs for weight loss is nearly on par with international counterparts, with several companies like Hengrui Medicine and Innovent Biologics actively pursuing this area [5]. Group 3: Investment Recommendations - The report suggests focusing on companies involved in small nucleic acid weight loss targets, including Hengrui Medicine, Chengdu Xian Dao, China National Pharmaceutical Group, East China Pharmaceutical, and others [6].

Group 1 - The company is currently repurchasing and canceling a portion of restricted stocks from the "2022 Restricted Stock Incentive Plan" [1] - Future plans regarding stock repurchase will be announced in accordance with information disclosure regulations [1]

Group 1: Market Overview - The global sales of GLP-1 drugs have surpassed Merck's Keytruda, with Eli Lilly's Tirzepatide generating $36.5 billion and Novo Nordisk's Semaglutide achieving $36.1 billion in 2025 [1] - The sales of Tirzepatide's weight loss indication increased by 175% year-on-year, while the diabetes indication grew by 99% [1] - The potential patient market for weight loss is significantly large, indicating a strong demand for GLP-1 drugs [1] Group 2: Company Developments - Several domestic companies, including Innovent Biologics, Jiangsu Hengrui Medicine, Tonghua Dongbao, and East China Pharmaceutical, are actively developing GLP-1 drugs to meet weight loss market demands [2] - Innovent Biologics' GLP-1 weight loss drug, Sema, has been approved for sale in China, contributing to the company's revenue growth, which is expected to exceed 10 billion yuan in 2025 [3] - Hengrui Medicine is developing HRS9531, which shows promising results in weight loss and blood sugar control, while also improving cardiovascular and renal risk factors [4] Group 3: Competitive Strategies - Companies are adopting differentiated strategies in drug development, such as creating oral formulations, extending drug half-lives, and innovating sales models [5] - Hengrui Medicine is focusing on developing a GLP-1/GIP dual receptor agonist, which aims to enhance efficacy and safety [5] - Tonghua Dongbao is also working on a GLP-1/GIP dual receptor agonist, with clinical trials progressing smoothly [5] Group 4: Research and Development Focus - Innovent Biologics is expanding its research pipeline to include long-acting, oral, and multi-target projects, aiming to provide more effective treatment options [6] - East China Pharmaceutical is developing an oral small molecule GLP-1 drug, with successful completion of all subject enrollments for its clinical phase III study in weight management [6]

Group 1 - The SPD sector of the medical consumables supply chain increased by 0.24% compared to the previous trading day, with HeFu China leading the gains [1] - The Shanghai Composite Index closed at 4075.92, down 0.64%, while the Shenzhen Component Index closed at 13952.71, down 1.44% [1] - HeFu China saw a closing price of 19.69, with a rise of 6.72% and a trading volume of 699,400 shares, amounting to a transaction value of 1.354 billion yuan [1] Group 2 - The SPD sector experienced a net outflow of 8.4667 million yuan from institutional funds, while retail funds saw a net outflow of 7.3756 million yuan [2] - The top individual stocks in terms of net inflow included HeFu China with a net inflow of 109 million yuan from institutional investors [3] - The stock with the highest retail net inflow was HeFu China, despite a significant net outflow from institutional and retail investors [3]