Core Viewpoint - The article emphasizes China's dominant position in the global pharmaceutical supply chain, particularly in the production of Active Pharmaceutical Ingredients (APIs) and Key Starting Materials (KSMs), which poses a significant asymmetric threat to U.S. national security [4][5]. Group 1: China's Dominance in Pharmaceutical Supply Chain - China holds a near-monopoly in the production of various pharmaceutical raw materials, with over 90% of global antibiotic intermediates supplied by China [18]. - Approximately 70%-80% of global vitamin production capacity is controlled by China, making it a critical player in the pharmaceutical industry [19]. - China's low-cost, high-output chemical manufacturing capabilities create significant barriers for competitors, allowing it to define prices and capacities in the market [21]. Group 2: Impact of Geopolitical Tensions - The U.S.-China trade tensions have led to concerns about the dependency of the U.S. on Chinese pharmaceutical supplies, which could lead to drug shortages in critical situations [9][10]. - The article illustrates a hypothetical scenario where geopolitical tensions could disrupt the supply of essential medications, highlighting the risks of "asymmetric interdependence" [7][9]. - The ongoing drug shortage issues in the U.S. are exacerbated by the complex global supply chain, where many active ingredients are sourced from China [10][11]. Group 3: Historical Context and Strategic Decisions - The article discusses the historical context of the pharmaceutical industry's shift, where Western companies outsourced low-margin API production to lower-cost countries, primarily China, while retaining high-margin R&D and marketing functions [23][24]. - This outsourcing has led to a significant loss of industrial capability in the West, as the foundational skills and infrastructure for API production have diminished [32]. Group 4: Challenges for India as an Alternative - India, often referred to as the "world's pharmacy," lacks the complete supply chain necessary for API production, relying heavily on Chinese intermediates [36][38]. - Despite efforts to establish a domestic API supply chain, India's progress is hindered by infrastructure challenges and the dominance of Chinese suppliers [37][39]. Group 5: Future Outlook and Strategic Recommendations - The article suggests that China is transitioning from merely being a low-cost producer to becoming a leader in technology and standards within the pharmaceutical industry [43]. - As geopolitical tensions rise, the need for China to innovate in green technologies and maintain its competitive edge in the pharmaceutical supply chain becomes critical [55][56]. - The future of the pharmaceutical industry will focus on balancing efficiency and safety, with the ability to provide cost-effective and safe drugs being a key determinant of success [58].

转自：前瞻产业研究院 以下数据及分析来自于前瞻产业研究院医药研发外包(CRO)研究小组发布的《中国医药研发外包（CRO） 行业市场前瞻与投资战略规划分析报告》。 行业主要上市公司：目前国内CRO行业主要的上市公司有药明康德(603259.SH)、康龙化成(300759.SZ)、泰 格医药(300347.SZ)、凯莱英(002821.SZ)、昭衍新药(603127.SH)、九洲药业(603456.SH)、皓元医药 (688131.SH)、博腾股份(300363.SZ)、成都先导(688222.SH)、药石科技(300725.SZ)等。 1、"十五"到"十五五"：中国CRO行业政策聚焦 作为支撑医药创新的战略新兴产业，CRO是我国从医药大国迈向医药强国的关键力量。从"十五"到"十五 五"，我国从生物医药行业逐步聚焦到CRO专项领域，持续完善政策体系。"十五"将生物医药置于重要位 置，强调结构调整;"十一五"列为重点发展领域，支持产业集群;"十二五"提升至战略地位，明确支持CRO等 专业服务;"十三五"纳入战略性新兴产业，出台专项政策;"十四五"定位为生物医药高质量发展的"关键基础 设施";"十五五"则从单纯鼓励创 ...

智通财经获悉，1月22日，由中欧基金葛兰与赵磊共同管理的中欧医疗健康混合披露2025年四季报。截至2025年12 月末，葛兰旗下在管基金总规模由去年三季度末的435.44亿元降至353.89亿元。目前，葛兰在管3只公募基金，分 别是中欧医疗健康、中欧医疗创新、中欧明睿新起点混合，其中规模最大的产品是中欧医疗健康。报告期内，中 欧医疗健康混合基金A类份额净值增长率为-14.81%，同期业绩比较基准收益率为-8.21%；基金C 类份额净值增长 率为-14.98%，同期业绩比较基准收益率为-8.21%。 持仓方面，中欧医疗健康的前十大重仓股依次为：药明康德(603259.SH)、恒瑞医药(600276.SH)、康龙化成 (300759.SZ)、泰格医药(300347.SZ)、百利天恒(688506.SH)、凯莱英(002821.SZ)、信立泰(002294.SZ)、海思科 (002653.SZ)、科伦药业(002422.SZ)、百济神州-U(688235.SH)。其中，海思科、泰格医药获增持，科伦药业、信立 泰等多只个股遭减仓。 | | | ○ 中欧医疗健康混合A 2025年4季度股票投资明细 | | | | | ...

1月22日，由中欧基金葛兰与赵磊共同管理的中欧医疗健康混合披露2025年四季报。截至2025年12月末，葛兰旗下 在管基金总规模由去年三季度末的435.44亿元降至353.89亿元。目前，葛兰在管3只公募基金，分别是中欧医疗健 康、中欧医疗创新、中欧明睿新起点混合，其中规模最大的产品是中欧医疗健康。报告期内，中欧医疗健康混合 基金A类份额净值增长率为-14.81%，同期业绩比较基准收益率为-8.21%；基金C 类份额净值增长率为-14.98%，同 期业绩比较基准收益率为-8.21%。 持仓方面，中欧医疗健康的前十大重仓股依次为：药明康德(603259.SH)、恒瑞医药(600276.SH)、康龙化成 (300759.SZ)、泰格医药(300347.SZ)、百利天恒(688506.SH)、凯莱英(002821.SZ)、信立泰(002294.SZ)、海思科 (002653.SZ)、科伦药业(002422.SZ)、百济神州-U(688235.SH)。其中，海思科、泰格医药获增持，科伦药业、信立 泰等多只个股遭减仓。 | | | ○ 中欧医疗健康混合A 2025年4季度股票投资明细 | | | | | 来源:天天基金 ...

转自：前瞻产业研究院 以下数据及分析来自于前瞻产业研究院医药研发外包(CRO)研究小组发布的《中国医药研发外包（CRO）行 业市场前瞻与投资战略规划分析报告》。 行业主要上市公司：目前国内CRO行业主要的上市公司有药明康德(603259.SH)、康龙化成(300759.SZ)、泰 格医药(300347.SZ)、凯莱英(002821.SZ)、昭衍新药(603127.SH)、九洲药业(603456.SH)、皓元医药 (688131.SH)、博腾股份(300363.SZ)、成都先导(688222.SH)、药石科技(300725.SZ)等。 本文核心数据：CRO产业市场规模 行业概况 2、CRO行业产业链剖析 中国 CRO 产业链贯穿药品全生命周期，可以分为三个阶段。研发阶段CRO，含临床前药物发现、化合物合 成等基础研发与临床阶段试验等;生产阶段CMO/CDMO，覆盖化学原料药、生物药、化学药制剂等不同类型 药物的生产环节;销售阶段CSO，以渠道管理为核心，配套推广营销与市场监测，服务企业、科研机构、医 1、CRO的定义 合同研究组织 (Contract Research Organization, CRO) 是指 ...

Group 1 - Norges Bank reduced its stake in Kintor Pharmaceutical (06821) by 110,000 shares at a price of HKD 88.1971 per share, totaling approximately HKD 9.7017 million [1][3] - After the reduction, Norges Bank's latest holding is 4.1326 million shares, representing a stake of 14.99% [1][3]

Group 1 - Norges Bank reduced its stake in Kelaiying (002821) by 110,000 shares at a price of HKD 88.1971 per share, totaling approximately HKD 9.7017 million [1] - After the reduction, Norges Bank's latest holding is 4.1326 million shares, representing a holding percentage of 14.99% [1]

Group 1 - Norges Bank reduced its stake in Kintor Pharmaceutical (06821) by 110,000 shares at a price of HKD 88.1971 per share, totaling approximately HKD 9.7017 million [1] - After the reduction, Norges Bank's latest holding is 4.1326 million shares, representing a holding percentage of 14.99% [1]

Investment Rating - The report maintains an "Outperform" rating for several companies, including Jiangsu Heng Rui Medicine, Hansoh Pharmaceutical Group, 3SBio, Sichuan Kelun Pharmaceutical, and Jiangsu Nhwa Pharmaceutical [6][7]. Core Insights - The annual J.P. Morgan Healthcare Conference concluded successfully, with positive information from global pharmaceutical companies, including new pipeline disclosures and major deals. The report highlights the high prosperity in the innovative drug sector and recommends continuous investment in innovative drugs and the industry chain [25][26]. - The A-Shares pharmaceutical sector underperformed the market in the third week of January 2026, with the Shanghai Composite Index falling by 0.4% and the SW Pharmaceutical and Biological sector declining by 0.7% [8][27]. - The Hong Kong stock pharmaceutical sector performed in line with the market, while the U.S. pharmaceutical sector underperformed. The Hang Seng Healthcare index increased by 2.4%, and the S&P 500 Healthcare Select Sector decreased by 1.1% [28]. Summary by Sections Section 1: Continuous Recommendation of Innovative Drugs and Industry Chain - The report emphasizes the high prosperity of innovative drugs and maintains overweight ratings for key pharmaceutical companies. It also recommends Biopharma/Biotech companies with promising pipelines and volume increases, as well as CXO and upstream companies benefiting from innovation [6][25]. Section 2: A-Shares Pharmaceutical Sector Performance - In the third week of January 2026, the A-Shares pharmaceutical sector's performance was ranked 17th among Shenwan primary industries, with a decline of 0.7%. The medical service sub-sector showed a positive performance of +3.3% [8][12][27]. Section 3: Hong Kong and U.S. Pharmaceutical Sector Performance - The Hong Kong pharmaceutical sector performed similarly to the market, while the U.S. sector underperformed. Notable gainers in the U.S. included MODERNA (+22%) and QUEST DIAGNOSTICS (+9%), while major decliners included BIOGEN (-12%) and BOSTON SCIENTIFIC (-10%) [28].

Group 1 - The core viewpoint of the news is that Kailaiying has shown significant trading activity and financial performance, with a notable increase in shareholder numbers and revenue growth [1][2]. Group 2 - On January 16, Kailaiying's stock rose by 0.78%, with a trading volume of 639 million yuan. The financing buy amount was 36.72 million yuan, while the financing repayment was 56.27 million yuan, resulting in a net financing outflow of 19.55 million yuan [1]. - As of January 16, the total balance of margin trading for Kailaiying was 853 million yuan, with a financing balance of 849 million yuan, accounting for 2.41% of the circulating market value, which is above the 50th percentile level over the past year [1]. - In terms of securities lending, on January 16, Kailaiying repaid 2,400 shares and sold 100 shares, with a selling amount of 10,700 yuan. The remaining securities lending volume was 45,900 shares, with a balance of 4.92 million yuan, also above the 50th percentile level over the past year [1]. Group 3 - As of September 30, Kailaiying had 60,100 shareholders, an increase of 45.37% compared to the previous period. The average circulating shares per person remained at 0 shares [2]. - For the period from January to September 2025, Kailaiying achieved operating revenue of 4.63 billion yuan, a year-on-year increase of 11.82%, and a net profit attributable to shareholders of 800 million yuan, up 12.66% year-on-year [2]. - Since its A-share listing, Kailaiying has distributed a total of 2.405 billion yuan in dividends, with 1.701 billion yuan distributed over the past three years [2]. Group 4 - As of September 30, 2025, among the top ten circulating shareholders of Kailaiying, the largest shareholder was Central European Medical Health Mixed A, holding 16.3189 million shares, an increase of 34,600 shares compared to the previous period [2]. - Hong Kong Central Clearing Limited ranked as the fourth largest circulating shareholder, holding 13.2877 million shares, an increase of 626,400 shares [2]. - The sixth largest circulating shareholder, Huabao Zhongzheng Medical ETF, held 5.6467 million shares, a decrease of 1 million shares compared to the previous period [2].