证券代码：688065 证券简称：凯赛生物 公告编号：2025-048 上海凯赛生物技术股份有限公司 关于召开 2025 年半年度业绩说明会的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 会议召开时间：2025 年 09 月 25 日（星期四）14:00-15:00 会 议 召 开 地 点 ： 上 海 证 券 交 易 所 上 证 路 演 中 心 （ 网 址 ： https://roadshow.sseinfo.com/） 会议召开方式：上证路演中心网络互动 一、说明会类型 本次投资者说明会以网络互动形式召开，公司将针对 2025 年半年度的经营 成果及财务指标的具体情况与投资者进行互动交流和沟通，在信息披露允许的范 围内就投资者普遍关注的问题进行回答。 二、说明会召开的时间、地点 （一） 会议召开时间：2025 年 09 月 25 日（星期四）14:00-15:00 （二）会议召开地点：上证路演中心 （三）会议召开方式：上证路演中心网络互动 三、参加人员 董事长兼总裁：XIUCAI LIU(刘修才)博士 ...

Industry Overview - The chemical sector's overall performance ranked 12th this week (2025/09/08-2025/09/12) with a change of 2.36%, outperforming the Shanghai Composite Index by 0.83 percentage points and the ChiNext Index by 0.25 percentage points [2][3] - The chemical industry is expected to continue its differentiated trend in 2025, with recommendations to focus on synthetic biology, pesticides, chromatography media, sugar substitutes, vitamins, light hydrocarbon chemicals, COC polymers, and MDI [2][3] Synthetic Biology - The arrival of a pivotal moment in synthetic biology is anticipated, driven by energy structure adjustments that may disrupt fossil-based materials, favoring low-energy products [2] - Traditional chemical companies are expected to compete on energy consumption and carbon tax costs, with successful firms leveraging green energy alternatives and integrated advantages to reduce costs [2] - Companies like Kasei Bio and Huaheng Bio are highlighted as leaders in the synthetic biology sector [2] Refrigerants - The implementation of quota policies is expected to lead to a high-growth cycle for third-generation refrigerants, with supply entering a "quota + continuous reduction" phase starting in 2024 [3] - The demand for refrigerants is projected to grow due to the development of heat pumps, cold chain markets, and the expansion of the air conditioning market in Southeast Asia [3] - Companies such as Juhua Co., Sanmei Co., Haohua Technology, and Yonghe Co. are positioned to benefit from this trend [3] Electronic Specialty Gases - Electronic specialty gases are critical to the electronics industry, characterized by high technical barriers and added value [4] - The domestic market faces a contradiction between rapid upgrades in wafer manufacturing and insufficient high-end electronic specialty gas capacity [4] - Companies like Jinhong Gas, Huate Gas, and China Shipbuilding Gas are expected to capitalize on the growing demand driven by semiconductors, displays, and photovoltaics [4] Light Hydrocarbon Chemicals - The trend towards lighter raw materials in the global olefin industry is noted, with a shift from heavy naphtha to lighter alkanes like ethane and propane [5] - Light hydrocarbon chemicals are recognized for their low carbon emissions, low energy consumption, and low water usage, aligning with global carbon neutrality goals [5] - Satellite Chemical is recommended as a key player in the light hydrocarbon chemical sector [5] COC Polymers - The industrialization of COC/COP (cyclic olefin copolymer) is accelerating in China, driven by domestic companies achieving breakthroughs and the shift of downstream industries to China [6] - COC/COP materials are increasingly used in high-end applications, with domestic firms expected to overcome supply-side bottlenecks [6] - Akolai is identified as a company to watch in the COC polymer production segment [6] MDI Market - The MDI market is characterized by oligopoly, with demand steadily increasing due to the expansion of polyurethane applications [9] - The market is currently experiencing price stabilization at low levels, but profitability remains strong [9] - Wanhu Chemical is highlighted as a key player in the polyurethane sector, benefiting from the anticipated improvement in the MDI supply landscape [9] Potash Fertilizer - Potash fertilizer prices are expected to rebound as the industry enters a destocking phase, with supply constraints due to Canpotex withdrawing new quotes and Nutrien announcing production cuts [7][8] - The demand for potash is projected to rise as farmers increase planting intentions, influenced by rising grain prices [8] - Companies such as Yara International, Salt Lake Potash, and Cangge Mining are noted as leading firms in the potash sector [8] Weekly Price Tracking - The top five price increases this week included liquid chlorine (21.69%), acrylic acid (5.66%), and trichloroethylene (4.44%) [10] - The top five price decreases included butyl rubber (-11.25%), NYMEX natural gas futures (-4.33%), and DMF (-3.68%) [10] Supply-Side Tracking - A total of 162 chemical enterprises had their production capacities affected this week, with 7 new repairs and 11 restarts reported [11]

Core Insights - The chemical new materials industry is evolving towards high-performance materials, green low-carbon production, and intelligent manufacturing processes, with bio-based materials emerging as a prominent sector [2] - A collaboration between Kunlun Engineering and Puyang Shengtong Juyuan New Materials has led to the development of bio-based polycarbonate (PC), marking a significant advancement in domestic production capabilities [2][3] - The project aims to replace traditional bisphenol A with renewable isosorbide, resulting in a product with high transparency and potential applications in various high-value markets [2][5] Group 1: Bio-based Materials Development - Bio-based materials, such as bio-based nylon and LCP, have gained significant market attention, with companies like Haizheng Bio-materials and Kasei Biotech leading the way [2] - The bio-based PC production facility is set to be the largest in China, with a successful launch planned for February 2025, filling a domestic gap in the market [2][3] - The unique molecular structure of the new bio-based PC allows for high surface hardness and excellent optical properties, making it suitable for applications in optical lenses and automotive parts [2][5] Group 2: Technological Challenges - Key technological challenges include designing high-activity catalytic systems, enhancing the melt polycondensation process, and achieving precise control over copolymer structures [3] - The industry is also exploring alternatives such as bio-based bisphenol A and bio-based dimethyl carbonate (DMC) to replace traditional monomers [5][6] - The development of high-performance catalysts for DMC synthesis has been achieved, indicating progress towards fully bio-based polycarbonate production [5] Group 3: Market Dynamics - The current production capacity of polycarbonate in China is 3.81 million tons, with a self-sufficiency rate of 75%, but high-end products still rely heavily on imports [6] - The bio-based polycarbonate is not a direct substitute for traditional PC but represents an upgrade towards high-end applications, addressing the current market's low-end surplus [6] - Companies like Covestro and Mitsubishi Chemical are leading the global market in bio-based PC innovations, with plans for mass production of 100% bio-based products by 2025 [6][7] Group 4: Strategic Directions - China National Petroleum Corporation (CNPC) is focusing on new materials and biotechnology as key development areas, emphasizing a transition towards clean energy and sustainable materials [7][8] - The strategic plan includes advancing the development of high-end polyolefins, specialty fibers, and high-performance synthetic rubbers [8] - CNPC aims to leverage its existing oil and gas infrastructure to support the growth of renewable energy and new material sectors [8]

Investment Rating - The report maintains a "Positive" rating for the chemical industry [6][12]. Core Insights - The macroeconomic judgment indicates that non-OPEC countries are expected to lead an increase in oil production, with a significant overall supply growth anticipated. Global GDP growth is projected to remain at 2.8%, with stable oil demand, although the growth rate may slow due to tariff policies [6][7]. - The expectation of a Federal Reserve interest rate cut is likely to boost demand during the peak season of September and October. Additionally, the leakage incident of GFL R32 in India may enhance China's export opportunities [6][12]. - The report highlights the ongoing investigation into anti-dumping practices against imported semiconductor chips from the U.S., which may benefit domestic semiconductor materials [6][12]. Summary by Sections Macroeconomic Analysis - Oil supply is expected to increase significantly, driven by non-OPEC production, while demand remains stable despite potential slowdowns due to tariffs. Geopolitical factors, including U.S.-China tariff relief and the Russia-Ukraine situation, are influencing oil prices [6][7]. - Coal prices are anticipated to stabilize at a low level, and natural gas export facilities in the U.S. may accelerate, leading to lower import costs [6][7]. Chemical Sector Configuration - The report suggests a strategic focus on four areas: textile and apparel chain, agricultural chemicals, export chain, and sectors benefiting from "de-involution" policies. Specific companies are recommended for investment based on their market positions and growth potential [6][12]. Key Material Focus - Emphasis is placed on the importance of self-sufficiency in key materials, particularly in semiconductor and panel materials, with specific companies highlighted for their potential in these sectors [6][12]. Price Trends - Recent data indicates fluctuations in various chemical prices, with PTA prices down by 0.3% and MEG down by 2.0%. The report notes that the overall industrial product PPI has shown a year-on-year decline of 2.9% [12][13][16]. Company Valuations - A detailed valuation table is provided, showcasing various companies in the agricultural chemicals and chemical sectors, with ratings ranging from "Buy" to "Increase" based on their market performance and projected earnings [20].

Investment Rating - The industry investment rating is "Overweight" [1] Core Insights - The report highlights the ongoing global biotechnology revolution, emphasizing its integration into economic and social development to address major challenges such as health, climate change, and food security. The National Development and Reform Commission has issued the "14th Five-Year Plan for Biological Economy Development," indicating a trillion-yuan market potential in the biological economy [3][4]. Market Performance - The synthetic biology index increased by 2.01% to 1218.13 during the week of September 1-5, 2025, outperforming the Shanghai Composite Index by 3.19% and underperforming the ChiNext Index by 0.34% [4][20]. - The top five performing companies in the synthetic biology sector during the same week were: - Haizheng Biomaterials (+17%) - BeiGene (+15%) - Kelun Pharmaceutical (+11%) - Health元 (+9%) - Yuanli Technology (+6%) [21][22]. Company Developments - Fuxiang Pharmaceutical has established a wholly-owned subsidiary in Singapore to expand its microbial protein business, aiming for an annual production capacity of 20,000 tons of microbial protein and 50,000 tons of amino acid water-soluble fertilizer [26]. - Kasei (Taiyuan) Biomaterials Co., Ltd. has announced a project for the annual production of 90,000 tons of bio-based polyamide, with existing production capabilities in bio-based products [26]. - Zhejiang Zhenyuan has officially launched its industrialization base for synthetic biology, which includes a facility for the production of histidine and other bio-based products [29]. - Honeywell has partnered with Syzygy Plasmonics to initiate the world's first electrified biogas-to-sustainable aviation fuel (SAF) project in Uruguay, expected to produce over 350,000 gallons of SAF annually [29][30]. Industry Standards - The national standard GB/T 46256-2025 for bio-based materials and products has been released, which will take effect on March 1, 2026. This standard establishes a comprehensive identity certification system for bio-based materials, promoting industry standardization and regulation [10].

Core Viewpoint - During the "14th Five-Year Plan" period, China's composite materials industry is transforming towards green, low-carbon, and sustainable development, supported by national policies promoting renewable raw materials and composite technology research [1]. Group 1: Industry Trends - The application and promotion of green composite materials are accelerating in various sectors, including automotive, aerospace, shipping, rail transportation, sports and leisure products, and infrastructure [1]. - Companies like Kaisi Bio have made significant breakthroughs in the development and downstream applications of green composite materials in recent years [1]. Group 2: Challenges - The green composite materials industry faces challenges such as unstable raw material sources, immature processes, high costs, and difficulties in recycling [1]. Group 3: Event Details - The 4th Green Composite Materials Forum (GCMF 2025) will be held on November 30 in Hangzhou, Zhejiang, focusing on three main themes: resin and fiber, composite technology, and downstream applications [1][2]. - The agenda includes discussions on industry development, global research trends, key preparation technologies for bamboo-based composites, and advanced composite technologies [2][3].

Group 1 - The core viewpoint of the news is that Kaisa Bio has seen a stock price increase of 5.1%, reaching 54.77 CNY per share, with a trading volume of 257 million CNY and a turnover rate of 0.82%, resulting in a total market capitalization of 39.505 billion CNY [1] - Kaisa Bio, established on November 24, 2000, and listed on August 12, 2020, focuses on the research, production, and sales of new bio-based materials using synthetic biology and biomanufacturing technologies [1] - The company's main revenue sources are long-chain dicarboxylic acids (89.98%), other products (6.08%), and bio-based polyamides (3.95%) [1] Group 2 - Among Kaisa Bio's top ten circulating shareholders, Huaxia Fund's ETF (588000) increased its holdings by 3.4%, amounting to 19.8524 million shares, with an estimated floating profit of approximately 52.8074 million CNY [2] - The Huaxia ETF was established on September 28, 2020, with a current scale of 83.343 billion CNY, achieving a year-to-date return of 27.97% and a one-year return of 89.57% [2] - The fund manager, Rong Ying, has a tenure of 9 years and 310 days, with a total asset scale of 138.288 billion CNY, while Zhao Zongting has a tenure of 8 years and 147 days, managing 389.148 billion CNY [3]

Group 1 - The core viewpoint of the articles emphasizes the importance of ensuring the safe operation of special equipment during major events in Urumqi City, Xinjiang, through collaborative efforts among various departments [1][2] - The Urumqi Market Supervision Administration has formed a service guidance team that includes emergency management, commerce and industry, industrial parks, and urban management departments to provide technical support and safety inspections [1] - The service guidance team conducted thorough inspections of escalators, elevators, and gas filling stations, ensuring compliance with safety regulations and enhancing the safety awareness of personnel [1] Group 2 - The Urumqi Market Supervision Administration plans to continue improving the "guidance-correction-follow-up" closed-loop mechanism to ensure the safety of special equipment during major events [2]

Industry Overview - The chemical sector's overall performance ranked 11th this week (2025/08/25-2025/08/29) with a fluctuation of 1.11%, positioned in the upper-middle of the market. The Shanghai Composite Index fluctuated by 0.84%, while the ChiNext Index saw a fluctuation of 7.74%. The Shenwan Chemical sector outperformed the Shanghai Composite by 0.27 percentage points but underperformed the ChiNext by 6.63 percentage points [1][2]. Key Industry Insights - The chemical industry is expected to continue its differentiated trend in 2025, with recommendations to focus on synthetic biology, pesticides, chromatography media, sweeteners, vitamins, light hydrocarbon chemicals, COC polymers, and MDI [2]. Synthetic Biology - A pivotal moment for synthetic biology is anticipated, driven by energy structure adjustments. Traditional chemical companies will face competition based on energy consumption and carbon tax costs. Companies that utilize green energy alternatives and scale advantages are likely to reduce energy costs and expand into larger overseas markets. The demand for bio-based materials is expected to surge, leading to potential profitability and valuation increases. Key companies to watch include Kasei Bio and Huaheng Bio [2]. Refrigerants - The implementation of quota policies is expected to usher in a high-growth cycle for third-generation refrigerants. Starting in 2024, the supply of these refrigerants will enter a "quota + continuous reduction" phase, while second-generation refrigerants will see accelerated reductions. The demand for refrigerants is projected to grow steadily due to the development of heat pumps, cold chain markets, and the expansion of the air conditioning market in Southeast Asia. Companies with a high quota share in refrigerants are likely to benefit from the ongoing supply-demand gap. Relevant companies include Juhua Co., Sanmei Co., Haohua Technology, and Yonghe Co. [3][4]. Electronic Specialty Gases - Electronic specialty gases are critical to the electronics industry and represent a core aspect of domestic industrial chain localization. The domestic market is experiencing rapid upgrades in wafer manufacturing, leading to a mismatch between the demand for high-end electronic specialty gases and the insufficient domestic production capacity. Companies that can establish high-end production capacity and possess substantial technical reserves are expected to gain a competitive edge. Key players include Jinhong Gas, Huate Gas, and China Shipbuilding Gas [4][5]. Light Hydrocarbon Chemicals - The trend towards light raw materials in the global olefin industry has been significant over the past decade, with a shift from heavy naphtha to lighter low-carbon alkanes like ethane and propane. This transition is characterized by shorter processes, higher yields, and lower costs. Light hydrocarbon chemicals are also aligned with global low-carbon and energy-saving initiatives. The leading companies in this sector are expected to see their valuations reassessed positively [5]. COC Polymers - The industrialization process of COC/COP (cyclic olefin copolymer) is accelerating in China, driven by domestic companies achieving breakthroughs after years of research. The shift of downstream industries, such as consumer electronics and new energy vehicles, to domestic production has heightened the urgency for local alternatives. The market for COC/COP remains constrained by supply-side bottlenecks, but domestic companies are poised to break through and expand market opportunities. Notable companies include Akerley [6]. MDI Market Dynamics - The MDI market is characterized by oligopolistic supply dynamics, with demand remaining stable due to the expansion of polyurethane applications. The global MDI production capacity is concentrated among eight manufacturers, with five major companies accounting for 90.85% of total capacity. Despite current price pressures, MDI is expected to maintain profitability, and the supply landscape is likely to improve as demand recovers. Key companies to monitor include Wanhua Chemical [9]. Price Tracking - The top five price increases this week included NYMEX natural gas (11.08%), bisphenol A (2.99%), PX (2.86%), refrigerant R32 (2.56%), and butadiene (2.08%). Conversely, the largest price declines were seen in liquid chlorine (-25.86%), urea (-3.45%), TDI (-3.33%), toluene (-3.18%), and pure benzene (-2.70%) [10]. Supply Side Tracking - This week, 153 chemical companies reported changes in production capacity, with six new maintenance activities and four restarts noted [11].

Overview of Continuous Supervision - The continuous supervision work includes reviewing company governance documents, financial management, internal controls, and fundraising management [1][2][3] Key Findings - No major issues were found during the continuous supervision period [2] Major Risk Factors - Core Competitiveness Risk: The company relies on advanced biomanufacturing techniques for producing new materials, and the retention of skilled personnel is crucial for maintaining competitive advantage [2][3] - Operational Risk: The company faces risks related to raw material and energy costs, which are influenced by market fluctuations [4][5] - Financial Risk: The company has a good credit status but may face challenges in accounts receivable management and potential foreign exchange losses [8][9] Financial Performance - Revenue for the first half of 2025 reached 167,076.79 million, a 15.68% increase from the previous year [15] - Net profit attributable to shareholders was 30,866.71 million, reflecting a 24.74% increase [15] - Total assets increased by 25.23% to 2,382,118.27 million [15] Core Competitiveness - The company has developed a comprehensive production chain for biobased polyamides and maintains a strong patent portfolio with 516 patents [16][17] - The company emphasizes technological innovation and has a stable management team with extensive experience in R&D [16][17] R&D Investment - R&D expenditure for the first half of 2025 was 12,319.85 million, a 23.13% increase compared to the previous year [22][23] - The proportion of R&D investment to revenue increased by 0.44 percentage points, indicating a commitment to maintaining competitive advantage [23] Business Development - The company is expanding its production capacity and has initiated several projects, including a 50,000-ton biobased hexamethylenediamine project [5][20] - The company has established partnerships with major firms and is recognized as a leading supplier in the biobased materials market [21] Environmental and Safety Considerations - The company’s biomanufacturing processes are designed to minimize waste and reduce carbon emissions, contributing to sustainability goals [18][19] - Safety management systems are in place to mitigate risks associated with production processes [21] Market Position - The company is a leading player in the biobased materials sector, with a strong brand and customer base, facilitating further market expansion [21]