包菜，一年四季皆可见，便宜量大，平凡到人们经常甚至想不起来吃它。但其实，包菜的营养十分可圈可点。 十字花科蔬菜，抗氧化 包菜和西蓝花、花菜等一样，都属于典型的十字花科芸薹属蔬菜，自然也就具有十字花科蔬菜独特的营养优势——富含抗氧化物硫代葡萄糖苷。这类植物化 合物在研究中不仅表现出了强大的抗氧化效果，还被发现具有一定的潜在抗癌作用，有助于降低肺癌、结肠癌、乳腺癌等癌症发生风险。 低卡高纤高维C，冬日优选 包菜农残高？ 不用太过于担心 关于包菜，很多朋友担心其农药残留，民间流传着"包菜长一层叶子喷一次农药"的说法。事实上，这种担心没有太大必要。蔬菜生长过程中绝大多数都需要 施用农药，但并没有证据显示包菜比其他蔬菜的农药残留更高。 包菜的热量很低，仅24千卡/100克，比起根茎类、鲜豆类蔬菜，其热量优势相当明显，同时也比菜薹（28千卡/100克）、菠菜（28千卡/100克）、红苋菜 （35千卡/100克）等低卡的绿叶蔬菜更低些。 而且，包菜中不可溶性膳食纤维有1克/100克，还有较丰富的可溶性膳食纤维，前者可以增加饱腹感、促进肠道蠕动，后者可以作为肠道益生菌群的食物， 帮助调节肠道菌群稳态。 另外，包菜的维生素C含 ...

腹型肥胖易诱发心血管问题 专家：肥胖人群需遵医嘱精准减重 王玲特别提醒，对于心血管事件高风险或已患有心血管疾病的肥胖人群，需在专业医生指导下，积极管 理体重达到心血管获益，不建议通过极端节食、高强度运动等不合理方式盲目减重。(完) "科学减重健康轻盈"肥胖症科普沙龙近日在广州举行。该活动以书籍《国人体重管理百科》为核心载 体，助力公众建立科学的体重管理认知。 随着我国居民生活水平提升，肥胖症日益成为威胁公众健康的重大因素。超重和肥胖是多种慢性疾病的 重要致病因素。 暨南大学附属第一医院胃肠外科与减重中心学科带头人王存川介绍道：肥胖症是慢性疾病中的独立病 种，也是心血管疾病在内的多种慢性疾病的重要致病因素，影响到全身多系统，已成为重大公共卫生问 题。 王存川也强调，每位肥胖症患者的体重基数、身体基础、生活环境、运动能力均存在差异，肥胖症患者 需要结合自身情况，在专业医生指导下，遵循医嘱科学减重。 中山大学附属第一医院内分泌科副主任医师刘娟进一步解释，"结合自身情况"并非简单参考体重数字， 而是要通过全面的医学检查，如身体成分分析等，明确肥胖类型、代谢水平及潜在健康风险；医生会根 据评估结果，为患者制定适合自己的 ...

Summary of Esperion Therapeutics Conference Call Company Overview - **Company**: Esperion Therapeutics (NasdaqGM:ESPR) - **Event**: Key opinion leader-investor event focused on statin intolerance and cardiovascular health - **Date**: November 11, 2025 Key Points Financial Performance - **Q3 Total Revenue**: $87.3 million, representing a nearly 70% year-on-year growth [3] - **Q3 US Net Product Sales**: $40.7 million, indicating a 31% year-on-year growth [3] - **Retail Prescription Equivalents**: 9% increase quarter-over-quarter [4] Product Development and Market Position - **Nexletol and Nexlizet**: Outpacing the broader lipid-lowering market and exceeding growth of other non-statin therapies [4] - **Statin Intolerance**: Approximately 50% of patients starting statin therapy discontinue or have significant gaps in treatment within two years, highlighting a market opportunity for Nexletol and Nexlizet [5] - **Direct-to-Consumer Advertising**: Launched on platforms like Disney+ and Hulu, achieving over 6 million impressions since October [7] Clinical Insights - **Statin Intolerance Definition**: Up to 30% of US adults experience some degree of statin intolerance, which can lead to non-adherence and increased cardiovascular risk [10][12] - **Bempedoic Acid**: Developed to address statin intolerance, it is a pro-drug that targets the liver, avoiding muscle-related side effects associated with statins [15] - **Clinical Trials**: Bempedoic acid has shown significant LDL cholesterol reduction and hsCRP lowering, with the Clear Outcomes trial being the only outcomes study in statin-intolerant patients [19][22] Market Access and Awareness - **Medicare and Commercial Approval Rates**: 87% for Medicare and 86% for commercial plans, indicating improved access for patients [8] - **Patient Copays**: Average copays are $29 and $36 for a 30-day supply, reflecting growing payer confidence [8] - **Awareness Challenges**: There is a significant gap in awareness among healthcare professionals regarding non-statin therapies, which affects adoption rates [52][56] Physician Perspectives - **Patient Characteristics**: Females and older individuals are at higher risk for statin intolerance, and many patients are unwilling to start statin therapy due to perceived side effects [12][14] - **Combination Therapy**: There is a growing trend towards using combination therapies to achieve LDL targets, especially in high-risk patients [40][41] - **Imaging Tools**: Physicians are increasingly using imaging to educate patients about their cardiovascular risk and the importance of LDL-lowering therapies [48] Future Outlook - **Guideline Updates**: Recent ESC guidelines emphasize the importance of non-statin therapies, with bempedoic acid receiving high recommendations for statin-intolerant patients [22] - **Educational Commitment**: Esperion is dedicated to educating both healthcare providers and patients about statin intolerance and available alternatives [23] Additional Insights - **Patient Education**: There is a need for better education regarding the risks of high LDL cholesterol and the importance of treatment adherence [56] - **Market Potential**: The potential market for bempedoic acid is significant, especially among primary care populations and patients with diabetes [58] This summary encapsulates the key insights and data presented during the conference call, highlighting Esperion Therapeutics' performance, product positioning, and the broader implications for cardiovascular health management.

Core Viewpoints - Semaglutide is recognized as a significant medical breakthrough with potential applications beyond obesity and sleep apnea, including treatment for various diseases such as heart failure, arthritis, Alzheimer's, and cancer [2][4]. - The drug's ability to improve cardiovascular metabolic health suggests far-reaching benefits that could revolutionize cardiovascular care [2][4]. Group 1: Medical Applications - Semaglutide shows potential in treating multiple diseases, including heart failure, arthritis, Alzheimer's, and cancer, by improving overall health and potentially delaying aging [4]. - The Select trial involved over 17,600 patients aged 45 and above with obesity or overweight and cardiovascular disease risk, demonstrating a significantly lower all-cause mortality rate in the semaglutide group compared to the placebo group [4]. Group 2: Efficacy and Safety - In patients taking semaglutide, the mortality rate from COVID-19 was 2.6%, compared to 3.1% in the placebo group, indicating a significant reduction in death rates despite similar infection risks [6]. - Semaglutide effectively reduces the risk of severe cardiovascular events and alleviates heart failure symptoms, regardless of weight loss [6]. Group 3: Drug Mechanism and Usage - Semaglutide, marketed under the brand names Wegovy and Ozempic, mimics the GLP-1 hormone to induce satiety and reduce hunger, administered via injection [6]. - Experts caution that semaglutide is not a panacea and should not replace healthy diet and exercise, emphasizing the importance of medical supervision to avoid potential side effects [6]. Group 4: Future Research and Implications - Ongoing research is exploring the potential of semaglutide and similar drugs in combating age-related diseases, indicating a promising future for longevity biotechnology in global health systems [6]. - The era of semaglutide in medicine is just beginning, with its comprehensive impact still requiring further study and observation [6].

Core Insights - Cardiovascular disease is the leading cause of death globally, with over 75% of deaths occurring in low- and middle-income countries, including Vietnam [1] - Approximately 30% of Vietnamese adults suffer from dyslipidemia, a significant risk factor for atherosclerotic cardiovascular disease [1] - Statins, particularly high-intensity statins like atorvastatin, are crucial in reducing the risk of heart attacks, strokes, and cardiovascular deaths [2] Company Initiatives - Viatris has organized scientific events to reaffirm its commitment to addressing cardiovascular challenges and improving public health in Vietnam [4] - A significant event was the conference titled "Atorvastatin: 25 Years Advancing Cardiovascular Health," which attracted over 400 healthcare professionals [5] - Viatris emphasizes community outreach through initiatives like the "Don't Miss A Beat" seminar and participation in running events to promote cardiovascular health [8][10] Scientific Contributions - Atorvastatin has been recognized for its effectiveness in preventing cardiovascular events across diverse patient populations, supported by extensive clinical evidence [6] - The company continues to leverage its scientific expertise and diverse medicine portfolio to improve access to high-quality medicines for Vietnamese patients [11][12] Commitment to Health - Viatris aims to raise awareness about cardiovascular health and is committed to partnering with healthcare professionals for a healthier Vietnam [10] - The company’s mission is to empower healthier living by providing access to high-quality medicines for approximately 1 billion patients annually [12]

Group 1 - The core idea emphasizes the health benefits of walking after meals, particularly in reducing blood sugar and triglyceride levels [4][6][9] - Research indicates that sitting after meals can lead to a significant increase in postprandial blood sugar, with sitting causing a 2.75 times greater increase compared to walking [4] - Engaging in light physical activity, such as walking, can significantly lower post-meal triglyceride levels, with reductions of about one-third observed in studies [7] Group 2 - Walking after meals aids digestion and can help with weight management, as it promotes food movement through the digestive system and alleviates feelings of fullness [9] - For individuals aged 65 and older, specific considerations for walking include choosing appropriate routes, maintaining stable walking pace, being mindful of weather conditions, and planning walking intensity [10][11][12][13][14]

Core Viewpoint - Peanuts are a nutritious food source that offers various health benefits, including high-quality protein, healthy fats, and essential vitamins and minerals, making them a valuable addition to a balanced diet [2][3][7][10][13]. Nutritional Composition - Peanuts contain 574 kcal, 24.8g of protein, 44.3g of fat, and 21.7g of carbohydrates per 100g [2]. - The fat composition includes 19.8% saturated fat, 38.6% monounsaturated fat, and 38.6% polyunsaturated fat, indicating a high proportion of "good" fats [7][8]. Health Benefits - Peanuts are a good source of plant-based protein, containing all eight essential amino acids, making them suitable for vegetarians and those looking to increase plant protein intake [3]. - They are rich in B vitamins, particularly B1 and niacin, which support energy metabolism and maintain healthy skin and nervous system [8][10]. - Peanuts contain antioxidants like resveratrol and flavonoids, which help reduce oxidative stress and may contribute to longevity [10][13]. - Regular consumption of peanuts is associated with a lower risk of cardiovascular diseases and improved blood sugar control due to their low glycemic index (GI) of 14 [15][16][18]. Consumption Guidelines - The recommended daily intake of peanuts is 25-35g, depending on other dietary sources of protein and fats [22]. - Different cooking methods can affect the nutritional value of peanuts, with raw and boiled options being healthier compared to fried [23][24]. Special Considerations - Individuals with peanut allergies should avoid peanuts entirely due to the risk of severe allergic reactions [25]. - Overweight individuals should monitor their intake due to the high caloric content of peanuts [26]. - Young children should consume peanuts in forms that reduce choking hazards, such as peanut butter [28]. - Those with metabolic disorders should consult healthcare professionals for appropriate consumption levels [29].

Core Insights - Peanuts, despite their high fat content, are often recommended in healthy diets due to their rich nutritional profile and health benefits [1][16] Nutritional Composition - Peanuts contain 574 kcal of energy, 24.8g of protein, 44.3g of fat, and 21.7g of carbohydrates per 100g [3] - They are a good source of plant-based protein, comparable to legumes, providing all eight essential amino acids [5][6] - The fat composition is primarily unsaturated, with 38.6% being monounsaturated and 38.6% polyunsaturated fats, which are beneficial for heart health [8][10] Health Benefits - Peanuts are rich in B vitamins, including 0.72mg of vitamin B1 and 17.9mg of niacin per 100g, which support energy metabolism and nervous system health [11][12] - They contain powerful antioxidants like resveratrol and flavonoids, which help reduce oxidative stress and may delay aging [13][18] - Regular consumption of peanuts is associated with a lower risk of cardiovascular diseases and stroke, particularly in older adults [19] - Peanuts have a low glycemic index (GI) of 14, making them suitable for blood sugar management [20][22] Consumption Guidelines - Recommended daily intake is 25-35g for those not consuming other legumes or nuts, and 15-20g if other sources are included [25] - Cooking methods affect nutritional content; raw or low-temperature roasted peanuts retain more nutrients compared to fried ones [27] Caution for Specific Groups - Individuals with peanut allergies should avoid peanuts entirely due to severe allergic reactions [30] - Overweight individuals should monitor their intake due to high caloric density [33] - Young children should consume peanuts in forms that reduce choking risks, such as peanut butter [34] - Those with metabolic disorders should consult healthcare providers for appropriate consumption levels [35]

Core Viewpoint - The article discusses the historical significance, medicinal properties, and market potential of Huaihua (Sophora japonica), highlighting its dual role as both a food and a medicine, and its growing demand in various sectors [1][11]. Historical and Cultural Significance - Huaihua has been recognized in Chinese culture since ancient times, with references in texts like "Shan Hai Jing" [1]. - It is associated with auspicious meanings and is used in traditional customs for its protective qualities [1]. Medicinal Properties - Huaihua is recognized as a "dual-use" substance, serving both as a food and a medicine since its inclusion in the 2002 list by the Ministry of Health [1]. - The active components in Huaihua include triterpenoid saponins, flavonoids, and polysaccharides, which contribute to its health benefits [5]. Health Benefits - **Antioxidant Effects**: Huaihua contains flavonoids that help eliminate free radicals and reduce oxidative stress, which is linked to chronic inflammation [6]. - **Cardiovascular Health**: Active compounds in Huaihua can reduce platelet aggregation, thereby lowering the risk of cardiovascular diseases [7]. - **Anti-Glycation**: Huaihua extracts can inhibit the formation of advanced glycation end products (AGEs), which are harmful compounds associated with diabetes complications [9]. - **Brain Health**: Studies indicate that Huaihua extracts can suppress inflammatory responses in the brain, potentially reducing neuronal damage [10]. Market Potential - The global market for Huaihua extracts is projected to grow from $20.2 million in 2025 to $37.9 million by 2033, with a compound annual growth rate (CAGR) of 8.2% [11]. - The increasing applications of Huaihua in pharmaceuticals, food, and cosmetics are driving market demand [11].