2019年6月13日，上海证券交易所科创板正式开板。六年过去，科创板一直坚守"硬科技"定位，在服务 国家创新驱动发展战略、助力企业成长、推动科技创新等方面交出了一份亮眼的成绩单。截至2025年6 月13日，科创板上市公司已达588家，为资本市场高水平科技自立自强和新质生产力发展贡献了积极力 量。 在业绩表现上，科创板上市公司营收持续走高，部分企业年度收入突破千亿元大关。在研发投入方面， 科创板上市公司更是不遗余力，展现出非凡的创新活力。2022年至2024年，全市场科创板上市公司的研 发投入分别为1373.97亿元、1581.52亿元和1679.89亿元。此外，科创板在首次公开募股和并购重组方面 不断深化改革。站在新的历史节点，科创板将持续书写新篇章。 市场活力充分展现 在业绩表现上，近三年科创板上市公司营收持续走高，2022年至2024年，营业收入分别达到13489.92亿 元、14204.62亿元和14260.71亿元，展现出稳健的上升态势。其中，部分企业更是凭借强劲的经营实 力，年度收入突破千亿元大关，成为行业内的佼佼者，为科创板的业绩增色不少。 以晶科能源为例，其近三年业绩一路高歌猛进，2022年营业 ...

| 行业类 V | 当前价 # | 涨跌幅 * | 成交量 ÷ | | 总市值 = 年初至今 = | 0 | | --- | --- | --- | --- | --- | --- | --- | | 全球航空业E ... | 21.87 | -0.55 (-2.45%) | 62.05万股 | 6889.05万 | -13.73% | 를 … | | US JETS | | | | | | | | 区域银行ET ... | 56.56 | ↓ -1.22 (-2.11%) | 240.97万股 | 47.20亿 | -5.66% | ( ) *** | | us KRE | | | | | | | | 银行业ETF - ... | 53.16 | -1.05 (-1.94%) | 11.08万股 | 41.15亿 | -3.48% | () *** | | us KBE | | | | | | | | 金融业ETF --- | 50.09 | -0.92 (-1.79%) | 509.25万股 | 557.47 亿 | +4.01% | U " | | us XLF | | | | | | | | 半导体E ...

Fundraising Overview - The company successfully raised a net amount of RMB 26,911.62 million after deducting issuance costs from the initial public offering of 21,666,668 shares [1] - The funds have been fully received and verified by Tianzhi International Accounting Firm [1] Fund Management and Usage - The company has established a special account for the management and storage of the raised funds, in compliance with relevant regulations and internal management policies [1] - A tripartite supervision agreement has been signed with the sponsoring institution and the bank to ensure proper management of the funds [1] Fund Account Status - The company has detailed the status of its fundraising special accounts, including various projects such as online marketing network construction, offline service network upgrades, and research center construction [1] - Specific accounts have been opened at banks like Ping An Bank and Industrial and Commercial Bank of China for different projects [1] Account Cancellation - The company has canceled a fundraising special account with a balance of RMB 3,962.27, transferring the remaining funds to its general account for daily operational liquidity [2] - The cancellation of the account has been completed, and the corresponding regulatory agreement has also been terminated [2]

Core Viewpoint - A research team from the University of Washington and the Brotman Baty Institute has developed a "claw machine"-like technology for the rapid and automated classification of embryoid bodies, providing critical support for studying individual differences in early embryonic development and the mechanisms of genetic diseases [1][2]. Group 1: Technology Development - The newly developed automated sorting system integrates microscopy, cameras, and robotic micro-manipulation technology, featuring a detachable micro-structure called "micro-raft" for the growth of embryoid bodies [2]. - The system operates like a high-precision "claw machine," autonomously scanning large arrays of "micro-rafts," identifying the characteristics of embryoid bodies, and physically sorting them based on preset criteria, enhancing precision and efficiency [2]. Group 2: Research Implications - The embryoid body model can reveal early developmental abnormalities similar to human diseases, previously clarifying how Huntington's disease manifests genetic traits in early embryos, even before traditional clinical symptoms appear [2]. - The new platform can sort unique embryoid bodies exhibiting subtle phenotypic differences, maintaining sample integrity and paving the way for subsequent live-cell imaging or genetic sequencing [2].

Group 1 - Suzhou is enhancing its employment-friendly city construction to promote high-quality development and employment expansion, having been recognized as the best city for employment promotion for five consecutive years [1] - The city has established 348 local employment service stations, helping over 9,000 individuals from disadvantaged groups find jobs [2] - The local government is focusing on providing precise employment services, including matching job seekers with local recruitment needs and offering free accommodation for out-of-town job seekers [2] Group 2 - Major projects in Suzhou are expected to create over 30,000 new jobs, with more than 200 significant projects being completed since the beginning of 2024 [4] - The city is integrating industry, education, and research to enhance employment opportunities along the industrial chain, including the development of a low-altitude economy and tailored skill training programs [4] - A new training model combining job needs, skill training, and employment services is being implemented to cultivate skilled workers in emerging sectors like drone technology [4][6] Group 3 - Suzhou is launching a summer skill training program to utilize the teaching downtime in schools, aiming to enhance the practical skills of young individuals [6] - The focus on improving employment skills is seen as essential for maintaining the dynamism of the local economy and ensuring the continuous evolution of industry and talent [6]

Group 1: Event Overview - The 11th China (Shanghai) International Technology Import and Export Fair was held from June 11 to June 13, focusing on "hard technology" and future industries, showcasing nearly a hundred breakthrough achievements in fields like brain-machine interfaces, embodied intelligence, quantum technology, and synthetic biology [1][2] - The event highlighted significant innovations such as the world's first sound tweezers single-cell sorting technology and the debut of self-developed lunar soil fiber technology and equipment, indicating a promising future for the technology industry [1][2] Group 2: Innovations in Lunar Technology - East China University of Science and Technology showcased the "in-situ preparation of lunar soil fiber modular equipment," which is included in China's lunar base construction plan, utilizing lunar soil from the Chang'e 5 mission to create fibers for lunar base construction [2] - The technology aims to convert lunar soil into high-performance fibers, enabling local resource utilization and meeting the material performance needs for lunar base construction [2] Group 3: Advancements in Biotechnology - The Soundpen CB system developed by Oubino Biotechnology employs non-contact, label-free acoustic tweezers to manipulate cells with precision, significantly enhancing experimental efficiency by minimizing cell damage [3] - The event also featured brain-machine interface technologies that allow patients with central nervous system injuries to control exoskeletons for rehabilitation, demonstrating practical applications in hospitals and rehabilitation centers [5][6] Group 4: Robotics and Automation - The fair showcased various robots, including a six-legged robot designed for Antarctic research, which can assist in transporting materials and ensuring safety by detecting cracks in the ice [3][4] - Nanjing University presented a multimodal interactive robot capable of intelligent dialogue and music synchronization, which is already in mass production and available in North America [4] Group 5: 3D Printing in Pharmaceuticals - The company San Diego demonstrated its 3D printing technology for pharmaceuticals, achieving continuous and large-scale production of printed drugs, with an annual capacity of 75 million to 300 million tablets [6] - Lepu Medical introduced the MemoSorb biodegradable occluder series, the first of its kind globally, providing innovative treatment solutions for congenital heart disease and stroke prevention [6]

就A股市场来看，A股上半年共有50家企业实现首发上市，上 市企业以中小规模企业为主，合计筹资超过371亿元，IPO数 量和筹资额实现双增长，均同比上升14%。 作者：姜鑫 封图：图虫创意 "2025上半年，未有IPO破发，IPO平均首日回报达到220%，与2024上半年的136%相比，同比大幅上升。" 2025年6月12日，在《中国内地和香港IPO市场》报告（下称"报告"）发布现场，安永北京主管合伙人杨淑娟如是介绍了上半年A股IPO（首次公开募 股）发行情况。 报告显示，2025年上半年，中国内地和香港地区IPO活动在全球中的占比上升。其中，香港IPO活动表现抢眼，筹资额占全球总筹资额的24%，与A股 合计占全球总筹资额的33%。同时，得益于宁德时代等大型IPO推动，港交所以140亿美元募资规模登顶全球。 全球市场IPO数量和融资规模 A股IPO平均首日回报达到220% 就A股市场来看，A股上半年共有50家企业实现首发上市，上市企业以中小规模企业为主，合计筹资超过371亿元，IPO数量和筹资额实现双增长，均同 比上升14%。 报告显示，从行业来看，工业、科技和材料领域的IPO数量和筹资额分居前三位。汽车行业作 ...

Group 1: Global IPO Activity - In the first half of 2025, the proportion of IPO fundraising from mainland China and Hong Kong rose to 33% of the global total, with Hong Kong accounting for 24% of global fundraising [1][6] - The global IPO market is expected to see around 500 companies listed, with total fundraising of $57.5 billion, reflecting a 9% increase in fundraising despite an 11% decrease in the number of IPOs compared to the previous year [1] Group 2: A-Share Market Performance - A total of 50 companies went public in the A-share market in the first half of 2025, raising over 37.1 billion RMB, marking a 14% increase in both the number of IPOs and the total fundraising amount year-on-year [4] - The industrial, technology, and materials sectors led in both the number and amount of IPOs, with over 30% of the listed companies belonging to the automotive industry [4] Group 3: Regional Contributions to A-Share IPOs - The Yangtze River Delta and Pearl River Delta regions are the main contributors to A-share listings, with Jiangsu, Zhejiang, Guangdong, and Anhui being the top four provinces, collectively accounting for 90% of the total IPOs [5] - In terms of fundraising, Zhejiang, Guangdong, Jiangsu, Heilongjiang, and Anhui accounted for 78% of the total amount raised [5] Group 4: Hong Kong IPO Market Recovery - Approximately 40 companies are expected to go public in Hong Kong in the first half of 2025, raising around 108.7 billion HKD, with a 33% increase in the number of IPOs and a 711% increase in fundraising compared to the previous year [6] - The average fundraising amount for Hong Kong IPOs has increased more than fivefold year-on-year, making it the second-highest in the last decade, only after the same period in 2021 [6] Group 5: Focus on Technology and Innovation - The launch of the "Tech Company Special Line" in May 2025 indicates a shift in the Hong Kong market towards technology innovation, facilitating the listing of high-potential tech companies [7] - The A-share market is expected to adopt a "new normal" in IPO issuance, focusing on high-quality tech companies that meet listing criteria, with macroeconomic conditions and market funds influencing the IPO rhythm [8] Group 6: Future Outlook for IPO Markets - The North Exchange is becoming a key player in IPO applications, reflecting its support for specialized small and medium enterprises, with expectations for expansion into emerging industries like artificial intelligence and cultural creativity [8] - The enthusiasm for companies from the A-share market to list in Hong Kong is expected to continue, driven by the establishment of the "Tech Company Special Line" and the return of Chinese companies to the U.S. market [8]

Group 1 - In the first half of 2025, there were no IPOs that broke below their issue price, with an average first-day return of 220%, a significant increase from 136% in the same period of 2024 [2] - The report indicates that the IPO activities in mainland China and Hong Kong have increased their share of global IPOs, with Hong Kong accounting for 24% and A-shares for 33% of the total global fundraising [2][9] - The Hong Kong Stock Exchange topped the global fundraising scale with $14 billion, driven by large IPOs such as CATL [2][9] Group 2 - A total of 50 companies went public in the A-share market, raising over 37.1 billion yuan, marking a 14% increase in both the number of IPOs and the amount raised compared to the previous year [5] - The industrial, technology, and materials sectors led in both the number of IPOs and the amount raised, with over 30% of the IPOs in the automotive industry [5] - The average oversubscription rate for IPOs has significantly increased, reflecting heightened investor enthusiasm for new listings [5] Group 3 - The report highlights a trend of declining IPO queues, with only 28 companies filing for IPOs from January to May 2025, compared to just 2 in the same period last year [6] - The termination of IPOs is nearing its end, with 67 companies withdrawing their applications in 2025, a significant decrease from nearly 300 in the previous year [6][7] - The A-share IPO market is expected to focus more on technology-driven companies, with quality enterprises meeting listing conditions likely to proceed with their IPOs [8] Group 4 - The Hong Kong IPO market saw a surge, with approximately 40 companies expected to go public, raising around 10.87 billion HKD, representing a 33% increase in the number of IPOs and a 711% increase in the amount raised year-on-year [9] - The introduction of the "Tech Company Fast Track" in Hong Kong aims to facilitate the listing of technology and biotech companies, enhancing financing efficiency [12] - The report suggests that the IPO market in Hong Kong will continue to thrive due to the enthusiasm for A-share companies listing in Hong Kong and the return of Chinese companies listed abroad [15]

证券代码：301080 证券简称：百普赛斯 公告编号：2025-039 北京百普赛斯生物科技股份有限公司 监事会关于公司 2025 年股权激励计划授予激励对象名单（授予 日）的核查意见 本公司及监事会全体成员保证信息披露的内容真实、准确、完整，没有虚 假记载、误导性陈述或重大遗漏。 北京百普赛斯生物科技股份有限公司（以下简称"公司"）第二届监事会第十 七次会议于 2025 年 6 月 12 日在公司会议室召开，审议通过了《关于向 2025 年 限制性股票激励计划激励对象首次授予限制性股票的议案》《关于向 2025 年股 票增值权激励计划激励对象授予股票增值权的议案》。 公司监事会根据《中华人民共和国公司法》（以下简称"《公司法》"）、《中 华人民共和国证券法》（以下简称"《证券法》"）、《上市公司股权激励管理办 法》（以下简称"《管理办法》"）、《深圳证券交易所创业板股票上市规则》（以 下简称"《上市规则》"）等有关法律、法规和规范性文件的规定，对获授权益的 激励对象名单进行审核，发表核查意见如下： 本次授予的激励对象具备《公司法》《证券法》等法律、法规和规范性文件 以及《公司章程》规定的任职资格，符合《管理 ...