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获批FDA!全球首款非金属外周弹簧圈
思宇MedTech· 2025-06-27 09:07
思宇年度活动回顾: 首届全球眼科大会 | 首届全球骨科大会 | 首届全球心血管大会 | 首届全球医美科技大会 即将召开: 2025年7月17日,第二届全球医疗科技大会 2025年9月3-5日,第三届全球手术机器人大会 心未来 近日, 专注于血管栓塞技术 的创新型公司 Embolization 宣布,其研发的 基于 聚合物的 非金属弹簧圈 已获得美国食品药品监督管理局(FDA)510(k)市场准入认证。 该产品适用于 外周血管动静脉栓塞 ,标志着血管栓塞领域的一项技术进步。随着510(k)认证的获得, Embolization计划尽快启动其商业化进程。 血管栓塞是一种微创介入治疗技术,医生 通过导管将细小材料(如线圈、微粒或胶体)注入目标血管,达 到止血、阻断肿瘤供血或修复异常血管的目的 。 由于操作精确、恢复时间短、创伤小,该方法已成为手术的常见替代方案,尤其在 外周血管疾病治疗 中 广泛应用。 弹簧圈 是最常见的 机械性栓塞器材 ,其 经导管引导至目标血管后可发生脱离,随即嵌在血管腔上,进而 阻塞血液流动 。 弹簧圈 通常由铂金、镍钛合金、铬合金等金属材料制成 ,这些材料 具有良好的生物相容性 ,能够在体内 ...
FutureHouse 联合创始人:AI Scientist 不是“全自动化科研”
海外独角兽· 2025-06-26 12:25
编译:shiling 编辑:Siqi 海外独角兽原创编译 转载请注明 FutureHouse 是由 Google 前 CEO Eric Schmidt 资助创立的、专注于 AI for Science 方向的的 AI Lab, 团队的长期目标是打造可自主提出问题、规划实验、迭代假设的 AI 科学家 体系。 今年 5 月,FutureHouse 推出了四个 AI 科研 agent,分别是 Crow(通用智能体)、Falcon(自动化文 献综述智能体)、Owl(调研智能体)以及 Phoenix(实验智能体),这些 AI agent 可访问完整科学 文献全文,还具备信息质量评估能力,一个月后,FutureHouse 又宣布自己的 AI 系统 Robin 成功发 现了新药。 AI 推动生物科学 可以分为两层视角,一层视角是以 AlphaFold 3 、ESM3 到 Evo 2 等模型为代表,把 分子-细胞-系统的设计空间瞬间打开,另外一层则是 FutureHouse 在探索的科研自动化,agent 系统构 成的 AI Scientist 把实验室变成"黑灯实验室",进一步变成可编排的软件流水线。FutureHouse ...
Certara (CERT) FY Earnings Call Presentation
2025-06-25 11:12
Certara William F. Feehery, Ph.D. Chief Executive Officer William Blair 25th Annual Growth Stock Conference Wednesday, June 4th, 2025 Disclaimer Numerical figures in the presentation have been subject to rounding adjustments. Acc ordingly , numeric al f igures shown as tota ls in various tables may not be arithmetic aggregations of the figures that precede them. Trademarks and Service Marks The Certara design logo, "Certara," and our other registered or common law trademarks, service marks or trade names ap ...
市场消息:商船“Phoenix 15”在阿曼塞拉莱海岸附近沉没,船上20名船员被阿曼附近船只救起。
news flash· 2025-06-21 07:39
市场消息:商船"Phoenix 15"在阿曼塞拉莱海岸附近沉没,船上20名船员被阿曼附近船只救起。 ...
Ryman Hospitality Properties, Inc. Closes Acquisition of JW Marriott Phoenix Desert Ridge Resort & Spa
Globenewswire· 2025-06-10 20:15
Core Insights - Ryman Hospitality Properties, Inc. has successfully completed the acquisition of the JW Marriott Phoenix Desert Ridge Resort & Spa for approximately $865 million [1][2]. Company Overview - Ryman Hospitality Properties is a leading lodging and hospitality real estate investment trust specializing in upscale convention center resorts and entertainment experiences [3]. - The company's portfolio includes five of the top seven largest non-gaming convention center hotels in the U.S., with a total of 12,364 rooms and over 3 million square feet of meeting space [3]. Acquisition Details - The JW Marriott Desert Ridge is located on approximately 402 acres in Arizona and features 950 guest rooms, including 81 suites, and about 243,000 square feet of meeting and event space [2]. - The resort includes amenities such as a 28,000-square-foot spa, seven dining options, a 140,000-square-foot water amenity, and two golf courses [2]. - The property has undergone nearly $100 million in capital investments, including renovations and upgrades to various facilities [2].
澳洲三居室$172万流拍,女子“一见钟情”,最终$187万拿下!
Sou Hu Cai Jing· 2025-05-24 14:49
Core Insights - A 30-something professional woman purchased a Georgian-style home in South Yarra, Melbourne for AUD 1.875 million after it initially failed to sell at auction with a reserve price of AUD 1.85 million [1][3] - The property features three bedrooms, a luxurious bathroom, and a small backyard, and was listed between AUD 1.7 million and AUD 1.9 million [1][3] - In a separate auction in Footscray, a dilapidated three-bedroom house sold for AUD 720,000, with four bidders competing for the property, which had been vacant for years [5][8] Auction Details - The auction for the South Yarra property started at AUD 1.7 million, with the only registered bidder making a single bid of AUD 1.725 million before it was declared unsold [3] - The buyer, who recently moved from New Zealand, had been in contact with the real estate agent since the previous sales activity [3] - The Footscray property was listed with a price range of AUD 600,000 to AUD 660,000, with a reserve price of AUD 660,000 [5][8] Market Sentiment - The recent interest rate cut has restored confidence in the market, leading to increased consultation levels and positive market sentiment [10] - The first rate cut had initially sparked some activity, but subsequent elections distracted buyers; however, the second cut has prompted buyers to act quickly to avoid missing opportunities [10]
Ryman Hospitality Properties, Inc. Announces Closing of Upsized Common Stock Offering and Full Exercise of Underwriters' Over-Allotment Option
GlobeNewswire News Room· 2025-05-21 14:35
Core Viewpoint - Ryman Hospitality Properties, Inc. has successfully closed an upsized public offering of 2,990,000 shares of common stock, raising approximately $275 million to fund a portion of the acquisition of the JW Marriott Phoenix Desert Ridge Resort & Spa [1][3][4] Group 1: Offering Details - The shares were sold at a public price of $96.20 per share, including 390,000 shares from the underwriters' option exercised on May 20, 2025 [1] - The offering was managed by Morgan Stanley, BofA Securities, J.P. Morgan, and Wells Fargo Securities as joint book-running managers, with additional bookrunners including Deutsche Bank Securities and others [2] Group 2: Use of Proceeds - The net proceeds from the offering will be contributed to RHP Hotel Properties, LP, which will use the funds to cover part of the $865 million purchase price for the Desert Ridge Acquisition [3] - The remaining purchase price will be funded through cash on hand and proceeds from a private placement of $625 million in senior notes, expected to yield approximately $614 million after expenses [4] Group 3: Company Overview - Ryman Hospitality Properties, Inc. is a leading real estate investment trust specializing in upscale convention center resorts and entertainment experiences, managing a portfolio that includes five of the largest non-gaming convention center hotels in the U.S. [6] - The company also has a controlling interest in Opry Entertainment Group, which includes iconic country music brands and various entertainment venues [6]
长江基建举办股东周年大会 李泽鉅:对未来股价乐观 收购“不会志在必得”
Zhi Tong Cai Jing· 2025-05-21 12:53
李泽鉅表示,长江基建于2024年8月19日于伦敦证券交易所正式第二上市,伦敦第二上市亦有望为集团 未来进行重大收购增加融资渠道。然而,集团将继续坚持严格的财务审慎和纪律原则,并且绝不会 以"必须赢"的心态寻求收购,即"不会志在必得"。集团不断在世界各地寻求优质收购,但世界秩序和市 场仍然动荡,是否可以进行收购取决于许多因素。 针对未来收并购,他表示,集团去年完成了几项收购,这方面成绩还不错。截至2024年底,长江基建持 有现金约80亿港元,净负债与净总资本比率维持在7.8%的健康水平。集团处于非常有利的位置,可以 抓住不断增强的增长和收购机会。 他又回顾,去年长建收购多个项目,包括北爱尔兰配气网络Phoenix Energy、英国陆上风电场组合UK Renewables Energy,以及英国可再生能源资产组合Powerlink Renewable Assets,认为整体成绩不错。 日前,长江基建(01038)举行股东周年大会,主席李泽鉅表示,集团对业务前景感到审慎乐观。李泽鉅 表示,自2024年年初至今天,长建的股东总回报约28%,充分显示集团稳健的业务受到投资者持续支 持。各项回报指标均显示长建的业务持续 ...
“非典型”出海路,传音如何用“本地化创新”改写规则
3 6 Ke· 2025-05-20 02:41
Group 1 - The global smartphone market saw a 3% year-on-year increase in shipments in Q1 2025, with "second" overseas expansion becoming essential for many brands, particularly in Southeast Asia, Africa, and Latin America [1] - Transsion Holdings has maintained rapid growth, with over 200 million units shipped, ranking among the top three globally, and has been the largest smartphone supplier in Africa since 2017 [1][2] - Transsion's strategy focuses on "global localization," effectively covering a market of 4 billion people across Asia, Africa, and Latin America [1] Group 2 - Transsion has a strong presence in Africa, with a 51% market share in smartphone shipments in 2024, reflecting a 10% year-on-year growth [2][3] - The company has built a robust local sales and service network, ensuring quick market response and customer support through its independent after-sales brand, Carlcare [2] - Transsion's localized product development, tailored to African consumers' preferences, has solidified its market dominance [2][4] Group 3 - In 2024, Transsion achieved a 16% market share in Southeast Asia, with significant performance in the Philippines and Indonesia, driven by its Infinix brand targeting the gaming smartphone segment [5][7] - The company recorded a 40% growth rate in the Latin American smartphone market, securing the fourth position with shipments reaching 12.8 million units [7] - In the Middle East, Transsion ranked second in smartphone shipments with a 17% market share, growing by 9% year-on-year [7] Group 4 - Transsion's total revenue for 2024 reached 68.715 billion yuan, marking a year-on-year increase of over 10%, despite fluctuations in Q1 2025 due to high base effects and inventory adjustments [8] - The company has increased its R&D investment by 11.55% in 2024, focusing on core capabilities in imaging, AI, charging, and user experience [8][10] - Transsion's technological innovations, such as full-skin tone imaging and AI video editing, cater to diverse user needs in emerging markets [10] Group 5 - Transsion's multi-brand strategy, with TECNO, Infinix, and itel targeting different market segments, allows it to navigate industry cycles and capture structural opportunities [11][12] - The company has integrated mobile internet services with hardware, creating a localized content ecosystem, exemplified by its music streaming service Boomplay, which has over 94 million monthly active users [12] - Transsion's expansion into AI and smart hardware, including TWS earbuds and AI services, further enhances its market position and user engagement [13][15] Group 6 - Transsion's approach emphasizes deep market understanding and localized strategies, establishing a comprehensive ecosystem that includes smartphones, internet services, and smart devices [17] - The company's success is attributed to its ability to adapt technology to meet local demands, reinforcing its competitive edge in emerging markets [17]
Ryman Hospitality Properties, Inc. Announces Offering of 2,300,000 Shares of Common Stock
Globenewswire· 2025-05-19 20:26
NASHVILLE, Tenn., May 19, 2025 (GLOBE NEWSWIRE) -- Ryman Hospitality Properties, Inc. (NYSE: RHP) (the “Company”) today announced that it has commenced an underwritten registered public offering (the “Offering”) of 2,300,000 shares of its common stock, par value $0.01 per share. The Company expects to grant the underwriters a 30-day option to purchase up to 345,000 additional shares of common stock. The Company expects to contribute the net proceeds of the Offering to RHP Hotel Properties, LP (the “Operatin ...