Core Viewpoint - The article highlights the recent funding success of Beijing SuXin Technology Co., Ltd., which focuses on bioenzyme technology for efficient degradation and recycling of PET materials, addressing the global plastic pollution crisis [2][4]. Company Overview - Beijing SuXin Technology has completed pre-A and pre-A+ financing rounds totaling several tens of millions of RMB, aimed at advancing the construction and technological iteration of its ton-level bioenzyme-based PET recycling production line [2]. - The company has successfully operated a pilot production line with a capacity of one thousand tons, with plans to achieve a ton-level production line by the end of 2025 [4]. Technology and Innovation - SuXin Technology utilizes an AI-enhanced enzyme design platform and a large-scale enzyme library, achieving breakthroughs in acid resistance, stability, and catalytic efficiency, which significantly reduce industrial production difficulties and overall costs [2][3]. - The company aims to lower the cost of bio-based recycled PET to a level comparable to that of virgin PET within three to five years, potentially even lower in the long term [4]. Market Potential - SuXin Technology has provided sample products to leading companies in the automotive polyester filament sector and several international brands, with expectations to achieve monthly supply of one thousand tons within six months [4]. - The company anticipates annual revenue to exceed 100 million RMB by 2026, reflecting strong market demand and growth potential [4]. Environmental Impact - The funding round indicates strong confidence from the capital market in bioenzyme recycling technology, offering a new industrial path for plastic pollution management with significant environmental benefits and commercial value [4].

Core Viewpoint - The article discusses the recent inclusion of three Chinese biotechnology companies in the U.S. Entity List, highlighting the ongoing tensions in the biotechnology sector between the U.S. and China, particularly in relation to national security concerns and technological competition [2][3]. Group 1: U.S. Policy Developments - On September 12, the U.S. Department of Commerce's Bureau of Industry and Security (BIS) announced the addition of 23 Chinese entities to the Entity List due to actions deemed contrary to U.S. national security or foreign policy interests, including three from the biotechnology and life sciences sector [2]. - The entities listed will require export licenses for all items governed by the Export Administration Regulations (EAR), with a presumption of denial for such licenses, indicating a significant barrier for these companies in international trade [2]. Group 2: Companies Listed - The three biotechnology companies added to the Entity List are: 1. Beijing Tianyi Huiyuan Biotech, established in 2008, focuses on gene sequence detection, gene synthesis, gene editing, and protein expression vector assembly, serving various hospitals and research institutions [3]. 2. Beijing Tsingke Biotech Co., Ltd., founded in 2017, operates as a comprehensive gene synthesis platform, providing a range of services including gene synthesis, antibody proteins, and molecular reagents, and has attracted significant investment, including a B-round financing of 400 million RMB [4]. 3. Sangon Biotech (Shanghai) Co., Ltd., founded in 2003, offers over 20,000 products across seven categories, including DNA synthesis and sequencing, and has a global presence in 147 countries, recognized as a major player in the DNA synthesis market [5].

Core Viewpoint - The article emphasizes the development of non-grain biomass resources for energy and bio-based materials, highlighting the upcoming NFUCon 2025 forum aimed at discussing commercialization paths and technological advancements in this sector [2]. Group 1: Forum Overview - The NFUCon 2025 will be held from November 27-29, 2025, in Hangzhou, Zhejiang, organized by DT New Materials and the National Key Laboratory of Bio-based Transportation Fuels [2][3]. - The forum will gather industry representatives and experts to explore key areas such as green pretreatment of biomass, non-grain sugars, bio-based chemicals and materials, and biomass energy [2][4]. Group 2: Forum Agenda - The forum will feature two main thematic forums: - The first focuses on non-grain bio-based chemicals and materials, including sessions on biomass green pretreatment and non-grain sugars [6][9]. - The second focuses on non-grain biomass energy, covering topics like biomass methanol, fuel ethanol, biogas, and sustainable aviation fuel (SAF) [9][10]. Group 3: Supporting Institutions - The forum is supported by various institutions, including Zhejiang University and its relevant departments, as well as editorial boards of related journals [4][5]. - The organizing committee includes prominent figures from Zhejiang University, enhancing the forum's academic and industry credibility [3]. Group 4: Special Activities - A special activity titled "Technology Achievement Display and Docking" will be held to promote the commercialization of innovative results in the biomass utilization field, showcasing 50 selected projects [9][10]. Group 5: Industry Participation - The forum will attract a diverse range of participants, including biomass energy and chemical developers, academic researchers, and solution providers in biomass processing technologies [14]. - It aims to facilitate collaboration among industry, academia, and government organizations to advance the biomass sector [14].

Core Viewpoint - The article discusses advancements in enzymatic hydrolysis and biosynthesis of value-added products from PET waste, highlighting the importance of biological recycling methods in addressing global plastic pollution and enhancing the economic viability of PET recycling [2][4][27]. Group 1: PET Waste and Environmental Impact - The global production of PET reached 88.1 million tons in 2022, with significant waste accumulation due to its non-biodegradable nature and inefficient recycling methods [3]. - Traditional mechanical and chemical recycling methods face limitations, while biological recycling offers a more environmentally friendly and energy-efficient alternative [4][16]. Group 2: Enzymatic Hydrolysis Mechanism - PET is hydrolyzed into its monomers, ethylene glycol (EG) and terephthalic acid (TPA), through the action of specific enzymes, primarily carboxylesterases [5][7]. - The hydrolysis process involves two main steps: acylation and deacylation, facilitated by the enzyme Is PETase, which has gained attention for its efficiency at ambient temperatures [5][7]. Group 3: Enhancing Enzymatic Efficiency - Strategies to improve PET hydrolysis efficiency include enzyme engineering, substrate pretreatment, and optimization of reaction conditions [8][14]. - Enhancing the thermal stability of PET hydrolases allows for more effective catalysis near PET's glass transition temperature, which is crucial for improving substrate accessibility [9][11]. Group 4: High-Value Conversion of PET Products - The hydrolysis products TPA and EG can be converted into high-value chemicals through metabolic engineering, significantly increasing the economic feasibility of PET recycling [17][20]. - Various microorganisms can metabolize TPA into valuable products such as polyhydroxyalkanoates (PHA) and vanillin, while EG can be assimilated into central metabolic pathways for the production of various chemicals [18][20]. Group 5: Economic and Process Considerations - The economic viability of enzymatic PET recycling is influenced by factors such as degradation efficiency, substrate load, and enzyme costs, which directly affect product yield and purity [16][28]. - A comprehensive optimization approach that includes both enzyme performance and process system improvements is essential for achieving sustainable and efficient PET recycling [16][27].

Core Viewpoint - The article emphasizes the development of non-grain biomass resources for energy and bio-based materials, highlighting the upcoming NFUCon 2025 forum aimed at discussing commercialization paths and technological advancements in this sector [2]. Group 1: Forum Overview - The NFUCon 2025 will be held from November 27-29, 2025, in Hangzhou, Zhejiang, organized by DT New Materials and the National Key Laboratory of Bio-based Transportation Fuels [2][3]. - The forum will gather industry representatives and experts to explore key areas such as green pretreatment of biomass, non-grain sugars, bio-based chemicals and materials, and biomass energy [2][4]. Group 2: Forum Agenda - The forum will feature two main thematic forums: - The first focuses on non-grain bio-based chemicals and materials, including sessions on biomass green pretreatment, non-grain sugars, and bio-based chemicals [6][9]. - The second thematic forum will address non-grain biomass energy, covering topics like biomass methanol, fuel ethanol, biogas, and sustainable aviation fuel (SAF) [9][10]. Group 3: Supporting Units and Participants - The forum is supported by various institutions, including Zhejiang University and its relevant departments, as well as editorial boards of related journals [4]. - Participants will include production enterprises in biomass energy and chemicals, academic experts, and solution providers in biomass processing technologies [14]. Group 4: Special Activities - A special activity for technology achievement display and matchmaking will be held, aiming to promote innovation and commercialization in the biomass sector [9]. - The forum will showcase 50 innovative projects with commercial potential in biomass utilization [9]. Group 5: Laboratory Background - The National Key Laboratory of Bio-based Transportation Fuels was established through a collaboration between Tian Guan Enterprise Group, Zhejiang University, and Zhengzhou University, focusing on energy security and carbon neutrality strategies [17].

Core Viewpoint - The article discusses the advancements in synthetic biology and the key technologies selected by Anhui Province for the 2025 manufacturing "recruitment and innovation" initiative, highlighting the focus on bio-manufacturing and its applications in various industries [2][3]. Summary by Sections Global Policy Progress - Anhui Province's Industrial and Information Technology Department announced a public list of 325 key technology tasks and 3 innovation tasks for small, medium, and large enterprises as part of the 2025 manufacturing initiative [2]. Key Technologies Involved - The selected tasks include several related to synthetic biology, such as: - New anaerobic fermentation processes for mixed raw materials with a biogas yield of over 1.1 m³/m³·d and methane concentration above 65% [4]. - Biogas purification technology with a recovery rate of ≥99% [4]. - Development of biogas liquefaction equipment meeting national quality standards [4]. - High-value conversion of agricultural waste into biogas with specific quality parameters [4]. - Research on antibody molecules with specific antigen binding capabilities [4]. - AI-assisted enzyme directed evolution for the synthesis of specific compounds [4]. Industrial Applications - The article outlines various applications of synthetic biology technologies, including: - Production of amino acids with specific fermentation yields and glucose conversion rates [5]. - Development of microbial agents with high fermentation efficiency and specific bacterial counts [5]. - Establishment of standards and patents for new biomanufacturing processes [5]. Conclusion - The focus on synthetic biology in Anhui's manufacturing strategy indicates a significant push towards innovation in bio-manufacturing, aiming to enhance productivity and sustainability across multiple sectors [2][3].

Core Viewpoint - The article emphasizes the development of non-grain biomass resources for energy and bio-based materials, highlighting the upcoming NFUCon 2025 forum aimed at discussing commercialization paths and technological advancements in this sector [2][3]. Group 1: Forum Overview - The NFUCon 2025 forum will take place from November 27 to 29, 2025, in Hangzhou, Zhejiang, organized by DT New Materials and the National Key Laboratory of Bio-based Transportation Fuels [2][3]. - The forum will gather industry representatives and experts to explore key areas such as green pretreatment of biomass, non-grain sugars, bio-based chemicals and materials, and biomass energy [2][3]. Group 2: Supporting Institutions - The forum is supported by various institutions including Zhejiang University and its departments focused on polymer science, bio-systems engineering, and food science [4]. - The organizing committee includes prominent figures from Zhejiang University, such as Li Zhenglong and Zhang Xinghong, who are experts in bio-based fuels and chemicals [3]. Group 3: Forum Agenda - The agenda includes specialized sessions on topics like biomass green pretreatment, non-grain sugars, bio-based chemicals, and materials, as well as biomass energy sources like methanol and sustainable aviation fuel (SAF) [5][6][9]. - A special feature of the forum will be the "Technology Achievement Display and Matching" event, which aims to promote innovation and commercialization in the biomass sector [9][10]. Group 4: Industry Participation - The forum will attract a diverse range of participants, including biomass energy and chemical developers, academic researchers, and solution providers for biomass processing technologies [14]. - Key areas of focus will include the development of cellulose-based materials, non-grain industrial sugars, and high-value chemical transformations from biomass [10][14].

Group 1 - The core viewpoint of the article highlights the establishment of a joint venture between Yihai Kerry (Golden Dragon Fish) and Xinhua Yang to enter the synthetic biology industry, focusing on the production of various enzymes and bio-based materials [2][4]. - Yihai Kerry is a significant player in the agricultural and food processing sector in China, involved in multiple industries including edible oil refining, food ingredients, and deep processing of grains [2][4]. - Xinhua Yang is recognized as one of the top ten enzyme preparation manufacturers in China, specializing in microbial ecological preparations [3]. Group 2 - The joint venture, named Xinhua Yang Yihai Kerry, aims to utilize synthetic biology technology to produce food-grade enzymes, feed enzymes, and other industrial enzymes, targeting global markets [4]. - By December 2024, Yihai Kerry plans to establish two companies with Fuxiang Pharmaceutical, focusing on the manufacturing and sales of food ingredients and pharmaceutical intermediates, with an expected annual production capacity of 200,000 tons [6]. - Fuxiang Pharmaceutical is noted for being the first company in China to achieve industrialization of filamentous fungal protein at a scale of over 1,000 tons, and is accelerating the construction of a project with an annual capacity of 20,000 tons of microbial protein and 50,000 tons of amino acid water-soluble fertilizer [7].

Core Viewpoint - The article emphasizes the importance of talent acquisition in the field of synthetic biology and protein engineering, highlighting the need for skilled professionals to drive innovation and application in the industrial biotechnology sector [4][5]. Talent Demand - The Tianjin Institute of Industrial Biotechnology is inviting talented individuals from both domestic and international backgrounds to join its efforts in advancing the industrial biotechnology industry [4]. - The Multi-Peptide and Protein Engineering Research Center focuses on synthetic biology innovations, aiming to address challenges in resources, environment, health, and bio-manufacturing [4]. Research Center Overview - The center integrates various disciplines such as microbiology, molecular biology, biochemistry, structural biology, protein engineering, bioinformatics, and computational biology to enhance synthetic biology strategies [4]. Researcher Profile - Zhang Yanfei, a researcher and doctoral supervisor, leads the Multi-Peptide and Protein Engineering Research Center, with a strong academic background and extensive research experience in synthetic biology and metabolic engineering [5]. Job Opportunities - Positions available include Assistant Researcher and Special Research Assistant (Postdoctoral), with competitive salaries and additional funding opportunities from local government initiatives [8][10]. - The Tianjin Port Free Trade Zone offers a funding support of 300,000 yuan for outstanding postdoctoral researchers, which can be combined with the institute's salary [8]. Additional Benefits - Postdoctoral researchers who achieve significant results can apply for higher-level positions within the institute and receive competitive compensation and development opportunities [10][15]. - The institute provides various benefits, including social insurance, housing fund contributions, health check-ups, and paid annual leave [13][14]. Application Process - Applicants are required to submit their resumes and complete the application form, with a long-term open application period [12][18].

非粮生物质论坛 | 2025论坛官宣 近年，国家已发布一系列关于非粮生物基材料创新发展的方案，致力于打造基于大宗农作物秸秆、竹 子等非粮生物质资源利用的生物质能源和生物基材料体系。 非粮生物质利用产业未来 3-5年的发展 趋势？可商业化的路径？有哪些值得关注的技术团队和企业？从产业链角度和技术角度的挑战和解决 方案？ 一系列问题待剖析，一系列的产业机会也正被挖掘。 DT新材料旗下 【 生物基能源与材料】长期致力于生物基和生物制造产业的科技服务平台，拥有 5 万多 产业上下游数据， 是行业最重要的资源和信息枢纽之一 。 DT新材料 将 联合 生物基运输燃料技术全国重点实验室 将于 202 5 年 1 1 月 27-29 日 在 浙江 ·杭州 举办 " 202 5 （第 五 届）非粮生物质高值化利用论坛 （ NFUCon 2025 ） "，将邀约业 界上下游代表性企业与专家，探讨生物质绿色预处理、非粮糖、生物质基化学品和材料、生物质能 （甲醇、燃料乙醇、生物沼气、可持续航空燃料（ SAF））等重要方向，共同推动非粮生物质大规 模应用，助力实现双碳目标。 01 组织机构 / NFUCon 2025 主办单位 ： 宁 ...