Core Insights - The article highlights the recent progress of Heilongjiang Xinhecheng in launching multiple fermentation projects, indicating a strategic expansion in biobased energy and materials production [2][3][4]. Group 1: Project Developments - Heilongjiang Xinhecheng is undertaking two major fermentation projects, including the A9, A10, and functional fermentation products project, which aims to establish a production capacity of 5,000 tons/year for A10, 6,000 tons/year for A9, and smaller capacities for other products [3]. - The A18, A20, and isocyanic acid project will utilize existing facilities to produce 1,000 tons/year of A18, 10,000 tons/year of isocyanic acid, and 3,000 tons/year of A20, with an estimated investment of 83.16 million yuan [4]. Group 2: Financial Performance - Heilongjiang Xinhecheng reported impressive financial results, with revenues reaching 21.6 billion yuan and a net profit of 5.869 billion yuan, showcasing significant growth in its operations [5]. Group 3: Industry Events - The SynBioCon 2025 conference will be held from August 20-22 in Ningbo, focusing on synthetic biology and green manufacturing, highlighting the industry's trends and opportunities [9][10][11].

菌株是生物质炼制的 "芯片"，是以生物质为原材料的新型生物制造产业链和绿色低碳生物经济的核心。 用于生物制造的菌株细胞通常面临中间代谢产物积累、毒性产物抑制，导致反应效率低、终产物浓度低的问题，严重制约了绿色生物制造的发展。因 此，" 如何构建菌株细胞并强化反应过程合成生物基产品 "是该领域重要的研究课题。 以" 菌株细胞工厂构建及产物合成强化 "为核心，以" 人工细胞器创制、菌株细胞工厂构建、反应分离耦合调控 "从微观到宏观强化产物生物合成，可 以强化生物制造过程。 多 年来， 大连理工大学薛闯教授 团队创建了多酶自组装蛋白质笼的人工细胞器，该人工细胞器可实现化学诱导、光诱导提升细胞器的可调节性，揭 示了人工细胞器的时空调控机制；创建了"多枪-多靶"快速菌株构建方法，揭示了磷酸化激酶多维度协同调控菌株的新机制，阐明了梭状芽孢杆菌群体 感应系统中信号分子自诱导肽的合成途径和调控功能；制备了碳纳米管阵列复合膜，开发了反应分离耦合技术。实现了 以生物能源为主的产品生物合 成强化 ， 为解决工业生物技术领域催化效率低的瓶颈问题提供了新突破点与新思路 。 点击更多阅读 ： 祝贺！80后生物制造专家-薛闯教授获大奖，全 ...

Core Viewpoint - DSM-Firmenich, a major player in the chemical industry, has shown significant financial growth in the first half of 2025, with total sales reaching €6.51 billion (approximately ¥53.64 billion), a year-on-year increase of 3% [2]. Group 1: Financial Performance - The adjusted EBITDA for DSM-Firmenich was €1.26 billion, reflecting a 29% increase year-on-year, with the EBITDA margin rising from 15.5% to 19.4% [2]. - The net profit surged from €50 million in the same period last year to €541 million, marking an almost tenfold increase [2]. Group 2: Business Segments - The Animal Nutrition and Health segment reported sales of €1.751 billion, a 14% increase year-on-year, with adjusted EBITDA soaring by 293% due to improved core business and temporary vitamin price effects [3]. - The Fragrance and Beauty segment saw sales of €1.989 billion, a slight decline of 1%, impacted by weak demand for sun care products and customer inventory destocking [3]. - The Taste, Texture, and Health (TTH) segment achieved sales of €1.686 billion, a 3% increase year-on-year [3]. - The Health, Nutrition, and Care (HNC) segment reported sales of €1.072 billion, down 2%, but organic sales grew by 6% [3]. Group 3: Strategic Developments - DSM has undergone significant transformations since its founding in 1902, evolving from a coal mining company to a leader in specialty chemicals and nutrition [4][5]. - The merger with Firmenich in May 2023 has positioned DSM-Firmenich as a global leader in flavor and fragrance manufacturing and the largest vitamin producer [5]. - The company has strategically divested from capital-intensive sectors to focus on high-margin specialty chemicals and nutrition, aligning with market trends [5]. Group 4: Competitor Landscape - Competitors like Wanhua Chemical and New Hope Liuhe are also expanding their nutrition and flavor businesses, indicating a competitive landscape in the sector [6][7]. - New Hope Liuhe reported a record revenue of ¥21.609 billion in 2024, with a 42.95% year-on-year growth, highlighting the robust performance of its nutrition segment [6].

未来食品&农业 | 微元合成 【SynBioCon】 获 悉 ，近日，合成生物学领域的新锐力量—— 芝诺科技 ，成功完成了 数千万元 人民币的Pre-A轮融资 ，在此之前，芝诺科技已经完成了来自中信创投和嘉程资本等知名投资方的 历史 投资。 此次融资将为 芝诺科技 注入强大动力，助力公司在 生产能力提升、管线拓展、团队扩 张以及商业化落地等方面实现跨越性发展。 专题论坛3 来来最品&农业GEN 芝诺科技成立于2020年，是一家专注于合成生物学技术的国家高新技术企业，总部位于北京， 在苏 州、山东东营设有研发中心与百吨级生产基地 。公司核心团队汇聚了来自牛津大学、北京大学等顶 尖机构的跨学科人才，创始人朱天择博士深耕糖化学与代谢流优化十余年，其领衔的技术团队通过 CRISPR 等新一代基因编辑技术，实现工程菌产率较野生型提升千倍以上，生产效率较传统方法提 高十倍。 其关键技术亮点： ▌ 参考信息： 本文部分素材来自公开信息。由作者重新编写，系作者个人观点，本平台发布仅为了传达一种不同观点，不代表 对该观点赞同或支持。如果有任何问题，请联系我们：15356747796（微信同号）。 代谢流精准设计：构建覆盖模式菌 ...

Core Insights - The fourth Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI with bio-manufacturing, green chemicals, new materials, future food, and agriculture [2][30] - The conference aims to explore the development trends of the bio-manufacturing industry during the 14th Five-Year Plan, innovations driven by AI, and the technologies and products that will sustain the vitality of the bio-manufacturing sector [2][30] Organizational Structure - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and supported by various academic and industry institutions, including Peking University Ningbo Institute of Ocean Medicine and the Zhejiang Synthetic Biology Industry Technology Alliance [3][4] Conference Agenda - The agenda includes a series of forums and discussions, such as the Bio-Manufacturing Industry Leaders Forum and the closed-door seminar for the "2025 AI Empowering Bio-Manufacturing Industry Innovation Development Blue Book" [7][19] - Key topics will cover AI applications in bio-manufacturing, green chemistry, and new materials, with specific sessions dedicated to future food and agriculture innovations [9][25] Notable Participants - The conference will feature industry leaders and experts from various organizations, including universities and biotech companies, who will present their research and innovations in synthetic biology and bio-manufacturing [10][11][12] Special Activities - Concurrent activities will include a youth forum on bio-manufacturing, technology showcases, and networking opportunities for industry professionals [2][19]

Core Insights - The fourth Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI with bio-manufacturing, green chemicals, new materials, future food, and agriculture [2][3]. Group 1: Conference Overview - The conference aims to explore the development trends of the bio-manufacturing industry during the 14th Five-Year Plan, innovations driven by AI, and the technologies and products that will sustain the vitality of the bio-manufacturing sector [2]. - Various activities will be held concurrently, including a Youth Forum on Bio-Manufacturing, a high-level roundtable discussion, and a closed-door seminar on the "2025 Blue Book for AI Empowering Bio-Manufacturing Innovation" [2][3]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and supported by several academic and industry institutions, including Peking University Ningbo Institute of Ocean Medicine and the Zhejiang Synthetic Biology Industry Technology Alliance [3][4]. Group 3: Agenda Highlights - The agenda includes a macro forum on the bio-manufacturing industry, thematic forums on green chemicals and new materials, and AI empowerment in bio-manufacturing [7][9]. - Specific sessions will cover topics such as the application of enzyme molecular engineering, the design of cell factories, and the production of bio-based materials [11][19]. Group 4: Industry Participation - Numerous industry leaders and representatives from over 20 companies will participate in the high-level roundtable discussion, including notable firms like Ningbo Enzyme Science Bioengineering Co., Ltd. and Beijing University Ningbo Institute of Ocean Medicine [10]. - The conference will also feature a showcase of synthetic biology innovations and technology transfer opportunities [2][23]. Group 5: Future Developments - The conference will announce the "China Synthetic Biology Industry Distribution Map (2025 Edition)" and the list of 500+ representative enterprises in the bio-manufacturing sector [34][35].

Core Viewpoint - Lifebio has recently completed a multi-billion B2 round financing led by the listed company Xin Fengming, with participation from GGV Capital and several existing shareholders [2][3]. Group 1: Company Overview - Lifebio is a leading global company in bio-based aromatic materials, having developed a unique "biomass-glucose-HMF-FDCA" process over more than a decade, which allows for the production of furan-based bio-materials without relying on food-sourced fructose [3][10]. - The company has established the world's first FDCA production line with a capacity of 1,000 tons and has initiated the construction of a 10,000-ton production line in Tongling, Anhui, in September 2024 [10][11]. Group 2: Investment and Partnerships - Xin Fengming, the lead investor in the recent financing round, is a major player in the polyester industry, with over 15% of global polyester filament capacity [4][7]. - GGV Capital, another significant investor, is a top-tier venture capital firm with over $9 billion in assets under management and a history of investing in over 500 companies, including Alibaba and Airbnb [7][8]. - Lifebio's previous investors include Lan Chuang Capital, which is associated with the listed company Zhongkong Technology, and Chengkai Fund, linked to Wankai New Materials, which has completed trial production of bio-based furan polyester [7][8]. Group 3: Industry Development - Lifebio has achieved the industry's first large-scale production of 100% bio-based polyester PEF filament through collaboration with leading companies [6][16]. - The company is focusing on non-food biomass sources such as corn cobs and straw to produce bio-based PEF, which can be applied in packaging materials, textiles, and electronics [13][19]. - Lifebio has signed a strategic cooperation agreement with Moutai to accelerate the application of bio-based materials in bottle caps and containers [19][20].

Core Viewpoint - The collaboration between Micro Yuan Synthetic and Cargill aims to promote the application of Allulose in the Chinese market, focusing on healthier, lower-calorie, and flavorful product innovations [2][3]. Group 1: Partnership and Market Expansion - Micro Yuan Synthetic has signed a partnership agreement with Cargill, the largest food and ingredient company globally, to distribute Allulose in China [2]. - Cargill will leverage its extensive B2B platform and diverse customer network to expand the application scenarios of Allulose in the Chinese market [7]. Group 2: Product Innovation and Approval - Allulose has been approved by relevant national authorities as a new food ingredient in China, marking a significant step for its market introduction [3]. - As a natural, low-calorie rare sugar, Allulose offers a taste experience similar to sucrose while demonstrating advantages in blood sugar response and energy intake control [3]. Group 3: Production Capabilities - Micro Yuan Synthetic is the only company globally that produces Allulose using fermentation technology and has obtained the first administrative license for its production in China [4]. - The company has established an efficient production chain from biological fermentation to purification, resulting in high purity, good sensory properties, and wide applicability across various food categories such as functional beverages, dairy, candies, and baked goods [6]. Group 4: Industry Events - The 2025 Synthetic Biology and Green Bio-Manufacturing Conference will be held from August 20-22 in Ningbo, Zhejiang, focusing on the industrialization progress and opportunities in synthetic biology and green manufacturing [13]. - The conference will include various activities such as a youth forum, high-level discussions, and a showcase of synthetic biology technology achievements [13].

Core Viewpoint - The article emphasizes that biomanufacturing is becoming a key engine for the transformation and upgrading of the chemical industry, driven by the global green transition and "dual carbon" goals [2]. Group 1: Biomanufacturing and Chemical Industry Transformation - Biobased materials, derived from renewable biomass such as starch, cellulose, and fats, are fundamentally changing the linear economic model of "mass production, mass consumption, and mass waste" through a circular economy approach [2]. - Synthetic biology and biomanufacturing utilize biomass as raw materials, leveraging the metabolic functions of microorganisms, cells, and enzymes to achieve large-scale production of target products [3]. - Key pathways for the green transformation of the chemical industry include the development of non-food biobased synthetic products, green biomanufacturing of plastic monomers like dicarboxylic acids and diols, utilization and conversion of one-carbon resources like CO2, and enzymatic recycling of waste plastics [3]. Group 2: Upcoming Conference and Expert Participation - The Fourth Synthetic Biology and Green Biomanufacturing Conference will be held from August 20-22 in Ningbo, Zhejiang, featuring a session on green chemicals and new materials with participation from prominent experts and representatives from biomanufacturing companies [4]. - Notable speakers include Professor Wang Dan from Chongqing University, Professor Xue Chuang from Dalian University of Technology, and Yang Shihui, founder of Wuhan Ruijia Kang, who will discuss various aspects of biomanufacturing and its applications [6][7]. Group 3: Conference Agenda Highlights - The conference will include discussions on cell factory design, microbial cell factories for plastic monomers, and green separation and purification technologies in synthetic biology [30][35]. - A special focus will be on the application of non-food biomass sugars in synthetic biology and green biomanufacturing, showcasing flexible production platforms [7]. - The agenda also features a series of forums on AI empowerment in biomanufacturing and future food and agriculture innovations [14][43]. Group 4: Industry Collaboration and Research - The conference is organized by DT New Materials in collaboration with various academic and research institutions, highlighting the importance of industry-academia partnerships in advancing biomanufacturing technologies [10][16]. - The event aims to promote the sharing of innovative research and practical applications in the field of biomanufacturing, contributing to the overall growth of the industry [39].

蓝晶微生物 建立了自动化数字化的黑灯实验室研发平台，利用合成生物技术不断迭代增效剂生物制造的菌株和工艺，开发了一系列 新型植物刺激素 的工业化合成技术，以解决农业生产中未被满足的需求。 如2024年11月，蓝晶微生物首个面向农业市场的 多生菌脂（PHA）产品矩阵 。 这款产品主要针对农业，是一种能 有效激活根际微生物的天然物质 。 来源：蓝晶微生物 其产品矩阵包括 蓝多丰™ 微生物菌剂、多生元™ 有机水溶肥料、根际蓝™ 含氨基酸水溶肥料等 。这些产品从增产提质的实际功效出发，围绕不同 场景、不同作物的差异化需求，为农业用户和合作伙伴提供全方位、精准化支持，共同推动农业绿色健康发展迈向新高度。 点击更多阅读 ： 蓝晶微生物，正式进军农业赛道！ SynBioCon 大会 | 蓝晶微生物 农业是我国的基础产业，提升农业单产需要底层技术创新带来的新质生产力，合成生物技术可以提供生长刺激、生物防控、生物肥料等绿色农业增效 剂。 对此， 蓝晶微生物首席科学家 饶驰通 将出席 8 月20-22日 在 浙江·宁波 举办的 SynBioCon 2025 第四届合成生物绿色生物制造大会 「未来 食品&农业 」专 场 分 享以 《 ...