/生物制造产业社群/ 让上下游聚在一起, 未来食农、绿色化工、大健康、美妆个护 等产业同行❤️↓ 资本事件 | 康维健生物 【SynBioCon】 获 悉，近日， 康维健生物医药有限公司 （后简称" 康维健 "） 完成B轮融资 ， 本轮投资资方包括 普 华资本、德联资本、鼎晖投资、东方嘉富 以 及 贵州茅台 。 本轮融资将为康维健扩大生产能力和优化研发提供资金支持，同时也有助于加快产品商业化进程，满 足市场对 高品质生物医药产品 日益增强的需求。 抗坏血酸棕榈酸酯应用覆盖食品、保健品、化妆品及医药等领域 本轮融资完成后，康维健将进一步加强技术研发、拓展市场布局，巩固其在生物技术与健康产品供应 领域的竞争力。 点击更多阅读： 茅台发声，事关生物经济赛道3-5年布局！ 茅台：再成立合成生物基金！ 茅台，生物可降解新材料新动作！ ▌ 参考信息：本文部分素材来自公开信息 。由 作 者 重新 编写，系作者个人观点，本平台发布仅为了传达一种不同 观点，不代表对该观 点或支持。如果有任何问题，请联系我们：15381397601（微信同号）。 康维健成立于2019年，是一家生物合成技术平台公司，致力于为全球食品、化妆品原料、 ...

/DT非粮生物质利用交流群/ 让专业的人聚在一起, 非粮生物质利用/三素分离/生物质能源/生物炼制等产业同行❤️↓ 非粮生物质利用 | 非粮糖 【SynBioCon】 获 悉， 近日， 山东大学微生物改造技术全国重点实验室 钟耀华教授课题组 在纤维 素酶 生产及 木质纤维素糖制备方面取得重要进展。 挖掘出具有超高β-葡萄糖苷酶活性的里氏木霉工程菌株SCB18 ， 成功建立了底物负荷为35%的玉米 秸秆高固糖 化体系 ，获得了 144.5 g/L的木质纤维素糖 ，同时成功将 纤维素酶 用量降低到了 3 FP U/g DM 。 相关研究成果以"Achieving high-concentration lignocellulosic sugars by using theTrichod erma reesei strain with high β-glucosidase activity for inducersynthesis and cellulase pr oduction"为题发表于工程技术领域国际知名期刊《Chemical Engineering Journal》（ IF 13.2 ）。 木质纤维素生物质 ...

尽管 苯乙酮及其衍生物的生物学功能已被充分报道 ， 但其 生物合成途径 仍 有待阐明 。 虽 有研究指出 苯乙酮可能通过 β-氧化途径 生成 ， 也有研究 通过同位素标记证实 苯丙氨酸代谢产生的 肉桂酸 是苯乙酮 的合成 前体 ， 然而该 合成途径中 的 具体酶 促反应步骤 和涉及的酶尚不明确 。 【SynBioCon】 获 悉， 2025年 9 月 5 日， 西北农林科技大学 徐凌飞 教授带领的梨研究团队 在 Nature Plants 在 线 发 表 了 题 为 " Naturally impaired side-chain shortening of aromatic 3- ketoacyl-CoAs reveals the biosynthetic pathway of plant acetophenones "的研究论文 （ 梨领域 首篇 ） 。该研究 以梨为材料，揭示了苯乙酮类化合物的 完整 生物合成途 SynBio团队 | 西北农林科大徐凌飞教授、苯乙酮 苯乙酮及其衍生物 在 植物 界 和微生物 界中分布 广泛 ， 具有多样的生物学功能。 在植物界， 苯乙酮 （acet ophenone ） 是 ...

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从产业生态搭建来看， 微康益生菌拥有亚洲最大的益生菌菌种研发智能制造基地 ，产品更是获评拜耳制药全球最佳供应商；还成功孵化 益一科技、康科 生物、修喵修勾科技、玖明医疗等企业 ，覆盖医疗健康、膳食营养、宠物健康等细分领域，有效补全鼓楼合成生物产业链条。 SynBio团队 | 黄和院士 【SynBioCon】 获 悉， 近 日，鼓楼区政府与南京师范大学共建的 智能生物制造创新中心 启动仪 式在南京幕府智谷成功举办。 中心以合成生物学底层技术为核心，打造"1+1+N"创新模式，既依托南师大科研平台攻克核心技术，又联动企业推动成果落地，真正破解 "实验室突破 难转化为产业产品"的痛点 。 值得关注的是， 中国工程院院士、 南京师 范大学副校长黄和将担任智能生物制造创新中心管委会主任 。他将带领团队聚焦生物制造前沿领域，依托新 科学与新技术，推动创新中心打造成为合成生物学科研高地，为生命健康产业集群发展提供有力支撑。 仪式现场，黄和院士还为 微康益生菌 、纽邦生物、迪必尔生物工程、北极光等 企业负责人颁发智能生物制造创新中心产业顾问聘书。 此次活动签约的海尔生物、德悦普惠医疗、量准科技等项目，进一步覆盖 细胞库建设 ...

Core Viewpoint - The article emphasizes the development of non-grain biomass resources for energy and bio-based materials, highlighting the upcoming NFUCon 2025 forum aimed at discussing commercialization paths and technological advancements in this sector [2]. Group 1: Forum Overview - The NFUCon 2025 forum will take place from November 27 to 29, 2025, in Hangzhou, Zhejiang, organized by DT New Materials and the National Key Laboratory of Bio-based Transportation Fuels [2][3]. - The forum will gather industry representatives and experts to explore key areas such as green pretreatment of biomass, non-grain sugars, bio-based chemicals and materials, and biomass energy [2][4]. Group 2: Forum Agenda - The forum will feature a series of specialized sessions, including topics on biomass green pretreatment technologies, non-grain sugars, bio-based chemicals, and non-grain biomass materials [6][9]. - A special focus will be on sustainable aviation fuel (SAF) and the conversion of agricultural residues into valuable energy sources [10]. Group 3: Supporting Institutions - The forum is supported by various academic and research institutions, including Zhejiang University and its associated laboratories, which focus on polymer science, bio-systems engineering, and biomass utilization [4][14]. - The event will also involve participation from enterprises engaged in biomass energy and chemical development, as well as government and association organizations [14]. Group 4: Special Activities - A special activity will be held for showcasing and connecting innovative projects in the biomass utilization field, with a goal of promoting commercialization and industry collaboration [9][10].

Core Viewpoint - The article emphasizes the importance of industrial biotechnology in supporting China's sustainable development and innovation in the bio-economy, focusing on key technologies and research areas that can replace fossil resources with renewable carbon resources and enhance industrial processes through modern biotechnology [5][20]. Group 1: Research Focus - The research institute focuses on three strategic themes: replacing fossil resources with renewable carbon resources, using clean biological processing instead of traditional chemical methods, and enhancing industrial levels through modern biotechnology [5]. - Key research areas include industrial protein science and biocatalysis engineering, synthetic biology and microbial manufacturing engineering, and biological systems and bioprocess engineering [5]. Group 2: Team Introduction - Zhang Yiheng, a prominent researcher and doctoral supervisor, leads the Low Carbon Synthesis Engineering Biology National Key Laboratory and has made significant contributions to the field, including the establishment of the in vitro BioTransformation (ivBT) engineering technology system [6]. - Zhang Yuzhen, another researcher, has developed microfluidic technologies for quantitative studies of microbial populations and is working on high-throughput identification techniques for important industrial enzymes [7][8]. Group 3: Recruitment Information - The institute is seeking to hire 2-3 postdoctoral research assistants and 1-2 assistant researchers, with a focus on candidates holding doctoral degrees in microbiology, molecular biology, or enzyme engineering [9][10]. - Competitive salaries and benefits are offered, including social insurance, housing funds, and opportunities for professional development and overseas visits [11][12]. Group 4: Career Development - Postdoctoral researchers can apply for permanent positions with competitive salaries and development opportunities, including potential advancement to senior technical roles based on their research achievements [13][14]. Group 5: Upcoming Events - The article mentions an upcoming forum on non-grain biomass high-value utilization, scheduled for January 27-29, 2025, in Hangzhou, focusing on clean pretreatment of biomass and commercialization of bio-based materials and fuels [20].

Core Insights - The article highlights the recent launch of a thousand-ton synthetic biology flexible production line by Siping Technology in Rugao, Jiangsu, marking a significant step in the company's full-chain layout in synthetic biology [2] - Siping Technology aims to become an innovative leader in synthetic biological manufacturing platforms, focusing on high-performance bio-based materials and carbon-negative intelligent manufacturing [2] - The company has partnered with the Tianjin Institute of Industrial Biotechnology to develop bulk bio-based material monomer products using methanol, aiming to reduce reliance on food carbon sources and promote "one-carbon bio-manufacturing" [4] Group 1 - Siping Technology's new production line is a key component in scaling up biological manufacturing technology and aims to lead the industry towards intelligent, non-food, and sustainable development [2] - The product matrix includes carbon-negative new materials, polymer monomers, and high-value-added compounds, with a focus on efficient conversion from laboratory technology to industrial application [2] - The collaboration with the Tianjin Institute is based on shared strategic goals, leveraging the institute's expertise in low-carbon synthetic biology and Siping's advancements in bio-based products [4] Group 2 - The national strategy emphasizes the innovation and development of non-food bio-based materials, utilizing resources like crop straw and bamboo [7] - A forum on high-value utilization of non-food biomass is scheduled for November 2025 in Hangzhou, focusing on clean pretreatment, non-food sugars, chemicals, and biofuels [7]

Core Viewpoint - The article discusses the recent legislative measures taken by Shenzhen to promote the synthetic biology industry, which is considered a new "golden track" in the context of the third biotechnology revolution. The new regulations aim to support innovation and development in this emerging sector, establishing a comprehensive service support system for synthetic biology enterprises [2][3]. Summary by Sections Legislative Framework - Shenzhen has passed the "Regulations on Promoting the Innovative Development of the Synthetic Biology Industry," which will take effect on October 1. This legislation is a pioneering effort in the field of industrial promotion and aims to address development bottlenecks in the synthetic biology sector [2][3]. Industry Support and Ecosystem - The regulations outline a full-chain service support system for synthetic biology, emphasizing the importance of source innovation for technology transfer. Approximately 40% of new synthetic biology enterprises in China have been established in Shenzhen over the past three years [4]. Product Market Entry - The regulations include measures to shorten the product market entry cycle for synthetic biology products, addressing the challenges of lengthy approval processes. This includes exploring new models for evaluation and technical institutions, as well as promoting the market demand for synthetic biology products through curated lists and procurement facilitation [6][7]. Financial and Spatial Support - The regulations reinforce the need for spatial and financial support for the synthetic biology industry. They prioritize land supply for enterprises and encourage financial institutions to lower financing costs for startups in this sector. Additionally, there are efforts to streamline approval processes and enhance the regulatory environment for synthetic biology enterprises [7].

Core Viewpoint - The article highlights the launch of the Zhejiang Zhenyuan Biological Industrialization Base, emphasizing its significance in the synthetic biology sector and its role in promoting high-quality economic development in Shaoxing [3][5]. Company Progress - Zhejiang Zhenyuan officially inaugurated its biological industrialization base on August 30, marking a key milestone in the development of synthetic biology and the production of high-end amino acids [3][5]. - The base is the first in China to feature a thousand-ton-level industrialization facility for the biosynthesis of histidine, showcasing advanced synthetic biology and fermentation engineering technologies [5][6]. - The project has received recognition as a major industrial project in Zhejiang and is part of the national green low-carbon advanced technology demonstration projects [5][6]. Financial Performance - In the first half of 2025, Zhejiang Zhenyuan reported a revenue of 1.283 billion yuan, a decrease of 34.49% year-on-year, while net profit attributable to shareholders increased by 29.27% to 56.26 million yuan [6][7]. - The company’s net profit, excluding non-recurring gains and losses, was 30.12 million yuan, down 20.32% compared to the previous year [6][7]. - The company’s total assets decreased by 13.55% to approximately 2.955 billion yuan, while net assets attributable to shareholders increased by 2.62% [7]. Industry Context - The synthetic biology sector is recognized as a core component of the "third biological technology revolution," with significant support from local government policies and funding exceeding 10 billion yuan [5][6]. - The base aims to replace traditional high-pollution and high-energy consumption processes with green technologies, contributing to the development of a sustainable industrial ecosystem [6][8]. - The project aligns with national strategies for the innovation and development of non-grain biomass materials, focusing on clean energy and material systems [10].