香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性 或完整性亦不發表任何聲明，並明確表示概不就因本公告全部或任何部分內容而產生或因倚賴 該等內容而引致的任何損失承擔任何責任。 重新委任首席執行官 上海復宏漢霖生物技術股份有限公司（「本公司」，與其附屬公司統稱「本集團」）董 事（「董事」）會（「董事會」）欣然宣佈於2025年8月29日（星期五）下午四時正假座 中國上海市徐匯區宜州路188號B8幢10樓會議室舉行的2025年第三次臨時股東會 （「臨時股東會」）之投票結果。 茲提述本公司日期為2025年8月12日之臨時股東會通告及有關臨時股東會的通函 （「通函」）及本公司日期為2025年8月15日有關臨時股東會的公告。除文義另有所 指外，本公告所用詞彙與通函所界定者具有相同涵義。 Shanghai Henlius Biotech, Inc. 上海復宏漢霖生物技術股份有限公司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：2696） 於2025年8月29日（星期五）舉行的 2025年第三次臨時股東會 所提呈決議案之投票結果 董事會專門委員會組成 重新委任董事會主席、監事會主席 ...

Core Viewpoint - The company, Fuhong Hanlin (02696), has seen a significant stock price increase following the announcement of successful clinical trials for its drug HLX43, indicating strong potential in the lung cancer treatment market [1] Group 1: Clinical Developments - Fuhong Hanlin has completed the first patient dosing in the U.S. for the international multicenter phase II clinical study of HLX43, a PD-L1 targeted antibody-drug conjugate for advanced non-small cell lung cancer (NSCLC) patients [1] - The company has had 10 lung cancer studies accepted for presentation at the 2025 World Conference on Lung Cancer (WCLC), focusing on three core innovative drugs: anti-PD-1 monoclonal antibody H drug, anti-EGFR monoclonal antibody HLX07, and the first PD-L1 ADC HLX43 entering phase II clinical trials globally [1] Group 2: Market Potential - Citigroup has indicated that Fuhong Hanlin will soon present the latest data on HLX43 at WCLC, which could further demonstrate its potential in treating NSCLC [1] - If HLX43 maintains an objective response rate (ORR) of 35% to 40% and a median progression-free survival (mPFS) of approximately 5.5 months in larger samples, the data will be highly persuasive [1]

Group 1 - The core viewpoint of the article highlights the positive market response to Fuhong Hanlin's recent clinical developments, with the stock price increasing over 8% during trading and closing at 77.95 HKD, reflecting a 5.34% gain [1] - Fuhong Hanlin has completed the first patient dosing in the U.S. for its HLX43, a PD-L1 antibody-drug conjugate, in a Phase II clinical trial for advanced non-small cell lung cancer (NSCLC) [1] - The company is evolving into an innovative biopharmaceutical firm centered around HLX43, as indicated by the cash flow generated from its biosimilars in China and globally [1] Group 2 - Fuhong Hanlin has had 10 lung cancer studies accepted for presentation at the 2025 World Conference on Lung Cancer (WCLC), focusing on three core innovative drugs: anti-PD-1 monoclonal antibody H drug, anti-EGFR monoclonal antibody HLX07, and the PD-L1 ADC HLX43 [1] - Citigroup anticipates that Fuhong Hanlin will present the latest data on HLX43 at WCLC, which could further demonstrate its potential in treating NSCLC [1] - If HLX43 maintains an objective response rate (ORR) of 35% to 40% and a median progression-free survival (mPFS) of approximately 5.5 months in larger samples, the data will be highly persuasive [1]

Core Viewpoint - Fosun Pharma is undergoing a critical phase of innovation transformation, with mixed financial results in the first half of 2025, showing a slight decline in revenue but significant growth in net profit [1][3]. Financial Performance - The company's revenue for the first half of 2025 was 19.514 billion yuan, a decrease of 4.63% compared to the same period last year [2]. - The net profit attributable to shareholders was 1.701 billion yuan, an increase of 38.96% year-on-year [2]. - The net profit after deducting non-recurring gains and losses was 960 million yuan, down 23.39% year-on-year [2]. - The net cash flow from operating activities was 2.134 billion yuan, an increase of 11.90% [2]. - As of the end of the reporting period, the net assets attributable to shareholders were 47.398 billion yuan, a slight increase of 0.29% [2]. Strategic Focus - The new leadership under Chairman Chen Yuqing has not altered the company's established strategy, which continues to focus on the "4 IN Strategy" (Innovation, Internationalization, Integration, and Intelligence) [4]. - The company is in a transitional phase, with a 5.29% decline in pharmaceutical business revenue to 13.901 billion yuan, while innovative drug revenue exceeded 4.3 billion yuan, growing by 14.26% [4]. Research and Development - Fosun Pharma invested 2.584 billion yuan in R&D during the first half of 2025, with three mature R&D entities focusing on different therapeutic areas [5]. - The company is positioning itself in the high-barrier nuclear medicine sector by establishing a new platform company for nuclear medicine products [6]. International Expansion - Overseas business is expected to be a significant support for future performance, with revenue from international markets reaching 5.478 billion yuan, accounting for 28.07% of total revenue [8]. - The company is expanding its presence in emerging markets such as the Middle East and Southeast Asia, leveraging local partnerships and registrations [8]. Asset Management - Fosun Pharma has been actively divesting non-core assets, with total signed disposal projects exceeding 2 billion yuan in 2025 [9]. - The company increased its stake in its subsidiary, Fosun Hani, from 59.56% to 63.43% by acquiring additional shares [10].

Core Viewpoint - Fosun Pharma is undergoing a critical phase of innovation transformation, with mixed financial results in the first half of 2025, showing a slight decline in revenue but significant growth in net profit [1][5]. Financial Performance - The company's revenue for the first half of 2025 was 19.514 billion yuan, a slight year-on-year decrease, while the net profit attributable to shareholders was 1.702 billion yuan, reflecting a year-on-year increase of 38.96% [1]. - The net profit after deducting non-recurring items was 0.961 billion yuan, a year-on-year decrease of 23.39% [1]. Strategic Focus - The new leadership under Chairman Chen Yuqing has not altered the existing strategic direction, which continues to focus on the "4 IN Strategy" (Innovation, Internationalization, Integration, and Intelligence) [5]. - The company aims to accelerate innovation speed and quality, as well as the breadth and depth of globalization, particularly in embracing AI [5]. Innovation and R&D - Fosun Pharma's R&D investment in the first half of 2025 totaled 2.584 billion yuan, with three mature R&D entities focusing on different therapeutic areas [6]. - The company is positioning itself in the nuclear medicine sector by investing in a new platform company, Chengdu Xingrui Jingxuan Biotechnology Co., Ltd., to develop integrated diagnostic and therapeutic nuclear medicine products [6]. International Business - Overseas revenue reached 5.478 billion yuan in the first half of 2025, accounting for 28.07% of total revenue, with a significant focus on markets in the U.S., Africa, and emerging regions like Southeast Asia and the Middle East [8]. - The subsidiary, Fuhong Hanlin, reported revenue of approximately 2.82 billion yuan, with overseas product profits more than doubling compared to the previous year [7][8]. Asset Management - The company has been actively divesting non-core assets, with total signed disposal projects exceeding 2 billion yuan in 2025 [9]. - Fosun Pharma has increased its stake in Fuhong Hanlin from 59.56% to 63.43% by acquiring shares from multiple sellers [10].

Core Viewpoint - 招银国际's report indicates that 复宏汉霖 (02696.HK) achieved a 3% year-on-year revenue increase to 2.82 billion RMB in the first half of the year, aligning with expectations, with drug sales reaching 2.57 billion RMB, representing 49% of the annual forecast [1] Financial Performance - Revenue for 复宏汉霖 in the first half of the year was 2.82 billion RMB, with drug sales contributing 2.57 billion RMB [1] - Net profit increased by 1% year-on-year to 390 million RMB, achieving 31% of the annual forecast [1] Market Position and Valuation - 招银国际 raised the target price for 复宏汉霖 from 61.98 HKD to 97.75 HKD, maintaining a "buy" rating [1] - The stock closed at 74.0 HKD, down 6.51%, with a trading volume of 2.5164 million shares and a turnover of 191 million HKD [1] - The market capitalization of 复宏汉霖 is 12.935 billion HKD, ranking 15th in the biopharmaceutical II industry [2] Analyst Ratings - Recent ratings from various investment banks include: - 国投证券: Buy, target price 93.45 HKD [1] - CMB International Capital: Buy, target price 97.75 HKD [1] - 中金公司: Outperform, target price 102.91 HKD [1] - 天风证券: Buy, target price 78.01 HKD [1] - 申万宏源: Buy, target price 71.00 HKD [1] Key Financial Metrics - 复宏汉霖's return on equity (ROE) is 27.33%, significantly higher than the industry average of -12.33% [2] - The company's net profit margin stands at 13.84%, compared to the industry's -555.02% [2] - Gross margin for 复宏汉霖 is 78.0%, while the industry average is 59.87% [2] - The company's debt ratio is 70.49%, lower than the industry average of 83.88% [2]

Core Viewpoint - 招银国际 reports that复宏汉霖 (02696) achieved a 3% year-on-year revenue increase to 2.82 billion RMB in the first half of the year, aligning with expectations [1] Financial Performance - Revenue from drug sales reached 2.57 billion RMB, accounting for 49% of the bank's annual forecast [1] - Net profit increased by 1% year-on-year to 390 million RMB, meeting 31% of the bank's annual forecast [1] Strategic Development - The company is evolving into an innovative biopharmaceutical firm led by HLX43, with ongoing cash inflows from its biosimilars in China and globally [1] Target Price Adjustment - 招银国际 raised its target price for the company from 61.98 HKD to 97.75 HKD, maintaining a "buy" rating [1]

Core Viewpoint - 招银国际 has raised the target price for复宏汉霖 (02696) to HKD 97.75, maintaining a "Buy" rating, reflecting confidence in the company's growth potential in the biopharmaceutical sector [1] Financial Performance - 复宏汉霖 reported a 3% year-on-year increase in revenue to RMB 2.82 billion, aligning with expectations [1] - Drug sales reached RMB 2.57 billion, accounting for 49% of the annual forecast by 招银国际 [1] - Net profit increased by 1% year-on-year to RMB 390 million, meeting 31% of the annual forecast [1] Strategic Development - The company is evolving into an innovative biopharmaceutical firm led by HLX43, with ongoing cash inflows from its biosimilars in China and globally [1]

Investment Highlights - The company is covered for the first time by CICC with an "outperform" rating and a target price of HKD 102.91, based on DCF valuation, positioning it as a leading innovative biopharmaceutical enterprise in China [1] - The company has adopted a dual strategy of innovation and internationalization, achieving domestic and international approvals for 6 and 4 products respectively by the end of 2024, establishing itself as a leader in domestic biopharmaceuticals [1] - Revenue has grown significantly from CNY 91 million in 2019 to CNY 5.724 billion, with a CAGR of 129%, while overseas revenue increased from CNY 2.62 million to CNY 678 million, expected to account for 11.9% of total revenue in 2024 [1] Innovation Pipeline - The company has developed a diverse innovation pipeline covering approximately 50 molecules, focusing on cutting-edge areas such as monoclonal antibodies, multi-antibodies, and ADCs [1] - HLX43 is the world's first PD-L1 ADC to enter clinical phase II, offering safety and competitive advantages, with low hematologic toxicity supporting its future use in first-line treatments and combination immunotherapy [1] - HLX22 has entered phase III international multicenter clinical trials for first-line treatment of advanced gastric cancer, with expectations to redefine standard therapies based on efficacy and safety data [1] Biosimilar Development - The company has a rich pipeline of biosimilars, leveraging first-mover advantages in the domestic market, with smooth commercialization progress anticipated [2] - It is expected that the domestic biosimilar procurement price reduction will be rational, allowing the company to achieve volume-based pricing [2] - The company has made strides in internationalization, with overseas revenue from Hanquyou reaching approximately CNY 120 million in 2024, a year-on-year increase of nearly 30%, and FDA approval achieved [2] Financial Forecast and Valuation - The company’s EPS is projected to be CNY 1.46 and CNY 1.55 for 2025 and 2026 respectively, with a CAGR of 1.2% [2] - Using a DCF valuation method with a WACC of 9.0% and a perpetual growth rate of 2.0%, the reasonable valuation for 2025 corresponds to a target price of HKD 102.91, implying an upside potential of 28.6% [2]

Investment Rating - The report assigns a "Buy-A" investment rating to the company, with a 6-month target price of HKD 93.45 [3][6]. Core Insights - The company reported a revenue of CNY 2.82 billion and a net profit of CNY 390 million for the reporting period [1]. - The early clinical data for PD-L1 ADC HLX43 is promising, showing high efficacy and low toxicity in treating various solid tumors, including non-small cell lung cancer (NSCLC) and thymic squamous cell carcinoma (TSCC) [1]. - The company is advancing multiple early-stage products with high potential, including HLX79, HLX701, HLX37, HLX97, HLX3901, HLX3902, HLX48, and HLX316, which are expected to progress in clinical trials [2]. Financial Projections - Revenue projections for 2025, 2026, and 2027 are CNY 5.88 billion, CNY 5.30 billion, and CNY 6.60 billion, respectively, with net profits of CNY 870 million, CNY 770 million, and CNY 1.34 billion [3][8]. - The company anticipates a significant increase in earnings per share (EPS) from CNY 1.60 in 2025 to CNY 2.46 in 2027 [8][14]. - The projected net profit margin is expected to rise from 14.74% in 2025 to 20.23% in 2027 [14]. Clinical Development - The company is actively conducting an international multi-center Phase II clinical trial for HLX43 in NSCLC and plans to initiate trials for thymic cancer and other solid tumors [1]. - The report highlights the potential of HLX43 to demonstrate efficacy across various patient populations without relying on biomarker selection [1]. Market Performance - The stock has shown significant relative and absolute returns over the past 1 month (28.5% and 34.8%), 3 months (85.7% and 99.3%), and 12 months (232.0% and 264.0%) [7].